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| 1 | DAPT Enhances the Apoptosis of Human Tongue Carcinoma Cells显示文摘Aim To investigate the effect of DAPT(γ-secretase inhibitor) on the growth of human tongue carcinoma cells and to determine the molecular mechanism to enable the potential application of DAPT to the treatment of tongue carcinoma. Methodology Human tongue carcinoma Tca8113 cells were cultured with DAPT.Cell growth was determined using Indigotic Reduction method.The cell cycle and apoptosis were analyzed by flow cytometry.Real-time PCR and Immuno-Fluorescence(IF) were employed to determine the intracellular expression levels. Results DAPT inhibited the growth of human tongue carcinoma Tca8113 cells by inducing G_0-G_1 cell cycle arrest and apoptosis.The mRNA levels of Hairy/Enhancer of Split-1(Hes-1),a target of Notch activation,were reduced by DAPT in a dose-dependent manner.Coincident with this observation,DAPT induced a dose-dependent promotion of constitutive Caspase-3 in Tca8113 cells. Conclusion DAPT may have a therapeutic value for human tongue carcinoma.Moreover,the effects of DAPT in tumor inhibition may arise partly via the modulation of Notch-1 and Caspase-3. | Brian E. Grottkau Xi-rui Chen Claudia C. Friedrich Xing-mei Yang Wei Jing Yao Wu Xiao-xiao Cai Yu-rong Liu Yuan-ding Huang Yun-feng Lin | 2009 | International Journal of Oral Science2009，1，2： | 7 |
| 2 | 100-Gb/s undersea transmission with high spectral efficiency using pre-filtered QPSK modulation format显示文摘We provide a review of our recent 100-Gb/s, high spectral efficiency (SE) experiment targeting transoceanic and regional undersea transmission distances. We demonstrated that simple pre-filtering at the transmitter together with a maximum a posteriori probability (MAP) detection algorithm can significantly improve SE. We transmitted 96×100-Gb/s pre-filtered polarization division multiplexed return-to-zero quadrature phase shift keyed (PDM-RZ-QPSK) channels with 300% SE over 10608 km using 52-km spans of 150-μm 2 fiber and simple single-stage erbium-doped fiber amplifiers (EDFAs). We also achieved 400% SE over 4368 km using similar techniques. | J.-X. Cai Y. Cai C. R. Davidson D. G. Foursa A. Lucero O. Sinkin W. Patterson A. Pilipetskii G. Mohs Neal S. Bergano | 2010 | Chinese Optics Letters2010，8，9： | 6 |
| 3 | A sperm GPI-anchored protein elicits sperm-cumulus cross-talk leading to the acrosome reaction显示文摘 | Yin, L. Chung, C. M. Huo, R. Liu, H. Zhou, C. Xu, W. Zhu, H. Zhang, J. Shi, Q. Wong, H. Y.C. Chen, J. Lu, Y. Bi, Y. Zhao, C. Du, Y. Ma, M. Cai, Y. Chen, W. Y. Fok, K. L. Tsang, L. L. Li, K. Ni, Y. Chung, Y. W. Zhou, Z. Sha, J. Chan, H. C. | 2009 | 南京医科大学学报(自然科学版)2009，29，4： | 5 |
| 4 | EVOLUTION OF THE ELECTROCHEMICAL CHARACTERISTICS DURING PITTING CORROSION OF PURE ALUMINUM IN SODIUM CHLORIDE SOLUTION显示文摘The corrosion behavior of pure aluminum in neutral 3.0% (mass fraction) sodium chloride (NaCl) solution has been studied using electrochemical impedance spectroscopy (EIS) measurement in conjunction with the scanning electron microscopy (SEM) technique. EIS information on the evolution of pitting corrosion over a period of 15 days has been obtained and analyzed with equivalent circuit technique. The results shown that, during the ensemble constant immersion time, two time constants involved, the high frequency one originated from the protective layer on the corroding surface while the low frequency one from the diffusion process or the corrosion reaction and so on. And there existed a period for oxide film to growth and thickening prior to the commencement of the attacking of chloride ions to the substrate. Meanwhile, good relationship between EIS and the material corrosion type/ severity has been obtained, which has been interpreted according to the characteristics of corrosion process such as auto acceleration of pitting corrosion and the protection of local anodic reaction to the area around them. | Z. Zhang C. Cai F.H. Cao Z.N. Gao J.Q. Zhang C.N. Cao | 2005 | Acta Metallurgica Sinica(English Letters)2005，18，4： | 3 |
| 5 | Megacity impacts on regional ozone formation: observations and WRF-Chem modeling for the MIRAGE-Shanghai field campaign显示文摘 | X. Tie F. Geng A. Guenther J. Cao J. Greenberg R. Zhang E. Apel G. Li A. Weinheimer J. Chen C. Cai | 2013 | Atmospheric Chemistry and Physics2013，，11： | 2 |
| 6 | Regulating the morphology of fluorinated non-fullerene acceptor and polymer donor via binary solvent mixture for high efficiency polymer solar cells显示文摘Fluorinated non-fullerene acceptors(NFAs) usually have planar backbone and a higher tendency to crystallize compared to their non-fluorinated counterparts, which leads to enhanced charge mobility in organic solar cells(OSCs). However, this selforganization behavior may result in excessive phase separation with electron donors and thereby deteriorate device efficiency.Herein, we demonstrate an effective approach to tune the molecular organization of a fluorinated NFA(INPIC-4 F), and its phase separation with the donor PBDB-T, by varying the casting solvent. A prolonged film drying time encourages the crystallization of INPIC-4 F into spherulites and consequently results in excessive phase separation, leading to a low device power conversion efficiency(PCE) of 8.1%. Contrarily, a drying time leads to fine mixed domains with inefficient charge transport properties,resulting in a moderate device PCE of 11.4%. An intermediate film drying time results in the formation of face-on π-π stacked PBDB-T and INPIC-4 F domains with continuous phase-separated networks, which facilitates light absorption, exciton dissociation as well as balanced charge transport towards the electrode, and achieves a remarkable PCE of 13.1%. This work provides a rational guide for optimizing the molecular ordering of NFAs and electron donors for high device efficiency. | Mengxue Chen Zhuohan Zhang Wei Li Jinlong Cai Jiangsheng Yu Emma L. K. Spooner Rachel C. Kilbride Donghui Li Baocai Du Robert S. Gurney Dan Liu Weihua Tang David G. Lidzey Tao Wang | 2019 | Science China Chemistry2019，62，9： | 2 |
| 7 | Sedimentary evidence for changes in the pollution status of Taihu in the Jiangsu region of eastern China显示文摘 | N.L. Rose J.F. Boyle Y. Du C. Yi X. Dai P.G. Appleby H. Bennion S. Cai L. Yu | 2004 | Journal of Paleolimnology2004，，1： | 1 |
| 8 | Optimization of partial constrained layer damping treatment for vibrational energy minimization of vibrating beams显示文摘 | H. Zheng C. Cai X.M. Tan | 2004 | Computers and Structures2004，，29： | 1 |
| 9 | 显示文摘 | P. Song C. Cai M. Skokut B. Kosegi J. Petolino | | 0，2002，： | 1 |
| 10 | Neoadjuvant chemotherapy with gemcitabine/cisplatin vs. methotrexate/vinblastine/doxorubicin/cisplatin for muscle-invasive urothelial carcinoma of the bladder: A retrospective analysis from the University of Southern California显示文摘 | Adrian S. Fairey Siamak Daneshmand David Quinn Tanya Dorff Ryan Dorin Gary Lieskovsky Anne Schuckman Jie Cai Gus Miranda Eila C. Skinner | 2012 | Urologic Oncology: Seminars and Original Investigations2012，，： | 1 |
| 11 | Early Occurrence and Prognostic Significance of p53 Alteration in Primary Carcinoma of the Fallopian Tube显示文摘 | Wenxin Zheng C.James Sung Peiqin Cao Zuo-Feng Zhang Ruya Cai Thomas A. Godwin Elmer E. Kramer Stuart C. Lauchlan | 1997 | Gynecologic Oncology1997，，： | 1 |
| 12 | Design and construction of the BESIII detector显示文摘 | M. Ablikim Z.H. An J.Z. Bai Niklaus Berger J.M. Bian X. Cai G.F. Cao X.X. Cao J.F. Chang C. Chen G. Chen H.C. Chen H.X. Chen J. Chen J.C. Chen L.P. Chen P. Chen X.H. Chen Y.B. Chen M.L. Chen Y.P. Chu X.Z. Cui H.L. Dai Z.Y. Deng M.Y. Dong S.X. Du Z.Z. Du J | 2009 | Nuclear Inst and Methods in Physics Research A2009，，3： | 1 |
| 13 | Cobalt (iron) thiolato complexes containing the Co-ligand phosphine and reaction products of the structural fragment ML 2 L′ (L = 1,2-bidentate thiolate,L′= tertiary phosphine)显示文摘 | Bei-Sheng Kang Zhong-Ning Chen Zhong-Yuan Zhou Han-Qin Liu Han-Rong Gao Bo-Mu Wu Thomas C. W. Mak Yuan-Ba Cai Yong-Jin Xu Zhi-Tao Xu | 1996 | Journal of Cluster Science1996，，3： | 1 |
| 14 | Characterization of colorectal-cancer-related cDNA clones obtained by subtractive hybridization screening显示文摘 | Jiang Cao Xinhan Cai Lei Zheng Liyi Geng Zhengzheng Shi Chia C. Pao Shu Zheng | 1997 | Journal of Cancer Research and Clinical Oncology1997，，8： | 1 |
| 15 | Minimizing vibration response of cylindrical shells through layout optimization of passive constrained layer damping treatments显示文摘 | H. Zheng C. Cai G.S.H. Pau G.R. Liu | 2003 | Journal of Sound and Vibration2003，，3： | 1 |
| 16 | Comments on China’s Tibetan Medicine显示文摘In the field of studies of Tibetan medicine, a voluminous work of 361 pages has been published on nearly all aspects in 2005. No other book or publication can provide such a tremendous amount of information on Tibetan medicine. It has its English edition and other Western language editions. I don’t know of any other books that can provide so many details, so much information and such valuable details as this book by ZHEN Yan and CAI Jing-feng does. They are internationally well-known scientists and specialists, Also I’d like to point out that this book is carefully edited, i.e. the English is of high quality and easy to read and to understand. | ZHEN Yan CAI Jing-feng Jürgen C. Aschoff | 2006 | Chinese Journal of Integrated Traditional and Western Medicine2006，12，2： | 1 |
| 17 | Prediction of cutting force in ball-end milling of sculptured surface using improved Z-map显示文摘 | Z. C. Wei M. J. Wang Y. J. Cai S. F. Wang | 2013 | The International Journal of Advanced Manufacturing Technology . 2013 (5-8)2013，，5： | 1 |
| 18 | Field Behavior of Driven Prestressed High-Strength Concrete Piles in Sandy Soils显示文摘 | Z. X. Yang W. B. Guo F. S. Zha R. J. Jardine C. J. Xu Y. Q. Cai | 2015 | Journal of Geotechnical and Geoenvironmental Engineering2015，，： | 1 |
| 19 | Effects of rice cultivars on methane fluxes in a paddy soil显示文摘 | Z. J. Jia Z. C. Cai H. Xu H. Tsuruta | 2002 | Nutrient Cycling in Agroecosystems2002，，1： | 1 |
| 20 | Transmission of 96x 100-Gb/s bandwidth-constrained PDM-RZ-QPSK channels with 300% spectral efficiency over 10610 km and 400% spectral efficiency over 4370 km显示文摘 | J. -X. Cai Y. Cai C. R. Davidson D.G.Foursa A.J.Lucero O.V.Sinkin W.W.Patterson A.N.Pilipetskii G.Mohs and N.S.Bergano | | 0，，04： | 1 |
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