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| 1 | Efficacy of neoadjuvant therapy and surgical rescue for locally advanced hepatoblastomas:10 year single-center experience and literature review显示文摘AIM:To report our experience with long-term outcomes after multimodal management therapy.METHODS:An observational retrospective study was performed containing seven patients with hepatoblastoma(Hbl)treated in our institution,a tertiary referral center,from 2003 to 2011.Demographic,preoperative,surgical,and outcome variables were collected.A survival analysis and a review of the current literature related to combination neoadjuvant chemotherapy and surgical resection on Hbl were performed.RESULTS:The median age at surgery was 14.4 mo,with a male to female ratio of 4:3.Pretext staging at diagnosis was as follows:stageⅠ,4 cases;stageⅡ,2 patients;and stageⅢ,1 case.Mean pretreatment tumor volume was 735 cm3.Five out of seven patients received neoadjuvant chemotherapy according to SIOPEL-3 or SIOPEL-6 protocols.Tumor volume and alphafetoprotein levels significantly dropped after neoadjuvant therapy.Surgical procedures performed included hemihepatectomies,segmentectomies and atypical resection.All patients received chemotherapy after surgery.Median postoperative hospital stay was 8 d.All patients were alive and disease-free after a median follow-up period of 23 mo.With regards to the literature review,seventeen articles were found that were related to our search.CONCLUSION:Our series shows how multimodal management of Hbl,exhaustive control and a meticulous surgical approach leads to almost 100%complete resection with optimal postoperative results. | Dolores Ayllon Teran Oscar Gómez Beltran Rubén Ciria Bru Elena Mateos González María José Pea Rosa Antonio Luque Molina Pedro López Cillero Javier Briceo Delgado | 2014 | World Journal of Gastroenterology2014，20，29： | 12 |
| 2 | Albumin and proximal tubular cells-beyond endocytosis显示文摘 | | 2000 | Nephrol dial transplant2000，15，： | 1 |
| 3 | IR laser produc- tion of nanostruetured polyborocarbosiloxane powders with Si O B bonds显示文摘 | Pola J Herlin-Boime N Brus J | 2005 | Solid State Sciences2005，7，1： | 1 |
| 4 | Clinical events after transjugular intrahepatic portosystemic shunt: Correlation with hemodynamic findings显示文摘 | Marta Casado Jaume Bosch Juan Carlos García-Pagán Conxita Bru Rafael Ba?ares Juan Carlos Bandi Angels Escorsell José Manuel Rodríguez-Láiz Rosa Gilabert Faust Feu Carlos Schorlemer Antonio Echenagusia Joan Rodés | 1998 | Gastroenterology1998，，6： | 1 |
| 5 | Specific immunity induction at the mucosal level by viable Lactobacillus casei:Aperspective for oral vaccine development显示文摘 | Gobbato N Bru E | 1998 | Food & Agri Immunol1998，，10： | 1 |
| 6 | Symmetric singuiar linear control systems显示文摘 | Bru R Coll C Thom E N | 2002 | Applied Mathematics letters2002，15，： | 1 |
| 7 | Group inverse and group involutory matrices显示文摘 | Bru R Thom E N | 1998 | Linear and multilinear Algebra1998，45，： | 1 |
| 8 | IR laser production of nanostructured polyborocarbosiloxane powders with Si-O-B bonds显示文摘 | Pola J Herlin-Boime N Brus J | 2005 | Solid State Sciences2005，7，1： | 1 |
| 9 | Occult hepatitis B virus infection in the setting of hepatitis C virus(HCV) and human immunode ficiency virus(HIV) co-infection:clinically relevant or a diagnostic problem显示文摘 | Rodriguez TM Gonzalez GJ Bru N | 2007 | J Med Virol2007，79，5： | 1 |
| 10 | IR laser production of nanostructured polyborocarbosiloxane powders with Si-O-B bonds显示文摘 | POLA J HERL1N N BRUS J | 2005 | Solid StateSciences2005，7，： | 1 |
| 11 | Dipyrone interference on several common biochemical tests显示文摘 | Gascon N Otal C Martinez- Bru C | 1993 | Chem1993，39，6： | 1 |
| 12 | Symmetric singular linear control systems显示文摘 | Bru R Coll C Thome N | 2002 | Applied Mathematics Letters2002，15，： | 1 |
| 13 | Systemic inflammatory response and serum lipopolysaccharide levels predict multiple organ failure and death in alcoholic hepatitis显示文摘 | Javier Michelena José Altamirano Juan G. Abraldes Silvia Affò Oriol Morales‐Ibanez Pau Sancho‐Bru Marlene Dominguez Juan Carlos García‐Pagán Javier Fernández Vicente Arroyo Pere Ginès Alexandre Louvet Philippe Mathurin Wajahat Z. Mehal Juan Caballería Ram | 2015 | Hepatology2015，，3： | 1 |
| 14 | Individual responsesto firm failure: appraisals,grief, and the influenceof prior failure experience显示文摘 | JENKINS A S W IKLUND J BRU N D IN E | 2014 | Journal of Business Venturing2014，29，1： | 1 |
| 15 | Evidence for shifts in the structure and abundance of the microbial community in a long-term PCB-contaminated soil under bioremediation显示文摘 | Petrie I Bru D Udikovic-Kolic N | 2011 | Journal of Hazardous Materials2011，195，15： | 1 |
| 16 | T-cell regulation in chronic paranasal sinus disease显示文摘 | Van Bru Aene N Perez-Novo CA Basins-Ki TM | 2008 | J Allergy Clin Immunol2008，121，： | 1 |
| 17 | Aspirin versus indomethacin treatment of patent ductus arteriosus in the preterm neonate with respiratory distress syndrome 显示文摘 | Van Overmeire B Brus F Van Acker K J Van der Auwera JC Schasfoort M Elzenga N J | 1995 | Pediatr Res1995，38，6： | 1 |
| 18 | A probabilistic Hough transform显示文摘 | KIRYATI N ELDAR Y BRU CKSTE IN AM | 1991 | Pattern Recognition1991，24，： | 1 |
| 19 | Specific immunity induction at the mucosal level by viable Lactobacillus casei : a perspective for oral vaccine development 显示文摘 | ALVAREZ S GOBBATO N BRU E | 1998 | Food & Agri Immunol1998，10，1： | 1 |
| 20 | Specific immunity induction at the mucosal level by viable Lactobacillus casei : Aperspective for oral vaccine development 显示文摘 | Alvarez S Gobbato N Bru E | 1998 | Food and Agri Immunol1998，，10： | 1 |
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