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9篇 您的检索式：作者名="Carol Ward"

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		题名	作者	年代	出处	被引量
	1	Predictive markers of endocrine response in breast cancer显示文摘Ongoing clinical and research efforts seek to optimise the use of endocrine therapy in the treatment of breast cancer. Accurate biomarkers are needed that predict response for individual patients. The presence of the estrogen receptor(ER) as the direct(for tamoxifen and fulvestrant) or indirect(for aromatase inhibitors) target molecule for endocrine therapy remains the foremost biomarker and determinant of response. However, ER expression only poorly predicts outcome and further indicators of response or resistance are required. The development and application of molecular signature assays such as Oncotype Dx, Prosigna, Mammaprint and Endopredict have provided valuable information on prognosis and these are being used to support clinical decision making on whether endocrine therapy alone alongside surgery is sufficient for ER-positive early stage breast cancers or whether combination of endocrine with chemotherapy are also warranted. Ki67, the proliferation marker, has been widely used in the neo-adjuvant(pre-operative) setting to help predict response and long term outcome. Gene expression studies within the same setting have allowed monitoring of changes of potential predictive markers. These have identified frequent changes in estrogenregulated and proliferation genes. Specific molecules such as mutant ER may also prove helpful biomarkers in predicting outcome and monitoring response to treatment.	Duniya Mosly Arran Turnbull Andrew Sims Carol Ward Simon Langdon	2018	World Journal of Experimental Medicine2018，8，1：	2
	2	Diagnosis and Management of Childhood Obstructive Sleep Apnea Syndrome显示文摘	Carole L. Marcus Lee J. Brooks Sally Davidson Ward Kari A. Draper David Gozal Ann C. Halbower Jacqueline Jones Christopher Lehmann Michael S. Schechter Stephen Sheldon Richard N. Shiffman Karen Spruyt	2012	PEDIATRICS2012，，3：	1
	3	Human Evolution and the Development of Spondylolysis显示文摘	Carol V. Ward Bruce Latimer	2005	Spine2005，，16：	1
	4	10 Bold Steps to Prevent Burnout in General Internal Medicine显示文摘	Mark Linzer Rachel Levine David Meltzer Sara Poplau Carole Warde Colin P. West	2014	Journal of General Internal Medicine2014，，1：	1
	5	Childhood and adolescent cancer statistics, 2014显示文摘	Elizabeth Ward Carol DeSantis Anthony Robbins Betsy Kohler Ahmedin Jemal	2014	CA A Cancer Journal for Clinicians2014，，2：	1
	6	A systematic review and meta-analysis of KRAS status as the determinant of response to anti-EGFR antibodies and the impact of partner chemotherapy in metastatic colorectal cancer显示文摘	Barbara-Ann Adelstein Timothy A. Dobbins Carole A. Harris Ian C. Marschner Robyn L. Ward	2011	European Journal of Cancer2011，，9：	1
	7	Avoiding an incision through the anterior previa at cesarean delivery显示文摘	Carol R Ward	2003	Obstetrics & Gynecology2003，，3：	1
	8	rhIGF-1 administration reduces insulin requirements,decreases growth hormone secretion,and improves the lipid profile in adults with IDDM显示文摘	CAROLL P V UMPLEBY M WARD G S	1997	Diabetes1997，46，：	1
	9	A programmable micropropagation apparatus using cycled liquid medium显示文摘	Ward Simonton Carol Robacker Scott Krueger	1991	Plant Cell, Tissue and Organ Culture1991，，2：	1

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