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| 1 | Perioperative fluid management in major hepatic resection: an integrative review显示文摘BACKGROUND: Fluid intervention and vasoactive pharmacological support during hepatic resection depend on the preference of the attending clinician, institutional resources, and practice culture. Evidence-based recommendations to guide perioperative fluid management are currently limited. Therefore, we provide a contemporary clinical integrative overview of the fundamental principles underpinning fluid intervention and hemodynamic optimization for adult patients undergoing major hepatic resection. DATA SOURCES: A literature review was performed of MEDLINE, EMBASE and the Cochrane Central Registry of Controlled Trials using the terms 'surgery', 'anesthesia', 'starch', 'hydroxyethyl starch derivatives', 'albumin', 'gelatin', 'liver resection', 'hepatic resection', 'fluids', 'fluid therapy', 'crystalloid', 'colloid', 'saline', 'plasma-Lyte', 'plasmalyte', 'hartmann's', 'acetate', and 'lactate'. Search results for MEDLINE and EMBASE were additionally limited to studies on human populations that included adult age groups and publications in English. RESULTS: A total of 113 articles were included after appropriate inclusion criteria screening. Perioperative fluid management as it relates to various anesthetic and surgical techniques is discussed.CONCLUSIONS: Clinicians should have a fundamental understanding of the surgical phases of the resection, hemodynamic goals, and anesthesia challenges in attempts to individualize therapy to the patient's underlying pathophysiological condition. Therefore, an ideal approach for perioperative fluid therapy is always individualized. Planning and designing large-scale clinical trials are imperative to define the optimal type and amount of fluid for patients undergoing major hepatic resection. Further clinical trials evaluating different intraoperative goal-directed strategies are also eagerly awaited. | Osamu Yoshino Marcos Vinicius Perini Christopher Christophi Laurence Weinberg | 2017 | Hepatobiliary & Pancreatic Diseases International2017，16，5： | 5 |
| 2 | Posthepatectomy liver failure: A definition and grading by the International Study Group of Liver Surgery (ISGLS)显示文摘 | Nuh N. Rahbari O. James Garden Robert Padbury Mark Brooke-Smith Michael Crawford Rene Adam Moritz Koch Masatoshi Makuuchi Ronald P. Dematteo Christopher Christophi Simon Banting Val Usatoff Masato Nagino Guy Maddern Thomas J. Hugh Jean-Nicolas Vauthey Pau | 2011 | Surgery2011，，5： | 4 |
| 3 | From minimal to maximal surgery in the treatment of hepatocarcinoma:A review显示文摘Hepatocellular carcinoma represents one of the most challenging frontiers in liver surgery. Surgeons have to face a broad spectrum of aspects,from the underlying liver disease to the new surgical techniques. Safe liver resection can be performed in patients with portal hypertension and well-compensated liver function witha 5-year survival rate of 50%,offering good longterms results in selected patients. With the advances in laparoscopic surgery,major liver resections can be performed with minimal harm,avoiding the wound and leak complications related to the laparotomies. Studies have shown that oncological margins are the same as in open surgery. In patients submitted to liver resection(either laparoscopic or open) who experience recurrence,re-resection or salvage liver transplantation has been showing to be an alternative approach in well selected cases. The decision making approach to the cirrhotic patient is becoming more complex and should involve hepatologists,liver surgeons,radiologists and oncologists. Better understanding of the different risk factors for recurrence and survival should be aimed in these multidisciplinary discussions. We here in discuss the hot topics related to surgical risk factors regarding the surgical treatment of hepatocellular carcinoma: anatomical resection,margin status,macrovascular tumor invasion,the place of laparoscopy,salvage liver transplantation and liver transplantation. | Marcos Vinicius Perini Graham Starkey Michael A Fink Ramesh Bhandari Vijayaragavan Muralidharan Robert Jones Christopher Christophi | 2015 | World Journal of Hepatology2015，7，1： | 4 |
| 4 | Posthepatectomy liver failure: A definition and grading by the International Study Group of Liver Surgery (ISGLS)显示文摘 | Nuh N. Rahbari O. James Garden Robert Padbury Mark Brooke-Smith Michael Crawford Rene Adam Moritz Koch Masatoshi Makuuchi Ronald P. Dematteo Christopher Christophi Simon Banting Val Usatoff Masato Nagino Guy Maddern Thomas J. Hugh Jean-Nicolas Vauthey Pau | 2011 | Surgery2011，，5： | 2 |
| 5 | Bile leakage after hepatobiliary and pancreatic surgery: A definition and grading of severity by the International Study Group of Liver Surgery显示文摘 | Moritz Koch O. James Garden Robert Padbury Nuh N. Rahbari Rene Adam Lorenzo Capussotti Sheung Tat Fan Yukihiro Yokoyama Michael Crawford Masatoshi Makuuchi Christopher Christophi Simon Banting Mark Brooke-Smith Val Usatoff Masato Nagino Guy Maddern Thomas | 2011 | Surgery2011，，5： | 2 |
| 6 | Bile leakage after hepatobiliary and pancreatic surgery: A definition and grading of severity by the International Study Group of Liver Surgery显示文摘 | Moritz Koch O. James Garden Robert Padbury Nuh N. Rahbari Rene Adam Lorenzo Capussotti Sheung Tat Fan Yukihiro Yokoyama Michael Crawford Masatoshi Makuuchi Christopher Christophi Simon Banting Mark Brooke-Smith Val Usatoff Masato Nagino Guy Maddern Thomas | 2011 | Surgery2011，，5： | 2 |
| 7 | Prevention of diabetes in women with a history of gestational diabetes: effects of metformin and lifestyle interventions 显示文摘 | Ratner RE Christophi CA Metzger BE | 2008 | J Clin Endocrinol Metab2008，93，12： | 1 |
| 8 | Distribution and deteminants of very low levels of cardiac troponin T in patients with stable coronary artery disease显示文摘 | Omland T De Lemos JA Christophi C | | 0，，202： | 1 |
| 9 | The renin-angiotensin system and malignancy显示文摘 | Ager EI Neo J Christophi C | 2008 | Carcinogenesis2008，29，9： | 1 |
| 10 | Association of diabetes mellitus and pancreatic adenocarcinoma:a meta-analysis of 88 studies显示文摘 | Batabyal P Vander Hoom S Christophi C | 2014 | Ann Surg Oncol2014，21，7： | 1 |
| 11 | Distinct pro-moters regulate tissue-specific and differential expressionof kallikrein 6 in CNS demyelinating disease显示文摘 | Christophi GP Isackson PJ Blaber S | 2004 | J Neurochem2004，91，6： | 1 |
| 12 | Prevention of dia- betes in women with a history of gestational diabetes:effects of met- formin and lifestyle interventions显示文摘 | Ratnert RE Christophi CA Metzqer BE | 2008 | J Clin Endoerinol Metab2008，93，12： | 1 |
| 13 | Perioperative fluid prescription, complications and outcomes in major elective open gastrointestinal surgery显示文摘 | Warrillow S J Weinberg L Parker F Calzavacca P Licari E Aly A Bagshaw S Christophi C Bellomo R | 2010 | Anaesthesia and Intensive Care2010，，2： | 1 |
| 14 | Autologousstem cells (adipose) and fibrin glue used to treat widespread traumatic calvarial defects: Case report 显示文摘 | Lendeckel S Jodicke A Christophis P | 2004 | J Craniomaxillofac Surg2004，32，： | 1 |
| 15 | Induction of IL-33 expression and activity in central nervous system glia显示文摘 | Hudson CA Christophi GP Gruber RC | 2008 | J Leukoc Biol2008，84，3： | 1 |
| 16 | Bimodal role of Kupffer cells during colorectal cancer liver metastasis显示文摘 | Wen SW Ager El Christophi C | 2013 | Cancer Biol Ther2013，14，7： | 1 |
| 17 | Induction of IL-33 expression and activity in central nervous system glia显示文摘 | Hudson CA Christophi GP Gruber RC | 2008 | J Leukoc Biol2008，84，3： | 1 |
| 18 | Preyention ofdiabetes in women with a history of gestatiunzd diabetes:effects of metformin and lifestyle interventions显示文摘 | Ratner RE Christophi CA Metzger BE et a1 | 2008 | J Clin Endocrinol Metab2008，93，： | 1 |
| 19 | Disturbances of the microcirculation in acute pancreatitis显示文摘 | Cuthbertson CM Christophi C | 2006 | Br J Suig2006，93，： | 1 |
| 20 | Diabetes Prevention Program Research Group Prevention of diabetes in women with a his- tory of gestational diabetes : Effects of mefformin and lifestyle inter- ventions 显示文摘 | Ratner RE Christophi CA Metzger BE | 2008 | J Clin Endocrinol Metab2008，93，12： | 1 |
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