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| 1 | A clinical trial of CTLA-4 blockade with tremelimumab in patients with hepatocellular carcinoma and chronic hepatitis C显示文摘 | Bruno Sangro Carlos Gomez-Martin Manuel de la Mata Mercedes I?arrairaegui Elena Garralda Pilar Barrera Jose Ignacio Riezu-Boj Esther Larrea Carlos Alfaro Pablo Sarobe Juan José Lasarte Jose L. Pérez-Gracia Ignacio Melero Jesús Prieto | 2013 | Journal of Hepatology2013，，： | 6 |
| 2 | A half century (1961-2011) of applying microsurgery to experimental liver research显示文摘The development of microsurgery has been dependent on experimental animals. Microsurgery could be a very valuable technique to improve experimental models of liver diseases. Microdissection and microsutures are the two main microsurgical techniques that can be considered for classifying the experimental models developed for liver research in the rat. Partial portal vein ligation, extrahepatic cholestasis and hepatectomies are all models based on microdissection. On the other hand, in portacaval shunts, orthotopic liver transplantation and partial heterotopic liver transplantation, the microsuture techniques stand out. By reducing surgical complications, these microsurgical techniques allow for improving the resulting experimental models. If good experimental models for liver research are successfully developed, the results obtained from their study might be particularly useful in patients with liver disease. Therefore experimental liver microsurgery could be an invaluable way to translate laboratory data on liver research into new clinical diagnostic and therapeutic strategies. | Maria-Angeles Aller Natalia Arias Isabel Prieto Salvador Agudo Carlos Gilsanz Laureano Lorente Jorge-Luis Arias Jaime Arias | 2012 | World Journal of Hepatology2012，4，7： | 4 |
| 3 | Endoscopic and anesthetic feasibility of EUS and ERCP combined in a single session versus two different sessions显示文摘AIM:To discuss the feasibility of single session endoscopic ultrasonography(EUS) to discuss and endoscopic retrograde cholangiopancreatography(ERCP) execution.METHODS:Retrospective endoscopic and anesthetic outcome comparison of performing both EUS and ERCP in a single endoscopic session(Group Ⅰ) versus performing each procedure in two different sessions(Group Ⅱ) was made.The following variables were evaluated:epidemiological variables,American Society of Anesthesiologists Physical Status Classification(ASA) level,procedural time,propofol dose,anesthetic complications,endoscopic complications and diagnostic yield,and therapeutic procedures on both groups.T-student,ChiSquare and Fisher test were used for comparison.RESULTS:We included 39 patients in Group Ⅰ(mean age:69.85 ± 9.25;27 men) and 46 in Group Ⅱ(mean age:67.46 ± 12.57;25 men).Procedural time did not differ significantly between both groups(Group Ⅰvs Group Ⅱ:93 ± 32.78 vs 98.98 ± 38.17;P >0.05) but the dose of propofol differed(Group Ⅰ vs Group Ⅱ:322.28 ± 250.54 mg vs 516.96 ± 289.06 mg;P = 0.001).Three patients had normal findings on both explorations.Three anesthetic complications [O2 desaturation(2),broncoaspiration(1)] and 9 endoscopic complications [pancreatitis(6),bleeding(1),perforation(1),cholangitis(1)] occurred without significant differences between both groups(P > 0.05).We did not find any significant difference regarding age,sex,ASA scale level,diagnostic yield or therapeutic maneuvers between both groups.CONCLUSION:The performance of EUS and ERCP in a single session offers a similar diagnostic and therapeutic yield,does not entail a higher complication risk and requires a significantly smaller dose of propofol for sedation compared with performing each exploration in a different session. | Juan J Vila Marcos Kutz Silvia Goi Miriam Ostiz Edurne Amorena Carlos Prieto Cristina Rodriguez Ignacio Fernández-Urien Francisco J Jiménez | 2011 | World Journal of Gastrointestinal Endoscopy2011，3，3： | 3 |
| 4 | αKLOTHO and sTGFβR2 treatment counteract the osteoarthritic phenotype developed in a rat model显示文摘Dear Editor,Homeostasis and repair are critical biological processes that allow for tissue and organ preservation and function in multicellular organisms.Their regulation and extension vary drastically across the animal kingdom,and mammals show limited tissue-specific regenerative capacity that declines with age.During aging,articular cartilage is one of the tissues that undergo substantial changes in the matrix structure,molecular composition,metabolic activity,and mechanical properties(Loeser et al.2016). | Paloma Martinez-Redondo Isabel Guillen-Guillen Noah Davidsohn Chao Wang Javier Prieto Masakazu Kurita Fumiyuki Hatanaka Cuiqing Zhong Reyna Hernandez-Benitez Tomoaki Hishida Takashi Lezaki Akihisa Sakamoto Amy NNemeth Yuriko Hishida Concepcion Rodriguez Esteban Kensaku Shojima Ling Huang Maxim Shokhirev Estrella Nunez-Delicado Josep MCampistol Isabel Guillen-Vicente Elena Rodriguez-Inigo Juan Manuel Lopez-Alcorocho Marta Guillen-Vicente George Church Pradeep Reddy Pedro Guillen-Garcia Guang-Hui Liu Juan Carlos Izpisua Belmonte | 2020 | Protein & Cell2020，11，3： | 2 |
| 5 | Influence of temperature on protein hydrolysis in a cyclic batch enzyme membrane reactor显示文摘 | Carlos A Prieto Emilia M Guadix Antonio Guadix | 2008 | Biochemical Engineering Journal2008，42，： | 1 |
| 6 | Microbiological profiles, pH, and titratable acidity of Chorizo and Salchichon (Two Spanish dry fermented sausages ) manufactured with ostrich, deer, or pork meat 显示文摘 | Capita R Sandra L M Prieto M Carlos A C | 2006 | Journal of food protection2006，69，5： | 1 |
| 7 | Altas tasas de incidencia de enfermedad inflamatoria intestinal en Navarra. Resultados de un estudio prospectivo y poblacional显示文摘 | Antonio Arin Letamendia Fernando Borda Celaya M. Jesús Burusco Paternain Carlos Prieto Martínez Ana Martínez Echeverría Inmaculada Elizalde Apestegui Matilde Laiglesia Izquierdo Elena Macias Mendizábal Paolo Tamburri Moso Félix Sánchez Valverde | 2008 | Gastroenterologia y Hepatologia2008，，3： | 1 |
| 8 | A computer vision system for early detection of anthracnose in sugar mango(Mangifera indica)based on UV-A illumination显示文摘The present work describes the development of a computer vision system for the early detection of anthracnose in sugar mango based on Ultraviolet A illumination(UV-A).Anthracnose,a disease caused by the fungus Colletotrichum sp,is commonly found in the fruit of sugar mango(Mangifera indica).It manifests as surface defects including black spots and is responsible for reducing the quality of the fruit.Consequently,it decreases its commercial value.In more detail,this study poses a system that begins with image acquisition under white and ultraviolet illumination.Furthermore,it proposes to analyze the Red,Green and Blue color information(R,G,B)of the pixels under two types of illumination,using four different methods:RGB-threshold,RGB-Linear Discriminant Analysis(RGBLDA),UV-LDA,and UV-threshold.This analysis produces an early semantic segmentation of healthy and diseased areas of the mango image.The results showed that the combination of the linear discriminant analysis(LDA)and UV-A light(called UV-LDA method)in sugar mango images allows early detection of anthracnose.Particularly,this method achieves the identification of the disease one day earlier than by an expert with respect to the scale of anthracnose severity implemented in this work. | Leonardo Ramırez Alberto Carlos Eduardo Cabrera Ardila Flavio Augusto Prieto Ortiz | 2023 | Information Processing in Agriculture2023，10，2： | 1 |
| 9 | Optimal operation of a protein hydrolysis reactor with enzyme recycle 显示文摘 | Carlos A Prieto Emilia M | 2010 | Journal of Food Engineering2010，03，97： | 1 |
| 10 | A cyclic batch membrane reactor for the hydrolysis of whey protein 显示文摘 | Carlos A Prieto Antonio Guadix Pedro Gonza'lez-Tello | 2007 | Journal of Food Engineering2007，78，： | 1 |
| 11 | Aecurate pederian indtvor navigation by tightly coupling tixt-mounted IMU and RFID measurements显示文摘 | Antonio Ram6n Jim(mez Ruiz Fernamto Seco Granja Jo Carlos Prieto Honorato et a | 2012 | IEEE Transactions on lnstnHnentation anti Measurement2012，61，1： | 1 |
| 12 | A neural learning algorithm for blind separation of source based on geometric properties显示文摘 | Alberto prieto Carlos GPuntonet Beatriz Prieto | 1998 | Signal processing1998，64，3： | 1 |
| 13 | Improved procedures for estimating amplitudes andphases of harmonics with application to vibration analysis显示文摘 | Ignacio Santamaria Caballero Carlos J Pantaleon Prieto Jesus Ibanez Diaz | 1998 | IEEE Transactions on Instrumentation and Measurement1998，47，1： | 1 |
| 14 | Laparoscopic extended cardiomyotomy in children: an effective procedure for the treatment of esophageal achalasia显示文摘 | Ana Cristina Aoun Tannuri Uenis Tannuri Manoel Carlos Prieto Velhote Rodrigo Luiz Pinto Rom?o | 2010 | Journal of Pediatric Surgery2010，，7： | 1 |
| 15 | Nanobiotechnological approsch to engineered biomaterial design: the example of elastin- like polymers 显示文摘 | Rodriguez- Cabello J Carlos Prieto S | 2006 | Nanomedicine2006，14，3： | 1 |
| 16 | Temporal localization of porcine reproductive and respiratory syndrome virus in reproductive tissues of experimentally infected boars 显示文摘 | Cinta Prieto Carlos Garcl'a Isabel Simarro | 2003 | Theriogenology2003，60，： | 1 |
| 17 | Farmacocinetica de cefquinome en terneros por aplicacion intra- muscular显示文摘 | Carlos A Errecalde MV Esp Cs Clin Guillermo F Prieto | 2002 | Rev Col Cienc Pec2002，15，3： | 1 |
| 18 | Accurate Pedestrian Indoor Navigation by Tightly Coupling Foot-Mounted IMU and RFID Measurements显示文摘 | Antonio Ram6n Jim6nez Ruiz Fernando Seco Granja Jos: Carlos Prieto Honorato | 2012 | IEEE Transactions on Instrumentation and Measurement2012，61，1： | 1 |
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