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| 1 | The vital threat of an upper gastrointestinal bleeding: Risk factor analysis of 121 consecutive patients显示文摘瞄准:在预言死亡的病人风险由于分析重要性上面胃肠(UGI ) 在今天的治疗学的政体下面流血。方法:从 1998 ~ 2001,有 UGI 流血的诊断的 121 个病人在我们的医院里被对待。基于病人的数据,一回顾多变量数据分析与开始,超过 270 个单个因素被执行。随后,下列潜在的风险因素经历了逻辑回归分析:年龄,性,起始的血红素, coumarines ,肝肝硬化,前凝血酶时间(磅),胃溃疡(小弯曲),十二指肠溃疡(灯泡我们背墙),福雷斯特分类,脉管的树桩, variceal 流血, Mallory-Weiss 症候群, RBC 替换,周期性的流血,保守、外科的治疗。结果:七十男性(58%) 和 51 女性(42%) 有 70 的中部的年龄的病人(变化:21-96 ) 年被对待。他们的在里面医院死亡是 14% 。当(11/91 )12% 在保守治疗以后死于病人时,(6/30 )20% 在经历外科的治疗以后死了。流血的 UGI 由于十二指肠溃疡发生了(n = 36;30%) ,胃溃疡(n = 35;29%) ,食道的静脉曲张病(n = 12;10%) , Mallory-Weiss 症候群(n = 8;7%) ,粘膜的腐蚀损害(n = 20;17%) ,癌症(n = 5;4%) , coagulopathy (n = 4;3%) ,淋巴瘤(n = 2;2%) ,良性瘤(n = 2;2%) 并且未知理智(n = 1;1%) 。所有上述的因素的逻辑回归分析揭示了那肝肝硬化和十二指肠溃疡(灯泡我们背墙) 是为在 UGI 流血以后的一堂致命的功课的联系风险因素。在内视镜检查法以前,仅仅肝肝硬化是一个可估价的风险因素。此后,肝肝硬化,流血溃疡的地点(灯泡我们背墙) 并且病人的性(男性) 具有为有流血溃疡的病人的临床的结果(死亡) 的预示的重要性。结论:在今天的临床的常规使用的最预示的参数不在预言一个病人的重要威胁由流血的 UGI 摆姿势是足够可靠的。在另一方面,肝肝硬化更经常显著地与增加的风险被联系在在以后的十二指肠的墙定位的溃疡流血以后死。 | Peter Schemmer Frank Decker Genevieve Dei-Anane Volkmar Henschel Klaus Buhl Christian Herfarth Stefan Riedl | 2006 | World Journal of Gastroenterology2006，12，22： | 16 |
| 2 | Metabolic activity of Streptococcus mutans biofilms and gene expression during exposure to xylitol and sucrose显示文摘The objective of the study was to analyse Streptococcus mutans biofilms grown under different dietary conditions by using multifaceted methodological approaches to gain deeper insight into the cariogenic impact of carbohydrates. S. mutans biofilms were generated during a period of 24 h in the following media: Schaedler broth as a control medium containing endogenous glucose, Schaedler broth with an additional 5% sucrose, and Schaedler broth supplemented with 1% xylitol. The confocal laser scanning microscopy(CLSM)-based analyses of the microbial vitality, respiratory activity(5-cyano-2,3-ditolyl tetrazolium chloride, CTC) and production of extracellular polysaccharides(EPS) were performed separately in the inner, middle and outer biofilm layers. In addition to the microbiological sample testing, the glucose/sucrose consumption of the biofilm bacteria was quantified, and the expression of glucosyltransferases and other biofilm-associated genes was investigated. Xylitol exposure did not inhibit the viability of S. mutans biofilms, as monitored by the following experimental parameters: culture growth, vitality, CTC activity and EPS production. However,xylitol exposure caused a difference in gene expression compared to the control. Gtf C was upregulated only in the presence of xylitol.Under xylitol exposure, gtf B was upregulated by a factor of 6, while under sucrose exposure, it was upregulated by a factor of three.Compared with glucose and xylitol, sucrose increased cell vitality in all biofilm layers. In all nutrient media, the intrinsic glucose was almost completely consumed by the cells of the S. mutans biofilm within 24 h. After 24 h of biofilm formation, the multiparametric measurements showed that xylitol in the presence of glucose caused predominantly genotypic differences but did not induce metabolic differences compared to the control. Thus, the availability of dietary carbohydrates in either a pure or combined form seems to affect the cariogenic potential of S. mutans biofilms. | Eva-Maria Decker Christian Klein Dimitri Schwindt Christiane von Ohle | 2014 | International Journal of Oral Science2014，6，4： | 4 |
| 3 | FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer (FIRE-3): a randomised, open-label, phase 3 trial显示文摘 | Volker Heinemann Ludwig Fischer von Weikersthal Thomas Decker Alexander Kiani Ursula Vehling-Kaiser Salah-Eddin Al-Batran Tobias Heintges Christian Lerchenmüller Christoph Kahl Gernot Seipelt Frank Kullmann Martina Stauch Werner Scheithauer J?rg Hielscher | 2014 | Lancet Oncology2014，，10： | 2 |
| 4 | UV- curing chemistry: past, present, and future 显示文摘 | Decker Christian | 1987 | Journal of Coatings Technology1987，59，751： | 1 |
| 5 | Synthesis of nanocomposite polymers by UV-radiation curing显示文摘 | Christian Decker Laurent Keller Khalid Zahouily | 2005 | Polymer2005，，46： | 1 |
| 6 | UV-curing chemistry:past,present,and future显示文摘 | Christian | 1987 | Journal of Coatings Technology1987，59，751： | 1 |
| 7 | Overcoming oxygen inhibition in UV-curing of acrylate coatings by carbon dioxide inerting,Part Ⅰ显示文摘 | Katia Studer Christian Decker Erich Beckb | 2003 | Progress in Organic Coatings2003，48，： | 1 |
| 8 | Overcoming oxygen inhibition in UV-curing of acrylate coatings by carbon dioxide inerting : Part Ⅰ显示文摘 | Katia Studer Christian Decker Erich Beck | 2003 | Progress in Organic Coatings2003，48，1： | 1 |
| 9 | Combined NGS Approaches Identify Mutations in the Intraflagellar Transport Gene IFT140 in Skeletal Ciliopathies with Early Progressive Kidney Disease显示文摘 | Miriam Schmidts Valeska Frank Tobias Eisenberger Saeed al Turki Albane A. Bizet Dinu Antony Suzanne Rix Christian Decker Nadine Bachmann Martin Bald Tobias Vinke Burkhard Toenshoff Natalia Di Donato Theresa Neuhann Jane L. Hartley Eamonn R. Maher Radovan | 2013 | Human Mutation2013，，5： | 1 |
| 10 | PTHR1 Loss-of-Function Mutations in Familial, Nonsyndromic Primary Failure of Tooth Eruption显示文摘 | Eva Decker Angelika Stellzig-Eisenhauer Britta S. Fiebig Christiane Rau Wolfram Kress Kathrin Saar Franz Rüschendorf Norbert Hubner Tiemo Grimm Bernhard H.F. Weber | 2008 | The American Journal of Human Genetics2008，，6： | 1 |
| 11 | Synthesis ofnanocomposite polymers by UV-radiation curing 显示文摘 | Christian Decker Laurent Keller Khalid Zahouily | 2005 | Polymer2005，46，： | 1 |
| 12 | Overcoming oxygen inhibition in UV-curing of acrylate coatings by carbon dioxide inerting: Part II显示文摘 | Katia Studer Christian Decker Erich Beck Reinhold Schwalm | 2003 | Progress in Organic Coatings2003，，1： | 1 |
| 13 | A Location Model for Communicating and Processing of Context显示文摘 | MICHAEL BEIG TOBIAS ZIMMER CHRISTIAN DECKER | 2002 | Personal and Ubiquitous Computing2002，，6： | 1 |
| 14 | Cost-Ben-efit Model for Smart Items in The Supply Chain显示文摘 | Christian Decker Martin Berchtold Leonardo Weiss F | 2009 | Communica-tions of the Association for Information Systems2009，，5： | 1 |
| 15 | Tomac-real - time Message Ordering in Wireless Sensor Networks Using the MAC Layer显示文摘 | Albert Krohn Michael Beigl Christian Decker | 2005 | In Proceedings of the 2nd International Workshop on Networked Sensing Systems (INSS)2005，，： | 1 |
| 16 | Muhistream mixing head with unique twin filler dosing system for hot cast elastomers显示文摘 | Decker Christian Dormann Bjoem | 2010 | Rubber World2010，243，1： | 1 |
| 17 | Association of Low Striatal Dopamine D^sub 2^ Receptor Availability With Nicotine Dependence Similar to That Seen With Other Drugs of Abuse显示文摘 | Fehr Christoph Yakushev Igor Hohmann Nina Buchholz Hans-Georg Landvogt Christian Deckers Hanna Eberhardt Alexandra Kl?ger Marie Smolka Michael N Scheurich Armin Dielentheis Thomas Schmidt Lutz G R?sch Frank Bartenstein Peter Gründer Gerhard | 2008 | The American Journal of Psychiatry2008，，4： | 1 |
| 18 | Photostabilization of poly (vinyl chloride)by protective coatings显示文摘 | Decker Christian | 2001 | Journal of Vinyl and Additive Technology2001，7，4： | 1 |
| 19 | Overcoming oxygen inhibition in UV-curing of acrylate coatings by carbon dioxide inerting: Part I 显示文摘 | Katia Studer Christian Decker Erich Beck | 2003 | Progress in Organic Coatings2003，48，1： | 1 |
| 20 | Overcoming oxygen inhibition in UV curing of acrylate coatings by carbon dioxide inerting: Part Ⅱ 显示文摘 | Katia SIuder Christian Decker Erich Beckb | 2003 | Progress in Organic Coatings2003，48，1： | 1 |
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