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| 1 | Split liver transplantation: Current developments显示文摘In 1988, Rudolf Pichlmayr pioneered split liver transplantation(SLT), enabling the transplantation of one donor liver into two recipients-one pediatric and one adult patient. In the same year, Henri Bismuth and colleagues performed the first full right/full left split procedure with two adult recipients. Both splitting techniques were rapidly adopted within the transplant community. However, a SLT is technically demanding, may cause increased perioperative complications, and may potentially transform an excellent deceased donor organ into two marginal quality grafts. Thus, crucial evaluation of donor organs suitable for splitting and careful screening of potential SLT recipients is warranted. Furthermore, the logistic background of the splitting procedure as well as the organ allocation policy must be adapted to further increase the number and the safety of SLT. Under defined circumstances, in selected patients and at experienced transplant centers, SLT outcomes can be similar to those obtained in full organ LT. Thus, SLT is an important tool to reduce the donor organ shortage and waitlist mortality, especially for pediatric patients and small adults. The present review gives an overview of technical aspects, current developments, and clinical outcomes of SLT. | Christina Hackl Katharina M Schmidt Caner Süsal Bernd Dohler Martin Zidek Hans J Schlitt | 2018 | World Journal of Gastroenterology2018，24，47： | 20 |
| 2 | Correlation of lumbar lateral recess stenosis in magnetic resonance imaging and clinical symptoms显示文摘AIM To assess the correlation of lateral recess stenosis(LRS) of lumbar segments L4/5 and L5/S1 and the Oswestry Disability Index(ODI).METHODS Nine hundred and twenty-seven patients with history of low back pain were included in this uncontrolled study.On magnetic resonance images(MRI) the lateral recesses(LR) at lumbar levels L4/5 and L5/S1 were evaluated and each nerve root was classified into a 4-point grading scale(Grade 0-3) as normal,not deviated,deviated or compressed.Patient symptoms and disability were assessed using ODI.The Spearman's rank correlation coefficient was used for statistical analysis(P < 0.05).RESULTS Approximately half of the LR revealed stenosis(grade 1-3;52% at level L4/5 and 42% at level L5/S1) with 2.2% and 1.9% respectively reveal a nerve root compression.The ODI score ranged from 0%-91.11% with an arithmetic mean of 34.06% ± 16.89%.We observed a very weak statistically significant positive correlation between ODI and LRS at lumbar levels L4/5 and L5/S1,each bilaterally(L4/5 left:rho < 0.105,P < 0.01;L4/5 right:rho < 0.111,P < 0.01;L5/S1 left:rho 0.128,P < 0.01;L5/S1 right:rho < 0.157,P < 0.001).CONCLUSION Although MRI is the standard imaging tool for diagnosing lumbar spinal stenosis,this study showed only a weak correlation of LRS on MRI and clinical findings.This can be attributed to a number of reasons outlined in this study,underlining that imaging findings alone are not sufficient to establish a reliable diagnosis for patients with LRS. | Annina SplettstoBer M Fawad Khan Bernd Zimmermann Thomas J Vogl Hanns Ackermann Marcus Middendorp Adel Maataoui | 2017 | World Journal of Radiology2017，9，5： | 4 |
| 3 | 一种用于实时体绘制系统的自适应采样算法显示文摘本文讨论了一种用于体绘制的、支持基于空间跳跃和自适应光线终止等优化算法的高效硬件结构及一种加速半透明物体绘制的新技术 .这种硬件结构用于绘制规模为 2 5 6 3 体元的数据时可达到 70Hz的帧频 ,但这样的帧频只是在体元的透明度都被置为 0 (完全透明 )或 1(完全不透明 )的情况下才能取得 .引入新的加速技术后 ,绘制半透明物体的帧频也可接近上述数值 .新的加速技术采用自适应采样步长减少体绘制过程中冗余的体元重采样 ,从而使算法的复杂度和对存储器的带宽要求大大减小 .新的加速技术对半透明体数据可取得高达 4 7倍的加速比 .采用新的加速技术需要在开始交互绘制前对体数据进行距离编码 .优化后的距离编码对有 8兆体元的体数据的预处理时间仅需要 8~ | 夏放怀 沈振康 唐朝京 谌海新 Juergen Hesser Bernd Vettermann Reinhard Mnner | 2002 | 电子学报2002，30，3： | 3 |
| 4 | Quantification of human telomerase RNA (hTR) and human telomerase reverse transcriptase (hTERT) mRNA in testicular tissue of infertile patients显示文摘Aim: To evaluate the quantitative detection of human telomerase RNA (hTR) and human telomerase reverse transcriptase (hTERT) mRNA as diagnostic parameters in the workup of testicular tissue specimens from patients presenting with non-obstructive azoospemia. Methods: hTR and hTERT mRNA expression were quantified in 38 cryopreserved testicular tissue specimens by fluorescence real-time reverse transcription- polymerase chain reaction (RT-PCR)in a LightCycler(r). This was paralleled by conventional histological workup in all tissue specimens and additional semithin sectioning preparation in cases with maturation arrest ( n = 12) and Sertoli-cell-only syndrome ( n = 12). Results: The average normalized hTERT expression (NhTERT) Was 131.9 ± 48.0 copies (mean ± SD) in tissue specimens with full spermatogenesis, NhTERT = 51.2 ± 17.2 copies in those with maturation arrest and NhTERT = 2.7 ± 2.4 copies in those with Sertoli-cell-only syndrome (SCOS). The discriminant analysis showed that detection of NhTERT (NhTR) had a predictive value of 86.8 % (55.3 % ) for correct classification in one of the three histological subgroups.Conclusion: Our results demonstrate that quantitative detection of hTERT mRNA expression in testicular tissue enables a molecular-diagnostic classification of gametogenesis. Quantitative detection of hTERT in testicular biopsies is thus well suited for supplementing the histopathological evaluation. | Mark Schrader Markus Müller Rüdiger Heicappell Bernd Straub Kurt Miller | 2001 | Asian Journal of Andrology2001，3，4： | 3 |
| 5 | Digital templating in total hip arthroplasty:Additional anteroposterior hip view increases the accuracy显示文摘AIM To analyze planning total hip arthroplasty(THA) with an additional anteroposterior hip view may increases the accuracy of preoperative planning in THA.METHODS We conducted prospective digital planning in 100 consecutive patients: 50 of these procedures were planned using pelvic overview only(first group), and the other 50 procedures were planned using pelvic overview plus antero-posterior(a.p.) hip view(second group). The planning and the procedure of each patient were performed exclusively by the senior surgeon. Fifty procedures with retrospective analogues planning were used as the control group(group zero). After the procedure, the planning was compared with the eventually implanted components(cup and stem). For statistic analysis the x^2 test was used for nominal variables and the t test was used for a comparison of continuous variables.RESULTS Preoperative planning with an additional a.p. hip view(second group) significantly increased the exact component correlation when compared to pelvic overview only(first group) for both the acetabular cup and the femoral stem(76% cup and 66% stem vs 54% cup and 32% stem). When considering planning ± 1 size, the accuracy in the second group was 96%(48 of 50 patients) for the cup and 94% for the stem(47 of 50patients). In the analogue control group(group zero), an exact correlation was observed in only 1/3 of the cases.CONCLUSION Digital THA planning performed by the operating surgeon and based on additional a.p. hip view significantly increases the correlation between preoperative planning and eventual implant sizes. | Sophia K Stigler Franz J Müller Sebastian Pfaud Michael Zellner Bernd Füchtmeier | 2017 | World Journal of Orthopedics2017，8，1： | 3 |
| 6 | Spatio-temporal Variability of Soil Water at Three Seasonal Floodplain Sites: A Case Study in Tarim Basin,Northwest China显示文摘The floodplain vegetation of the Tarim River in Northwest China is strongly influenced by irrigated agriculture. The abstraction of river water disturbs the natural dynamics of the floodplain ecosystem. The human impact on the hydrological system by bank dams and the irrigation of cotton plantings have caused adverse changes of the Tarim River and its floodplains, so the current stocks of the typical Tugai vegetation show significant signs of degradation. Field studies of soils and statistical analysis of soil moisture data have shown that the vitality of the Tugai vegetation is primarily determined by its position to the riverbank and the groundwater. There exist complex interactions between soil hydrological conditions and the vitality of the vegetation. But the availability of water is not only influenced by the groundwater level and seasonal flood events. The spatial distribution of stocks at different states of vitality seems also to be decisively influenced by physical soil properties. Our results show that the water supply of plant communities is strongly influenced by the soil texture. Spatial differences of soil moisture and corresponding soil water tensions may be the decisive factors for the zonation of vegetation. Physical soil properties control the water retention and rising of capillary water from deeper soil layers and the phreatic zone and may supply the root systems of the phreatophytic vegetation with water. | Sven GRASHEY-JANSEN Martin KUBA Bernd CYFFKA müt HALIK Tayierjiang AISHAN | 2014 | Chinese Geographical Science2014，24，6： | 3 |
| 7 | Head-to-head comparison of N-terminal pro-brain natriuretic peptide, brain natriuretic peptide and N-terminal pro-atrial natriuretic peptide in diagnosing left ventricular dysfunction显示文摘 | Angelika Hammerer-Lercher Elke Neubauer Silvana Müller Otmar Pachinger Bernd Puschendorf Johannes Mair | 2001 | Clinica Chimica Acta2001，，2： | 2 |
| 8 | Parenteral emulsions stabilized with a mixture of phospholipids and PEG-660-12-hydroxy-stearate: evaluation of accelerated and long-term stability显示文摘 | Muhannad Jumaa Bernd W Müller | 2002 | European Journal of Pharmaceutics and Biopharmaceutics2002，，2： | 2 |
| 9 | Allogeneic partially HLA-matched dendritic cells pulsed with autologous tumor cell lysate as a vaccine in metastatic renal cell cancer显示文摘 | Anne Fl?rcken Joachim Kopp Antje van Lessen Kamran Movassaghi Anna Takvorian Korinna J?hrens Markus M?bs Constanze Sch?nemann Birgit Sawitzki Karl Egerer Bernd D?rken Antonio Pezzutto J?rg Westermann | 2013 | Human Vaccines & Immunotherapeutics2013，，： | 2 |
| 10 | TCO and light trapping in silicon thin film solar cells显示文摘 | Joachim Müller Bernd Rech Jiri Springer Milan Vanecek | 2004 | Solar Energy2004，，6： | 2 |
| 11 | Chronic hepatitis C:Treat or wait? Medical decision making in clinical practice显示文摘AIM:To analyzes the decision whether patients with chronic hepatitis C virus (HCV) infection are treated or not.METHODS:This prospective cohort study included 7658 untreated patients and 6341 patients receiving pegylated interferon α2 a/ribavirin,involving 434 physicians/institutions throughout Germany (377 in private practice and 57 in hospital settings).A structured questionnaire had to be answered prior to the treatment decision,which included demographic data,information about the personal life situation of the patients,anamnesis and symptomatology of hepatitis C,virological data,laboratory data and data on concomitant diseases.A second part of the study analyzes patients treated with pegylated interferon α2a.All questionnaires included reasons against treatment mentioned by the physician.RESULTS:Overall treatment uptake was 45%.By multivariate analysis,genotype 1/4/5/6,HCV-RNA ≤ 520 000 IU/mL,normal alanine aminotransferase (ALT),platelets ≤ 142 500/μL,age > 56 years,female gender,infection length > 12.5 years,concomitant diseases,human immunodeficiency virus co-infection,liver biopsy not performed,care in private practice,asymptomatic disease,and unemployment were factors associated with reduced treatment rate.Treatment and sustained viral response rates in migrants (1/3 of cohort) were higher than in German natives although 1/3 of migrants had language problems.Treatment rate and liver biopsy were higher in clinical settings when compared to private practice and were low when ALT and HCV-RNA were low.CONCLUSION:Some reasons against treatment were medically based whereas others were related to fears,socio-economical problems,and information deficits both on the side of physicians and patients. | Claus Niederau Dietrich Hüppe Elmar Zehnter Bernd Mller Renate Heyne Stefan Christensen Rainer Pfaff Arno Theilmeier Ulrich Alshuth Stefan Mauss | 2012 | World Journal of Gastroenterology2012，18，12： | 2 |
| 12 | Modeling of pharmacokinetic/pharmcodynamic (PK/PD) Relationships: Concepts and perspectives显示文摘 | Hartmut D Bernd M | 1999 | Pharm Res1999，16，： | 1 |
| 13 | Endothelial dysfunction is detectable in young normotensive first-degree delatives of subjects with type 2 diabetes in association with insulin resistance显示文摘 | Bernd M Balletshofer MD Kilian Rittig | 2000 | Circulation2000，101，15： | 1 |
| 14 | Lysyl Oxidase-like 1 Gene Polymorphisms in German Patients With Normal Tension Glaucoma, Pigmentary Glaucoma and Exfoliation Glaucoma显示文摘 | Christiane Wolf Eugen Gramer Bertram Müller-Myhsok Francesca Pasutto Gwendolyn Gramer Bernd Wissinger Nicole Weisschuh | 2010 | Journal of Glaucoma2010，，2： | 1 |
| 15 | Measuring velocity dispersion and attenuation in the exploration seismic frequency band显示文摘 | Langqiu F S Bernd M Douglas R S | 2009 | Geophysics2009，72，2： | 1 |
| 16 | Detrimental effects of tropisetron on permanent ischemie stroke in the rat 显示文摘 | Eduardo C J Eduardo M Bernd L F | 2008 | BMC Neuroscience2008，9，6： | 1 |
| 17 | Progress in evaluation of risk potential of ionic liquids--basis for all eco-design of sustainable products显示文摘 | BERND J KERSTIN M PETER B | 2005 | Green Chem2005，7，： | 1 |
| 18 | Characteristic perfusion pattern of osseous giant cell tumor in dynamic contrast-enhanced MRI显示文摘 | Libicher M Bernd L Schenk JP | 2001 | Radiologe2001，41，7： | 1 |
| 19 | Shippers' ecological buying behavior towards logistics services in France显示文摘 | BERND P DORIN M | 2011 | International Journal of Logisties: Research & Applications2011，14，6： | 1 |
| 20 | One of two different ADP-glucose pyrophosphorylase genes from potato responds strongly to elevated levels of sucrose显示文摘 | Bernd Thomas Müller-R?ber Jens Ko?mann L. Curtis Hannah Lothar Willmitzer Uwe Sonnewald | 1990 | MGG Molecular & General Genetics1990，，1： | 1 |
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