| 1 | Functionalized metal-organic frameworks with strong acidity and hydrophobicity as an efficient catalyst for the production of 5-hydroxymethylfurfural显示文摘In the dehydration of fructose to 5-hydroxymethyl furfural(HMF),in situ produced water weakens the acid strength of the catalyst and causes the rehydration of HMF,causing unsatisfactory catalytic activity and selectivity.In this work,a class of benzenesulfonic acid-grafted metal-organic frameworks with strong acidity and hydrophobicity is obtained by the direct sulfonation method using 4-chlorobenzenesulfonic acid as sulfonating agent.The resultant MOFs have a specific surface area of greater than 250 m^(2)·g^(-1),acid density above 1.0 mmol·g^(-1),and water contact angle up to 129°.The hydrophobic MOF-PhSO_(3)H exhibits both higher catalytic activity and selectivity than MOF-SO_(3)H in the HMF synthesis due to its better hydrophobicity and olephilicity.Moreover,the catalyst has a high recycled stability.At last,fructose is completely converted,and 98.0%yield of HMF is obtained under 120℃ in a DMSO solvent system.The successful preparation of the hydrophobic acidic MOF provides a novel hydrophobic catalyst for the synthesis of HMF. | Huan Li Yao Zhong Luxi Wang Qiang Deng Jun Wang Zheling Zeng Xinxiang Cao Shuguang Deng | 2021 | Chinese Journal of Chemical Engineering2021，34，5： | 2 |
| 2 | Efficacy of acupuncture on repair of glial scars in rats with traumatic brain injury显示文摘OBJECTIVE:To explore the underlying mechanism of acupuncture on nerve repair by investigating its effect on the differentiation of glial cells and the repair of glial scars.METHODS:Sprague-Dawley rats were randomly allocated to three groups:normal group,model group,and acupuncture group.Acupuncture was applied at Renzhong(GV26),Baihui(GV20),Fengfu(GV16),Yamen(GV15)and Hegu(LI4)within 12 h after TBI modeling with a frequency of one session per day for 4 weeks.Neurobehavioral assessment,hematoxylin and eosin staining,immunofluorescence detection,and magnetic resonance imaging scanning were performed on days 3,7,14,and 28 after modeling of traumatic brain injury(TBI).RESULTS:Acupuncture promoted the proliferation of glial cells and glial scars at an early stage but inhibited the proliferation of glial cells and glial scars at a late stage.Morphological observations and immunofluorescence histochemistry showed that the morphology of the perilesional cortex in the acupuncture group was improved and the number of neurons was increased when compared with the model group.The lesion size of ipsilateral brain parenchyma in the acupuncture group was smaller than in the model group on days 7,14,and 28(P<0.05)after TBI modeling.CONCLUSIONS:Acupuncture might have a bidirectional regulatory effect on glial scar repair after TBI by promoting the proliferation of glial cells and glial scars to limit the injured area and relieve nerve injury during the early stages,and by inhibiting glial scar hyperplasia to benefit the regeneration and repair of neurons and axons and promote neurological function recovery during the later stages. | ZENG Hai CAO Luxi PANG Zhao ZHAO Sisi WANG Shiqi LIN Zhuowen CHEN Minan LIN Shujun ZHANG Yimin | 2023 | Journal of Traditional Chinese Medicine2023，43，2： | 0 |
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