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| 1 | Sustainable functional urethral reconstruction:Maximizing early continence recovery in robotic-assisted radical prostatectomy显示文摘Objective:To evaluate the safety profile and short-term functional outcome of sustainable functional urethral reconstruction(SFUR)in robotic-assisted radical prostatectomy(RARP).Methods:One hundred and sixty-two consecutive prostate cancer patients who underwent RARP were retrospectively analyzed,in which 53 had undergone SFUR while the other 109 had undergone conventional RARP procedures.Immediate,2-week,1-month and 3-month continence recovery and other perioperative data were compared to evaluate short-term surgical and functional outcome.Results:The median age was 68 and 67 years in the experimental group and control group,respectively(pZ0.206),with a median prostate-specific antigen(PSA)of 13.6 ng/mL(interquartile range[IQR],8.46e27.32 ng/mL)in the experimental group and 13.84 ng/mL(IQR,9.12e26.80 ng/mL)in control group(pZ0.846).Immediate,2-week,1-month and 3-month continence recovery rates between the groups were 34.0%vs.3.7%,50.9%vs.14.7%,62.3%vs.27.5%,and 79.2%vs.63.3%(all p<0.05).The morphological changes made by the new reconstruction technique were maintained on magnetic resonance imaging(MRI)3 months postoperatively.Nerve-sparing procedures and adoption of the new reconstruction technique were significantly relevant to continence recovery on logistics regression model(p<0.001).Conclusions:SFUR is a safe and easy-to-handle modification that may contribute to early continence return for RARP.Long-term follow-up and prospective studies are required to further evaluate its value in postoperative quality-of-life improvement. | Zepeng Jia Yifan Chang Yan Wang Jing Li Min Qu Feng Zhu Huan Chen Bijun Lian Meimian Hua Yinghao Sun Xu Gao | 2021 | Asian Journal of Urology2021，8，1： | 2 |
| 2 | Experience of one single surgeon with the first 500 robot-assisted laparoscopic prostatectomy cases in China's Mainland显示文摘Objectives: To summarize the experience of the first 500 robot-assisted laparoscopicradical prostatectomy (RALP) cases by one surgeon and analyze the influencing factorsof functional and oncological outcomes.Methods: Between April 2012 and October 2017, 500 patients who underwent RALP wereincluded and divided sequentially into five equal groups. Patients’ preoperative, perioperativeand postoperative outcomes were analyzed and evaluated, and the Kruskal-Wallis test wasused to analyze and compare the effect of surgeon experience by case.Results: There is a statistically significant reduction in operative time, intraoperative estimatedblood loss and postoperative hospital stay time (all p<0.001) with the increased experience.The results show that experience was the most important influencing factor in bothoperative time and blood loss. Pelvic lymph node dissection (PLND) might increase the operativetime. The total positive surgical margin (PSM) rate was 21.8%. The PSM rate in pT3 tumorswas significantly higher than that in pT2 tumors (12.0% vs. 37.1%, p<0.001). The 5-yearbiochemical recurrence (BCR)-free rate was 70.8%. The results of Cox regression showed thatpreoperative prostate-specific antigen (PSA), postoperative Gleason score (GS), and pathologicT stage were independent risk factors for BCR.Conclusion: After approximately 200 cases, the surgeon reached a plateau for RALP, but theoutcomes could still improve after more cases. The surgeon’s experience was the most importantinfluencing factor for both operative time and blood loss. PSM rate was mainly determinedby tumor stage rather than by operation experience. | Huan Chen Bijun Lian Zhenyang Dong Yan Wang Min Qu Feng Zhu Yinghao Sun Xu Gao | 2020 | Asian Journal of Urology2020，7，2： | 1 |
| 3 | Re: Experience of one single surgeon with the first 500 robot-assisted laparoscopic prostatectomy cases in China's Mainland显示文摘Robotic-assisted laparoscopic prostatectomy(RALP)has maintained an essential role in the treatment of localized prostate cancer.The so-called“trifecta”including cancer control,urinary continence,and sexual potency are three goals that surgeons need to pay close attention to.The study demonstrated that RALP for patients in Asia is safe and feasible,and the effects of RALP are at least comparable,and superior to those of open surgery or laparoscopic surgery in functional and oncologic outcomes. | Huan Chen Bijun Lian Zhenyang Dong Yan Wang Min Qu Feng Zhu Yinghao Sun Xu Gao | 2020 | Asian Journal of Urology2020，7，2： | 0 |
| 4 | Graphene Quantum Dot‑Mediated Atom‑Layer Semiconductor Electrocatalyst for Hydrogen Evolution显示文摘The hydrogen evolution reaction performance of semiconducting 2H-phase molybdenum disulfide(2H-MoS_(2))presents a significant hurdle in realizing its full potential applications.Here,we utilize theoretical calculations to predict possible functionalized graphene quantum dots(GQDs),which can enhance HER activity of bulk MoS_(2).Subsequently,we design a functionalized GQD-induced in-situ bottom-up strategy to fabricate near atom-layer 2H-MoS_(2) nanosheets mediated with GQDs(ALQD)by modulating the concentration of electron withdrawing/donating functional groups.Experimental results reveal that the introduction of a series of functionalized GQDs during the synthesis of ALQD plays a crucial role.Notably,the higher the concentration and strength of electron-withdrawing functional groups on GQDs,the thinner and more active the resulting ALQD are.Remarkably,the synthesized near atom-layer ALQD-SO_(3)demonstrate significantly improved HER performance.Our GQD-induced strategy provides a simple and efficient approach for expanding the catalytic application of MoS_(2).Furthermore,it holds substantial potential for developing nanosheets in other transition-metal dichalcogenide materials. | Bingjie Hu Kai Huang Bijun Tang Zhendong Lei Zeming Wang Huazhang Guo Cheng Lian Zheng Liu Liang Wang | 2023 | Nano-Micro Letters2023，15，12： | 0 |
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