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| 1 | Budesonide induces complete remission in autoimmune hepatitis显示文摘瞄准:泼尼松和 azathioprine 为自体免疫的肝炎(AIH ) 代表标准疗法。然而,仅仅, 65% 病人进入完全的组织学的宽恕。最近, budesonide (芽) 被报导是一种有希望的选择。在这研究,我们在 AIH 估计了芽的功效和安全。方法:十八个病人(12 个女人, 6 个男人;吝啬的年龄 45.4+/-21 年) 与芽(Budenofalk ) 与 AIH 被对待在上面三次每日、跟随的 3 mg 为至少 24 wk.Seven,病人们也有主要胆汁性肝硬变(n=5 ) 或主要致硬化的胆管炎(n=2 ) 的特征。先进的肝纤维变性或肝硬化在 6 个病人是在场的。结果:十五(83%) 病人们有完全的临床、生物化学的宽恕。十个病人,与尖锐肝炎包括五,作为首要的治疗被给芽,哪个七进入宽恕。三个病人,二与肝肝硬化,没改善。有第二线的治疗的所有病人经历了长期的宽恕。组织学的宽恕也在三个病人被看见。临床上相关的导致芽的副作用与肝肝硬化(n=4 ) 仅仅在病人被记录。结论:芽在在我们有 AIH.Side 效果的病人的多数的宽恕正式就职是有效的,治疗失败主要与肝肝硬化在病人被观察。 | Antal Csepregi Christoph R(o|¨)cken Gerhard Treiber Peter Malfertheiner | 2006 | World Journal of Gastroenterology2006，12，9： | 14 |
| 2 | Antioxidant potential,tannin and polyphenol contents of seed and pericarp of three Coffea species显示文摘Objective:To investigate the antioxidant activity,total phenolic and total tannin content of the pericarp and the seed of Coffea benghalensis(C.benghalensis) and Coffea liberica compared to Coffea arabica(C.arabica).Methods:The antioxidant potential,total tannin and polyphenol contents of the immature and mature seed and pericarp of C.benghalensis and Coffea liberica were quantified and compared to C.arabica.Enhanced chemiluminescence(ECL).2,2-diphenyl-1-picrylhydruzyl(DPPH).oxygen radical absorbance capacity,Folin-Ciocaltcau method and total tannin content assays were used.Results:Trolox equivalent(TE/g plant material) values obtained by ECL and DPPH methods showed loose correlation(r^2=0.587)while those measured by oxygen radical absorbance capacity assay were higher without correlation in each plant.A closer correlation was detected between the ECL method and the percentage antioxidant activity of the DPPH technique(r^2=0.610 7) in each species,however the immature pericarp of C.benghalensis showed much higher DPPH scavenging potential than was seen in the ECL assay.The immature pericarp of C.benghalensis expressed the highest tannin and polyphenol content,and a high polyphenol level was also detected in the immature seed of C.arabica.The immature pericarp of Bengal and Liberian coffees showed the largest amount of phenolic contents.Conclusions:The obtained data highlight the potential role of C.benghalensis as a new source of natural antioxidants and polyphenols compared to C.arabica. | va Brigitta Patay Nikolett Sali Tams Kszegi Rita Csepregi Viktória Lilla Blaz Tibor Sebastian Németh Tibor Németh Nóra Papp | 2016 | Asian Pacific Journal of Tropical Medicine2016，9，4： | 3 |
| 3 | Acute exacerbation of autoimmune hepatitis induced by Twinrix显示文摘We report on a 26-year-old man who presented with severe jaundice and elevated serum liver enzyme activities after having received a dose of Twinrix(○R). In his past medical history, jaundice or abnormal liver function tests were never recorded. Following admission, an elevated immunoglobulin G level and antinuclear antibodies at a titer of 320 with a homogenous pattern were found. Histology of a liver biopsy showed marked bridging liver fibrosis and a chronic inflammation, compatible with autoimmune hepatitis. Treatment was started with budesonide and ursodeoxycholic acid,and led to complete normalization of the pathological liver function tests. We believe that Twinrix(○R) led to an acute exacerbation of an unrecognized autoimmune hepatitis in our patient. The pathogenesis remains to be clarified. It is tempting to speculate that inactivated hepatitis A virus and/or recombinant surface antigen of the hepatitis B virus -as seen in patients with chronic hepatitis C and unrecognized autoimmune hepatitis who were treated with interferon alpha-might have been responsible for disease exacerbation. | Antal Csepregi Gerhard Treiber Christoph R(o|¨)cken Peter Malfertheiner | 2005 | World Journal of Gastroenterology2005，11，26： | 2 |
| 4 | Use of alfentanil with propofol for nasotracheal intubation without neuromuscular block 显示文摘 | Coghlan SFE McDonald PF Csepregi G | 1993 | Br J Anaesth1993，70，1： | 1 |
| 5 | Budesonide induces complete iemission in autoimmune hepatitis 显示文摘 | Csepregi A Rocken C Treiber G | 2006 | world J Gastroenterol2006，12，： | 1 |
| 6 | Effects of interferon treatment on the glucose metabolism of patients with chronic hepatitis C显示文摘 | Nemesanszky E Pusztay M Csepregi A | 2000 | Eur J Intern Med2000，11，3： | 1 |
| 7 | Do autoantibodies predict autoimmune liver disease in primary Sjogren's syndrome? Data of 180 patients upon a 5 year follow-up显示文摘 | Csepregi A Szodoray P Zeher M | 2002 | Scand J Immunol2002，56，： | 1 |
| 8 | AnisotropicEtching of Crystalline Silicon in Alkaline Solutions显示文摘 | Seidel H Csepregi L Heuberger A | 1990 | JElectrochem Soc1990，137，11： | 1 |
| 9 | Effects of interferon treatment on the glucose metabolism of Patients with chronic hePatitisC显示文摘 | Nemeasnszky E Pusztay M CsePregi A | 2000 | Eur J Intern Med2000，11，3： | 1 |
| 10 | Effects of interfer on treatment on the glucose metabolism of patients with chronic hepatitis C显示文摘 | Nemesanszky E Pusztay M Csepregi A | 2000 | Eur J Intern Med2000，11，： | 1 |
| 11 | Effects of interferon treatment on the glucose metabolism of patients with chronic hepatitis C 显示文摘 | Nemesanszky E Pusztay M Csepregi A | 2000 | Eur J Intern Med2000，11，3： | 1 |
| 12 | LKM3 autoantibodies in hepatitis C cirrhosis: a further phenomenon of the HCV-induced autoimmunity显示文摘 | Csepregi A Nemes6nszky E Luettig B | 2001 | Am J Gastroenterol2001，96，3： | 1 |
| 13 | Use of alfentanil with propofol for nasotracheal intubation without neuromuscular block显示文摘 | Coghlan SF McDonald PF Csepregi G | 1993 | Br J Anacsth1993，70，1： | 1 |
| 14 | Three-dimensional structuring of silicon for sensor application显示文摘 | Seidel H Csepregi L | 1983 | Sensors and Actuators1983，4，3： | 1 |
| 15 | Use of alfentanil with propofol for nasotracheal intubation without neuromuscular block显示文摘 | Coghlan SF McDonald PF Csepregi G | 1993 | Anaesthesia1993，70，： | 1 |
| 16 | Effects of interferon treatment on the glucose metabolism of patients with chronic hepatitis C显示文摘 | Elemér Nemesánszky Margit Pusztay Antal Csepregi | 2000 | European Journal of Internal Medicine2000，，3： | 1 |
| 17 | Effects of interferon treatment on the glucose metabolism of patients with chronic hepatitis C显示文摘 | Nemesanszky E Pusztay M Csepregi A | 2000 | Eur J Intern Med2000，11，3： | 1 |
| 18 | Anisotropic etching of crystalline silicon in alkaline solutions I:orientation dependence and behavior of passivation layers显示文摘 | SEIDEL H CSEPREGI L HEUBERGER A | 1990 | Journal of the Electrochemical Society1990，137，11： | 1 |
| 19 | Effects of interferon treatment on the glucose metabolism of patients with chronic hepatitisc显示文摘 | Nemesanszky E Pusztay M Csepregi A | 2000 | Eur J Intern Med2000，11，3： | 1 |
| 20 | Do qutoantibodies dredict autoimmune liver disease in primary Sjgren's syndrome Date of 180 patients upon a 5 year follow-up显示文摘 | CSEPREGI A SZODORAY P ZEHER M | 2002 | Scandinavian Journal of Immunology2002，56，6： | 1 |
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