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| 1 | 补体B因子是代谢综合征模型代谢与心血管特征的一个决定因素显示文摘补体B因子(complenment factor B,CFB)在2型糖尿病及心血管病患者脂肪组织及血清中水平升高,但与疾病发病机制的因果关系不明确。自发性高血压大鼠(spontaneously hypertensive rats,SHR)脂肪组织及血清中CFB也升高。为明确CFB在代谢综合征中的作用,研究者在SHR中敲除Cfb基因。 | 赵狄 练桂丽 Coan PM Barrier M Alfazema N Carter RN Marion de Procé S Dopico XC Garcia Diaz A Thomson A Jackson-Jones LH Moyon B Webster Z Ross D Moss J Arends MJ Morton NM Aitman TJ | 2017 | 中华高血压杂志2017，25，8： | 3 |
| 2 | Indications for selective intraoperative cholangiography显示文摘 | Livingston EH Miller JA Coan B | 2005 | J Gastrointest Surg2005，9，9： | 1 |
| 3 | Prediction of the strength of the elderly proximal femur bybone mineral density and quan-titative ultrasound measurements of the heel and tibia显示文摘 | Bouxsein M L Coan B S Lee S C | 1999 | Bone1999，25，1： | 1 |
| 4 | Using Distrib- uted Topology Update and Preplanned Configuration to Achieve Trunk Network Survivability 显示文摘 | COAN B A LELAND W E VECECHI M P | 1991 | IEEE Trans Relialibity1991，40，4： | 1 |
| 5 | 3T MRI quantification of hipp- ocampal volume and Signal in mesial temporal lobe epilepsy improves detection of hippocampal sclerosis显示文摘 | Coan AC Kubota B Bergo FPG ctal | 2014 | AJNR Am J Neuroradiol2014，35，1： | 1 |
| 6 | Prime:Byzantine Replication Under Attack显示文摘 | Amir Y Coan B Kirsch J | 2011 | IEEE Transactions on Dependable and Secure Computing2011，8，4： | 1 |
| 7 | Voluntary facial expression and hemispheric asymmetry over the frontal cortex 显示文摘 | Coan J A Allen J J B HarmomJones E | 2001 | Psychophysiology2001，38，91： | 1 |
| 8 | Using distributed topology update and preplanned configurations to achieve trunk network survivability显示文摘 | B A Coan | 1991 | IEEE Transactions on Reliability1991，40，4： | 1 |
| 9 | Costs and utilization of intraoperative cholangiography 显示文摘 | Livingston EH Miller JA Coan B | 2007 | J Gastrointest Surg2007，11，9： | 1 |
| 10 | Costs and utilization of intraperative cholangiography显示文摘 | Miller JA Coan B | 2007 | J Gastrointset Surg2007，11，9： | 1 |
| 11 | How to establish an endoscopic bariatric practice显示文摘Obesity is a chronic,progressive,and relapsing disease of excess adiposity that contributes to more than two hundred medical conditions and is projected to affect more than half the adult population of the United States by the year 2030.Given the limited penetrance of traditional bariatric surgery,as well as the cost and adherence barriers to anti-obesity medications,there is growing interest in the rapidly evolving field of endoscopic bariatric therapies(EBTs).EBTs are minimally invasive,same-day,per-oral endoscopic procedures and include endoscopic sleeve gastroplasty,intragastric balloons,and endoscopic bariatric revisional procedures.This field represents an exciting and innovative subspe-cialty within gastroenterology.However,building a successful endoscopic bariatric practice requires intentional,coordinated,and sustained efforts to overcome the numerous obstacles to entry.Common barriers include acquisition of the technical and cognitive skillset,practice limitations including the availability of nutrition counseling,facility capabilities,direct-to-consumer marketing,and financial pressures such as facility and anesthesia fees.As the highest-volume center for metabolic and bariatric endoscopy in the United States,we provide insights into successfully establishing an endoscopic bariatric program. | Daniel B Maselli Lauren L Donnangelo Brian Coan Christopher E McGowan | 2024 | World Journal of Gastrointestinal Endoscopy2024，16，4： | 0 |
| 12 | Transoral outlet reduction:Outcomes of endoscopic Roux-en-Y gastric bypass revision in 284 patients at a community practice显示文摘BACKGROUND Transoral outlet reduction(TORe)is a minimally invasive endoscopic revision of Roux-en-Y gastric bypass(RYGB)for weight recurrence;however,little has been published on its clinical implementation in the community setting.AIM To characterize the safety and efficacy of TORe in the community setting for adults with weight recurrence after RYGB.METHODS This is a retrospective cohort study of argon plasma coagulation and purse-string suturing for gastric outlet reduction in consecutive adults with weight recurrence after RYGB at a single community center from September 2020 to September 2022.Patients were provided longitudinal nutritional support via virtual visits.The primary outcome was total body weight loss(TBWL)at twelve months from TORe.Secondary outcomes included TBWL at three months and six months;excess weight loss(EWL)at three,six,and twelve months;twelve-month TBWL by obesity class;predictors of twelve-month TBWL;rates of post-TORe stenosis;and serious adverse events(SAE).Outcomes were reported with descriptive statistics.RESULTS Two hundred eighty-four adults(91.9%female,age 51.3 years,body mass index 39.3 kg/m^(2))underwent TORe an average of 13.3 years after RYGB.Median pre-and post-TORe outlet diameter was 35 mm and 8 mm,respectively.TBWL was 11.7%±4.6%at three months,14.3%±6.3%at six months,and 17.3%±7.9%at twelve months.EWL was 38.4%±28.2%at three months,46.5%±35.4%at six months,and 53.5%±39.2%at twelve months.The number of follow-up visits attended was the strongest predictor of TBWL at twelve months(R^(2)=0.0139,P=0.0005).Outlet stenosis occurred in 11 patients(3.9%)and was successfully managed with endoscopic dilation.There was one instance of post-procedural nausea requiring overnight observation(SAE rate 0.4%).CONCLUSION When performed by an experienced endoscopist and combined with longitudinal nutritional support,purse-string TORe is safe and effective in the community setting for adults with weight recurrence after RYGB. | Daniel B Maselli Vibhu Chittajallu Chase Wooley Areebah Waseem Daniel Lee Michelle Secic Lauren LDonnangelo Brian Coan Christopher E McGowan | 2023 | World Journal of Gastrointestinal Endoscopy2023，15，10： | 0 |
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