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| 1 | Identical Penicillin- Binding Domains in Penicillin-Binding Proteins of Streptococcus pneumoniae Clinical Isolates with Different Levels of 13-Lactam Resistance 显示文摘 | Chesnel L Carapito R Croiz6 J | 2005 | Antimicrob Agents Chemother2005，49，： | 1 |
| 2 | Electron transfer dissociation in conjunction with collision activation to investi- gate the Drosophila melanogaster phosphoproteome显示文摘 | Domon B Bodenmiller B Carapito C | 2009 | J Pro- teome Res2009，8，6： | 1 |
| 3 | Identical penicillin-bind- ing domains in penicillin-binding proteins of Streptococcus pneu- moniae clinical isolates with different levels of beta-lactam resist- ance显示文摘 | Chesnel L Carapito R Croize J | 2005 | Antimicrob Agents Cbemother2005，49，7： | 1 |
| 4 | Common altera- tions in PBPla from resistant streptococcus pneumoniae de- crease its reactivity towards betmlactams: structural insights 显示文摘 | JOB V CARAPITO R VEMET T | 2008 | JBiolChem2008，283，8： | 1 |
| 5 | MSDA,a proteomics software suite for in-depth mass spectrometry data analysis using grid computing显示文摘 | CARAPITO C BUREL A GUTERL P | 2014 | Proteomics2014，14，9： | 1 |
| 6 | Detection of prion protein in urine-derived injectable fertility products by a targeted proteomic approach显示文摘 | Van Dorsselaer A Carapito C Delalande F | 2011 | PLoS One2011，6，17： | 1 |
| 7 | Proteomic analysis of grapevine tissues subjected to herbicide stress 显示文摘 | Antonio J Castrol Christine Carapito Nathalie Zorn | 2005 | Journal of Experimental Botany2005，56，421： | 1 |
| 8 | Efficient hydrolysis of hemicellulose by a Fusarium graminearum xylanase blend produced at high levels in Escherichia coli显示文摘 | Carapito R Carapito C Jeltsch JM | | 0，，02： | 1 |
| 9 | Genetics, genomics, and evolutionary biol- ogy of NKG2D ligands显示文摘 | Carapito R Bahrain S | 2015 | Immunol Rev2015，267，1： | 1 |
| 10 | Pro- teome analysis of plant-virus interactome: Comprehensive data for virus multiplication inside their hosts 显示文摘 | BRIZARD j P CARAPITO C DELALANDE F | 2006 | Mol Cell Pro- teomics2006，5，： | 1 |
| 11 | Identical penicillin-bind-ing domains in penicillin-binding proteins of Streptococcus pneu-moniae clinical isolates with different levels of beta-lactam resist-ance显示文摘 | Chesnel L Carapito R Croiz6 J | 2005 | Antimicrob Agents Chemother2005，49，7： | 1 |
| 12 | Identical penicillin -binding domains in penicillin - binding proteins of Streptococcus pneumoniae clinical isolates with different levels of β-lactam resistance显示文摘 | Chesnel L Carapito R Croize J | 2005 | Antimicrob Agents Chemother2005，49，7： | 1 |
| 13 | Common alterations in PBP1 a from resistant streptococcus pneumoniae decrease its reactivity towards beta - lactams : Structural insights 显示文摘 | Job V Carapito R Vernet T | 2008 | J Biol Chem2008，283，8： | 1 |
| 14 | Diversity of the exoproteome of Fusarium graminearum grown on plant cell wall显示文摘 | Phalip V Delalande F Carapito C | 2005 | Current Genetics2005，48，： | 1 |
| 15 | Pneumococcal beta - lactam resistance due to a conformational change in penicillin - binding protein 2x显示文摘 | Carapito R Chesnel L Vernet T | 2006 | J Biol Chem2006，281，3： | 1 |
| 16 | Detection of prion protein in urine-derived injectable fertility products by a targeted proteomic approach显示文摘 | Van Dorsselaer A Carapito C Delalande F Schaeffer-Reiss C Thierse D Diemer H McNair D S Krewski D Cashman N R | | 0，，03： | 1 |
| 17 | Efficient hydrolysis of hemicellulose by a Fusarium graminearum xylanase blend produced at high levels in Escherichia coil显示文摘 | CARAPITO C | 2008 | Bioresource Technology2008，100，2009： | 1 |
| 18 | Host cell protein quantification workflow using optimized standards combined with data-independent acquisition mass spectrometry显示文摘Monitoring of host cell proteins(HCPs)during the manufacturing of monoclonal antibodies(mAb)has become a critical requirement to provide effective and safe drug products.Enzyme-linked immunosorbent assays are still the gold standard methods for the quantification of protein impurities.However,this technique has several limitations and does,among others,not enable the precise identification of proteins.In this context,mass spectrometry(MS)became an alternative and orthogonal method that delivers qualitative and quantitative information on all identified HCPs.However,in order to be routinely implemented in biopharmaceutical companies,liquid chromatography-MS based methods still need to be standardized to provide highest sensitivity and robust and accurate quantification.Here,we present a promising MS-based analytical workflow coupling the use of an innovative quantification standard,the HCP Profiler solution,with a spectral library-based data-independent acquisition(DIA)method and strict data validation criteria.The performances of the HCP Profiler solution were compared to more conventional standard protein spikes and the DIA approach was benchmarked against a classical datadependent acquisition on a series of samples produced at various stages of the manufacturing process.While we also explored spectral library-free DIA interpretation,the spectral library-based approach still showed highest accuracy and reproducibility(coefficients of variation<10%)with a sensitivity down to the sub-ng/mg mAb level.Thus,this workflow is today mature to be used as a robust and straightforward method to support mAb manufacturing process developments and drug products quality control. | Steve Hessmann Cyrille Chery Anne-Sophie Sikora Annick Gervais Christine Carapito | 2023 | Journal of Pharmaceutical Analysis2023，13，5： | 0 |
| 19 | Advances in Research on COVID-19 Vaccination for People Living with HIV显示文摘Introduction In December 2019,multiple cases of aggravated pneumonia of unidentified origin were reported inWuhan,China.These were confirmed to be caused by a novel coronavirus.The World Health Organization(WHO)named the disease coronavirus disease 2019(COVID-19).The International Committee on Taxonomy of Viruses officially identified the novel virus severe acute respiratory syndrome coronavirus 2(SARSCoV-2).[1]Although China is now a low endemic areawith a downward trend in the number of confirmed and suspected cases,[2]the threat of the COVID-19 pandemic remains critical.By mid-March 2022,the cumulative number of reported confirmed cases of COVID-19 worldwide exceeded 450 million,with more than 6 million deaths.[3]Since there is no specific therapeutic drug for the treatment of COVID-19,it is important to control the epidemic by actively promoting SARS-CoV-2 vaccination globally,reducing the risk of viral transmission and the incidence of severe COVID-19,thus improving prognoses.[4] | Junyan Jin Xiuwen Wang Raphael Carapito Christiane Moog Bin Su | 2022 | Infectious Diseases & Immunity2022，2，4： | 0 |
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