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| 1 | Implication of the intestinal microbiome in complications of cirrhosis显示文摘The intestinal microbiome(IM) is altered in patients with cirrhosis,and emerging literature suggests that this impacts on the development of complications.The Pub Med database was searched from January 2000 to May 2015 for studies and review articles on the composition,pathophysiologic effects and therapeutic modulation of the IM in cirrhosis.The following combination of relevant text words and MeS H terms were used,namely intestinal microbiome,microbiota,or dysbiosis,and cirrhosis,encephalopathy,spontaneous bacterial peritonitis,hepatorenal syndrome,variceal bleeding,hepatopulmonary syndrome,portopulmonary hypertension and hepatocellular carcinoma.The search results were evaluated for pertinence to the subject of IM and cirrhosis,as well as for quality of study design.The IM in cirrhosis is characterized by a decreased proportion of Bacteroides and Lactobacilli,and an increased proportion of Enterobacteriaceae compared to healthy controls.Except for alcoholic cirrhosis,the composition of the IM in cirrhosis is not affected by the etiology of the liver disease.The percentage of Enterobacteriaceae increases with worsening liver disease severity and decompensation and is associated with bacteremia,spontaneous bacterial peritonitis and hepatic encephalopathy.Lactulose,rifaximin and Lactobacillus-containing probiotics have been shown to partial y reverse the cirrhosis associated enteric dysbiosis,in conjunction with improvement in encephalopathy.The IM is altered in cirrhosis,and this may contribute to the development of complications associated with end-stage liver disease.Therapies such as lactulose,rifaximin and probiotics may,at least partially,reverse the cirrhosisassociated changes in the IM.This,in turn,may prevent or alleviate the severity of complications. | Mamatha Bhat Bianca M Arendt Venkat Bhat Eberhard L Renner Atul Humar Johane P Allard | 2016 | World Journal of Hepatology2016，8，27： | 13 |
| 2 | Acetylation of glycerol catalyzed by different solid acids显示文摘 | VALTER L C G BIANCA P P JOAO C S | 2008 | Catalysis Today2008，，133135： | 1 |
| 3 | The neutrophil-activating protein(HP-NAP)of Helicobacter pylori is a protective antigen and a majorvirulence factor显示文摘 | Satin B Del P G Della Bianca V | 2000 | The Journal of Experimental Medicine2000，191，9： | 1 |
| 4 | Hydrogen sulfide as a mediator of human corpus cavernosum smooth-muscle relaxation 显示文摘 | d'Emmanuele di Villa Bianca R Sorrentino R Maffia P | 2009 | Proc Natl Acad Sci USA2009，106，： | 1 |
| 5 | Hydrogen sulfide as a mediator of human corpus cavernosum smooth-muscle relaxation显示文摘 | d'Emmanuele di Villa Bianca R Sorrentino R Maffia P | 2009 | Proc Natl Acad Sci USA2009，106，11： | 1 |
| 6 | Why do employees take more initiatives to improve their performance after co-deveh)ping performance measures? A field study显示文摘 | Bianca A C Marc J F Celeste P M | 2012 | Management ccounting Resem''ch2012，23，2： | 1 |
| 7 | pH-sensitive hydrogel based on a novel photocross-linkable copolymer 显示文摘 | Delia M Giovanna P Fabio S P Bianca C | 2004 | Biomacromolecules2004，5，5： | 1 |
| 8 | Consumption of a novel dietary formula of plant sterol esters of canola oil fatty acids,in a canola oilmatrix containing 1,3-diacylglycerol,reduces oxidative stress in atherosclerotic apolipoprotein E-deficient mice显示文摘 | Bianca F Dotit P Yael H | | 0，，05： | 1 |
| 9 | Consumption of a novel dietary formula of plant sterol esters of canola oil fatty acids,in a canola oil matrix containing 1, 3-diacylglycerol, reduces oxidative stress in atherosclerotic apolipoprotein E-deficient mice 显示文摘 | BIANCA F DORIT P YAEL H | 2007 | J Agric Food Chem2007，55，5： | 1 |
| 10 | Fatigue analysis of damaged steel pipelines under cyclic internal pressure显示文摘 | Bianca de C Pinheiro Ilson P Pasqualino | 2009 | International Journal of Fatigue2009，31，1： | 1 |
| 11 | The importance of chitin in the marine environment显示文摘 | Claudiana P Souza Bianca C | 2011 | Marine Biotechnology2011，13，5： | 1 |
| 12 | Hypertonic environment elicits cyclooxygenase-2-driven prostaglandin E2 generation by colon cancer cells:role of cytosolic phospholipase A2-alpha and kinase signaling pathways显示文摘 | Luciana BG Bruno P Bianca CC | | 0，，： | 1 |
| 13 | Heavy metal uptake by barley growing in polluted soils: relationship With heavy metal speciation in soils 显示文摘 | Nicoletta C Bianca M P Massimiliano P | 2002 | Communications in Soil Science and Plant Analysis2002，33，12： | 1 |
| 14 | Human X-Box binding protein-1 confers both estrogen independence and antiestrogen resistance in breast cancer cell lines显示文摘 | BIANCA P REBECCA B AYESHA N | 2007 | FASEB J2007，21，： | 1 |
| 15 | Acetylation of glycerol catalyzed by different solid acids 显示文摘 | VALTER L C GONCALVES BIANCA P PINTO JOAO C SILVA | 2008 | Catalysis Today2008，，： | 1 |
| 16 | Pyrrolidine dithiocarbamate reduces renal dysfunction and injury caused by ischemia/reperfusion of the rat kidney显示文摘 | CHATTERJEE P K DI VILLA BIANCA R D SIVARAJAH A | 2003 | Eur J Pharmacol2003，482，13： | 1 |
| 17 | Epilepsy in cerebral glioma: timing of appearance and histological correlations 显示文摘 | Anna R Alessia T Bianca P | 2009 | J Neurooncol2009，93，3： | 1 |
| 18 | Hydrogen sulfide as a mediator of human corpus cavernosum smooth-muscle relaxation 显示文摘 | d' Emmanuele di Villa Bianca R Sorrentino R Maffia P Mirone V Imbimbo C Fusco F | 2009 | Proc Natl Acad Sci USA2009，106，： | 1 |
| 19 | A randomized clinical trail on a comprehensive geriatric assessment and intensive home follow - up after hospital discharge: the Transitional Care Bridge显示文摘 | Bianca Mb Juliette L P Bob A J D | 2010 | BMC Health Services Research2010，10，1： | 1 |
| 20 | Recurrent toxic hepatitis in a caucasian girl related to the use of Shou Wu Pian, a Chinese herbal preparation显示文摘 | Bianca P Dennis RW Piet MH etal | 2005 | J Pediatric Gastroenterol Nutri2005，41，： | 1 |
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