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| 1 | ZnO薄膜的性能和应用显示文摘1 引言 作为半导体、光导体、压电体和光波导材料的氧化锌(ZnO)在科学和技术上有着广泛的应用。ZnO引人注目的性能包括:晶体结构方面的各向异性;非化学计量缺陷结构;宽的带隙;可分解升华及其两性的化学特性;在可见光区光学透明和相当大的折射率;大的压电常数以及大的声光、电光和非线性光学系数。 | Frans C.M.Van De Pol 陈运祥 | 1991 | 压电与声光1991，13，6： | 9 |
| 2 | In vivo three‐dimensional reconstruction of rat brain axonal projections by diffusion tensor imaging显示文摘 | RongXue Peter C.M.van Zijl Barbara J.Crain MeiyappanSolaiyappan SusumuMori | 1999 | Magn. Reson. Med1999，，： | 1 |
| 3 | 新型水循环之海水冲厕的可持续应用显示文摘水安全日益严重地威胁着全人类的健康和福祉。因此,寻找可持续替代的水资源已成为一个亟待解决的问题。尽管海水淡化和污水回用在一定程度上可以缓解城市的用水紧张,但是这两项技术的高能耗和高费用阻碍了它们的广泛应用。其实,城市用水中20%30%是用于冲洗厕所,经过简单处理后的海水完全可以达到冲厕用水的水质要求。当然海水冲厕和再生水冲厕一样需要配备单独的管道系统。本文通过生命周期评估和敏感性分析方法,在与常规淡水系统进行比较的基础上,系统地研究了海水冲厕、海水淡化以及污水回用这三种替代水资源的方法,在城市水系统中的相对节约淡水的潜力、对环境的影响以及广泛应用的前景。结果表明,海水冲厕具有环境可持续性,其应用主要取决于城市的有效人口密度和距海岸的距离。在有效人口密度超过3000人·km–2及距海岸30 km以内的沿海城市,海水冲厕所带来的总环境影响明显低于其他两个替代水资源。如进一步结合应用适合含盐污水处理的硫酸盐还原、自养反硝化和综合硝化(sulfate reduction,autotrophic denitrification,and nitrification integrated,SANI)处理技术,海水冲厕的潜在应用范围可以扩大到距海岸60 km的沿海城市。对于符合这些要求的沿海城市,建议将海水冲厕纳入城市水系统,从而促进城市水循环的可持续发展。 | 柳晓明 戴吉 吴镝 江峰 陈光浩 徐浩光 Mark C.M.van Loosdrecht | 2016 | Engineering2016，2，4： | 1 |
| 4 | Complex Coacervate Materials as Artificial Cells显示文摘CONSPECTUS:Cells have evolved to be self-sustaining compartmentalized systems that consist of many thousands of biomolecules and metabolites interacting in complex cycles and reaction networks.Numerous subtle intricacies of these self-assembled structures are still largely unknown.The importance of liquid−liquid phase separation(both membraneless and mem-brane bound)is,however,recognized as playing an important role in achieving biological function that is controlled in time and space.Reconstituting biochemical reactions in vitro has been a success of the last decades,for example,establishment of the minimal set of enzymes and nutrients able to replicate cellular activities like the in vitro transcription translation of genes to proteins.Further than this though,artificial cell research has the aim of combining synthetic materials and nonliving macromolecules into ordered assemblies with the ability to carry out more complex and ambitious cell-like functions.These activities can provide insights into fundamental cell processes in simplified and idealized systems but could also have an applied impact in synthetic biology and biotechnology in the future.To date,strategies for the bottom-up fabrication of micrometer scale life-like artificial cells have included stabilized water-in-oil droplets,giant unilamellar vesicles(GUV’s),hydrogels,and complex coacervates.Water-in-oil droplets are a valuable and easy to produce model system for studying cell-like processes;however,the lack of a crowded interior can limit these artificial cells in mimicking life more closely.Similarly membrane stabilized vesicles,such as GUV’s,have the additional membrane feature of cells but still lack a macromolecularly crowded cytoplasm.Hydrogel-based artificial cells have a macromolecularly dense interior(although cross-linked)that better mimics cells,in addition to mechanical properties more similar to the viscoelasticity seen in cells but could be seen as being not dynamic in nature and limiting to the diffusion of biomolecules.On the other hand,liquid−liquid phase separated complex coacervates are an ideal platform for artificial cells as they can most accurately mimic the crowded,viscous,highly charged nature of the eukaryotic cytoplasm.Other important key features that researchers in the field target include stabilizing semipermeable membranes,compartmentalization,information transfer/communication,motility,and metabolism/growth.In this Account,we will briefly cover aspects of coacervation theory and then outline key cases of synthetic coacervate materials used as artificial cells(ranging from polypeptides,modified polysaccharides,polyacrylates,and polymethacrylates,and allyl polymers),finishing with envisioned opportunities and potential applications for coacervate artificial cells moving forward. | Alexander B.Cook Sebastian Novosedlik Jan C.M.van Hest | 2023 | Accounts of Materials Research2023，4，3： | 0 |
| 5 | Surface charging activated mechanism change: A computational study of O, CO, and CO2 interactions on Ag electrodes显示文摘Electrocatalytic and plasma-activated processes receive increasing attention in catalysis. Density functional theory(DFT) calculations are state-of-the-art tools for the fundamental study of reaction mechanisms and predicting the performance of catalytic materials. Proper application of DFT-based methods is crucial when investigating charge-doped electrode surfaces during electrocatalytic and plasma-activated reactions. Here, as a model electrode for plasma-activated CO2 splitting, we studied the interactions of O, CO, and CO2 with the neutral and progressively charged Ag(111) metal surfaces. We show that the application of correction procedures is necessary to obtain accurate adsorption energy profiles of O atoms,CO and CO2 molecules on Ag surfaces that are under the influence of additional electrons. Interestingly,the oxidation of CO is found to shift from a Langmuir–Hinshelwood mechanism on a neutral electrode to an Eley–Rideal mechanism on charged electrodes. Furthermore, we show that the surface charging of Ag(111) electrodes increase their CO2 reduction performance by enhancing the adsorption of O atoms and desorption of CO molecules. A further increase in the absolute charge-state of the electrode surface is expected to waive the thermodynamic barriers for the CO2 splitting reaction. | Ilker Tezsevin Mauritius C.M.van de Sanden Suleyman Er | 2020 | Journal of Energy Chemistry2020，29，11： | 0 |
| 6 | Design and thermodynamic analysis of a pathway enabling anaerobic production of poly-3-hydroxybutyrate in Escherichia coli显示文摘Utilizing anaerobic metabolisms for the production of biotechnologically relevant products presents potential advantages,such as increased yields and reduced energy dissipation.However,lower energy dissipation may indicate that certain reactions are operating closer to their thermodynamic equilibrium.While stoichiometric analyses and genetic modifications are frequently employed in metabolic engineering,the use of thermodynamic tools to evaluate the feasibility of planned interventions is less documented.In this study,we propose a novel metabolic engineering strategy to achieve an efficient anaerobic production of poly-(R)-3-hydroxybutyrate(PHB)in the model organism Escherichia coli.Our approach involves re-routing of two-thirds of the glycolytic flux through non-oxidative glycolysis and coupling PHB synthesis with NADH re-oxidation.We complemented our stoichiometric analysis with various thermodynamic approaches to assess the feasibility and the bottlenecks in the proposed engineered pathway.According to our calculations,the main thermodynamic bottleneck are the reactions catalyzed by the acetoacetyl-CoAβ-ketothiolase(EC 2.3.1.9)and the acetoacetyl-CoA reductase(EC 1.1.1.36).Furthermore,we calculated thermodynamically consistent sets of kinetic parameters to determine the enzyme amounts required for sustaining the conversion fluxes.In the case of the engineered conversion route,the protein pool necessary to sustain the desired fluxes could account for 20%of the whole cell dry weight. | Karel Olavarria Marco V.Becker Diana Z.Sousa Mark C.M.van Loosdrecht S.Aljoscha Wahl | 2023 | Synthetic and Systems Biotechnology2023，8，4： | 0 |
| 7 | Amphiphilic AIEgen-polymer aggregates:Design,self-assembly and biomedical applications显示文摘Aggregation-induced emission(AIE)is a phenomenon in which fluorescence is enhanced rather than quenched upon molecular assembly.AIE fluorogens(AIEgens)are flexible,conjugated systems that are limited in their dynamics when assembled,which improves their fluorescent properties.This intriguing feature has been incorporated in many different molecular assemblies and has been extended to nanoparticles composed of amphiphilic polymer building blocks.The integration of the fascinating AIE design principle with versatile polymer chemistry opens up new frontiers to approach and solve intrinsic obstacles of conventional fluorescent materials in nanoscience,including the aggregation-caused quenching effect.Furthermore,this integration has drawn significant attention from the nanomedicine community,due to the additional advantages of nanoparticles comprising AIEgenic molecules,such as emission brightness and fluorescence stability.In this regard,a range of AIEgenic amphiphilic polymers have been developed,displaying enhanced emission in the self-assembly/aggregated state.AIEgenic assemblies are regarded as attractive nanomaterials with inherent fluorescence,which display promising features in a biomedical context,for instance in biosensing,cell/tissue imaging and tracking,as well as(photo)therapeutics.In this review,we describe recent strategies for the design and synthesis of novel types of AIEgenic amphiphilic polymers via facile approaches including direct conjugation to natural/synthetic polymers,polymerization,post-polymerization and supramolecular host−guest interactions.Their self-assembly behavior and biomedical potential will be discussed. | Shoupeng Cao Jingxin Shao Loai K.E.A.Abdelmohsen Jan C.M.van Hest | 2022 | Aggregate2022，3，1： | 0 |
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