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5篇 您的检索式:作者名="Colette Smith"
    题名 作者 年代 出处 被引量
1Systemic Amyloidosis in E ngland: an epidemiological study显示文摘Jennifer H. Pinney Colette J. Smith Jessi B. Taube Helen J. Lachmann Christopher P. Venner Simon D. J. Gibbs Jason Dungu Sanjay M. Banyperasad Ashutosh D. Wechalekar Carol J. Whelan Philip N. Hawkins Julian D. Gillmore 2013Br J Haematol2013,,4:1
2Trends in underlying causes of death in people with HIV from 1999 to 2011 (D:A:D): a multicohort collaboration显示文摘Colette J Smith Lene Ryom Rainer Weber Philippe Morlat Christian Pradier Peter Reiss Justyna D Kowalska Stephane de Wit Matthew Law Wafaa el Sadr Ole Kirk Nina Friis-Moller Antonella d’Arminio Monforte Andrew N Phillips Caroline A Sabin Jens D Lundgren 20142014 (9939)2014,,9939:1
3The role of antiretroviral therapy in the incidence of pancreatitis in HIV-positive individuals in the EuroSIDA study显示文摘Colette J Smith Christian H Olsen Amanda Mocroft Jean Paul Viard Schlomo Staszewski George Panos Therese Staub Anders Blaxhult Norbert Vetter Jens D Lundgren 2008AIDS2008,,1:1
4Cytomegalovirus glycoprotein-B vaccine with MF59 adjuvant in transplant recipients: a phase 2 randomised placebo-controlled trial显示文摘Paul D Griffiths Anna Stanton Erin McCarrell Colette Smith Mohamed Osman Mark Harber Andrew Davenport Gareth Jones David C Wheeler James O’Beirne Douglas Thorburn David Patch Claire E Atkinson Sylvie Pichon Paul Sweny Marisa Lanzman Elizabeth Woodford Emi 2011The Lancet2011,,9773:1
5Prevalence of significant liver disease in human immunodeficiency virus-infected patients exposed to Didanosine: A cross sectional study显示文摘AIM To identify significant liver disease [including nodular regenerative hyperplasia(NRH)] in asymptomatic Didanosine(DDI) exposed human immunodeficiency virus(HIV) positive patients.METHODS Patients without known liver disease and with > 6 mo previous DDI use had liver stiffness assessed by transient elastography(TE). Those with alanine transaminase(ALT) above upper limit normal and/or TE > 7.65 k Pa underwent ultrasound scan(U/S). Patients with:(1) abnormal U/S; or(2) elevated ALT plus TE > 7.65 k Pa;or(3) TE > 9.4 k Pa were offered trans-jugular liver biopsy(TJLB) with hepatic venous pressure gradient(HVPG) assessment.RESULTS Ninety-nine patients were recruited, median age 50 years(range 31-70), 81% male and 70% men who have sex with men. Ninety-five percent with VL < 50 copies on antiretroviral therapy with median CD4 count 639 IU/L. Median DDI exposure was 3.4 years(range 0.5-14.6). Eighty-one had a valid TE readings(interquartile range/score ratio < 0.3): 71(88%) < 7.65 k Pa, 6(7%) 7.65-9.4 k Pa and 4(6%) > 9.4 k Pa. Seventeen(17%) met criteria for TJLB, of whom 12 accepted. All had HVPG < 6 mm Hg. Commonest histological findings were steatosis(n = 6), normal architecture(n = 4) and NRH(n = 2), giving a prevalence of previously undiagnosed NRH of 2%(95%CI: 0.55%, 7.0%).CONCLUSION A screening strategy based on TE, liver enzymes and U/S scan found a low prevalence of previously undiagnosed NRH in DDI exposed, asymptomatic HIV positive patients. Patients were more likely to have steatosis highlighting the increased risk of multifactorial liver disease in this population.Sarah Logan Alison Rodger Laura Maynard-Smith James O'Beirne Thomas Fernandez Filippo Ferro Colette Smith Sanjay Bhagani 2016World Journal of Hepatology2016,8,36:0
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