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| 1 | Intraneuronal beta-amyloid aggregates, neurodegenerafion, and neuron loss in la'ansgenic mice with five familial Alzheimer's disease mutations :potential factors in amyloid plaque formation 显示文摘 | Holly Oakley Sarah L Cole Sreemathi Logan | 2006 | J Neurosci2006，26，10： | 1 |
| 2 | Acute variceal haemorrhage in the United Kingdom: Patient characteristics, management and outcomes in a nationwide audit显示文摘 | Vipul Jairath Sunita Rehal Richard Logan Brennan Kahan Sarah Hearnshaw Simon Stanworth Simon Travis Michael Murphy Kelvin Palmer Andrew Burroughs | 2013 | Digestive and Liver Disease2013，，： | 1 |
| 3 | Beneficial Effect of Mechanical Stimulation on the Regenerative Potential of Muscle-Derived Stem Cells Is Lost by Inhibiting Vascular Endothelial Growth Factor显示文摘 | Sarah A. Beckman William C.W. Chen Ying Tang Jonathan D. Proto Logan Mlakar Bing Wang Johnny Huard | 2013 | Arteriosclerosis, Thrombosis, and Vascular Biology2013，，8： | 1 |
| 4 | Prevalence, management, and outcomes of patients with coagulopathy after acute nonvariceal upper gastrointestinal bleeding in the United Kingdom显示文摘 | Vipul Jairath Brennan C. Kahan Simon J. Stanworth Richard F.A. Logan Sarah A. Hearnshaw Simon P.L. Travis Kelvin R. Palmer Michael F. Murphy | 2012 | Transfusion2012，，5： | 1 |
| 5 | Escherichia coli O157:H7 sepsis following fecal microbiota transplant in an IgA-deficient inflammatory bowel disease patient显示文摘Introduction Clostridioides difficile infection(CDI)is a common gastrointestinal illness worldwide,with increased prevalence and worse outcomes in patients with inflammatory bowel disease(IBD)[1].Fecal microbiota transplant(FMT)is an effective treatment for recurrent CDIs(RCDIs)with minimal serious adverse events(SAEs)reported[2].While immunosuppressive medications increase susceptibility to infections,studies have shown that FMT does not increase SAE risk in immunocompromised patients(including IBD patients on immunosuppressive therapy)[3]. | Landen S.Burstiner Jared Silver Logan J.Burstiner Arian Teymoorian Kumar Pallav Demarre Jones Anna Owings Sarah Glover | 2022 | Gastroenterology Report2022，10，1： | 0 |
| 6 | Apocrine adenocarcinoma of the eyelid显示文摘Dear Sir,Sweat gland neoplasms of the ocular region are rare[1].Traditionally,these lesions are classified as either of eccrine or apocrine origin.The cardinal feature of apocrine tumors includes having apical decapitation secretions from the cells rather than forming simple secretory units with tubules,such as the case with their eccrine counterpart[2-4].Apocrine lesions can be both benign and malignant.There | Sultan S Aldrees Pablo Zoroquiain Sarah A Alghamdi Patrick Logan Conrad Kavalec Miguel Burnier | 2016 | International Journal of Ophthalmology(English edition)2016，9，7： | 0 |
| 7 | The Fold-Illuminator:A low-cost,portable,and disposable incubator-illuminator device显示文摘Fluorescent reporters have revolutionized modern applications in the fields of molecular and synthetic biology,enabling applications ranging from education to point-of-care diagnostics.Past advancements in these fields have primarily focused on improving reaction conditions,the development of new applications,and the broad dissemination of these technologies.However,field and classroom-based applications have remained limited in part due to the nature of fluorescent signal detection,which often requires the use of costly lab equipment to observe and quantify fluorescence readouts.Users without access to laboratory equipment rely on qualitative assessments of fluorescence,a process that remains highly variable from user-to-user even within the same classroom.To overcome this challenge,we have developed a foldable illuminator and incubator device to support field-applications of synthetic biology-based biosensors for education and diagnostics.The Fold-Illuminator is an affordable,portable,and recyclable device that allows for the visible detection of fluorescent biomolecules.The Fold-Illuminator’s design allows for assembly in under 10 min,a user can then utilize the optional heating element to incubate biochemical reactions and visualize fluorescence outputs in a defined and light-controlled environment.Interchangeable LED strips and light-filtering screens provide modularity to pair with the fluorescence wavelengths of interest.The user can then unfold the device for convenient storage,transport,or even recycling.The cost for the Fold-Illuminator is$5.58 USD and is compatible with an optional heating element for an additional$3.98 cost,with potential for further reductions in cost for larger quantities.Open-source templates for cutting device parts from paper stock are provided for both printing and cutting by hand;cutting can also be achieved with consumer-grade smart cutting machines such as the Cricut®.Combined with the broad applications of fluorescent reporters,the Fold-Illuminator has the potential to improve access to fluorescence visualization and quantification for new users as well as emerging field applications. | Logan R.Burrington Emran Baryal Katherine Hui Emmett Lambert Sarah T.Harding Javin P.Oza | 2021 | Synthetic and Systems Biotechnology2021，6，2： | 0 |
| 8 | Prevalence of significant liver disease in human immunodeficiency virus-infected patients exposed to Didanosine: A cross sectional study显示文摘AIM To identify significant liver disease [including nodular regenerative hyperplasia(NRH)] in asymptomatic Didanosine(DDI) exposed human immunodeficiency virus(HIV) positive patients.METHODS Patients without known liver disease and with > 6 mo previous DDI use had liver stiffness assessed by transient elastography(TE). Those with alanine transaminase(ALT) above upper limit normal and/or TE > 7.65 k Pa underwent ultrasound scan(U/S). Patients with:(1) abnormal U/S; or(2) elevated ALT plus TE > 7.65 k Pa;or(3) TE > 9.4 k Pa were offered trans-jugular liver biopsy(TJLB) with hepatic venous pressure gradient(HVPG) assessment.RESULTS Ninety-nine patients were recruited, median age 50 years(range 31-70), 81% male and 70% men who have sex with men. Ninety-five percent with VL < 50 copies on antiretroviral therapy with median CD4 count 639 IU/L. Median DDI exposure was 3.4 years(range 0.5-14.6). Eighty-one had a valid TE readings(interquartile range/score ratio < 0.3): 71(88%) < 7.65 k Pa, 6(7%) 7.65-9.4 k Pa and 4(6%) > 9.4 k Pa. Seventeen(17%) met criteria for TJLB, of whom 12 accepted. All had HVPG < 6 mm Hg. Commonest histological findings were steatosis(n = 6), normal architecture(n = 4) and NRH(n = 2), giving a prevalence of previously undiagnosed NRH of 2%(95%CI: 0.55%, 7.0%).CONCLUSION A screening strategy based on TE, liver enzymes and U/S scan found a low prevalence of previously undiagnosed NRH in DDI exposed, asymptomatic HIV positive patients. Patients were more likely to have steatosis highlighting the increased risk of multifactorial liver disease in this population. | Sarah Logan Alison Rodger Laura Maynard-Smith James O'Beirne Thomas Fernandez Filippo Ferro Colette Smith Sanjay Bhagani | 2016 | World Journal of Hepatology2016，8，36： | 0 |
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