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| 1 | The Relationship Between the Gut Microbiome and Neurodegen-erative Diseases显示文摘Many recent studies have shown that the gut microbiome plays important roles in human physiology and pathology.Also,microbiome-based therapies have been used to improve health status and treat diseases.In addition,aging and neurodegenerative diseases,including Alzheimer’s disease and Parkinson’s disease,have become topics of intense interest in biomedical research.Several researchers have explored the links between these topics to study the potential pathogenic or therapeutic effects of intestinal microbiota in disease.But the exact relationship between neurodegenerative diseases and gut microbiota remains unclear.As technology advances,new techniques for studying the microbiome will be developed and refined,and the relationship between diseases and gut microbiota will be revealed.This article summarizes the known interactions between the gut microbiome and neurodegenerative diseases,highlighting assay techniques for the gut microbiome,and we also discuss the potential therapeutic role of microbiome-based therapies in diseases. | Xueling Zhu Bo Li Pengcheng Lou Tingting Dai Yang Chen Aoxiang Zhuge Yin Yuan Lanjuan Li | 2021 | Neuroscience Bulletin2021,37,10: | 6 |
| 2 | Complete degradation of di-n-octyl phthalate by biochemical cooperation between Gordonia sp strain JDC-2 and Arthrobacter sp strain JDC-32 isolated from activated sludge 显示文摘 | WU Xueling LIANG Renxing DAI Qinyun | 2010 | Journal of Hazardous Materials2010,176,: | 1 |
| 3 | Biodegradation of an endocrine-disrupting chemical di- n -butyl phthalate by newly isolated Agrobacterium sp. and the biochemical pathway显示文摘 | Xueling Wu Yangyang Wang Renxing Liang Qinyun Dai Decai Jin Weiliang Chao | 2011 | Process Biochemistry2011,,5: | 1 |
| 4 | Protective Effects of Vitamin E against Oxidative Damage Induced by Aβ(1-40)Cu(Ⅱ)Complexes显示文摘贝它淀粉的肽(贝它)被认为为老年的匾的形成负责,它是 Alzheimer 的疾病(广告)的特点 .Oxidativestress ,每氧化由蛋白质氧化和类脂化合物表明了在另外的改变之中,广告 brain.A 的一个特征种证据的身体在 beta1-40forming 的支持被介绍了在建筑群产生的 CuZn 超级氧化物象dismutase一样绑定 site.Abeta1-40 Cu ( II )绑铜的 oligomeric 建筑群从经由 Cu2+reduction 的 O2 的毒害神经的氢过氧化物( H2O2 ),尽管精确反应机制是不清楚的。 beta1-40 或 Abeta1-40Cu ( II )的毒性当(+) -alpha-tocopherol ( 维生素 E )在数据从版本和 H2O2 的形成证实了的乳酸脱氢酶( LDH )导出的 100 muM.The 的集中作为免费激进的抗氧化剂被增加时,到有教养的主要外皮的神经原的建筑群部分被稀释结果从 MTT 试金。这些调查结果显示到 beta1-40 的那铜绑定能产生 H2O2 的更大的生产,它在质膜和随后的 neuronal 死亡的完整导致一个故障。与维生素 E 对待的组展出了许多更细微的损坏,建议维生素 E 起在保护 neuronal 房间免受机能障碍或死亡的伤害的一个关键作用。 | Xueling DAI~1 Yaxuan SUN~2 and Zhaofeng JIANG~2 ~1College of Life Science,Capital Normal University,Bejing 100037,China ~2College of Applied Sciences Humanities of Beijing Union University,Beijing 100083,China | 2007 | Acta Biochimica et Biophysica Sinica2007,39,2: | 1 |
| 5 | Community Characteristics and Species Diversity of Wetland Plants in the Yangguan Nature Reserve of Dunhuang显示文摘As a typical inland wetland, Yangguan nature reserve wetland in Dunhuang is one of the important stops of migratory route for birds, which is vulnerable and particular. Study on the community characteristics and species diversity of wetland has great signifi cance for biodiversity protection. Based on the fi eld investigation, the fl oristic composition, geographical elements and species diversity of wetland plants were studied in Yangguan reserve of Dunhuang. The results showed that 26 families, 56 genera and 74 species were recorded in the study area. The largest families were the Gramineae and Chenopodiaceae, accounting for 29.73% of the total. Herbs were the most abundant life-form, accounting for 77.03% of the total. The fl oral geographical elements of the plants were mainly composed of temperate zone distribution type. By using two way indicator species analysis(TWINSPAN), the vegetation in 36 sampling plots could be classifi ed into 8 communities. The species diversity indexes of communities were relatively low, but had large differences among each other. According to the importance value, the Margalef richness index(Rm) ranged from 0 to 4.200. Simpson diversity index(D) was between 0 and 0.512; Shannon diversity index(H) ranged from 0 to 1.400, and Pielou evenness index(J) was within the range of 0.538 to 1.000. The results indicated that the plant species were relatively rare and simple in general, the species diversity of communities was low, and the ecological environment was fragile in Yangguan nature reserve of Dunhuang. | DAI Xueling ZHAO Tingwei MA Shoushi LIU Xingwen YANG Jinwu MA Haitao HE Wenli YANG Jing DUAN Hongling XIE Jianping | 2016 | Journal of Landscape Research2016,8,2: | 1 |
| 6 | Altered white matter microarchitecture in Parkinson’s disease:a voxel-based meta-analysis of diffusion tensor imaging studies显示文摘This study aimed to define the most consistent white matter microarchitecture pattern in Parkinson’s disease(PD)reflected by fractional anisotropy(FA),addressing clinical profiles and methodology-related heterogeneity.Web-based publication databases were searched to conduct a meta-analysis of whole-brain diffusion tensor imaging studies comparing PD with healthy controls(HC)using the anisotropic effect size–signed differential mapping.A total of 808 patients with PD and 760 HC coming from 27 databases were finally included.Subgroup analyses were conducted considering heterogeneity with respect to medication status,disease stage,analysis methods,and the number of diffusion directions in acquisition.Compared with HC,patients with PD had decreased FA in the left middle cerebellar peduncle,corpus callosum(CC),left inferior fronto-occipital fasciculus,and right inferior longitudinal fasciculus.Most of the main results remained unchanged in subgroup metaanalyses of medicated patients,early stage patients,voxel-based analysis,and acquisition with˂30 diffusion directions.The subgroup meta-analysis of medication-free patients showed FA decrease in the right olfactory cortex.The cerebellum and CC,associated with typical motor impairment,showed the most consistent FA decreases in PD.Medication status,analysis approaches,and the number of diffusion directions have an important impact on the findings,needing careful evaluation in future meta-analyses. | Xueling Suo Du Lei Wenbin Li Lei Li Jing Dai Song Wang Nannan Li Lan Cheng Rong Peng Graham J Kemp Qiyong Gong | 2021 | Frontiers of Medicine2021,15,1: | 0 |
| 7 | Legislative Perfection of Governance Structure of Farmer Professional Cooperatives in China显示文摘The development of modern agriculture can not be separated from the development of farmer professional cooperatives,and the core of sustainable development of the cooperatives lies in the formation of relatively perfect governance structure.Chapter IV of Law on Farmer Professional Cooperatives of People's Republic of China stipulates the organization structure of cooperatives.However,because of historical reasons and limitation of legislative techniques,there is much omission in the institutional regulation of cooperative governance.Due to inadequate system supply of farmer professional cooperatives and deficiency in related rights and obligations,normative guidance can not be provided for the governance practice of farmer professional cooperatives in China,thereby leading to the inefficiency of cooperative management.Therefore,it is imminent to revise the law. | Xueling DAI | 2017 | Asian Agricultural Research2017,9,12: | 0 |