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| 1 | Prevalence of Helicobacter pylori infection and intestinal metaplasia in subjects who had undergone surgery for gastric adenocarcinoma in Northwest Italy显示文摘AIM: To investigate the seroprevalence of Helicobacter pylori(H pylorri) infection and its more virulent strains as well as the correlation with the histologic features among patients who had undergone surgery for gastric cancer (GC).METHODS: Samples from 317 (184 males, 133females, mean age 69±3.4 years) consecutive patients who had undergone surgery for gastric non-cardia adenocarcinoma were included in the study. Five hundred and fifty-five (294 males, 261 females, mean age 57.3±4.1 years) patients consecutively admitted to the Emergency Care Unit served as control. Histological examination of tumor, lymph nodes and other tissues obtained at the time of surgery represented the diagnostic 'gold standard'. An enzyme immunosorbent assay was used to detect serum anti-H pylori(IgG)antibodies and Western blotting technique was utilized to search for anti-CagA protein (IgG).RESULTS: Two hundred and sixty-one of three hundred and seventeen (82.3%) GC patients and 314/555 (56.5%)controls were seropositive for anti-H pylori (P<0.0001;OR, 3.58; 95%CI, 2.53-5.07). Out of the 317 cases, 267(84.2%) were seropositive for anti-CagA antibody vs 100 out of 555 (18%) controls (P<0.0001; OR, 24.30;95%CI, 16.5-35.9). There was no difference between the frequency of H pyloriin intestinal type carcinoma (76.2%) and diffuse type cancer (78.8%). Intestinal metaplasia (IM) was more frequent but not significant in the intestinal type cancer (83.4% vs 75.2% in diffuse type and 72.5% in mixed type). Among the patients examined for IM, 39.8% had IM type Ⅰ, 8.3% type Ⅱ and 51.9% type Ⅲ (type Ⅲ vs others, P = 0.4).CONCLUSION; This study confirms a high seroprevalence of H pyloriinfection in patients suffering from gastric adenocarcinoma and provides further evidence that searching for CagA status over H pylori infection might confer additional benefit in identifying populations at greater risk for this tumor. | Giorgio Palestro Rinaldo Pellicano Gian Ruggero Fronda Guido Valente Marco De Giuli Tito Soldati Agostino Pugliese Stefano Taraglio Mauro Garino Donata Campra Miguel Angel Cutufia Elena Margaria Giancarlo Spinzi Aldo Ferrara Giorgio Marenco Mario Rizzetto Antonio Ponzetto | 2005 | World Journal of Gastroenterology2005，11，45： | 5 |
| 2 | Italian consensus guidelines for chronic pancreatitis显示文摘 | Luca Frulloni Massimo Falconi Armando Gabbrielli Ezio Gaia Rossella Graziani Raffaele Pezzilli Generoso Uomo Angelo Andriulli Gianpaolo Balzano Luigi Benini Lucia Calculli Donata Campra Gabriele Capurso Giulia Martina Cavestro Claudio De Angelis Luigi Ghe | 2010 | Digestive and Liver Disease2010，，： | 1 |
| 3 | Italian consensus guidelines for chronic pancreatitis显示文摘 | Luca Frulloni Massimo Falconi Armando Gabbrielli Ezio Gaia Rossella Graziani Raffaele Pezzilli Generoso Uomo Angelo Andriulli Gianpaolo Balzano Luigi Benini Lucia Calculli Donata Campra Gabriele Capurso Giulia Martina Cavestro Claudio De Angelis Luigi Ghe | 2010 | Digestive and Liver Disease2010，，： | 1 |
| 4 | High-Performance liquid chromatographic purification of γ-linolenic acid(GLA)from the seed oil of two boraginaceae species显示文摘 | P Campra J L | 2002 | Chromatographia2002，56，： | 1 |
| 5 | Utility and limitations of splanchnic venous ultrasonography in diagnosis of portal hypertension显示文摘 | Rector WG Jr Campra J Rails PW | 1986 | J Clin Ultrasound1986，14，12： | 1 |
| 6 | α-Linolenic acid purification from seed oil sources by argentated silia gel chromatography colunn 显示文摘 | Guil Gerrero J L Campra Madrid C Hassan Belarbi E L | 2000 | Process Biochemi- stry2000，36，： | 1 |
| 7 | T - Linolenic acid purification from seed oil sources by argentated silica gel chromatography colum 显示文摘 | GUIL- GUERRERO J L CAMPRA - MADRID P BE- LARBI P H | 2000 | Process Biochemistry2000，36，1： | 1 |
| 8 | Serum heat shock protein 27 levels in patients with hepatocellular carcinoma显示文摘 | Gabriella Gruden Patrizia Carucci Valentina Lolli Loretta Cosso Erika Dellavalle Emanuela Rolle Alessandro Cantamessa Silvia Pinach Maria Lorena Abate Donata Campra Franco Brunello Graziella Bruno Mario Rizzetto Paolo Cavallo Perin | 2013 | Cell Stress and Chaperones2013，，2： | 1 |
| 9 | Surface temperature cooling trends and negative radiative forcing due to land use change toward greenhouse farming in southeastern Spain显示文摘 | Campra P Garcia M Canton Y | 2008 | Journal of Geophysical Research:Atmospheres2008，113，18： | 1 |
| 10 | Italian consensus guidelines for chronic pancreatitis显示文摘 | Luca Frulloni Massimo Falconi Armando Gabbrielli Ezio Gaia Rossella Graziani Raffaele Pezzilli Generoso Uomo Angelo Andriulli Gianpaolo Balzano Luigi Benini Lucia Calculli Donata Campra Gabriele Capurso Giulia Martina Cavestro Claudio De Angelis Luigi Ghe | 2010 | Digestive and Liver Disease2010，，： | 1 |
| 11 | Sur- face temperature cooling trends and negative radiative forcing due to land use change toward greenhouse farming in southeastern Spain显示文摘 | CAMPRA P GARCIA M CANTON Y | 2008 | Journal of Geophysi- cal Research2008，113，18109： | 1 |
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