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| 1 | Microencapsulation of nutmeg essential oil by spray-drying with different wall materials显示文摘Nutmeg essential oil with volatile components is sensitive to oxygen, light, water and high temperature. Spray-drying is widely used as an encapsulation technique for improving compound stability during processing and storage. In this study, influence of encapsulated matrix on spray-dried nutmeg essential oil microcapsule was investigated using blends of maltodextrin and either gum Arabic(GA-MD), or octenyl succinic acid modified starch(OSA-MD) as wall materials. Characteristics of spray-dried powders from these 2 wall materials were evaluated and compared. Powder property analysis indicated that GA-MD microcapsules presented larger size, higher moisture and poorer flowability compared with OSA-MD microcapsules. Fourier transforms infrared spectroscopy and thermogravimetric analysis showed that both GA-MD and OSA-MD microcapsules improved the stability of nutmeg essential oil. However, GA-MD microcapsules exhibited higher storage stability than OSA-MD microcapsules. This research provided theoretical foundation for wall material choice of microcapsule and nutmeg essential oil utilization in food industry. | Xuyan Dong Bangfu Wu Qianchun Deng Fang Wei Hong Chen Chen Yang Renhuai Cong Chayan Wan Xin Lv Fenghong Huang | 2018 | Oil Crop Science2018，3，4： | 2 |
| 2 | Administration-time-dependenteffects of olmesartan on the ambulatory blood pressure of essentialhypertensionpatients显示文摘 | Hermida RC Ayala DE Chayan L | 2009 | ChronobiolInt2009，26，1： | 1 |
| 3 | Administrationtime-dependent effects of olmesartan on the ambulstory blood pressure of essential hypertension patients显示文摘 | Hermida Rc Ayala DE Chayan L | 2009 | Chronobiol Int2009，26，： | 1 |
| 4 | Gender differences in the administration time dependent efficacy of telmisartan on ambula- tory blood pressure in essential hypertension显示文摘 | Ayala DE Hermida RC Chayan L | 2009 | J Clin Hyper- tens2009，11，4： | 1 |
| 5 | Sulfur-containing glucosides from Clinacanthus nutans显示文摘 | Ko-Ichiro Teshima Tetsuo Kaneko Kazuhiro Ohtani Ryoji Kasai Sorasak Lhieochaiphant Chayan Picheansoonthon Kazuo Yamasaki | 1998 | Phytochemistry1998，，： | 1 |
| 6 | Gender differences in the administration time dependent efficacy of telmisartan on ambulatory blood pressure in essential hypertension显示文摘 | Ayala DE Hermida RC Chayan L | 2009 | J Clin Hypertens2009，11，41： | 1 |
| 7 | Administration-time: dependent effects of nifedipine gits on morning blood pressure surge in essential hypertension显示文摘 | Hermida RC Ayala DE Chayan L | 2009 | J Clin Hypertens2009，11，41： | 1 |
| 8 | Comparison of the effects on ambulatory blood pressure of awakening versus bedtime administration of torasemide in essential hypertension 显示文摘 | Hermida RC Ayala DE Chayan L | 2009 | J Clin Hypertens2009，11，41： | 1 |
| 9 | Value of neutrophil-lymphocyte ratio in evaluating response to percutaneous catheter drainage in patients with acute pancreatitis显示文摘BACKGROUND Early prediction of response to percutaneous catheter drainage(PCD)of necrotic collections in acute pancreatitis(AP)using simple and objective tests is critical as it may determine patient prognosis.The role of white blood cell(WBC)count and neutrophil-lymphocyte ratio(NLR)has not been assessed as a tool of early prediction of PCD success and is the focus of this study.AIM To assess the value of WBC and NLR in predicting response to PCD in AP.METHODS This retrospective study comprised consecutive patients with AP who underwent PCD between June 2018 and December 2019.Severity and fluid collections were classified according to the revised Atlanta classification and organ failure was defined according to the modified Marshall Score.WBC and NLR were monitored 24 h prior PCD(WBC-0/NLR-0)and 24 h(WBC-1/NLR-1),48 h(WBC-2/NLR-2)and 72 h(WBC-3/NLR-3)after PCD.NLR was calculated by dividing the number of neutrophils by the number of lymphocytes.The association of success of PCD(defined as survival without the need for surgery)with WBC and NLR was assessed.The trend of WBC and NLR was also assessed post PCD.RESULTS One hundred fifty-five patients[median age 40±13.6(SD),64.5%males,53.5%severe AP]were included in the final analysis.PCD was done for acute necrotic collection in 99(63.8%)patients and walled-off necrosis in 56(36.1%)patients.Median pain to PCD interval was 24±69.89 d.PCD was successful in 109 patients(group 1)and 46 patients(group 2)who failed to respond.There was no significant difference in the baseline characteristics between the two groups except the severity of AP and frequency of organ failure.Both WBC and NLR showed an overall decreasing trend.There was a significant difference between WBC-0 and WBC-1(P=0.0001).WBC-1 and NLR-1 were significantly different between the two groups(P=0.048 and 0.003,respectively).The area under the curve of WBC-1 and NLR-1 for predicting the success of PCD was 0.602 and 0.682,respectively.At a cut-off value of 9.87 for NLR-1,the sensitivity and specificity for predicting the success of PCD were calculated to be 75%and 65.4%respectively.CONCLUSION WBC and NLR can be used as simple tests for predicting response to PCD in patients with acute necrotizing pancreatitis. | Pankaj Gupta Gaurav Chayan Das Akash Bansal Jayanta Samanta Harshal S Mandavdhare Vishal Sharma Shano Naseem Vikas Gupta Thakur Deen Yadav Usha Dutta Neelam Varma Manavjit Singh Sandhu Rakesh Kochhar | 2022 | World Journal of Clinical Cases2022，10，1： | 1 |
| 10 | Polyisobutylene- anchored n-heterocyclic carbene ligands 显示文摘 | Chayanant H Su H L Hassan S B | 2009 | Org Lett2009，11，： | 1 |
| 11 | Administration-timedependent effects of olmesartan on the ambulatory blood pressure of essential hypertension patients显示文摘 | Hermida RC Ayala DE Chayan L | 2009 | Chronobiol Int2009，26，1： | 1 |
| 12 | Relationship between metabolic syndrome, circadian treatment time, and blood pressure non-dipping profile in essential hyper- tension显示文摘 | Hermida RC Chayan L Ayala DE | 2011 | Chronobiol Int2011，，6： | 1 |
| 13 | Administrationtime-de-pendent effects of olmesartan on the ambulatory blood pressure of es-sential hypertension patients显示文摘 | Hermida RC Ayala DE Chayan L | 2009 | Chronobiol Int2009，26，： | 1 |
| 14 | Relationship between metabolic syndrome, circadian treatment time, and blood pressure non-dipping profile in essential hypertension显示文摘 | Hermida RC Chayan L Ayala DE | 2011 | Chronobiol Int2011，28，6： | 1 |
| 15 | An Unusual Presentation of Cor pulmonale 显示文摘 | Atul Debbarma Swapan Sarkar Chayan Bhattacharjee | 2008 | Indian medical journal2008，102，7： | 1 |
| 16 | Association of metabolic syndrome and blood pressure nondipping profile in untreated hypertension显示文摘 | Hermida RC Chayan L Ayala DE | 2009 | Am J Hypertens2009，22，3： | 1 |
| 17 | Administration- time-dependent effects of olmesartan on the ambulatory blood pressure of essential hypertension patients 显示文摘 | Hermida RC Ayala DE Chayan L | 2009 | Chronobiol Int2009，26，1： | 1 |
| 18 | Administration-time- dependent effects of olmesartan on the ambulatory blood pressure of essential hypertension patients显示文摘 | Hermida RC Ayala DE Chayan L | 2009 | Chronobiol Int2009，26，1： | 1 |
| 19 | Megastigmane, aliphatic alcohol and benzoxazinoid glycosides from Acanthus ebracteatus 显示文摘 | Tripetch K Ryoji K Chayan P | 2001 | Phytochemistry2001，58，： | 1 |
| 20 | Administration-time-de- pendent effects of olmesartan on the ambulatory blood pressure ofessential hypertension patients 显示文摘 | Hermida RC Ayala DE Chayan L | 2009 | Chronobiol Int2009，26，1： | 1 |
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