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| 1 | Implication of the intestinal microbiome in complications of cirrhosis显示文摘The intestinal microbiome(IM) is altered in patients with cirrhosis,and emerging literature suggests that this impacts on the development of complications.The Pub Med database was searched from January 2000 to May 2015 for studies and review articles on the composition,pathophysiologic effects and therapeutic modulation of the IM in cirrhosis.The following combination of relevant text words and MeS H terms were used,namely intestinal microbiome,microbiota,or dysbiosis,and cirrhosis,encephalopathy,spontaneous bacterial peritonitis,hepatorenal syndrome,variceal bleeding,hepatopulmonary syndrome,portopulmonary hypertension and hepatocellular carcinoma.The search results were evaluated for pertinence to the subject of IM and cirrhosis,as well as for quality of study design.The IM in cirrhosis is characterized by a decreased proportion of Bacteroides and Lactobacilli,and an increased proportion of Enterobacteriaceae compared to healthy controls.Except for alcoholic cirrhosis,the composition of the IM in cirrhosis is not affected by the etiology of the liver disease.The percentage of Enterobacteriaceae increases with worsening liver disease severity and decompensation and is associated with bacteremia,spontaneous bacterial peritonitis and hepatic encephalopathy.Lactulose,rifaximin and Lactobacillus-containing probiotics have been shown to partial y reverse the cirrhosis associated enteric dysbiosis,in conjunction with improvement in encephalopathy.The IM is altered in cirrhosis,and this may contribute to the development of complications associated with end-stage liver disease.Therapies such as lactulose,rifaximin and probiotics may,at least partially,reverse the cirrhosisassociated changes in the IM.This,in turn,may prevent or alleviate the severity of complications. | Mamatha Bhat Bianca M Arendt Venkat Bhat Eberhard L Renner Atul Humar Johane P Allard | 2016 | World Journal of Hepatology2016，8，27： | 13 |
| 2 | Resveratrol attenuates metabolic,sperm,and testicular changes in adult Wistar rats fed a diet rich in lipids and simple carbohydrates显示文摘High-fat diets affect male reproduction and sexual function.Therefore,we evaluated the effects of prolonged resveratrol administration on the metabolic,sperm,and testicular parameters of rats fed a cafeteria diet.Male Wistar rats were divided at weaning into control(Cv n=20)and cafeteria(CAF,n=16)groups.At 3 months,half of them were given daily supplementations of resveratrol(C-R,n=10;CAF-R,n=8)at a dosage of 30 mg kg-1 body mass for 2 months.Animals were killed at 5 months of age,and blood,spermatozoa,and testes were collected for further analysis.Data were analyzed by one-way ANOVA,and P<0.05 was considered statistically significant.The CAF diet promoted hyperglycemia(P<0.0001),and treatment with resveratrol reversed this condition(P<0.0001).The CAF diet reduced sperm viability and motility,while resveratrol improved these parameters(F<0.05).Regarding testicular morphology,the height of the seminiferous epithelium was reduced in the CAF group compared with that of the C group(P=0.0007).Spermatogenic cell proliferation was also reduced in the CAF group compared with that of the C group.However,the CAF-R showed an increase in cell proliferation rate compared with that of the untreated CAF group(P=0.0024).Although it did not modify body mass,the consumption of a CAF diet promoted hyperglycemia,adverse testicular morphology remodeling,and abnormal sperm,which were attenuated by treatment with resveratrol,thus suggesting a protective effect of this antioxidant on spermatogenesis. | Fabiana A de Oliveira Waldemar S Costa Francisco J B Sampaio Bianca M Gregorio | 2019 | Asian Journal of Andrology2019，21，2： | 2 |
| 3 | First and second generation biodiesels spray characteriza- tion in a diesel engine显示文摘 | Ezio Mancaruso Luigi Sequino Bianca M Vaglieco | 2011 | Fuel2011，90，9： | 1 |
| 4 | Knock Investiga- tion by Flame and Radical Species Detection in Spark Ignition Engine for Different Fuels 显示文摘 | Merola Simona S Vaglieco Bianca M | 2007 | Energy Conversion and Management2007，48，11： | 1 |
| 5 | Poland syndrome with bilateral features:case description with review of the literature显示文摘 | BABAN A TORRE M BIANCA S | 2009 | Am J Med Genet Part A2009，149，7： | 1 |
| 6 | Knock investigation by flame and radical species detection in spark ignition engine for different fuels显示文摘 | Bianca M Vaglieco B M | 2007 | Energy Conversion and Management2007，48，9： | 1 |
| 7 | TAXUS III Trial: In-Stent Restenosis Treated With Stent-Based Delivery of Paclitaxel Incorporated in a Slow-Release Polymer Formulation显示文摘 | Kengo Tanabe Patrick W. Serruys Eberhard Grube Pieter C. Smits Guido Selbach Willem J. van der Giessen Manfred Staberock Pim de Feyter Ralf Müller Evelyn Regar Muzaffer Degertekin Jurgen M.R. Ligthart Clemens Disco Bianca Backx Mary E. Russell | 2003 | Circulation: Journal of the American Heart Association2003，，： | 1 |
| 8 | Premixed combustion of GTL and RME fuels in a single cylinder research engine 显示文摘 | EZIO M BIANCA M V | 2012 | Applied Energy2012，91，： | 1 |
| 9 | Why do employees take more initiatives to improve their performance after co-deveh)ping performance measures? A field study显示文摘 | Bianca A C Marc J F Celeste P M | 2012 | Management ccounting Resem''ch2012，23，2： | 1 |
| 10 | pH-sensitive hydrogel based on a novel photocross-linkable copolymer 显示文摘 | Delia M Giovanna P Fabio S P Bianca C | 2004 | Biomacromolecules2004，5，5： | 1 |
| 11 | Re 'parity and the risk of Down's syndrome'显示文摘 | Clementi M Bianca S Tenconi R | 2004 | Am J Epidemiol2004，160，6： | 1 |
| 12 | Alignment of rod-shaped gold particles by electric fields显示文摘 | BIANCA M I VANDER Z GER J M | 1999 | Physical Chemistry B1999，103，： | 1 |
| 13 | INFγ stimulates arginine transport through system y^+L in human monocytes显示文摘 | BIANCA M R BUSSOLATIA O SALAA R | 2004 | FEBS Letters2004，571，： | 1 |
| 14 | Neuropeptide Y suppresses absence seizures in a genetic rat model显示文摘 | Leanne M S Terence J O Bianca J | 2005 | Brain Res2005，1033，2： | 1 |
| 15 | Experimental investigation on the combustion process in a spark ignition optically accessible engine fueled with methane/hydrogen blends 显示文摘 | SILVANA D ] PAOLO S BIANCA M V | 2014 | International journal of hydrogen energy2014，39，18： | 1 |
| 16 | A SolventlessCastor Oil-based PU Adhesive for Wood and Foam Substrates显示文摘 | BIANCA B R S RUTH M C S MARIA M C | 2010 | International Journal of Adhesion and Adhesives2010，，30： | 1 |
| 17 | Heavy metal uptake by barley growing in polluted soils: relationship With heavy metal speciation in soils 显示文摘 | Nicoletta C Bianca M P Massimiliano P | 2002 | Communications in Soil Science and Plant Analysis2002，33，12： | 1 |
| 18 | A new deletion in autosomal dominant guanosine triphosphate eyclohydrolase 1 deficiency gene-Segawa disease显示文摘 | Bianca S Bianca M | 2006 | J Neural Transm2006，113，2： | 1 |
| 19 | Comprehensive geriatric assessment,multifactorial interventions and nurse led care coordination to prevent functional decline in community dwelling older persons: protocol of a cluster randomized trial 显示文摘 | Jacqueline J Suijker Bianca M Buurman | 2012 | BMC Health Services Research2012，12，： | 1 |
| 20 | Analysis of Cell Type- Specific Responses Mediated by the Type IV Secretion System of Helicobacter py/or/显示文摘 | Bianca B Stefan M Sina B | | Infect Immun0，73，8： | 1 |
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