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| 1 | Cell membrane-covered nanoparticles as biomaterials显示文摘Surface engineering of synthetic carriers is an essential and important strategy for drug delivery in vivo.However,exogenous properties make synthetic nanosystems invaders that easily trigger the passive immune clearance mechanism,increasing the retention effect caused by the reticuloendothelial systems and bioadhesion,finally leading to low therapeutic efficacy and toxic effects.Recently,a cell membrane cloaking technique has been reported as a novel interfacing approach from the biological/immunological perspective,and has proved useful for improving the performance of synthetic nanocarriers in vivo.After cell membrane cloaking,nanoparticles not only acquire the physiochemical properties of natural cell membranes but also inherit unique biological functions due to the presence of membrane-anchored proteins,antigens,and immunological moieties.The derived biological properties and functions,such as immunosuppressive capability,long circulation time,and targeted recognition integrated in synthetic nanosystems,have enhanced their potential in biomedicine in the future.Here,we review the cell membrane-covered nanosystems,highlight their novelty,introduce relevant biomedical applications,and describe the future prospects for the use of this novel biomimetic system constructed from a combination of cell membranes and synthetic nanomaterials. | Mingjun Xuan Jingxin Shao Junbai Li | 2019 | National Science Review2019，6，3： | 9 |
| 2 | Near-infrared light-driven Janus capsule motors: Fabrication, propulsion, and simulation显示文摘我们报导一没有燃料,在红外线附近(NIR ) 驾驶 Janus microcapsule 马达。Janus microcapsule 马达被帮助模板的聚合电解质 layer-by-layer 汇编制作,由在一个方面上金层喷洒列在后面。NIR 动力的 Janus 马达以 42 /DLHC 的最大的速度完成了高推进合成交付一个高特定的能力(930 mAed nanoparticles,有 81.8% 的轻发射度和 118.62ichia coli 的一个水接触角度(E。coli ) ,肠球菌(ENT ) 和全部的大肠菌(TC ) 被分析。除了 EC 和没有 3, ,结果揭示了低 concentrati 吗?? | Yingjie Wu Tieyan Si Jingxin Shao Zhiguang Wu Qiang He | 2016 | Nano Research2016，9，12： | 6 |
| 3 | Perspective of energy transfer from light energy into biological energy显示文摘Energy has always been the most concerned topic in the world due to the large consumption. Various types of energy have been exploited and developed to enhance the output amount so that high requirements can be met. Like the hydro-energy, wind energy, and tidal energy, light energy as a renewable, clean, and widespread energy can be easily harvested. In microcosmic scale, some specific proteins and enzymes in green plants and bacteria play an important role in light harvest and energy conversion via photosynthesis. Inspired by the biomimetic sparks,these bioactive macromolecules and some artificially synthetic unites have been integrated together to improve the light-harvesting, and enhance their utilization efficiency. In this feature article, we primarily discuss that how to create the bio-inorganic hybrid energy converted system via biomimetic assembly strategy and artificially achieve the transformation from light into bioenergy, meanwhile highlight some promising works. | Mingjun Xuan Jie Zhao Jingxin Shao Qi Li Junbai Li | 2017 | Green Energy & Environment2017，2，1： | 2 |
| 4 | Dual targeting of mTORC1/C2 complexes enhances histone deacetylase inhibitor-mediated anti-tumor efficacy in primary HCC cancer in vitro and in vivo显示文摘 | Huanjie Shao Chun Gao Haikuo Tang Hao Zhang Lewis R. Roberts Bonnie L. Hylander Elizabeth A. Repasky Wen W. Ma Jingxin Qiu Alex A. Adjei Grace K. Dy Chunrong Yu | 2011 | Journal of Hepatology2011，，1： | 2 |
| 5 | Dual targeting of mTORC1/C2 complexes enhances histone deacetylase inhibitor-mediated anti-tumor efficacy in primary HCC cancer in vitro and in vivo显示文摘 | Huanjie Shao Chun Gao Haikuo Tang Hao Zhang Lewis R. Roberts Bonnie L. Hylander Elizabeth A. Repasky Wen W. Ma Jingxin Qiu Alex A. Adjei Grace K. Dy Chunrong Yu | 2011 | Journal of Hepatology2011，，1： | 1 |
| 6 | SLC34A2 Gene mutation of pulmonary alveolar microlithiasis: Report of four cases and review of literatures显示文摘 | Xinzhen Yin Huiying Wang Dingwen Wu Guohua Zhao Jingxin Shao Yu Dai | 2012 | Respiratory Medicine2012，，： | 1 |
| 7 | Morphology and structure of electrospun mats from regenetated silk fibroin aqueous solutions with adjusting pH 显示文摘 | Zhu Jingxin Shao Huili Hu Xuechao | 2007 | Biological Maeromolecules2007，，41： | 1 |
| 8 | Towards Task-Free Privacy-Preserving Data Collection显示文摘With the rapid developments of Internet of Things(IoT)and proliferation of embedded devices,large volume of personal data are collected,which however,might carry massive private information about attributes that users do not want to share.Many privacy-preserving methods have been proposed to prevent privacy leakage by perturbing raw data or extracting task-oriented features at local devices.Unfortunately,they would suffer from significant privacy leakage and accuracy drop when applied to other tasks as they are designed and optimized for predefined tasks.In this paper,we propose a novel task-free privacy-preserving data collection method via adversarial representation learning,called TF-ARL,to protect private attributes specified by users while maintaining data utility for unknown downstream tasks.To this end,we first propose a privacy adversarial learning mechanism(PAL)to protect private attributes by optimizing the feature extractor to maximize the adversary’s prediction uncertainty on private attributes,and then design a conditional decoding mechanism(ConDec)to maintain data utility for downstream tasks by minimizing the conditional reconstruction error from the sanitized features.With the joint learning of PAL and ConDec,we can learn a privacy-aware feature extractor where the sanitized features maintain the discriminative information except privacy.Extensive experimental results on real-world datasets demonstrate the effectiveness of TF-ARL. | Zhibo Wang Wei Yuan Xiaoyi Pang Jingxin Li Huajie Shao | 2022 | China Communications2022，19，7： | 0 |
| 9 | Amphiphilic AIEgen-polymer aggregates:Design,self-assembly and biomedical applications显示文摘Aggregation-induced emission(AIE)is a phenomenon in which fluorescence is enhanced rather than quenched upon molecular assembly.AIE fluorogens(AIEgens)are flexible,conjugated systems that are limited in their dynamics when assembled,which improves their fluorescent properties.This intriguing feature has been incorporated in many different molecular assemblies and has been extended to nanoparticles composed of amphiphilic polymer building blocks.The integration of the fascinating AIE design principle with versatile polymer chemistry opens up new frontiers to approach and solve intrinsic obstacles of conventional fluorescent materials in nanoscience,including the aggregation-caused quenching effect.Furthermore,this integration has drawn significant attention from the nanomedicine community,due to the additional advantages of nanoparticles comprising AIEgenic molecules,such as emission brightness and fluorescence stability.In this regard,a range of AIEgenic amphiphilic polymers have been developed,displaying enhanced emission in the self-assembly/aggregated state.AIEgenic assemblies are regarded as attractive nanomaterials with inherent fluorescence,which display promising features in a biomedical context,for instance in biosensing,cell/tissue imaging and tracking,as well as(photo)therapeutics.In this review,we describe recent strategies for the design and synthesis of novel types of AIEgenic amphiphilic polymers via facile approaches including direct conjugation to natural/synthetic polymers,polymerization,post-polymerization and supramolecular host−guest interactions.Their self-assembly behavior and biomedical potential will be discussed. | Shoupeng Cao Jingxin Shao Loai K.E.A.Abdelmohsen Jan C.M.van Hest | 2022 | Aggregate2022，3，1： | 0 |
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