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| 1 | Quality of life, physical performance and nutritional status in older patients hospitalized in a cardiology department显示文摘Objectives Quality of life(QoL) is a priority outcome in older adults suffering from cardiovascular diseases. Frailty and poor nutritional status may affect the QoL through mobility disorders and exhaustion. The objective of this study was to determine if physical frailty and nutritional status were associated with QoL, in older cardiology patients. Methods Cross sectional, observational study conducted in a cardiology department from a university hospital. Participants(n = 100) were aged 70 and older. Collected data included age, sex, cardiac diseases, New York Heart Association(NYHA) classification, comorbidities(Charlson Index) and disability. A Short Physical Performance Battery(SPPB), including walking speed assessment was performed;handgrip strength were measured as well as Fried’s frailty phenotype. Nutritional status was assessed using the Mini Nutritional Assessment(MNA) and Body Mass Index(BMI), inflammation by C-reactive protein(CRP). QoL was assessed using the EORTC–QLQ questionnaire. Univariate and multivariate analyses were performed to study the associations between all recorded parameters and QoL. Results In participants(mean age: 79.3 ± 6.7 years;male: 59%), Charlson index, arrhythmia, heart failure, NYHA class III-IV, MNA, disability, walking speed, SPPB score, frailty and CRP were significantly associated with QoL in univariate analysis. Multivariate analysis showed that NYHA class III-IV(P < 0.001), lower MNA score(P = 0.03), frailty(P < 0.0001), and higher CRP(P < 0.001) were independently associated with decreased QoL. Conclusions Frailty, nutritional status and inflammation were independently associated with poor QoL. Further studies are needed to assess the efficacy of nutritional and physical interventions on QoL in this population. | Matthieu Lilamand Mariannick Saintout Marie Vigan Astrid Bichon Laure Tourame Aurélie Brembilla Diet Bernard Iung Dominique Himbert Cédric Laouenan Agathe Raynaud-Simon | 2020 | Journal of Geriatric Cardiology2020，17，7： | 3 |
| 2 | c-Cbl expres-sion levels regulate the functional responses of hu-man central and effector memory CD4Tcells显示文摘 | Brembilla NC Weber J Rimoldi D | 2008 | Blood2008，112，3： | 1 |
| 3 | Postoperative ventricular arrhythmias after cardiac surgery:immediate-and long-term significance显示文摘 | Brembilla PB Villemot JP Carteaux JP | 2003 | Pacing Clin Electrophysiol2003，26，21： | 1 |
| 4 | Are the results of elec- tropysiological study different in the patients with a pre - excitation syn- drome, with and without syn cope 显示文摘 | Brembilla PB Chomelon F Groben L | 2008 | Europace2008，10，5： | 1 |
| 5 | Synthesis of New Amphiphilic Cationic Block Copolymers and Study of Their Behaviour in Aqueous Medium as Regards Hydrophobic Microdomain Formation显示文摘 | Fischer A Brembilla A Lochon P | 2001 | Polymer2001，42，： | 1 |
| 6 | Molecular cloning of the o2-m5 allele of Zea mays using transposon marking显示文摘 | M. Motto M. Maddaloni G. Ponziani M. Brembilla R. Marotta N. Fonzo C. Soave R. Thompson F. Salamini | 1988 | MGG Molecular & General Genetics1988，，3： | 1 |
| 7 | Activation of the aryl hydrocarbon receptor reveals distinct require- ments for IL-22 and IL-17 production by human T helper cells显示文摘 | Ramirez JM Brembilla NC Sorg O | 2010 | Eur J Immunol2010，40，9： | 1 |
| 8 | Diamino-3,4 Phenylalcanes Transform to Benzimidazolemethylthiols-2显示文摘 | Roizard D Brembilla A Lochon Pi | 1989 | Bulletin de la Societe Chimique de France1989，，3： | 1 |
| 9 | The b-32 protein from maize endosperm, an albumin regulated by the 02 locus: nucleic acid(cDNA) and amino acid sequences显示文摘 | Fonzo N D Hartings H Brembilla M | 1988 | Molecular and General Genetics1988，212，3： | 1 |
| 10 | Synthesis of new amphiphilic cationic block copolymers and study of their behaviour in aqueous medium as regards hydrophobic microdomain formation显示文摘 | Brembilla A Lochon P | 2001 | Polymer2001，42，： | 1 |
| 11 | Synthesis of new amphiphilic cationic block copolymers and study of their behaviour in aqueous medium as regards hydrophobic microdomain formation显示文摘 | Fischer A Brembilla A Lochon P | 2001 | Polymer2001，42，： | 1 |
| 12 | Activation of the aryl hy-drocarbon receptor reveals distinct requirements for IL-22 and IL-17 production by human T helper cells显示文摘 | Ramirez J M Brembilla N C Sorg O | 2010 | Eur J Immunol2010，40，9： | 1 |
| 13 | Interleukin-17A+ cell counts are increased in systemic sclerosis skin and their number is inversely correlated with the extent of skin involvement显示文摘 | Truchetet ME Brembilla NC Montanari E | 2013 | Arthritis Rheum2013，65，5： | 1 |
| 14 | Diamino - 3, 4 Phenylalcanes Transform to Benzlmidazolem - ethyhhiols - 2 显示文摘 | Roizard D Brembilla A Lochon P | 1989 | Bulletin de la Societe Chimique de France1989，，3： | 1 |
| 15 | Increased frequency of circulating Th22 in addition to Th17 and Th2 lymphocytes in systemic sclerosis:association with interstitial lung disease显示文摘 | Truchetet ME Brembilla NC Montanari E | 2011 | Arthritis Res Ther2011，13，5： | 1 |
| 16 | Synthesis of new amphiphilic cationic block copolymers and study of their behaviour in aqueous medium as regards hydrophobic microdomain formation 显示文摘 | Fischer A Brembilla A Lochon P | 2001 | Polymer2001，42，： | 1 |
| 17 | Synthesis of new amphi- philic cationic block copolymers and study of their behaviour in aqueous medium as regards hydrophobic microdomain formation显示文摘 | Fischer A Brembilla A Loehon P | 2001 | Polymer2001，42，： | 1 |
| 18 | Postoperative ventrieular arrhythmias after cardiac surgery:, immediate and long-term significance 显示文摘 | Brembilla PB Villemot JP Carteaux JP | 2003 | Pacing Clin Electrophysiol2003，26，2： | 1 |
| 19 | Nitroxide-mediated radical polymerization of 4-vinylpyridine: Study of the pseudo-living character of the reaction and influence of temperature and nitroxide concentration显示文摘 | FISCHER A BREMBILLA A LOCHON P | 1999 | Macromolecules1999，32，： | 1 |
| 20 | Synthesis of new amphiphilic cationic block copolymers and study of their behaviour in aqueous medium as regards hydrophobic microdomain formation显示文摘 | Fischer A Brembilla A Lochon P | 2001 | Polymer2001，42，： | 1 |
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