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| 1 | Study on Thermal Simulation of Solidification in Heavy Section Ductile Iron显示文摘Using an artificial intelligent instrument and a computer feedback control method, a new thermal simulation systemis studied. Based on numerical simulation of casting solidification, a sample in the new system successfully simulatedthe solidification of heavy section ductile iron. The results show that the new thermal simulation system is accurateand reliable. Not only cooling curve but also graphite in the center of the thermal sample and the heavy sectionductile iron is identical. Realization of accurate thermal simulation of solidification in heavy section ductile iron willbe helpful for studying formation mechanism and controlling graphite degeneration in heavy section ductile iron. | Zhenhua LI Yanxiang LI Huiyuan GENG Jianjun CHEN Chunyan ZHOU Junfa CHEN | 2003 | Journal of Materials Science & Technology2003，19，z1： | 5 |
| 2 | SHRIMP zircon dating and LA-ICPMS Hf analysis of early Precambrian rocks from drill holes into the basement beneath the Central Hebei Basin,North China Craton显示文摘The Central Hebei Basin(CHB) is one of the largest sedimentary basins in the North China Craton,extending in a northeast-southwest direction with an area of >350 km2.We carried out SHRIMP zircon dating,Hf-in-zircon isotopic analysis and a whole-rock geochemical study on igneous and metasedimentary rocks recovered from drill holes that penetrated into the basement of the CHB.Two samples of gneissic granodiorite(XG1-1) and gneissic quartz diorite(J48-1) have magmatic ages of 2500 and2496 Ma.respectively.Their zircons also record metamorphic ages of 2.41-2.51 and 2.5 Ga,respectively.Compared with the gneissic granodiorite,the gneissic quartz diorite has higher ∑REE contents and lower Eu/Eu* and(La/Yb)n values.Two metasedimentary samples(MG1,H5) mainly contain 2.5 Ga detrital zircons as well as late Paleoproterozoic metamorphic grains.The zircons of different origins haveεHf(2.5 Ga) values and Hf crustal model ages ranging from 0 to 5 and 2.7 to 2.9 Ga.respectively.Therefore,2.5 Ga magmatic and Paleoproterozoic metasedimentary rocks and late Neoarchean to early Paleoproterozoic and late Paleoproterozoic tectono-thermal events have been identified in the basement beneath the CHB.Based on regional comparisons,we conclude that the early Precambrian basement beneath the CHB is part of the North China Craton. | Yusheng Wan Xianzheng Zhao Zejiu Wang Dunyi Liu Alfred Krner Chunyan Dong Hangqian Xie Yuansheng Geng Yuhai Zhang Runlong Fan Huiyi Sun | 2014 | Geoscience Frontiers2014，5，4： | 3 |
| 3 | Effects of dynamic ultra-high pressure homogenization on the structure and functional properties of casein显示文摘Dynamic ultra-high pressure homogenization(UHPH)is a novel high-pressure processing technique.In this study,the effects of dynamic UHPH on the structure and functional properties of casein were systematically investigated.It was found that the functional properties of casein changed with dynamic UHPH treatment,and the treatment at 150 MPa could significantly improve casein aqueous solubility,foaming and emulsifying properties.These functional improvements could be attributed to its structural changes,since the dynamic UHPH treatment could change the secondary structure,promote the interchange reaction between the disulfide bond and the sulfhydryl group,and increase the surface hydrophobicity.The obtained results could broaden the application of casein and provide ideas for the non-thermal processing of proteins. | Chunyan Wang Yaping Ma Benguo Liu Zhuangli Kang Sheng Geng Jianan Wang Lipeng Wei Hanjun Ma | 2019 | International Journal of Agricultural and Biological Engineering2019，12，1： | 1 |
| 4 | Evaluating extended land consumption in building life cycle to improve land conservation: A case study in Shenyang, China显示文摘 | Tang Xu LI Chunyan HU Shiyuan LIU Yaolin GENG Hong | 2016 | Resources, Conservation & Recycling2016，，： | 1 |
| 5 | Regulatory Role of Retinoic Acid in Male Pregnancy of the Seahorse显示文摘Seahorses epitomize the exuberance of evolution.They have the unique characteristic of male pregnancy,which includes the carrying of many embryos in a brood pouch that incubates and nourishes the embryos,similar to the mammalian placenta.However,the regulatory networks underlying brood pouch formation and pregnancy remain largely unknown.In this study,comparative transcriptomic and metabolomic profiling on the lined seahorse Hippocampus erectus,with unformed,newly formed,and pregnant brood pouches identified a total of 141 and 2,533 differentially expressed genes together with 73 and 121 significantly differential metabolites related to brood pouch formation and pregnancy,respectively.Specifically,integrative omics analysis revealed that retinoic acid(RA)synthesis and signaling pathway played essential roles in the formation of the brood pouch and pregnancy.RA might function upstream of testosterone and progesterone,thereby directly influencing brood pouch formation by regulating the expression of fshr and cyp7a1.Our results also revealed that RA regulates antioxidant defenses,particularly during male pregnancy.Alternatively,pregnancy caused a consistent decrease in RA,canthaxanthin,astaxanthin,and glutathione synthetase,and an increase in susceptibility to oxidative stress,which may balance brood pouch development and reproduction in seahorses and pave the way to successful gestation. | Chunyan Li Yongxin Li Geng Qin Zelin Chen Meng Qu Bo Zhang Xue Han Xin Wang Pei-yuan Qian Qiang Lin | 2020 | The Innovation2020，1，3： | 0 |
| 6 | Removal of multicomponent VOCs in off-gases from an oil refining wastewater treatment plant by a compost-based biofilter system显示文摘Waste gases from oil refining wastewater treatment plants are often characterized by the presence of multicomponent and various concentrations of compounds.An evaluation of the performance and feasibility of removing multicomponent volatile organic compounds(VOCs)in off-gases from oil refining wastewater treatment plants was conducted in a pilot-scale compost-based biofilter system.This system consists of two identical biofilters packed with compost and polyethylene(PE).This paper investigates the effects of various concentrations of nonmethane hydrocarbon(NMHC)and empty bed residence time(EBRT)on the removal efficiency of NMHC.Based on the experimental results and practical applications,an EBRT of 66 s was applied to the biofilter system.The removal efficiencies of NMHC were within the range of 47%–100%.At an EBRT of 66 s,the average removal efficiency of benzene,toluene,and xylene were more than 99%,99%,and 100%,respectively.The results demonstrated that multicomponent VOCs in off-gases from the oil refining wastewater treatment plant could be successfully removed in the biofilter system,which may provide useful information concerning the design criteria and operation of full-scale biofilters. | Dan WU Chunyan ZHANG Changjun GENG Li HAO Xie QUAN | 2009 | Frontiers of Environmental Science & Engineering2009，3，4： | 0 |
| 7 | Spintronic terahertz emission with manipulated polarization (STEMP)显示文摘Highly efficient generation and arbitrary manipulation of spin-polarized terahertz(THz)radiation will enable chiral lightwave driven quantum nonequilibrium state regulation,induce new electronic structures,consequently provide a powerful experi-mental tool for investigation of nonlinear THz optics and extreme THz science and applications.THz circular dichromic spectroscopy,ultrafast electron bunch manipulation,as well as THz imaging,sensing,and telecommunication,also need chiral THz waves.Here we review optical generation of circularly-polarized THz radiation but focus on recently emerged polarization tunable spintronic THz emission techniques,which possess many advantages of ultra-broadband,high efficiency,low cost,easy for integration and so on.We believe that chiral THz sources based on the combination of electron spin,ultra-fast optical techniques and material structure engineering will accelerate the development of THz science and applications. | Peiyan Li Shaojie Liu Xinhou Chen Chunyan Geng Xiaojun Wu | 2022 | Frontiers of Optoelectronics2022，15，1： | 0 |
| 8 | Wnt8a is one of the candidate genes that play essential roles in the elongation of the seahorse prehensile tail显示文摘Seahorses are a hallmark of specialized morphological features due to their elongated prehensile tail.However,the underlying genomic grounds of seahorse tail development remain elusive.Herein,we evaluated the roles of essential genes from the Wnt gene family for the tail developmental process in the lined seahorse(Hippocampus erectus).Comparative genomic analysis revealed that the Wnt gene family is conserved in seahorses.The expression profiles and in situ hybridization suggested that Wnt5a,Wnt8a,and Wnt11 may participate in seahorse tail development.Like in other teleosts,Wnt5a and Wntll were found to regulate the development of the tail axial mesoderm and tail somitic mesoderm,respectively.However,a significantly extended expression period of Wnt8a during seahorse tail development was observed.Signaling pathway analysis further showed that Wnt5a up-regulated the expression of the tail axial mesoderm gene(Shh),while interaction analysis indicated that Wnt8a could promote the expression of Wntll.In summary,our results indicate that the special extended expression period of Wnt8a might promote caudal tail axis formation,which contributes to the formation of the elongated tail of the seahorse. | Bo Zhang Geng Qin Lili Qu Yanhong Zhang Chunyan Li Chunlei Cang Qiang Lin | 2021 | Marine Life Science & Technology2021，3，4： | 0 |
| 9 | The enhancing effect and promoting mechanisms of the stereoisomeric monoterpene alcohol esters as enhancers for drugs with different physicochemical properties显示文摘To explore the structure-activity connections of amphiphilic permeation enhancers containing the length of the hydrophobic chains as well as the properties of the polar head,O-acylgeraniol and O-acylnerol derivatives were synthesized from geraniol/nerol(cis-isomer of geraniol) and pharmaceutical excipient acids in this research. Their promotion of the percutaneous absorption of three drugs as the model, flurbiprofen(FP), isosorbide dinitrate(ISDN) and donepezil(DNP), which were selected based on their physicochemical properties,was tested by in vitro skin penetration and in vivo. Molecular simulation, ATR-FTIR, CLSM and histological observation were implement to evaluate the mode of action of the enhancers.The results indicated that(E)-3,7-dimethyl-2,6-octadien-1-yl tetradecanoate(GER-C14, trans-)achieved the highest enhancement ability for the three drugs;additionally, the in vivo results obtained were in good correlation with the in vitro data. Molecular docking results suggested that enhancers loosen the hydrogen bonds between ceramides, and the results of molecular simulation indicated that GER-C14, NER-C14 could insert into the middle of the lipid bilayer to form an independent phase. According to ATR-FTIR and histological evaluation, the enhancers extracted lipids and influenced the protein region, thereby disturbing the skin array. In addition, CLSM described the dynamic effects of enhancers on lipids between stratum corneum(SC) cells. In conclusion, GER-C14 had a better penetration promotion effect, which broadened our understanding of stereoisomeric penetration enhancers. | Heping Wang Yan Li Chunyan Wang Jing Wang Bo Ren Xiaona Li Mingzhu Li Dandan Geng Chensi Wu Ligang Zhao | 2022 | Asian Journal of Pharmaceutical Sciences2022，17，1： | 0 |
| 10 | GenOrigin: A comprehensive protein-coding gene origination database on the evolutionary timescale of life显示文摘The origination of new genes contributes to the biological diversity of life. New genes may quickly build their network, exert important functions, and generate novel phenotypes. Dating gene age and inferring the origination mechanisms of new genes, like primate-specific genes, is the basis for the functional study of the genes. However, no comprehensive resource of gene age estimates across species is available. Here,we systematically date the age of 9,102,113 protein-coding genes from 565 species in the Ensembl and Ensembl Genomes databases, including 82 bacteria, 57 protists, 134 fungi, 58 plants, 56 metazoa, and 178 vertebrates, using a protein-family-based pipeline with Wagner parsimony algorithm. We also collect gene age estimate data from other studies and uniformly distribute the gene age estimates to time ranges in a million years for comparison across studies. All the data are cataloged into Gen Origin(http://genorigin.chenzxlab.cn/), a user-friendly new database of gene age estimates, where users can browse gene age estimates by species, age, and gene ontology. In Gen Origin, the information such as gene age estimates,annotation, gene ontology, ortholog, and paralog, as well as detailed gene presence/absence views for gene age inference based on the species tree with evolutionary timescale, is provided to researchers for exploring gene functions. | Yi-Bo Tong Meng-Wei Shi Sheng Hu Qian Yu-Jie Chen Zhi-Hui Luo Yi-Xuan Tu Yu-Li Xiong Ying-Jie Geng Chunyan Chen Zhen-Xia Chen | 2021 | Journal of Genetics and Genomics2021，48，12： | 0 |
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