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| 1 | Differing profiles of people diagnosed with acute and chronic hepatitis B virus infection in British Columbia,Canada显示文摘AIM To describe the characteristics of people diagnosed with acute and chronic hepatitis B virus(HBV) infection in British Columbia(BC).METHODS We used data from the BC Hepatitis Testers Cohort(BCHTC),which includes all individuals tested for hepatitis C virus(HCV) or human immunodeficiency virus(HIV) or those diagnosed with HBV or active tuberculosis in BC since 1990.These data were integrated with prescription drug,medical visit,hospitalization and mortality data.HBV cases were classified as acute or chronic according to provincial guidelines.We compared characteristics of individuals by HBV infection group(acute,chronic and negative).Factors associated with acute or chronic HBV infection were assessed with multinomial logistic regression models in comparison to the HBV negative group.RESULTS46498 of the 1058056 eligible BC-HTC participants were diagnosed with HBV infection.4.3% of HBV positive individuals were diagnosed with acute HBV infections while 95.7% had chronic infections.Problematic alcohol use,injection drug use,and HIV or HCV co-infection were more common among individuals diagnosed with acute HBV compared to those with chronic infections and HBV negative individuals.In multivariable multinomial logistic regression models,we observed significant associations between acute or chronic HBV diagnosis and being male,age at HBV diagnosis or birth cohort,South and East Asian ethnicity,HCV or HIV infection,and injection drug use.The odds of acute HBV decreased with increasing age among people who inject drugs,while the opposite was true for chronic HBV.Persons with acute HBV were predominantly White(78%) while those with chronic HBV were mostly East Asian(60%).Relative to Whites,East Asians had 12 times greater odds of being diagnosed with chronic HBV infection.These odds increased with increasing socioeconomic deprivation.CONCLUSION Differences in the profiles of people diagnosed with acute and chronic HBV infection necessitate differentiated screening,prevention,care and treatment programs. | Mawuena Binka Zahid A Butt Stanley Wong Mei Chong Jane A Buxton Nuria Chapinal Amanda Yu Maria Alvarez Maryam Darvishian Jason Wong Gina McGowan Mikhail Torban Mark Gilbert Mark Tyndall Mel Krajden Naveed Z Janjua | 2018 | World Journal of Gastroenterology2018，24，11： | 3 |
| 2 | A qualitative study of qual- ity of life after stroke: The importance of social relationships显示文摘 | Lynch EB Butt Z Heinemann A | 2008 | J Rehabil Med2008，40，7： | 1 |
| 3 | Daily iron supplementation is more effective than twice weekly iron supplementation in pregnant women in Pakistan in a randomized double-blind clinical trial显示文摘 | MUMTAZ Z SHAHAB S BUTT N | 2000 | J Nutr2000，130，11： | 1 |
| 4 | Color Doppler imaging in untreated high-and normal-pressure open-angle glaucoma显示文摘 | Butt Z O'Brien C McKillop G | 1997 | Invest Ophthalmol Vis Sci1997，38，3： | 1 |
| 5 | Cholelithiasis in hepatic cirrhosis:evaluating the role of risk factors显示文摘 | Butt Z Hyder Q | | 0，，： | 1 |
| 6 | Increased quality of life among hepatocellular carcinoma patients treated with ra- dioembohzation,compared with chemoembolization显示文摘 | Salem R Gilbertsen M Butt Z | 2013 | Clin Gas- troenterol Hepato12013，11，10： | 1 |
| 7 | The effect of seal oil on paclitaxel induced cytotoxicity and apoptosis in breast carci- noma MCF-7 and MDA-MB-231 cell lines 显示文摘 | Wang Z Butt K Wang L | 2007 | Nutr Canc- er2007，58，2： | 1 |
| 8 | Do Economic Fac- tors Influence Stock Returns? A Firm and Industry Level Anal- ysis 显示文摘 | Butt B Z Rehman K U Khan M A | 2010 | African Journal of Business Management2010，4，5： | 1 |
| 9 | Temporal precision in the neural code and the time scales of nature vision显示文摘 | BUTTS D A WENG C JIN J Z | 2007 | Nature2007，449，： | 1 |
| 10 | Is depression an inflammatory con- dition? A review of available evidence 显示文摘 | Hashmi AM Butt Z Umair M | 2013 | J Pak Med Assoc2013，63，： | 1 |
| 11 | Xylanases and their applications in baking industry显示文摘 | Butt MS Tahir-Nadeem M Ahmad Z | 2008 | Food Technol Biotech2008，46，1： | 1 |
| 12 | Apical margins after robot-assisted radical prostatectomy: does technique matter?显示文摘 | Guru K A Perlmutter A E Sheldon M J Butt Z M Zhang S Tan W | 2009 | J Endourol2009，23，： | 1 |
| 13 | A review of quality of life instruments used in liver transplantation显示文摘 | Jay C L Butt Z Ladner D P | 2009 | J Hepa- tol2009，51，5： | 1 |
| 14 | Prospective longitudinal evaluation of a symptom cluster in breast cancer显示文摘 | Sanford SD Beaumont JL Butt Z | 2013 | J Pain Symptom Manage2013，20，： | 1 |
| 15 | Synthesis and characterization of some novel aromatic polyimides显示文摘 | Saeed Butt M Akhtar Z Zafar-uz-Zarnan M | 2005 | Eur Polym J2005，41，7： | 1 |
| 16 | Color Doppler imaging in untreated high-and normal pressure open-angle glaucoma 显示文摘 | O'Brien C McKillop G | 1997 | Invest Ophthalmol Vis Sci1997，38，： | 1 |
| 17 | Linear programming SVM-ARMA2K with application in engine system identification显示文摘 | LU Z SUN J BUTTS K | | 0，，04： | 1 |
| 18 | Increased quality of lifeamong hepatocellular carcinoma patients treated withradioembolization,compared with chemoembolization 显示文摘 | Salem R Gilbertsen M Butt Z | 2013 | ClinGastroenterol Hepatol2013，11，10： | 1 |
| 19 | Astrocytes and NG2-glia:what's in a name显示文摘 | Nishiyama A Yang Z Butt A | | 0，，06： | 1 |
| 20 | Mortality in meconium aspiration syndrome in hospitalized babies显示文摘 | Anwar Z Butt TK Kazi MY | 2011 | J Coil Physicians Surg Pak2011，21，11： | 1 |
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