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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Insulin resistance impairs sustained response rate to peginterferon plus ribavirin in chronic hepatitis C patients显示文摘 | Manuel Romero-Gómez Maria Del Mar Viloria Raúl J. Andrade Javier Salmerón Moisés Diago Conrado M. Fernández-Rodríguez Raquel Corpas Marina Cruz Lourdes Grande Luis Vázquez Paloma Mu?oz-de-Rueda Pilar López-Serrano Ana Gila María L. Gutiérrez Celia Pérez A | 2005 | Gastroenterology2005，，3： | 2 |
| 3 | Radiation therapy fol- lowing surgery or localized breast cancer:outcome predic- tion by classical prognostic factors and approximated ge- netic subtypes显示文摘 | Pacelli R Conson M Celia L | 2013 | J Radiat Res2013，54，2： | 1 |
| 4 | A general mass-conservative numerical solution for the unsaturated flow equation显示文摘 | Celia M A Bouloutas E T Zarba R L | 1990 | Water Resour Res1990，26，： | 1 |
| 5 | A general mass-conservative numerical solution for the unsaturated flow equation显示文摘 | Celia M A Bouloutas E T Zarba R L | 1990 | Water Resource1990，，26： | 1 |
| 6 | Prediction of relative permeabilities for unconsolidated soil using pore - scale network models显示文摘 | Rajarama H Ferrand L A Celia M A | 1997 | Water Resources Research1997，33，： | 1 |
| 7 | Diversity, Endemism and Conservation of Ferns(Polypodiales) in the Mexican Mountain Component显示文摘We analyzed the distributional patterns of95 selected species of leptosporangiate ferns inhabiting the Mexican Mountain Component, using grid-cells of one geographical degree as unit areas,applying endemism indices and richness and beta diversity analyses.Distributional data were obtained from several herbaria and specialized literature.Five grid-cells appear to be important for fern species richness, as they contain 35 to 49 species.These gridcells are located in the Sierra Madre Oriental(SMO),Trans-Mexican Volcanic Belt(TMVB) and the Sierra Madre del Sur(SMS).Mean richness by latitudinal belts of one degree showed that the belts with highest values are related to the TMVB and SMS.A total of 13grid-cells were recognized as important from theperspective of endemism; most of them are located also in the SMO, TMVB and SMS.The richest gridcells coincided with one of the main centres of endemism for ferns obtained in this study, located in the convergence of the southern part of the SMO, the eastern portion of the TMVB and the northern part of the SMS, reflecting the high humidity existing on the mountain slopes facing the Gulf of Mexico.Some important grid-cells recognized from richness and endemism analyses coincide with Mexican Natural Protected Areas.The beta diversity analysis showed a low degree of similarity among grid-cells, implying a high species replacement, as the result of environmental heterogeneity occurring in the Mexican mountain systems.On the other hand, the spatial analysis suggested a pattern of phytogeographical regionalization comprising twomain areas: the Mexican Transition Zone and the Mexican Central Plateau.Ferns play an important role in the Mexican biodiversity and contributing to the beta diversity of Mexico. | SANGINéS-FRANCO Celia LUNA-VEGA Isolda CONTRERAS-MEDINA Raúl ESPINOSA David TEJERO-DíEZ José Daniel RIVAS Gerardo | 2015 | Journal of Mountain Science2015，12，4： | 1 |
| 8 | Validation of FACT/GOG-AD subscale for ovarian cancer-related abdominal discomfort: a Gynecologic Oncology Group study 显示文摘 | Wenzel L Huang HQ Celia D | 2008 | GynecolOncol2008，110，1： | 1 |
| 9 | Effect of DOPO units and of polydimethylsiloxane segments on the properties of epoxy resins显示文摘 | Corneliu Hamciuc Diana Serbezeanu Ionela-Daniela Carja Tachita Vlad-Bubulac Valentina-Elena Musteata Vicente Forrat Pérez Celia Guillem López Angel M. López Buendia | 2013 | Journal of Materials Science2013，，24： | 1 |
| 10 | Orthogonal collocation and alternating-direction procedures for unsaturated flow problems显示文摘 | Celia M A Ahuja L R Pinder G F | 1987 | Advances in Water Resources1987，10，4： | 1 |
| 11 | A general mass-conservative numerical solution for the unsaturated flow equation显示文摘 | Celia M A Bouloutas E T Zarba R L | 1990 | Water Resource Reseacher1990，26，7： | 1 |
| 12 | Successful imple- mentation of evidence-based nursing practice : the indis- pensable role of staff development 显示文摘 | Wittmann-Price R Celia L Dunn R | 2013 | J Nurses Prof Dev2013，29，4： | 1 |
| 13 | Chlorpromazine Interactions to Sera Albumins: A Study by the Quenching of Fluorescence 显示文摘 | Dilson S Celia M C Sonia R W L | 2004 | Speetrochim Aeta Part A2004，60，5： | 1 |
| 14 | Nano aptasensor for protective antigen toxin of anthrax显示文摘 | Celia L N Sanchez P Zhong W | 2010 | Anal Ctlem2010，82，5： | 1 |
| 15 | Fractionated stereot- actic radiation therapy for orbital optic nerve sheath menin-gioma-a single institution experience and a short review of the literature 显示文摘 | Pacelli R Celia L Consort M et ol | 2011 | J Radiat Res2011，52，1： | 1 |
| 16 | A general mass-con- servative numerical solution for the unsaturated flow equation 显示文摘 | Celia M A Bouloutas E T Zarba R L | 1990 | Water Resources Research1990，26，7： | 1 |
| 17 | Radiation therapy in primary orbital lymphoma: A single institution retrospective analysis 显示文摘 | De Cicco L Celia L Liuzzi R | 2009 | Radiat Oncol2009，，4： | 1 |
| 18 | Sequential and opposing alterations of 5-HT1A receptor function during withdrawal from chronic morphine显示文摘 | Pierre-Eric L Amynah AP Celia G | 2011 | Eur Neuropsychopharmacol2011，21，11： | 1 |
| 19 | Heat-shock proteins expression in fish central nervous system and its possible relation with water acidosis resistance显示文摘 | MART(I)N Monserrat CELIA Herna'ndez GUILLERMO Bodega l | 1998 | Neuroscience Research1998，31，： | 1 |
| 20 | A general mass-conservative numerical solution for the unsaturated flow equation 显示文摘 | Celia M A Bouloutas E T Zarba R L | 1990 | Water Resources Research1990，26，7： | 1 |
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