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| 1 | Upconversion nano-photosensitizer targeting into mitochondria for cancer apoptosis induction and cyt c fluorescence monitoring显示文摘反应的氧种类(mitoROS ) 玩的 mitochondrial 的混乱在癌症房间 apoptosis 的一个主要角色。这里,我们设计了 core/shell-structured 有由 photosensitizer (PS ) 涂的核心合并了的做 lanthanide 的 upconversion nanoparticle (UCNP ) 的指向线粒体的基于 upconversion 的使 nano 具有感光性(TPP-UC (PS )) 稠密的硅石壳。有外部在红外线附近的激光(NIR ) 的后面的照耀,在引起为激活的基于 upconversion 的光力学的治疗(UC 太平洋夏季时间) 胀大的严肃的 mitochondrial 矩阵的线粒体的 TPP-UC (PS ) ,和细胞色素 c (cyt c ) 的动员响应增加的 mitoROS 被放大。明确地,这包含 heme cyt c 能被改变 TPP-UC (PS ) s upconversion 光信号(UCL ) 监视,它可以便于在里面为 apoptosis 研究的 cyt c 的 situ 察觉。作为概念的一个证明,我们的设计 TPP-UC (PS ) 可以为在 NIR 刺激下面控制癌症房间 apoptosis 并且为用动态 UCL 学习 apoptosis 提供重要机会,它被本地 cyt c 影响。 | Yanyan Liu Jiawen Zhang Changjing Zuo Zhen Zhang Dalong Ni Chen Zhang Jing Wang Hui Zhang Zhenwei Yao Wenbo Bu | 2016 | Nano Research2016，9，11： | 8 |
| 2 | Nonlinear Maps Preserving the Jordan Triple *-Product on Factor von Neumann Algebras显示文摘Let A and B be two factor von Neumann algebras. For A, B ∈ A, define by [A, B]_*= AB-BA~*the skew Lie product of A and B. In this article, it is proved that a bijective map Φ : A → B satisfies Φ([[A, B]_*, C]_*) = [[Φ(A), Φ(B)]_*, Φ(C)]_*for all A, B, C ∈ A if and only if Φ is a linear *-isomorphism, or a conjugate linear *-isomorphism, or the negative of a linear *-isomorphism, or the negative of a conjugate linear *-isomorphism. | Changjing LI Quanyuan CHEN Ting WANG | 2018 | Chinese Annals of Mathematics,Series B2018，39，4： | 5 |
| 3 | Efficient production of chemicals from microorganism by metabolic engineering and synthetic biology显示文摘The use of traditional chemical catalysis to produce chemicals has a series of drawbacks,such as high dependence on fossil resources,high energy consumption,and environmental pollution.With the development of synthetic biology and metabolic engineering,the use of renewable biomass raw materials for chemicals synthesis by constructing efficient microbial cell factories is a green way to replace traditional chemical catalysis and traditional microbial fermentation.This review mainly summarizes several types of bulk chemicals and high value-added chemicals using metabolic engineering and synthetic biology strategies to achieve efficient microbial production.In addition,this review also summarizes several strategies for effectively regulating microbial cell metabolism.These strategies can achieve the coupling balance of material and energy by regulating intracellular material metabolism or energy metabolism,and promote the efficient production of target chemicals by microorganisms. | Yang Zhang Jing Yu Yilu Wu Mingda Li Yuxuan Zhao Haowen Zhu Changjing Chen Meng Wang Biqiang Chen Tianwei Tan | 2021 | Chinese Journal of Chemical Engineering2021，34，2： | 2 |
| 4 | STEADY-STATE RESPONSE OF A TIMOSHENKO BEAM ON AN ELASTIC HALF-SPACE UNDER A MOVING LOAD显示文摘由介绍与一根 Timoshenko 横梁交往的有弹性的一半空间的相等的僵硬,在有弹性的 half-spacesubjected 上休息到动人的负担的横梁的排水量答案被介绍。基于thehalf空间和横梁的波浪速度的相对关系,有 half-spaceand 的不同参数的联合的四格横梁,软横梁的系统和难一半空间, 亚soft 横梁和hardhalf空间的系统, 亚hard 横梁的系统和软一半空间,并且难横梁和softhalf空间的系统被考虑。动人的负担的批评速度用分散曲线被学习。Timoshenko 横梁上的动人的负担的批评速度取决于一半空间和横梁的波浪速度的相对关系,这被发现。在一半空间的瑞利波浪速度总是是批评速度,当负担速度到达它时,系统的反应将是无限的。为软横梁和难一半空间的系统,横梁的波浪速度也是批评速度。除横梁的 shear 波浪速度以外,为亚 soft 横梁和难一半空间的系统有另外的最小的批评速度。当时为系统(潜水艇 --) 难横梁和软一半空间,横梁的波浪速度不再是批评的。有 Euler-Bernoulli 横梁的比较证明横梁的二种类型的批评速度和回答为系统是不同的(潜水艇 --) 软横梁和难一半空间但是类似于为系统的对方(潜水艇 --) 难横梁和软一半空格。横梁的最大的排水量几乎在负担的地点,如果负担速度比最小的批评速度(为软横梁和难一半空间的系统的横梁的 shear 波浪速度) 小,沿着横梁的排水量是几乎对称的。在负担和沿着横梁的排水量的不对称现象后面的横梁移动的最大的排水量由于抑制和波浪放射随负担速度的增加增加。如果负担速度比横梁和一半的最大的波浪速度大,在负担的前面的横梁的排水量是很小的空间。现在的学习的结果为 high-speedtrain 导致的地面颤动的分析提供吸引人的理论、实际的参考书。 | Chen Vunmin Wang Changjing | 2006 | Acta Mechanica Solida Sinica2006，19，1： | 2 |
| 5 | Efficacy and Safety of Cinitapride in the Treatment of Mild to Moderate Postprandial Distress Syndrome–predominant Functional Dyspepsia显示文摘 | Yiqi Du Tun Su Xinmiao Song Jun Gao Duowu Zou Changjing Zuo Weifen Xie Bangmao Wang Zhiguang Zhang Jianming Xu Dean Tian Hesheng Luo Zhenyu Zhang Shaofeng Wang Jianping Chen Jizhong Guo Lei Gong Yanbing Ding Zhaoshen Li | 2014 | Journal of Clinical Gastroenterology2014，，4： | 1 |
| 6 | Atrial size reduction as a predictor of the success of radiofrequency maze procedure for chronic atrial fibrillation in patients undergoing concomitant valvular surgery 显示文摘 | CHEN M C CHANGJ P GUO G B | 2001 | J Cardiovasc Eleetr-ophysiol2001，12，8： | 1 |
| 7 | Microstructure and electrochemical characteristics of aluminum anodized film formed in ammonium adipate solution 显示文摘 | ChangJ K Liao C M Chen C H | 2003 | Journal of the Electrochemical Society2003，，6： | 1 |
| 8 | Synthesis,separation,and theoretical studies of chiral biphenyl ligands (α-and β-DDB)显示文摘 | CHANGJ B CHEN R F GUO R Y | 2003 | Helv Chim Acta2003，86，： | 1 |
| 9 | Atrial size reduction as a predictor of the success of radiofrequency maze procedure for chronic atrial fibrillation in patients undergoing concomitant valvular surgery显示文摘 | CHEN MC CHANGJ P GUO G B et at | 2001 | J Cardiovasc Electrophysiol2001，12，： | 1 |
| 10 | Synthesis of β-cyclodextrin modified chitosan–poly(acrylic acid) nanoparticles and use as drug carriers显示文摘 | Xue Wang Changjing Chen Da Huo Hanqing Qian Yin Ding Yong Hu Xiqun Jiang | 2012 | Carbohydrate Polymers2012，，1： | 1 |
| 11 | *-Lie Derivable Mappings on Von Neumann Algebras显示文摘In this paper,we prove that every*-Lie derivable mapping on a von Neu-mann algebra with no central abelian projections can be expressed as the sum of anadditive*-derivation and a mapping with image in the center vanishing at commuta-tors. | Changjing Li Quanyuan Chen Ting Wang | 2016 | Communications in Mathematics and Statistics2016，4，1： | 1 |
| 12 | Surgical treatment of oral verrucous carcinoma显示文摘 | Kang C J ChangJ T Chen T M | 2003 | Chang Gung Med J2003，26，11： | 1 |
| 13 | Competitive biosorption of azo dyes from aqueous solution on the templated crosslinked-chitosan nanoparticles显示文摘 | Chen C Y ChangJ C Chen A H | 2011 | Journal of Hazard?ous Materials2011，185，1： | 1 |
| 14 | Preparation of porous chitosan-poly(acrylic acid)-calcium phosphate hybrid nanoparticles via mineralization显示文摘In this work, the preparation of chitosan-poly(acrylic acid)-calcium phosphate hybrid nanoparticles (CS-PAA-CaP NP) based on the mineralization of calcium phosphate (CaP) on the surface of chito-san-poly (acrylic acid) nanoparticles (CS-PAA NPs) was reported. CS-PAA-CaP NPs were achieved by directly adding ammonia to the aqueous solution of CS-PAA nanoparticles or by thermal decomposi-tion of urea in the aqueous solution of CS-PAA nanoparticles, resulting in the mineralization of CaP on the surface of CS-PAA NPs. Through these two routes, especially using urea as a pH-regulator, the precipitation of CS-PAA NPs, a common occurrence in basic environment, was avoided. The size, morphology and ingredient of CS-PAA-CaP hybrid nanoparticles were characterized by dynamic light scattering (DLS), transmission electron microscope (TEM), scanning electron microscope (SEM), thermogravimetry analysis (TGA) and X-ray diffractometer (XRD). When urea was used as the pH regulator to facilitate the mineralization during the thermal urea decomposition procedure, regular CS-PAA-CaP hybrid nanoparticles with a porosity-structural CaP shells and 400―600 nm size were obtained. TGA result revealed that the hybrid NPs contained approximately 23% inorganic component, which was consistent with the ratio of starting materials. The XRD spectra of hybrid nanoparticles in-dicated that dicalcium phosphate (DCP: CaHPO4) crystal was a dominant component of mineralization. The porous structure of the CS-PAA-CaP hybrid NPs might be greatly useful in pharmaceutical and other medical applications. | CHEN ChangJing DENG Yu YAN ErYun HU Yong JIANG XiQun | 2009 | Chinese Science Bulletin2009，54，18： | 0 |
| 15 | A Method to Deduce and Synthesize the Dafny Programs显示文摘We propose a systematic method to deduce and synthesize the Dafny programs.First,the specification of problem is described in strict mathematical language.Then,the derivation process uses program specification transformation technology to perform equivalent transformation.Furthermore,Dafny program is synthesized through the obtained recursive relationship and loop invariants.Finally,the functional correctness of Dafny program is automatically verified by Dafny verifier or online tool.Through this method,we deduce and synthesize Dafny programs for many typical problems such as the cube sum problem,the minimum(or maximum)contiguous subarray problems,several searching problems,several sorting problems,and so on.Due to space limitation,we only illustrate the development process of Dafny programs for two typical problems:the minimum contiguous subarray problem and the new local bubble sorting problem.It proves that our method can effectively improve the correctness and reliability of Dafny program developed.What’s more,we demonstrate the potential of the deductive synthesis method by developing a new local bubble Sorting program. | WANG Changjing DING Xilong HE Jiangfei CHEN Xi HUANG Qing LUO Haimei ZUO Zhengkang | 2021 | Wuhan University Journal of Natural Sciences2021，26，6： | 0 |
| 16 | Effect of Grain Size on Phase Transformation and Photoluminescence Property of the Nanocrystalline ZrO_2 Powders Prepared by Sol-Gel Method显示文摘Nanocrystalline zirconia(Zr O2) powders were prepared by a sol e gel process followed by annealing treatments from 500 to 1200 C. Phase transformation, microstructural features and photoluminescence properties were characterized by X-ray diffraction, transmission election microscopy and photoluminescence spectra,respectively. The results show that both monoclinic phase and tetragonal phase exist in the nanocrystalline Zr O2 powders at annealing temperature in the range of 500e900 C, and the concentration of monoclinic phase increases with increasing the annealing temperature. Tetragonal phase is totally transformed to monoclinic phase when annealing temperature is up to 900 C. The average grain size of the powders also increases when annealing temperature increases. Two emission peaks centered at 390 nm(named as I390)and 470 nm(named as I470) exist in the photoluminescence spectra, and the intensity ratio of I390 to I470decreases with increasing annealing temperature. The grain size is proposed to be responsible for the phase transformation in the nanocrystalline Zr O2 powders. | Qiong Chen Yongqin Chang Changjing Shao Jing Zhang Jun Chen Mingwen Wang Yi Long | 2014 | Journal of Materials Science & Technology2014，30，11： | 0 |
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