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| 1 | Fecal Microbiome and Volatile Organic Compound Metabolome in Obese Humans With Nonalcoholic Fatty Liver Disease显示文摘 | Maitreyi Raman Iftikhar Ahmed Patrick M. Gillevet Chris S. Probert Norman M. Ratcliffe Steve Smith Rosemary Greenwood Masoumeh Sikaroodi Victor Lam Pam Crotty Jennifer Bailey Robert P. Myers Kevin P. Rioux | 2013 | Clinical Gastroenterology and Hepatology2013，，7： | 5 |
| 2 | 卫生技术评估:全球经验综述显示文摘一、《健康价值》特刊中的卫生技术评估综述近来,在药物发展和卫生管理领域中,卫生技术评估(Health Technology Assessment,HTA)引发了较多的关注和争议。这是由于HTA带来的高风险收益引起了人们的兴趣。对HTA结果的理解很大程度上取决于各主体的视角。评论家认为,目前HTA的应用还仅限于对新医疗技术进行评估以设置其使用上的限制,但更应提倡运用HTA技术达到促进资源的有效配置及改善群体健康的目的。 | John C.O'Donnell PhD Sissi V.Pham PharmD Chris L.Pashos DavidW.Miller Marilyn Dix Smith BPharm 刘庆婧 吴晶 | 2010 | 中国药物经济学2010，，1： | 4 |
| 3 | Mediastinal node staging by positron emission tomographycomputed tomography and selective endoscopic ultrasound with fine needle aspiration for patients with upper gastrointestinal cancer:Results from a regional centre显示文摘AIM To investigate the impact of endoscopic ultrasound-guided fine-needle aspiration(EUS-FNA) and positron emission tomography-computed tomography(PET-CT) in the nodal staging of upper gastrointestinal(GI) cancer in a tertiary referral centre.METHODS We performed a retrospective review of prospectively recorded data held on all patients with a diagnosis of upper GI cancer made between January 2009 and December 2015. Only those patients who had both a PET-CT and EUS with FNA sampling of a mediastinal node distant from the primary tumour were included. Using a positive EUS-FNA result as the gold standard for lymph node involvement, the sensitivity, specificity, positive and negative predictive values(PPV and NPV) and accuracy of PET-CT in the staging of mediastinal lymph nodes were calculated. The impact on therapeutic strategy of adding EUS-FNA to PET-CT was assessed.RESULTS One hundred and twenty one patients were included. Sixty nine patients had a diagnosis of oesophageal adenocarcinoma(Thirty one of whom were junctional), forty eight had oesophageal squamous cell carcinoma and four had gastric adenocarcinoma. The FNA results were inadequate in eleven cases and the PET-CT findings were indeterminate in two cases, therefore thirteen patients(10.7%) were excluded from further analysis. There was concordance between PET-CT and EUS-FNA findings in seventy one of the remaining one hundred and eight patients(65.7%). The sensitivity, specificity, PPV and NPV values of PET-CT were 92.5%, 50%, 52.1% and 91.9% respectively. There was discordance between PET-CT and EUS-FNA findings in thirty seven out of one hundred and eight patients(34.3%). MDT discussion led to a radical treatment pathway in twenty seven of these cases, after the final tumour stage was altered as a direct consequence of the EUS-FNA findings. Of these patients, fourteen(51.9%) experienced clinical remission of a median of nine months(range three to forty two months). CONCLUSION EUS-FNA leads to altered staging of upper GI cancer, resulting in more patients receiving radical treatment that would have been the case using PET-CT staging alone. | Chris Harrington Lyn Smith Jennifer Bisland Elisabet López González Neil Jamieson Stuart Paterson Adrian John Stanley | 2018 | World Journal of Gastrointestinal Endoscopy2018，10，1： | 4 |
| 4 | Pushing the boundaries of diode-pumped solid-state lasers for high-energy applications显示文摘We report on the successful demonstration of a 150 J nanosecond pulsed cryogenic gas cooled,diode-pumped multi-slab Yb:YAG laser operating at 1 Hz.To the best of our knowledge,this is the highest energy ever recorded for a diodepumped laser system. | Saumyabrata Banerjee Paul Mason Jonathan Phillips Jodie Smith Thomas Butcher Jacob Spear Mariastefania De Vido Gary Quinn Danielle Clarke Klaus Ertel Cristina Hernez-Gomez Chris Edwards John Collier | 2020 | High Power Laser Science and Engineering2020，8，2： | 4 |
| 5 | Development of a 100 J,10 Hz laser for compression experiments at the High Energy Density instrument at the European XFEL显示文摘In this paper we review the design and development of a 100 J, 10 Hz nanosecond pulsed laser, codenamed DiPOLE100 X,being built at the Central Laser Facility(CLF). This 1 kW average power diode-pumped solid-state laser(DPSSL) is based on a master oscillator power amplifier(MOPA) design, which includes two cryogenic gas cooled amplifier stages based on DiPOLE multi-slab ceramic Yb:YAG amplifier technology developed at the CLF. The laser will produce pulses between 2 and 15 ns in duration with precise, arbitrarily selectable shapes, at pulse repetition rates up to 10 Hz, allowing real-time shape optimization for compression experiments. Once completed, the laser will be delivered to the European X-ray Free Electron Laser(XFEL) facility in Germany as a UK-funded contribution in kind, where it will be used to study extreme states of matter at the High Energy Density(HED) instrument. | Paul Mason Saumyabrata Banerjee Jodie Smith Thomas Butcher Jonathan Phillips Hauke Hoppner Dominik Moller Klaus Ertel Mariastefania De Vido Ian Hollingham ANDrew Norton Stephanie Tomlinson Tinesimba Zata Jorge Suarez Merchan Chris Hooker Mike Tyldesley Toma Toncian Cristina HernANDez-Gomez Chris Edwards John Collier | 2018 | High Power Laser Science and Engineering2018，6，4： | 4 |
| 6 | Seasonal Forecasts of the Summer 2016 Yangtze River Basin Rainfall显示文摘The Yangtze River has been subject to heavy flooding throughout history,and in recent times severe floods such as those in 1998 have resulted in heavy loss of life and livelihoods.Dams along the river help to manage flood waters,and are important sources of electricity for the region.Being able to forecast high-impact events at long lead times therefore has enormous potential benefit.Recent improvements in seasonal forecasting mean that dynamical climate models can start to be used directly for operational services.The teleconnection from El Ni ?no to Yangtze River basin rainfall meant that the strong El Ni ?no in winter 2015/16 provided a valuable opportunity to test the application of a dynamical forecast system.This paper therefore presents a case study of a real-time seasonal forecast for the Yangtze River basin,building on previous work demonstrating the retrospective skill of such a forecast.A simple forecasting methodology is presented,in which the forecast probabilities are derived from the historical relationship between hindcast and observations.Its performance for2016 is discussed.The heavy rainfall in the May–June–July period was correctly forecast well in advance.August saw anomalously low rainfall,and the forecasts for the June–July–August period correctly showed closer to average levels.The forecasts contributed to the confidence of decision-makers across the Yangtze River basin.Trials of climate services such as this help to promote appropriate use of seasonal forecasts,and highlight areas for future improvements. | Philip E. BETT Adam A. SCAIFE Chaofan LI Chris HEWITT Nicola GOLDING Peiqun ZHANG Nick DUNSTONE Doug M. SMITH Hazel E. THORNTON Riyu LU Hong-Li REN | 2018 | Advances in Atmospheric Sciences2018，35，8： | 3 |
| 7 | If Smallpox Strikes Portland显示文摘 | Chris L Barrett Sphen G Eubank James P Smith | 2005 | Scientific American (S0036-8733)2005，292，3： | 1 |
| 8 | Problem-based learning显示文摘 | Chris Smith | 2000 | Biochemical Education2000，，3： | 1 |
| 9 | Flow batteries for enhancing wind power integration显示文摘 | Banham-Hall D D Taylor G A Smith Chris A | 2012 | IEEE Transactions on Power Systems2012，27，3： | 1 |
| 10 | If Smallpox Strikes Portland 显示文摘 | Chris L Barrett Sphen G Eubank James P Smith | 2005 | Scientific American (S0036-8733)2005，292，3： | 1 |
| 11 | The Effect of an Organizational Net- work for Patient Safety on Safety Event Repor- ting显示文摘 | Lianne Jeffs Chris Hayes Orla Smith | 2014 | The Effect of anOrganizational Network for Patient Safety on Safety Event Reporting2014，37，3： | 1 |
| 12 | The efficacy of cognitive-behavioral therapy for insomnia in patients with chronic pain显示文摘 | Carla R. Jungquist Chris O’Brien Sara Matteson-Rusby Michael T. Smith Wilfred R. Pigeon Yinglin Xia Naiji Lu Michael L. Perlis | 2010 | Sleep Medicine2010，，3： | 1 |
| 13 | Constraint satisfaction problems:algorithm and appli- cations 显示文摘 | BRAILSFORD Sally C POTTS Chris N SMITH Barbara M | 1999 | European Journal of Operational Research1999，119，3： | 1 |
| 14 | Crustins: Enigmatic WAP domain-containing antibacterial proteins from crustaceans显示文摘 | Valerie J. Smith Jorge M.O. Fernandes Graham D. Kemp Chris Hauton | 2008 | Developmental and Comparative Immunology2008，，7： | 1 |
| 15 | Exposure to commonly prescribed drugs and the etiology of cryptogenic fibrosing alvcolitis显示文摘 | Richard Hubbard Anorea Vernn Chris Smith et al | 1998 | Am J Respir Crit Care Med1998，175，31： | 1 |
| 16 | If Smallpox Strikes Portland 显示文摘 | Chris L Barrett Sphen G Eubank James P Smith | 2005 | Scientific American (S0036-8733)2005，292，3： | 1 |
| 17 | The new face of bioplastics 显示文摘 | Chris Smith | 2008 | European Plastics News2008，，3： | 1 |
| 18 | Problem-based learning显示文摘 | Chris Smith | 2000 | Biochemical Education2000，，3： | 1 |
| 19 | Children with early-onset inflammatory bowel disease (IBD): Analysis of a pediatric IBD consortium registry显示文摘 | Melvin B. Heyman Barbara S. Kirschner Benjamin D. Gold George Ferry Robert Baldassano Stanley A. Cohen Harland S. Winter Patricia Fain Chris King Terry Smith Hashem B. El-Serag | 2005 | The Journal of Pediatrics2005，，1： | 1 |
| 20 | Spectral line parameters including temperature dependences of self- and air-broadening in the 2←0 band of CO at 2.3μm显示文摘 | V. Malathy Devi D. Chris Benner M.A.H. Smith A.W. Mantz K. Sung L.R. Brown A. Predoi-Cross | 2012 | Journal of Quantitative Spectroscopy and Radiative Transfer2012，，： | 1 |
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