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| 1 | The abstracted and integrated Green functions and OOP of BEM in soil dynamics显示文摘It has been generally recognized that Green function integrated with Boundary Element Method (BEM) has advantages in dimensional reduction, high accuracy and satisfaction of the radiation condition at infinity, etc. Recently, the computational technique has rapidly developed and the orient-object programming has been widely applied, whereas the attribute ofion and the integration of Green function employed in BEM have not been discovered yet. In this work the abstrac- tion and integration of Green function are carried out for soil dynamics problems, and the procedure of the object-oriented calculation method is presented. Based on the Green function developed for the two-phase saturated medium, the re- sponse of the wave field to tunnel subjected to dynamic loading is calculated, and the transient solution as well as the time history of response is obtained. | DING BoYang YUAN JinHua PAN XiaoDong | 2008 | Science China(Physics,Mechanics & Astronomy)2008，51，12： | 4 |
| 2 | Solutions of Green's function for Lamb's problem of a two-phase saturated medium显示文摘The solutions of Green's function are significant for simplification of problem on a two-phase saturated medium.Using transformation of axisymmetric cylindrical coordinate and Sommerfeld's integral,superposition of the influence field on a free surface,authors obtained the solutions of a two-phase saturated medium subjected to a concentrated force on the semi-space. | Boyang Ding,and Jun Chen College of Civil Engineering and Architecture,Zhejiang University of Technology,Hangzhou 310014,China | 2011 | Theoretical & Applied Mechanics Letters2011，1，5： | 3 |
| 3 | Decoupling coefficients of dilatational wave for Biot's dynamic equation and its Green's functions in frequency domain显示文摘Green's functions for Biot's dynamic equation in the frequency domain can be a highly useful tool for the investigation of dynamic responses of a saturated porous medium. Its applications are found in soil dynamics, seismology, earthquake engineering,rock mechanics, geophysics, and acoustics. However, the mathematical work for deriving it can be daunting. Green's functions have been presented utilizing an analogy between the dynamic thermoelasticity and the dynamic poroelasticity in the frequency domain using the u-p formulation. In this work, a special term 'decoupling coefficient' for the decomposition of the fast and slow dilatational waves is proposed and expressed to present a new methodology for deriving the poroelastodynamic Green's functions. The correctness of the solution is demonstrated by numerically comparing the current solution with Cheng's previous solution. The separation of the two waves in the present methodology allows the more accurate evaluation of Green's functions, particularly the solution of the slow dilatational wave. This can be advantageous for the numerical implementation of the boundary element method(BEM) and other applications. | Boyang DING A.H.D.CHENG Zhanglong CHEN | 2016 | Applied Mathematics and Mechanics(English Edition)2016，37，1： | 2 |
| 4 | Coping with extremes:lowered myocardial phosphofructokinase activities and glucose content but increased fatty acids content in highland Eurasian Tree Sparrows显示文摘Background:Efficient and selective utilization of metabolic substrates is one of the key strategies in high-altitude animals to cope with hypoxia and hypothermia.Previous findings have shown that the energy substrate utilization of highland animals varies with evolutionary history and phylogeny.The heart is a proxy for the cardiopulmonary system,and the metabolic substrate utilization in the myocardium is also under the strong selective pressure of chronically hypoxic and hypothermic environments.However,little information is available on the physiological adjustments in relation to metabolic substrate utilization in the myocardium for coping with high-altitude environments.Methods:We compared the metabolic enzyme activities,including hexokinase(HK),phosphofructokinase(PFK),pyruvate kinase(PK),citrate synthase(CS),carnitine palmitoyl transferase 1(CPT-1),lactic dehydrogenase(LDH),and creatine kinase(CK),and metabolic substrate contents including glucose(Glu),triglyceride(TG),and free fatty acid(FFA)in the myocardium of a typical human commensal species,Eurasian Tree Sparrows(Passer montanus)between the Qinghai-Tibet Plateau(the QTP,3230 m)and low altitude population(Shijiazhuang,80 m),and between sexes.Results:Among the seven metabolic enzymes and three substrates investigated,we identified no significant differences in PK,CPT-1,HK,CS,LDH,and CK activities and TG content of the myocardium between high and low altitude populations.However,the QTP sparrows had significantly lower Glu content and PFK activities but higher FFA content relative to their lowland counterparts.In addition,male sparrows had higher myocardial HK and CS activities relative to females,independent of altitude.Conclusions:Our results showed that the QTP sparrows elevated fatty acid utilization rather than glucose preference in the myocardium relative to lowland counterpart,which contributes to uncovering both the physiological adjustments for adapting to the extreme conditions of the QTP,intraspecifically. | Boyang Ding Yuliang Zhao Yanfeng Sun Qian Zhang Mo Li Ghulam Nabi Yuefeng Wu Chuan Jiang Dongming Li | 2021 | Avian Research2021，12，4： | 1 |
| 5 | Intercellular transfer of activated STING triggered by RAB22A-mediated non-canonical autophagy promotes antitumor immunity显示文摘STING,an endoplasmic reticulum(ER)transmembrane protein,mediates innate immune activation upon cGAMP stimulation and is degraded through autophagy.Here,we report that activated STING could be transferred between cells to promote antitumor immunity,a process triggered by RAB22A-mediated non-canonical autophagy.Mechanistically,RAB22A engages PI4K2A to generate PI4P that recruits the Atg12–Atg5–Atg16L1 complex,inducing the formation of ER-derived RAB22A-mediated non-canonical autophagosome,in which STING activated by agonists or chemoradiotherapy is packaged.This RAB22A-induced autophagosome fuses with RAB22A-positive early endosome,generating a new organelle that we name Rafeesome(RAB22A-mediated non-canonical autophagosome fused with early endosome).Meanwhile,RAB22A inactivates RAB7 to suppress the fusion of Rafeesome with lysosome,thereby enabling the secretion of the inner vesicle of the autophagosome bearing activated STING as a new type of extracellular vesicle that we define as R-EV(RAB22A-induced extracellular vesicle).Activated STING-containing R-EVs induce IFNβrelease from recipient cells to the tumor microenvironment,promoting antitumor immunity.Consistently,RAB22A enhances the antitumor effect of the STING agonist diABZI in mice,and a high RAB22A level predicts good survival in nasopharyngeal cancer patients treated with chemoradiotherapy.Our findings reveal that Rafeesome regulates the intercellular transfer of activated STING to trigger and spread antitumor immunity,and that the inner vesicle of non-canonical autophagosome originated from ER is secreted as R-EV,providing a new perspective for understanding the intercellular communication of organelle membrane proteins. | Ying Gao Xueping Zheng Boyang Chang Yujie Lin Xiaodan Huang Wen Wang Shirong Ding Weixiang Zhan Shang Wang Beibei Xiao Lanqing Huo Youhui Yu Yilin Chen Run Gong Yuanzhong Wu Ruhua Zhang Li Zhong Xin Wang Qiuyan Chen Song Gao Zhengfan Jiang Denghui Wei Tiebang Kang | 2022 | Cell Research2022，32，12： | 1 |
| 6 | Solution of a Green's function for a saturated porous medium in a half-space subjected to a torsional force显示文摘Based on the solutions of the Green's function for a saturated porous medium obtained by the authors,and using transformation of axisymmetric coordinates,Sommerfeld integrals and superposition of the influence field on a free surface,the authors have obtained displacement solutions of a saturated porous medium subjected to a torsional force in a half-space.The relationship curves of the displacement solutions and various parameters(permeability,frequency,etc.)under action of a unit of torque are also given in this paper.The results are consistent with previous Reissner's solutions,where a two-phase medium decays to a single-phase medium.The solution is useful in solving relevant dynamic problems of a twophase saturated medium in engineering. | Ding Boyang Chen Jun Ouyang Ming | 2012 | Earthquake Engineering and Engineering Vibration2012，11，1： | 0 |
| 7 | Water resource conservation promotes synergy between economy and environment in China’s northern drylands显示文摘Water resource availability is the major limiting factor for sustainable development in drylands.Climate change intensifies the conflicting water demands between people and the environment and highlights the importance of effective water resource management for achieving a balance between economic development and environmental protection.In 2008,Inner Mongolia,typical dryland in northern China,proposed strict regulations on water exploitation and utilization aimed at achieving sustainable development.Our study is the first to investigate the effectiveness and performance of these long-standing water conservation regulations.Our analyses found that the regulations drove industrial transformation,evidenced by the decreasing proportion of environmentally harmful industries such as coal and steel,and the increasing proportion of tertiary industries(especially tourism).Following industrial transformation,economic development decoupled from industrial water consumption and subsequently led to reduced negative environmental impacts.Based on these results,adaptive strategies were developed for 12 cities by revealing and integrating their development pathways and relative status in achieving sustainable development.Integration and cooperation between cities were proposed,e.g.,a water trade agreement between eastern Inner Mongolia(an economically underdeveloped region with relatively abundant water resources)and central Inner Mongolia(an economically developed region with high water stress).Such an agreement may enable the holistic achievement of sustainable development across regions.By integrating the findings of our research,our study presents a reproducible framework for water-management-based sustainable development strategies in drylands. | Yali Liu Jianqing Du Boyang Ding Yuexian Liu Wenjun Liu Anquan Xia Ran Huo Qinwei Ran Yanbin Hao Xiaoyong Cui Yanfen Wang | 2022 | Frontiers of Environmental Science & Engineering2022，16，3： | 0 |
| 8 | Research progress on protective coatings against molten nitrate salts for thermal energy storage in concentrating solar power plants显示文摘Concentrating solar power(CSP) has garnered considerable global attention as a reliable means of generating bulk electricity, effectively addressing the intermittent nature of solar resources.The integration of molten salt technology for thermal energy storage(TES) has further contributed to the growth of CSP plants;however, the corrosive nature of molten salts poses challenges to the durability of container materials, necessitating innovative corrosion mitigation strategies.This review summarizes scientific advancements in high-temperature anticorrosion coatings for molten nitrate salts, highlighting the key challenges and future trends.It also explores various coating types, including metallic, ceramic, and carbon-based coatings, and compares different coating deposition methods.This review emphasizes the need for durable coatings that meet long-term performance requirements and regulatory limitations, with an emphasis on carbon-based coatings and emerging nanomaterials.A combination of multiple coatings is required to achieve desirable anticorrosion properties while addressing material compatibility and cost considerations.The overall goal is to advance the manufacturing, assembly, and performance of CSP systems for increased efficiency, reliability, and durability in various applications. | HOU Wenjie Maria Elena Navarro Rivero PAN Jin ZOU Boyang Benjamin Grégoire Anabel Palacios DING Yulong | 2023 | Baosteel Technical Research2023，17，4： | 0 |
| 9 | Effect of Different Drying Processes on Active Ingredients of Rheum officinale Baill.显示文摘[Objectives]To determine the drying process of different functional rhubarbs.[Methods]The contents of tannins,bianthrone,free anthraquinones and combined anthraquinones in medicinal rhubarb were determined by HPLC.The results were analyzed by two-way analysis of variance.[Results]Under different drying conditions,the contents of tannins,bianthrone,free anthraquinones and combined anthraquinones in medicinal rhubarb were significantly different.Taking the tannins content as the index,the optimum drying condition of the rhizome is 1 cm thick,dried at 60℃,the root is cut 1 cm thick,and dried at 30℃;the bianthrone content is used as an indicator,the rhizome is optimally dried.The condition is to cut 1 cm thick,dry at 60℃,the root is cut to 5 cm thick,and dried at 40℃;the free anthraquinones content is used as an index,and the optimum drying condition of the rhizome is 3 cm thick and dried at 50℃.The root is cut to a thickness of 3 cm and dried at 30℃.The combine anthraquinones content is used as an indicator.The optimum drying conditions for the rhizome are 5 cm thick,dried at 40℃,and the root is cut to 5 cm thick and dried at 70℃.[Conclusions]Different functional components of rhubarb have different directional processing methods.The drying process can reduce the drying temperature or increase the thickness of the slice,and the directional processing of the diarrhea-type rhubarb can be processed.The drying process can be carried out by increasing the drying temperature or reducing the thickness of the slice directed processing of heat-clearing and purging-fire rhubarb. | Yiming DING Tong SHANG Yue SHI Boyang PENG Ting ZHAO Yuan ZHANG Li LI Shengli WEI | 2020 | Medicinal Plant2020，11，6： | 0 |
| 10 | Tumor necrosis factor-stimulated gene-6 ameliorates early brain injury after subarachnoid hemorrhage by suppressing NLRC4 inflammasome-mediated astrocyte pyroptosis显示文摘Subarachnoid hemorrhage is associated with high morbidity and mortality and lacks effective treatment.Pyroptosis is a crucial mechanism underlying early brain injury after subarachnoid hemorrhage.Previous studies have confirmed that tumor necrosis factor-stimulated gene-6(TSG-6)can exert a neuroprotective effect by suppressing oxidative stress and apoptosis.However,no study to date has explored whether TSG-6 can alleviate pyroptosis in early brain injury after subarachnoid hemorrhage.In this study,a C57BL/6J mouse model of subarachnoid hemorrhage was established using the endovascular perforation method.Our results indicated that TSG-6 expression was predominantly detected in astrocytes,along with NLRC4 and gasdermin-D(GSDMD).The expression of NLRC4,GSDMD and its N-terminal domain(GSDMD-N),and cleaved caspase-1 was significantly enhanced after subarachnoid hemorrhage and accompanied by brain edema and neurological impairment.To explore how TSG-6 affects pyroptosis during early brain injury after subarachnoid hemorrhage,recombinant human TSG-6 or a siRNA targeting TSG-6 was injected into the cerebral ventricles.Exogenous TSG-6 administration downregulated the expression of NLRC4 and pyroptosis-associated proteins and alleviated brain edema and neurological deficits.Moreover,TSG-6 knockdown further increased the expression of NLRC4,which was accompanied by more severe astrocyte pyroptosis.In summary,our study revealed that TSG-6 provides neuroprotection against early brain injury after subarachnoid hemorrhage by suppressing NLRC4 inflammasome activation-induced astrocyte pyroptosis. | Mingxiang Ding Lei Jin Boyang Wei Wenping Cheng Wenchao Liu Xifeng Li Chuanzhi Duan | 2024 | Neural Regeneration Research2024，19，5： | 0 |
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