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| 1 | Genome-level analysis of genetic regulation of liver gene expression networks显示文摘 | Gatti, D Maki, A Chesler, EJ Kirova, R Kosyk, O Lu, L Williams, RW Perkins, A Langston, MA Threadgill, DW Rusyn, I | 2007 | 中国生物学文摘2007，21，11： | 3 |
| 2 | 炎症状态下水肿与即早期和持续期痛行为之间的相关性分析:治疗意义探讨(英文)显示文摘迄今,有关个体的疼痛程度和炎症程度之间的精确关系一直存在争论,主要原因是缺乏能够同时反映多种痛(尤其是可鉴别疼痛即早期和持续期)的炎症模型以及定量方法的合理应用。因此,本研究在啮齿类动物评价了外周皮下组织致炎后炎症水肿与伤害性反应以及痛敏之间的相关性。为了更好地认识炎症特异性特征在治疗中的价值,我们对非甾体类抗炎药的作用效果也进行了评价。将一个剂量的蜜蜂毒(0.05mg/0.025ml)注入12个近交系(129P3/J、A/J、AKR/J、BALB/cJ、C3H/HeJ、C57BL/6J、C57BL/10J、C58/J、CBA/J、DBA/2J、RIIIS/J和SM/J)小鼠或6个剂量的蜜蜂毒(0.001、0.005、0.01、0.05、0.1、0.2mg/0.05ml)注入远交系(Sprague-Dawley)大鼠的一侧足底皮下,分别检测自发伤害性反应、热和机械性痛敏,以及炎症的水肿和局部皮温,然后对组间和组内数据进行相关性分析。此外,观察非甾体类抗炎药吲哚美辛对痛和炎症的作用效果。结果显示:(1)炎症水肿程度与注射侧自发缩足反射次数、舔足抬足时间等伤害性反射程度呈高度正相关(P≤0.003),而与热或机械性痛敏的程度没有相关性;(2)吲哚美辛(0.5、2.5、25mg/kg,i.p.,稀释于60%二甲基桠枫)可以剂量依赖性地抑制炎症水肿和自发伤害性反应,但是对热或机械性痛敏却只有在最高剂量下才有作用。这些结果提示,炎症水肿过程可能只参与动物受炎症刺激而引起的即早自发伤害性反应过程,而不参与与临床更加密切相关的痛敏过程。这个分析结果为确定抗炎治疗有益于缓解多种炎性痛中的哪个靶表证提供了一个有用的分析方法。 | William R. LARIVIERE Elissa J. CHESLER 李震 尚刚伟 陈亚宁 于耀清 吕卓敏 常莹 罗层 李开诚 陈军 | 2005 | 生理学报2005，57，3： | 2 |
| 3 | Nordihydroguaiaretic acid in- hibits insulin-like growth factor signaling, growth, and survival in human neuroblastoma ceils 显示文摘 | Meyer G E Chesler L Liu D | 2007 | Cell Biochem2007，102，6： | 1 |
| 4 | Mesenchymal stem cellsderived from adipose tissue vs bone marrow: in vitro comparison oftheir tropism towards gliomas 显示文摘 | Pendleton C Li Q Chesler DA | 2013 | PLoS One2013，8，58： | 1 |
| 5 | Metalloproteinase inhibition and erythroid potentiation are independent activities of tissue inhibitor of metalloproteinases-1显示文摘 | Chesler L Golde DW Bersch N | 1995 | Blood1995，86，12： | 1 |
| 6 | Proton release as a modulator of presynaptic function 显示文摘 | Traynelis SF Chesler M | 2001 | Neuron2001，32，6： | 1 |
| 7 | Quality of life in childhood cancer survivors显示文摘 | Zebrack BJ Chesler MA | 2002 | Psycho - Oncology2002，11，2： | 1 |
| 8 | Pulmonary vascular remodeling in isolated mouse lungs: effects on pulsatile pressure-flow relationships 显示文摘 | Tuchscherer HA Vanderpool RR Chesler NC | 2007 | J Biomech2007，40，5： | 1 |
| 9 | MR perfusion studies with T1-weighted echo planar imaging显示文摘 | Chesler DA Weisskoff RM | 1995 | Magn Reson Med1995，34，： | 1 |
| 10 | Collagen related gene and protein ex-pression changes in the lung in response to chronic hypoxia显示文摘 | Estrada KD Chesler NC | 2009 | Biomech Model Mechanobiol2009，8，4： | 1 |
| 11 | MR velocity imaging by phase display显示文摘 | Weeden VJ Rosen BR Chesler D | 1985 | J Comput Assist Tomogr1985，9，： | 1 |
| 12 | Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation显示文摘 | Kwong KK Belliveau JW Chesler DA | 1992 | Proceedings of the National Academy of Sciences of the United States of America1992，89，12： | 1 |
| 13 | Transmural pressure induces matrix-degrading activity in porcine arteries ex vivo显示文摘 | CHESLER N C KU D N GALIS Z S | 1999 | Am J Physiol1999，277，： | 1 |
| 14 | A psychometric analysis of the Quality of Life-Cancer Survivors (QOL-CS) in survivors of childhood cancer显示文摘 | ZEBRACK B J CHESLER M A | 2001 | Qual Life Res2001，10，4： | 1 |
| 15 | Fetal valproate syndrome:clinical and neuro developmental features in two sibling pairs 显示文摘 | Christianson AL Chesler N Kromberg JG | 1994 | Dev Med Child Neurol1994，36，4： | 1 |
| 16 | Dynamics of subdural hygroma following decompressive craniectomy:a comparative study显示文摘 | Aarabi B Chesler D Maulucci C | | 0，，06： | 1 |
| 17 | Density of organic matrix of native mineralized bone measured by water- and fat-suppressed proton projection MRI 显示文摘 | Wu Y Ackerman JL Chesler DA | 2003 | Magn Reson Med2003，50，1： | 1 |
| 18 | The meanoeortin-1 recep- tor gene mediates female-specific mechanisms of analgesia in mice and humans 显示文摘 | Mogil JS Wilson SG Chesler EJ | 2011 | Proe Natl Acad Sci USA2011，100，6： | 1 |
| 19 | Acute progesterone can recruit sex-specific neurochemical mechanisms mediating swim stress-induced and kappa-opioid analgesia in mice显示文摘 | Sternberg WF Chesler EJ Wilson SG | 2004 | Horm Behav2004，46，4： | 1 |
| 20 | Identification and Quanfitafion of Oxygenates in Gasoline Ampules Using Fourier Transform Near-Infrared and Fourier Transform Raman Spectroscopy显示文摘 | CHOQUETFE S J CHESLER S N DRENNEN J K | 1996 | Analytical Chemistry1996，68，20： | 1 |
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