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| 1 | High-resolution microendoscopy for esophageal cancer screening in China: A cost-effectiveness analysis显示文摘AIM:To study the cost-effectiveness of high-resolution microendoscopy(HRME)in an esophageal squamous cell carcinoma(ESCC)screening program in China.METHODS:A decision analytic Markov model of ESCC was developed.Separate model analyses were conducted for cohorts consisting of an averagerisk population or a high-risk population in China.Hypothetical 50-year-old individuals were followed until age 80 or death.We compared three different strategies for both cohorts:(1)no screening;(2)standard endoscopic screening with Lugol’s iodine staining;and(3)endoscopic screening with Lugol’s iodine staining and an HRME.Model parameters were estimated from the literature as well as from GLOBOCAN,the Cancer Incidence and Mortality Worldwide cancer database.Health states in the model included non-neoplasia,mild dysplasia,moderate dysplasia,high-grade dysplasia,intramucosal carcinoma,operable cancer,inoperable cancer,and death.Separate ESCC incidence transition rates were generated for the average-risk and high-risk populations.Costs in Chinese currency were converted to international dollars(I$)and were adjusted to 2012dollars using the Consumer Price Index.RESULTS:The main outcome measurements for this study were quality-adjusted life years(QALYs)and incremental cost-effectiveness ratio(ICER).For the average-risk population,the HRME screening strategy produced 0.043 more QALYs than the no screening strategy at an additional cost of I$646,resulting in an ICER of I$11808 per QALY gained.Standard endoscopic screening was weakly dominated.Among the high-risk population,when the HRME screening strategy was compared with the standard screening strategy,the ICER was I$8173 per QALY.For both the high-risk and average-risk screening populations,the HRME screening strategy appeared to be the most cost-effective strategy,producing ICERs below the willingness-topay threshold,I$23500 per QALY.One-way sensitivity analysis showed that,for the average-risk population,higher specificity of Lugol’s iodine(>40%)and lower specificity of HRME(<70%)could make Lugol’s iodine screening cost-effective.For the high-risk population,the results of the model were not substantially affected by varying the follow-up rate after Lugol’s iodine screening,Lugol’s iodine test characteristics(sensitivity and specificity),or HRME specificity.CONCLUSION:The incorporation of HRME into an ESCC screening program could be cost-effective in China.Larger studies of HRME performance are needed to confirm these findings. | Chin Hur Sung Eun Choi Chung Yin Kong Gui-Qi Wang Hong Xu Alexandros D Polydorides Li-Yan Xue Katherine E Perzan Angela C Tramontano Rebecca R Richards-Kortum Sharmila Anandasabapathy | 2015 | World Journal of Gastroenterology2015,21,18: | 8 |
| 2 | Perceptions of wood in rivers and challenges for stream restoration in the United States显示文摘 | Anne Chin Melinda D Daniels Michael A Urban | 2008 | Environmental Management2008,41,6: | 1 |
| 3 | Evaluation of surface compo- nents of Brucella ovis as antigens for the detection of preeipitin antibody in serums from artificially exposed rams显示文摘 | Chin J C Plant J W Claxton P D | 1983 | Aust Vet J1983,60,: | 1 |
| 4 | Reduced spinal bone mineral density in adolescents of an Ultra - Orthodox Jewish community in Brooklyn 显示文摘 | Taha W Chin D Silverberg Al | 2001 | Pediatrics2001,107,: | 1 |
| 5 | ACC /AHA guidelines for the evaluation and management of chronic heart failure in the adult:executive summary:a report of the American College of Cardiology/American Heart Association task force on practice guidelines(committee to revise the 1995 guidelines for the evaluation and management of heart failure)显示文摘 | HUNT S A BAKER D W CHIN M H | 2001 | Circulation2001,104,: | 1 |
| 6 | ACC/AHA Guidelines for the Evaluation and Management of Chronic Heart Failure in the Aduh: Executive Summary A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Revise the 1995 Guidelines for the Evaluation and Management of Heart Failure): Developed in Collaboration with the International Society for Heart and Lung Transplantation; Endorsed by the Heart Failure Society of America 显示文摘 | HUNT S A BAKER D W CHIN M H | 2001 | Circulation2001,104,24: | 1 |
| 7 | Traffic responsive signal timing forsystem - wide traffic control显示文摘 | Spall J C Chin D C | 1997 | Transportation ResearchPart C :Emerging Technologies1997,5,3: | 1 |
| 8 | Simuhaneously fitting and segmenting multiple-structure data with outliers显示文摘 | Wang H Chin T J Surer D | 2012 | Pat- tern Analysis and Machine Intelligence IEEE Transac- tions on2012,34,6: | 1 |
| 9 | Thetwo-component sensor kinase KdpD is required forSalmonella typhimurium colonization ofCaenorhabditis elegans and survival in macrophages显示文摘 | Alegado R A Chin C Y Monack D M | 2011 | Cellular Microbiology2011,13,10: | 1 |
| 10 | Metal distribution in jet plating显示文摘 | Karakur C Chin D T | | J Electrochem Soc0,141,3: | 1 |
| 11 | Nociceptin/Orphanin FQ modulation of ionic conductances in rat basal forebrain neurons显示文摘 | Chin J H Harris K MacTavish D | 2002 | J Pharmacol Exp Ther2002,303,1: | 1 |
| 12 | Head and neck cancer:past, present and future 显示文摘 | Chin D Boyle GM Porceddu S | 2006 | Expert Rev Anticancer Ther2006,6,7: | 1 |
| 13 | Evaluation of seven media for micro propagation of high bush blueberry显示文摘 | Wolfe D E ECK P Chin C K | 1983 | Hori Science1983,18,: | 1 |
| 14 | Corrosion Electrochemical Behavior of Epoxy Anticorrosive Paints Based on Zinc Molybdenum Phosphate and Zinc Oxide显示文摘 | Veleva L Chin J Amo B D | 1999 | Progress in Organic Coatings1999,,04: | 1 |
| 15 | Relationship of ozone and carbon monoxide over North America 显示文摘 | CHIN M JACOB D J MUNGER J W | 1994 | J Geophys Res1994,99,14: | 1 |
| 16 | Student-Generated Questions: A Meaningful Aspect of Learning in Science 显示文摘 | Chin C Brown D E | 2002 | In- ternational Journal of Science Education2002,24,5: | 1 |
| 17 | A onepass thinning algorithm and its parallel implementation显示文摘 | CHIN R T WAN G H K Stover D L | 1987 | Computer Vision Graphics Image Process-ing1987,40,1: | 1 |
| 18 | Differential effects of cannabinoid receptor agonists on regional brain activity using pharmacological MRI显示文摘 | Chin C L Tovcimak A E Hradil V P Seifert T R Hollingsworth P R Chandran P Zhu C Z Gauvin D Pai M Wetter J Hsieh G C Honore P Frost J M Dart M J Meyer M D Yao B B Cox B F Fox G B | | 0,,02: | 1 |
| 19 | Randomized,controlled trial of intramuscular or intracoronary injection of autologous bone marrow cells into scarred myocardium during CABG versus CABG alone显示文摘 | Ang KL Chin D Leyva F | | 0,,10: | 1 |
| 20 | Novel markers for poor prognosis in head and neck cancer显示文摘 | Chin D Boyle GM Williams RM | 2005 | IntJ Cancer2005,113,5: | 1 |