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| 1 | Randomised controlled trial comparing modified Sano's and narrow band imaging international colorectal endoscopic classifications for colorectal lesions显示文摘AIM To assess the utility of modified Sano′s(MS) vs thenarrow band imaging international colorectal endoscopic(NICE) classification in differentiating colorectal polyps.METHODS Patients undergoing colonoscopy between 2013 and 2015 were enrolled in this trial.Based on the MS or the NICE classifications,patients were randomised for real-time endoscopic diagnosis.This was followed by biopsies,endoscopic or surgical resection.The endoscopic diagnosis was then compared to the final(blinded) histopathology.The primary endpoint was the sensitivity(Sn),specificity(Sp),positive predictive value(PPV) and negative predictive value(NPV) of differentiating neoplastic and non-neoplastic polyps(MSⅡ/Ⅱo/Ⅲa/Ⅲb vs I or NICE 1 vs 2/3).The secondary endpoints were 'endoscopic resectability'(MSⅡ/Ⅱo/Ⅲa vs Ⅰ/Ⅲb or NICE 2 vs 1/3),NPV for diminutive distal adenomas and prediction of post-polypectomy surveillance intervals.RESULTS A total of 348 patients were evaluated.The Sn,Sp,PPV and NPV in differentiating neoplastic polyps from non-neoplastic polyps were,98.9%,85.7%,98.2% and 90.9% for MS;and 99.1%,57.7%,95.4% and 88.2% for NICE,respectively.The area under the receiver operating characteristic curve(AUC) for MS was 0.92(95%CI:0.86-0.98);and AUC for NICE was 0.78(95%CI:0.69,0.88).The Sn,Sp,PPV and NPV in predicting 'endoscopic resectability' were 98.9%,86.1%,97.8% and 92.5% for MS;and 98.6%,66.7%,94.7% and 88.9% for NICE,respectively.The AUC for MS was 0.92(95%CI:0.87-0.98);and the AUC for NICE was 0.83(95%CI:0.75-0.90).The AUC values were statistically different for both comparisons(P = 0.0165 and P = 0.0420,respectively).The accuracy for diagnosis of sessile serrated adenoma/polyp(SSA/P) with high confidence utilizing MS classification was 93.2%.The differentiation of SSA/P from other lesions achieved Sp,Sn,PPV and NPV of 87.2%,91.5%,89.6% and 98.6%,respectively.The NPV for predicting adenomas in diminutive rectosigmoid polyps(n = 150) was 96.6% and 95% with MS and NICE respectively.The calculated accuracy of post-polypectomy surveillance for MS group was 98.2%(167 out of 170) and for NICE group was 92.1%(139 out of 151).CONCLUSION The MS classification outperformed the NICE classification in differentiating neoplastic polyps and predicting endoscopic resectability.Both classifications met ASGE PIVI thresholds. | Leonardo Zorrón Cheng Tao Pu Kuan Loong Cheong Doreen Siew Ching Koay Sze Pheh Yeap Amanda Ovenden Mahima Raju Andrew Ruszkiewicz Philip W Chiu James Y Lau Rajvinder Singh | 2018 | World Journal of Gastrointestinal Endoscopy2018，10，9： | 4 |
| 2 | Effects of the phase-separated melt on crystallization behavior and morphology in short chain branched metallocene polyethylenes显示文摘 | Fu Q Chiu F C McCreight K W Guo M Tseng W W Cheng S Z Keating M Y Hsieh E T and DesLauriers P J | | 0，，： | 2 |
| 3 | Cancer Genome Scanning in Plasma: Detection of Tumor-Associated Copy Number Aberrations, Single-Nucleotide Variants, and Tumoral Heterogeneity by Massively Parallel Sequencing显示文摘 | Chan K C Allen Jiang Peiyong Zheng Yama W L Liao Gary J W Sun Hao Wong John Siu Shing Shun N Chan Wing C Chan Stephen L Chan Anthony T C Lai Paul B S Chiu Rossa W K Lo Y M D | 2013 | Clinical Chemistry2013，，1： | 2 |
| 4 | Hydrogen effect on the cavitation erosion resistance of AISI 316L stainless steel laser surface modified with NiTi显示文摘 | Chiu K Y C F T Man H C | 2007 | Materials Letters2007，61，1： | 1 |
| 5 | Modeling no-notice mass evacuation using a dynamic traffic flow optimization model显示文摘 | Chiu Y Zheng H Villalobos J | 2007 | IIE Transactions2007，39，1： | 1 |
| 6 | Predictors for extraintestinal infectiom of non-typhoidal Salmonella in patients without AIDS 显示文摘 | Chiu C H Lin T Y Qu J T | 1999 | Hat J Clin Pract1999，53，： | 1 |
| 7 | The response of skin disease to stress:changes in the severity of acne vulgaris as affected by examination stress显示文摘 | Susna Y chon Alexa B | 2003 | J Arch Dematol2003，139，： | 1 |
| 8 | Origin of Field-Dependent Optical Transmission of Magnetic Fluid Films显示文摘 | Chiu Y P Jeang B Y | 2001 | Applied Physics Letters2001，79，： | 1 |
| 9 | Computed tomography angiography imaging for the chimeric anterolateral thigh flap in reconstruction of full thickness buccal defect显示文摘 | CHIU W K LIN W C CHEN S Y | 2011 | ANZ J Surg2011，81，3： | 1 |
| 10 | A near-optimal sensor placement algorithm to achieve complete coverage/discrimination in sensor networks显示文摘 | F Y S Lin P L Chiu | 2005 | IEEE Communications Letters2005，9，1： | 1 |
| 11 | In vitro neutralization by monoclonal antibodies against yellow grouper nervous necrosis virus(YGNNV) and immunolocalization of viru infection in yellow grouper,Epinephelus awoara (Temminck & Schlegel)显示文摘 | Lai Y S Chiu H C Murali S | 2001 | J Fish Dis2001，24，： | 1 |
| 12 | Bidirectional regulation of neuronal nitric-oxide synthase phosphorylation at serine 847 by the N-methyl-D-aspartate receptor显示文摘 | RAMEAU G A CHIU L Y ZIFF E B | 2004 | J Biol Chem2004，279，14： | 1 |
| 13 | Modeling ozonation process with pollutant in a rotating packed bed显示文摘 | Chen Y H Chiu C Y Chang C Y | 2005 | Ind Eng Chem Res2005，44，1： | 1 |
| 14 | Gender differs: assessing a model of online purchase intentions in e-tail service 显示文摘 | Chiu Y B Lin C P Tang L L | 2005 | Inernational Journal of Service Industry Management2005，16，41： | 1 |
| 15 | Volume fractions of silver-coated copper powders in conductive adhesives for microelectronic applications 显示文摘 | LIN Y S CHIU S S | 2004 | Polym Eng Sci2004，44，11： | 1 |
| 16 | A sensitive and robust method for the determination of alkylphenol polyethoxylates and their carboxylic acids and their transformation in a trickling filter wastewater treatment plant显示文摘 | Koh Y K K Chiu T Y Boobis A R Cartmell E Pollard S J T Scrimshaw M D I_ester J N | 2008 | Chemosphere2008，73，4： | 1 |
| 17 | Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma显示文摘 | Chiu RW Chan KC Gao Y etal | 2008 | Proc Natl Aead Sci U S A2008，105，20： | 1 |
| 18 | Effectiveness observed by passengers taking the Taiwan high speed railway service: Especially their observation of overall quality and satisfaction显示文摘 | Chiu C H Chen H Y Liang C H | 2012 | Advanced Material Research2012，555，： | 1 |
| 19 | Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in matemal plasma显示文摘 | Chiu RW Chan KC Gao Y | | 0，，： | 1 |
| 20 | Relationship Marketing and Consumer Switching Behavior显示文摘 | Chiu H C Hsieh Y C Li Y C | 2005 | Journal of Business Research2005，58，12： | 1 |
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