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| 1 | Burden of valvular heart diseases: a population-based study显示文摘 | Vuyisile T Nkomo Julius M Gardin Thomas N Skelton John S Gottdiener Christopher G Scott Maurice Enriquez-Sarano | 2006 | The Lancet . 2006 (9540)2006,,: | 1 |
| 2 | Cystatin C:an improved estimator of glomerular filtration rate显示文摘 | Omar F Laterza Christopher P Mitchell G Scott | 2002 | Clinical Chemistry2002,48,5: | 1 |
| 3 | Feasibility of pancreatectomy following high-dose proton therapy for unresectable pancreatic cancer显示文摘AIM To review surgical outcomes for patients undergoing pancreatectomy after proton therapy with concomitant capecitabine for initially unresectable pancreatic adenocarcinoma.METHODS From April 2010 to September 2013,15 patients with initially unresectable pancreatic cancer were treated withproton therapy with concomitant capecitabine at 1000 mg orally twice daily. All patients received 59.40 Gy(RBE) to the gross disease and 1 patient received 50.40 Gy(RBE) to high-risk nodal targets. There were no treatment interruptions and no chemotherapy dose reductions. Six patients achieved a radiographic response sufficient to justify surgical exploration,of whom 1 was identified as having intraperitoneal dissemination at the time of surgery and the planned pancreatectomy was aborted. Five patients underwent resection. Procedures included:Laparoscopic standard pancreaticoduodenectomy(n = 3),open pyloris-sparing pancreaticoduodenectomy(n = 1),and open distal pancreatectomy with irreversible electroporation(IRE) of a pancreatic head mass(n = 1). RESULTS The median patient age was 60 years(range,51-67). The median duration of surgery was 419 min(range,290-484),with a median estimated blood loss of 850 cm^3(range,300-2000),median ICU stay of 1 d(range,0-2),and median hospital stay of 10 d(range,5-14). Three patients were re-admitted to a hospital within 30 d after discharge for wound infection(n = 1),delayed gastric emptying(n = 1),and ischemic gastritis(n = 1). Two patients underwent R0 resections and demonstrated minimal residual disease in the final pathology specimen. One patient,after negative pancreatic head biopsies,underwent IRE followed by distal pancreatectomy with no tumor seen in the specimen. Two patients underwent R2 resections. Only 1 patient demonstrated ultimate local progression at the primary site. Median survival for the 5 resected patients was 24 mo(range,10-30).CONCLUSION Pancreatic resection for patients with initially unresectable cancers is feasible after high-dose [59.4 Gy(RBE)] proton radiotherapy with a high rate of local control,acceptable surgical morbidity,and a median survival of 24 mo. | Kathryn E Hitchcock R Charles Nichols Christopher G Morris Debashish Bose Steven J Hughes John A Stauffer Scott A Celinski Elizabeth A Johnson Robert A Zaiden Nancy P Mendenhall Michael S Rutenberg | 2017 | World Journal of Gastrointestinal Surgery2017,9,4: | 1 |
| 4 | Estimation of kerogen porosity in source rocks as a function of thermal transformation:Example from the Mowry Shale in the Powder River Basin of Wyoming 显示文摘 | Christopher J M Scott G L | 2012 | AAPG Bulletin2012,96,1: | 1 |
| 5 | Burden of valvular heart diseases: a population-based study显示文摘 | Vuyisile T Nkomo Julius M Gardin Thomas N Skelton John S Gottdiener Christopher G Scott Maurice Enriquez-Sarano | 2006 | 2006 (9540)2006,,9540: | 1 |
| 6 | Biodiesel from algae: challenges and prospects显示文摘 | Stuart A Scott Matthew P Davey John S Dennis Irmtraud Horst Christopher J Howe David J Lea-Smith Alison G Smith | 2010 | Current Opinion in Biotechnology2010,,3: | 1 |
| 7 | Burden of valvular heart diseases: a population-based study显示文摘 | Vuyisile T Nkomo Julius M Gardin Thomas N Skelton John S Gottdiener Christopher G Scott Maurice Enriquez-Sarano | 2006 | The Lancet2006,,9540: | 1 |
| 8 | Biodiesel from algae: challenges and prospects显示文摘 | Stuart A Scott Matthew P Davey John S Dennis Irmtraud Horst Christopher J Howe David J Lea-Smith Alison G Smith | 2010 | Current Opinion in Biotechnology2010,,3: | 1 |
| 9 | Remote electrocardiograph monitoring using a novel adhesive strip sensor: A pilot study显示文摘The increase in health care costs is not sustainable and has heightened the need for innovative low cost effective strategies for delivering patient care. Remote monitoring holds great promise for preventing or shortening duration of hospitalization even while improving quality of care. We therefore conducted a proof of concept study to examine the quality of electrocardiograph(ECG) recordings obtained remotely and to test its potential utility in detecting harmful rhythms such as atrial fibrillation. We tested a novel adhesive strip ECG monitor and assessed the ECG quality in ambulatory individuals. 2630 ECG strips were analyzed and classified as: Sinus, atrial fibrillation(AF), indeterminate, or other. Four readers independently rated ECG quality: 0: Noise; 1: QRS complexes seen, but P-wave indeterminate; 2: QRS complexes seen, P-waves seen but poor quality; and 3: Clean QRS complexes and P-waves. The combined average rating was: Noise 12%; R-R, no P-wave 10%; R-R, no PR interval 18%; and R-R with PR interval 60%(if Sinus). If minimum diagnostic quality was a score of 1, 88% of strips were diagnostic. There was moderate to high agreement regarding quality(weighted Kappa statistic values; 0.58 to 0.76) and high level of agreement regarding ECG diagnosis(ICC = 0.93). A highly variable RR interval(HRV ≥ 7) predicted AF(AUC = 0.87). The monitor acquires and transmits diagnostic high quality ECG data and permits characterization of AF. | Charles J Bruce Dorothy J Ladewig Virend K Somers Kevin E Bennet Scott Burrichter Christopher G Scott Lyle J Olson Paul A Friedman | 2016 | World Journal of Cardiology2016,8,10: | 0 |