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| 1 | Patterns of regional recurrence after curative D2 resection for stage III (N3) gastric cancer: Implications for postoperative radiotherapy显示文摘 | Jee Suk Chang Joon Seok Lim Sung Hoon Noh Woo Jin Hyung Ji Yeong An Yong Chan Lee Sun Young Rha Chang Geol Lee Woong Sub Koom | 2012 | Radiotherapy and Oncology2012，，3： | 4 |
| 2 | Intervertebral disc development and disease-related genetic polymorphisms显示文摘The intervertebral disc(IVD)comprises a gelatinous inner core(nucleus pulposus;NP)and concentric rings(annulus fibrosus;AF).The NP,an important structure for shock absorption in the vertebrate spinal motion segment,can be traced back to the notochord in ontogenetic lineage.In vertebrates,the notochord undergoes mucinoid changes,and had been considered vestigial until recently.However,observed correlations between IVD degeneration and back pain in humans have renewed interest in the IVD in biomedical fields.Beyond its mechanical contribution to development,the notochord is also an essential signaling center,which coordinates formation of the neural tube and somites.The pertinent signaling molecules,particularly TGF-b and bone morphogenetic proteins(BMPs),continue to play roles in the adult tissues and have been utilized for tissue regeneration.Genetic factors are major determinants of who will develop IVD degeneration and related back pain,and seem to correlate better with disc degeneration and back pain than do external forces on the spine.In summary,the spinal column is a landmark development in evolution.Genes directing the development of the IVD may also contribute to its maintenance,degeneration,and regeneration.Likewise,structural genes as well as genes responsible for maintenance of the structure are related to IVD degeneration.Finally,genes responsible for inflammation may play a dual role in exacerbating degeneration or facilitating repair responses depending on the context. | Jason W.Ashley Motomi Enomoto-Iwamoto Lachlan J.Smith Robert L.Mauck Danny Chan Joseph Lee Martin F.Heyworth Howard An Yejia Zhang | 2016 | Genes & Diseases2016，3，3： | 3 |
| 3 | Over-expression of nm23-H1 in HeLa cells provides cells with higher resistance to oxidative stress possibly due to raising intracellular p53 and GPX显示文摘瞄准:决定反肿瘤因素 nm23 是否与反氧化是相关的。方法:全身的人的 nm23-H1 被克隆进哺乳动物表示的向量并且短暂地介绍了房间进 HeLa。结果:反应的氧种类(ROS ) 显著地低级的 A 在细胞被检测过去表示的 nm23-H1。3-(4,5-Dimethylthiazol-2-yl )-2,5-diphenyltetrazolium 溴化物和尝试平底锅蓝色试金发现有一个 nm23-H1-expressing 原生质标志的房间 transfected 有更高的生存能力和更强壮的抵抗到氧化应力。Immunoprecipitation 测试表明内长的 nm23-H1 与 p53 形成了蛋白质建筑群。而且, p53 的细胞内部的层次和 p53-regulatedgene GPX1 显然在表示 nm23-H1 上在房间被增加。下面在在表示 nm23-H1 上的房间的 p53 的规定导致了更高细胞的 ROS 水平和更低的房间生存能力。结论:调查结果建议 nm23-H1 可以对氧化应力充当一个细胞的保护者,可能触发 p53 相关的抗氧化的小径。 | Run AN Yong-lie CHU Chan TIAN Xiao-xia DAI Jing-hong CHEN Qi SHI Jun HAN Xiao-ping DONG | 2008 | Acta Pharmacologica Sinica2008，29，12： | 2 |
| 4 | Genome-Wide Identification and Validation of a Novel Methylation Biomarker, SDC2 , for Blood-Based Detection of Colorectal Cancer显示文摘 | TaeJeong Oh Nayoung Kim Youngho Moon Myung Soon Kim Benjamin D. Hoehn Chan Hee Park Tae Soo Kim Nam Kyu Kim Hyun Cheol Chung Sungwhan An | 2013 | The Journal of Molecular Diagnostics2013，，4： | 2 |
| 5 | Dimension and frequency of bar formation in a braided river显示文摘This paper presents flume and field observations of a bank-confined braided river.Morphological features,including plan form configuration,channel width,and main channel migration,were examined by a series of experiments.Repeated measurements of channel morphology,provided a basis to estimate the relationship between noncumulative frequency of bars and bar area.Additional results from the Dajia River,located in Central Western Taiwan,were presented to provide a reference data set for comparing the laboratory and field data.The results indicate that the relationship between bar length and width can be predicted by a simple best-fit power function relating to self-similarity characteristics.The Hurst index by Walsh and Hicks(2002) provides acceptable predictions of the bar length and width observed in the experiments and confirmed by the field investigations.Eexperimental and field results both show that large river width yields a uniform distribution of bar areas with the similar discharge,leading to a large value of exponent(ft) in the model.The river width is confirmed to be a critical parameter in the main channel shift.A small increase in channel width likely increased rapidly the shift cycle. | Hsuan-pei AN Su-chin CHEN Hsun-chuan CHAN Yi HSU | 2013 | International Journal of Sediment Research2013，28，3： | 2 |
| 6 | Discovering rules for water demand prediction:an enhanced rough _ set approach显示文摘 | Shan N Chan C | 1996 | Engineering applications in artificial intelligence1996，9，6： | 1 |
| 7 | Discovering rules for water demand prediction: An enhanced rough-set approach显示文摘 | An A Shan N Chan C | 1996 | Engineering Application and Artificial Intelligence1996，9，6： | 1 |
| 8 | Discovering rules for water demana'prediction: An enhanced rough-set approach显示文摘 | An A Shall N Chan C | 1996 | Engineering Application and Artificial Intelligence1996，9，6： | 1 |
| 9 | The role of eiprofloxacin in prolongin polyethylene biliary stent patencv: a muhieenter, double-blinded eftectiveness study 显示文摘 | Chan G Barkun J Barkun AN | 2005 | J Gastrointest Sur2005，9，4： | 1 |
| 10 | First analysis of 10 - year trends in national factor concentrates usage in haemophilia: data from CHARMS, the Canadian Hemophilia Assessment and Resource Management System显示文摘 | Traore AN Chan AK Webert KE | 2014 | Haemophilia2014，20，4： | 1 |
| 11 | Defining the target volume for post-operative radiotherapy after D2 dissection in gastric cancer by CT-based vessel-guided delineation<!-- CT-based vessel-guided target volume delineation -->显示文摘 | Hong In Yoon Jee Suk Chang Joon Seok Lim Sung Hoon Noh Woo Jin Hyung Ji Yeong An Yong Chan Lee Sun Young Rha Kyung Hwan Kim Woong Sub Koom | 2013 | Radiotherapy and Oncology2013，，： | 1 |
| 12 | Discovering rules for water demand prediction: An enhanced rough-set approach显示文摘 | AN A Shan N Chan C | 1996 | Engineering Application and Artificial Intelligence1996，9，6： | 1 |
| 13 | Discovering rules for water demand prediction:An enhanced rough-set approach显示文摘 | An A Shan N Chan C | 1996 | Engineering Applications in Artificial Intelligence1996，9，6： | 1 |
| 14 | Control of calcium hexaluminate grain morphology in in-situ toughened ceramic composites 显示文摘 | An L Chan H M Soni K K | 1996 | Journal of Materials Science1996，31，12： | 1 |
| 15 | Cure monitoring of smart composites using fiber Bragg grating based显示文摘 | CHAN P Y Ong L S | 2000 | Sensors aand Actuators2000，79，： | 1 |
| 16 | Digital PCR analysis of maternal plasma for noninvasive detection of sickle cell anemia 显示文摘 | Barrett AN McDonnell TC Chan KC | 2012 | Clin Chem2012，58，6： | 1 |
| 17 | Mesenehymal stem cells induce dermal fibroblast responses to injury 显示文摘 | Smith AN Willis E Chan VT | 2010 | Experimental Cell Research2010，316，1： | 1 |
| 18 | Transeriptome -wide characterization of miRNA- directed and non - miRNA - directed endonncleolytic cleavage using degradome analysis under low ambient temperature in Phalaenopsis aphrodite subsp, formosana显示文摘 | An F M Chan M T | 2012 | Plant & Cell Physiol- ogy2012，53，10： | 1 |
| 19 | Photochemical repair of Achilles tendon rupture in a rat model显示文摘 | Chan BP Amann C Yaroslavsky AN | 2005 | J Surg Res2005，124，2： | 1 |
| 20 | Systematic nodal dis- section in the intrathoracic staging of patients of patients with non-small cell lung cancer显示文摘 | Graham AN Chan KJ Pastorino U | 1999 | J Thorac Cardiovasc Surg1999，117，2： | 1 |
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