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| 1 | Improved survival of porcine acute liver failure by a bioartificial liver device implanted with induced human functional hepatocytes显示文摘 | Xiao-Lei Shi Yimeng Gao YupengYan HuchengMa Lulu Sun Pengyu Huang Xuan Ni Ludi Zhang Xin Zhao Haozhen Ren Dan Hu Yan Zhou Feng Tian Yuan Ji Xin Cheng Guoyu Pan Yi-Tao Ding LijianHui | 2016 | Cell Research2016，26，2： | 31 |
| 2 | Recent rapid shortening of crust across the Tianshan Mts. and relative motion of tectonic blocks in the north and south显示文摘Based on the multiple-epoch Global Positioning System observations during a period from 1992 to 1999, we document directly a rapid crustal shortening of -20 mm/a across the western Tianshan Mts. (76°E), in contrast to a 4 mm/a convergent rate across the eastern Tianshan Mts. (87°E) and the north-south convergence across the mountain belt descends laterally from west to east. The direction of current crustal movement inferred by GPS sites along the southern flank of the Tianshan Mts. is approximately perpendicular to the easterly-trending mountain belt, indicating that the Tarim Basin thrust almost rightly into the Tianshan Mts. The Tarim Basin accommodates nearly no or a minor, if any, crustal deformation and rotates clockwise, as a rigid body in a whole, at a rate of 0.64°/Ma around a Euler pole at 95.7° E, 40.3°N (Anxi, Gansu) with respect to the stable Siberia. The relative motion between the Kazakh platform and the Dzungarian Basin is quite apparent. The Dzungar should be regarded as an | WANG Qi DING Guoyu QIAO Xuejun WANG Xiaoqiang YOU Xinzhao | 2000 | Chinese Science Bulletin2000，45，21： | 14 |
| 3 | Effect of dilution holes on the performance of a triple swirler combustor显示文摘A triple swirler combustor is considered to be a promising solution for future high temperature rise combustors. The present paper aims to study dilution holes including primary dilution holes and secondary dilution holes on the performance of a triple swirler combustor. Experimental investigations are conducted at different inlet airflow velocities(40–70 m/s) and combustor overall fuel–air ratio with fixed inlet airflow temperature(473 K) and atmospheric pressure. The experimental results show that the ignition is very difficult with specific performance of high ignition fuel–air ratio when the primary dilution holes are located 0.6H(where H is the liner dome height)downstream the dome, while the other four cases have almost the same ignition performance. The position of primary dilution holes has an effect on lean blowout stability and has a large influence on combustion efficiency. The combustion efficiency is the highest when the primary dilution holes are placed 0.9H downstream the dome among the five different locations.For the secondary dilution holes, the pattern factor of Design A is better than that of Design B. | Ding Guoyu He Xiaomin Zhao Ziqiang An Bokun Song Yaoyu Zhu Yixiao | 2014 | Chinese Journal of Aeronautics2014，27，6： | 13 |
| 4 | Chemical and Isotopic Characteristics of the Water and Suspended Particulate Materials in the Yangtze River and Their Geological and Environmental Implications显示文摘The chemical and isotopic characteristics of the water and suspended particulate materials(SPM) in the Yangtze River were investigated on the samples collected from 25 hydrological monitoring stations in the mainsteam and 13 hydrological monitoring stations in the major tributaries during 2003 to 2007. The water samples show a large variation in both δD( 30‰ to 112‰) and δ18O( 3.8‰ to 15.4‰) values. Both δD and δ18O values show a decrease from the river head to the Jinsha Jiang section and then increase downstream to the river mouth. It is found that the oxygen and hydrogen isotopic compositions of the Yangtze water are controlled by meteoric precipitation, evaporation, ice(and snow) melting and dam building. The Yangtze SPM concentrations show a large variation and are well corresponded to the spatial and temporal changes of flow speed, runoff and SPM supply, which are affected by the slope of the river bed, local precipitation rate, weathering intensity, erosion condition and anthropogenic activity. The Yangtze SPM consists of clay minerals, clastic silicate and carbonate minerals, heavy minerals, iron hydroxide and organic compounds. From the upper to lower reaches, the clay and clastic silicate components in SPM increase gradually, but the carbonate components decrease gradually, which may reflect changes of climate and weathering intensity in the drainage area. Compared to those of the upper crust rocks, the Yangtze SPM has lower contents of SiO2, CaO, K2 O and Na2 O and higher contents of TFe2 O3 and trace metals of Co, Ni, Cu, Zn, Pb and Cd. The ΣREE in the Yangtze SPM is also slightly higher than that of the upper crust. From the upper to lower reaches, the CaO and MgO contents in SPM decrease gradually, but the SiO2 content increases gradually, corresponding to the increase of clay minerals and decrease of the carbonates. The δ30SiSPM values( 1.1‰ to 0.3‰) of the Yangtze SPM are similar to those of the average shale, but lower than those of the granite rocks( 0.3‰ to 0.3‰), reflecting the effect of silicon isotope fractionation in silicate weathering process. The δ30SiSPM values of the Yangtze SPM show a decreasing trend from the upper to the middle and lower reaches, responding to the variation of the clay content. The major anions of the river water are HCO 3, SO 4 2, Cl, NO 3, SiO 4 4 and F and the major cations include Ca2+, Na+, Mg2+, K+ and Sr2+. The good correlation between HCO3-content and the content of Ca2+may suggest that carbonate dissolution is the dominate contributor to the total dissolved solid(TDS) of the Yangtze River. Very good correlations are also found among contents of Cl, SO4 2, Na+, Mg2+, K+and Sr2+, indicating the important contribution of evaporite dissolution to the TDS of the Yangtze River. High TDS contents are generally found in the head water, reflecting a strong effect of evaporation in the Qinghai-Tibet Plateau. A small increase of the TDS is generally observed in the river mouth, indicating the influence of tidal intrusion. The F and NO3 contents show a clear increase trend from the upstream to downstream, reflecting the contribution of pesticides and fertilizers in the Chuan Jiang section and the middle and lower reaches. The DSi shows a decrease trend from the upstream to downstream, reflecting the effect of rice and grass growth along the Chuan Jiang section and the middle and lower reaches. The dissolved Cu, Zn and Cd in the Yangtze water are all higher than those in world large rivers, reflecting the effect of intensive mining activity along the Yangtze drainage area. The Yangtze water generally shows similar REE distribution pattern to the global shale. The δ30SiDiss values of the dissolved silicon vary from 0.5‰ to 3.7‰, which is the highest among those of the rivers studied. The δ30SiDiss values of the water in the Yangtze mainsteam show an increase trend from the upper stream to downstream. Its DSi and δ30SiDiss are influenced by multiple processes, such as weathering process, phytolith growth in plants, evaporation, phytolith dissolution, growth of fresh water diatom, adsorption and desorption of aqueous monosilicic acid on iron oxide, precipitation of silcretes and formation of clays coatings in aquifers, and human activity. The δ34SSO4 values of the Yangtze water range from 1.7‰ to 9.0‰. The SO4 in the Yangtze water are mainly from the SO4 in meteoric water, the dissolved sulfate from evaporite, and oxidation of sulfide in rocks, coal and ore deposits. The sulfate reduction and precipitation process can also affect the sulfur isotope composition of the Yangtze water. The87Sr/86Sr ratios of the Yangtze water range from 0.70823 to 0.71590, with an average value of 0.71084. The87Sr/86Sr ratio and Sr concentration are primary controlled by mixing of various sources with different87Sr/86Sr ratios and Sr contents, including the limestone, evaporite and the silicate rocks. The atmospheric precipitation and anthropogenic inputs can also contribute some Sr to the river. The δ11B values of the dissolved B in the Yangtze water range from 2.0‰ to 18.3‰, which is affected by multifactors, such as silicate weathering, carbonate weathering, evaporite dissolution, atmospheric deposition, and anthropogenic inputs. | DING Tiping GAO Jianfei TIAN Shihong SHI Guoyu CHEN Feng WANG Chengyu LUO Xurong HAN Dan | 2014 | Acta Geologica Sinica(English Edition)2014，88，1： | 10 |
| 5 | An Overview of China's Mainland Temperature Change Research显示文摘There has been significant effort devoted to investigating long-term trends in land surface air temperature over China's Mainland by Chinese scientists over the past 50 years, and much progress has been made in understanding dynamics of the changes. This review highlights research conducted by early Chinese climatologists, and particularly Professor Shaowu Wang from Peking University, with special focus on systematic work that has been conducted since the mid to late 1970s. We also discuss major issues that remain unresolved in past and current studies. The most recent analyses indicate that the country-average annual mean surface air temperature rose by 1.12℃ over the past 115 years(1901–2015), with a rate of increase of about 0.10℃ decade^(-1). Temperatures have risen more rapidly since the 1950s, with the rate of increase of more than 0.25℃ decade^(-1). However, the recent increase in temperatures is in large part due to contamination by systematically biased data. These data are influenced by unprecedented urbanization in China, with a contribution of urbanization to the overall increase of annual mean temperatures in China's Mainland of about one third over the past half a century. If the bias is corrected, the rate of increase for the country-average annual mean surface air temperature is 0.17℃ decade^(-1) over the last 50–60 years, which is approximately the same as global and Northern Hemispheric averages in recent decades. Future efforts should be focused towards the recovery and digitization of early-year observational records, the homogenization of observational data, the evaluation and adjustment of urbanization bias in temperature data series from urban stations, the analysis of extreme temperatures over longer periods including the first half of the 20th century, and the investigation of the observed surface air temperature change mechanisms in China's Mainland. | Guoyu REN Yihui DING Guoli TANG | 2017 | Journal of Meteorological Research2017，31，1： | 9 |
| 6 | Design and Performance of an Improved Trapped Vortex Combustor显示文摘A trapped vortex combustor (TVC) has been a very promising novel concept for it offers improvements in lean blow out, altitude relight, operating range, as well as a potential to decrease NOx emissions compared to conventional combustors. The present paper discusses the improved designs of the new combustor over the prior ones of our research group, including that:a) the over-all dimensions, both axial and radial, are reduced to those of an actual aero-engine combustor; b) the air flow distribution is optimized, and especially 15% of the air is fed into the liner as cooling air; c) a straight-wall diffuser with divergence angle 9°is added. A series of experiments (cavity-fueled only, under atmospheric pressure) has been conducted to investigate the performance of the improved TVC. Experimental results show that at the inlet temperature of 523 K, the inlet pressure of 0.1 MPa, stable operation of the TVC test rig is observed for the Mach number 0.15-0.34, indicating good flame stability; the combustion efficiency obtained in this paper falls into the range of 60%-96%; as the total excess air ratio increases, the combustion efficiency decreases, while the increase of the inlet temperature is beneficial to high combustion efficiency; besides, the optimal Mach numbers for high combustion efficiency under different inlet conditions are confirmed. The outlet temperature profiles feature a bottom in the midheight of the exit. This paper demonstrates the feasibility for the TVC to be applied to a realistic aero-engine preliminarily and provides reference for TVC design. | JIN Yi HE Xiaomin JIANG Bo WU Zejun DING Guoyu | 2012 | Chinese Journal of Aeronautics2012，25，6： | 8 |
| 7 | Thickness of calcium carbonate coats on stones of the Heishanxia terraces of the Yellow River and dating of coarse clastic sedimentary geomorphic surfaces显示文摘The calcium carbonate coats on stones developed in soil on the geomorphic surfaces of coarse clastic sediments in arid-semiarid regions contain evident information of age. The thickness of coats can be used not only as a good age indicator for the geomorphic surfaces but also coats themselves can be directly used as dating materials in the ESR method. Through measuring the thickness of carbonate coats on stones in soils on the alluvial terraces in the mouth of the Heishanxia gorge of the Yellow River and ESR dating of layers separated from the carbonate coats, the average of accumulation rates of the thickness of carbonate coats on stones since 1.57 Ma was calculated to be 0.10 mm/ka in the studied area, and a regression equation between carbonate coat thickness and age was also generated. From these research results, ages of T2-T11 terraces of the Yellow River in the studied area were systematically determined, and their values are in turn 18 ka, 94 ka, 139 ka, 215 ka, 305 ka, 410 ka, 495 ka, 742 ka, | Chengqi Xing Gongming Yin Guoyu Ding Yanchou Lu Xuhui Shen Qinjian Tian Zhizhang Chai Kaibo Wei | 2002 | Chinese Science Bulletin2002，47，19： | 7 |
| 8 | An investigation on a novel PDLC film's fabrication and its electro-optical properties显示文摘A polymer dispersed liquid crystal (PDLC) film that has good electro-optical properties is produced by the method of polymerized-induced phase separation. Based on the application foreground, its capability parameters, such as contrast ratio, work voltage, and visual angle, are characterized for the first time by a white light but not a fixed wavelength light. The results show the PDLC film has a low work-voltage of 20 V, more than 150° visual angle, high stability, and long lifetime. The differences between plastic and glass ITO-coated substrates of PDLC films are also studied in this paper. The plastic substrate has better property and will have a wider perspective especially in the portable, tender and folded display devices. Due to adjustable properties of film by electric field, PDLC has the potential application for display device, sensor, switch, grating, and new generation analytical apparatus. | DING HongLiu, ZHAO Ting, CHENG YuXiao, PANG YueHong, XU He, SHI GuoYue & JIN LiTong Chemistry Department of East China Normal University, Shanghai 200062, China | 2007 | Science China Chemistry2007，50，3： | 2 |
| 9 | On-line near-infrared spectroscopy optimizing and monitoring biotransformation process of γ-aminobutyric acid显示文摘Near-infrared spectroscopy(NIRS) with its fast and nondestructive advantages can be qualified for the real-time quantitative analysis.This paper demonstrates that NIRS combined with partial least squares(PLS) regression can be used as a rapid analytical method to simultaneously quantify L-glutamic acid(LGlu) and γ-aminobutyric acid(GABA) in a biotransformation process and to guide the optimization of production conditions when the merits of NIRS are combined with response surface methodology.The high performance liquid chromatography(HPLC) reference analysis was performed by the o-phthaldialdehyde pre-column derivatization.NIRS measurements of two batches of 141 samples were firstly analyzed by PLS with several spectral pre-processing methods.Compared with those of the HPLC reference analysis,the resulting determination coefficients(R^2),root mean square error of prediction(RMSEP) and residual predictive deviation(RPD) of the external validation for the L-Glu concentration were 99.5%,1.62 g/L,and11.3,respectively.For the GABA concentration,R^2,RMSEP,and RPD were 99.8%,4.00 g/L,and 16.4,respectively.This NIRS model was then used to optimize the biotransformation process through a BoxBehnken experimental design.Under the optimal conditions without p H adjustment,200 g/L L-Glu could be catalyzed by 7148 U/L glutamate decarboxylase(GAD) to GABA,reaching 99% conversion at the fifth hour.NIRS analysis provided timely information on the conversion from L-Glu to GABA.The results suggest that the NIRS model can not only be used for the routine profiling of enzymatic conversion,providing a simple and effective method of monitoring the biotransformation process of GABA,but also be considered to be an optimal tool to guide the optimization of production conditions. | Guoyu Ding Yuanyuan Hou Jiamin Peng Yunbing Shen Min Jiang Gang Bai | 2016 | Journal of Pharmaceutical Analysis2016，6，3： | 2 |
| 10 | Late Cenozoic Stratigraphic Sequence and Its Implication to Tectonic Evolution, Hejiakouzi Area, Ningxia Hui Autonomous Region显示文摘The Late Cenozoic stratigraphic sequence and its information of tectonic evolution are obtained here through the detailed petrostratigraphic and magnetostratigraphic study and research of stratigraphic contact and sedmentary faces of the Cenozoic strata profile, Hejiakouzi area, Ningxia Hui Autonomous Region. The intense Cenozoic tectonic deformation began at 10Ma BP in the Haiyuan-Tongxin Syntaxis, the northeastern margin of Qinghai-Xizang Plateau, and a few deformation events occurred during Late Cenozoic Era. | Shen Xuhui, Tian Qinjian, Ding Guoyu, Wei Kaibo, and Chen ZhengweiCenter for Analysis and Prediction, China Seismological Bureau, Beijing 100036, ChinaChai ChizhangSeismological Bureau of Ningxia Hui Autonomous Region, Yinchuan 750001, China | 2001 | Earthquake Research in China2001，15，4： | 2 |
| 11 | Two-stage least squares basediterative identification algorithm for controlled autoregressive mov-ing average (CARMA) systems 显示文摘 | YAO GUOYU?DING RUIFENG | 2012 | Computers and Mathematicswith Applications2012，，63： | 1 |
| 12 | Detection,causes and projection of climate change over China:An overview of recent progress显示文摘 | Ding Yihui Ben Guoyu Zhao Zongci | 2007 | Advances in Atmospheric Science2007，24，6： | 1 |
| 13 | Comparative Analysis of China Surface Air Temperature Series for the Past 100 Years显示文摘温度变化在全球变化科学起一个关键作用。在过去的几十年,全面调查结果在中国在温度变化上被完成过去的 100 年了。几个次系列被创造了为这个国家说明平均表面空气温度。这些的关联从 0.73 ~ 0.97 的系列范围。它也在更好的数据质量,更宽的空间数据范围,时间系列的改进同质,和调查结果的提高的可靠性被完成。结果由 0.78 摮爠獥潰獮獥琠? 汣浩瑡 ? 档湡敧 ? 湩汦敵据獥漠 ? 牣潹灳敨楲? 档湡敧 ? 愠摮愠慤瑰瑡潩 ? | Guoli Tang Yihui Ding Shaowu Wang Guoyu Ren Hongbin Liu Li Zhang | 2010 | Advances in Climate Change Research2010，1，1： | 1 |
| 14 | Active faults and magnitudes of left-lateral displacement along the northern margin of the Tibetan Plateau显示文摘 | Ding Guoyu Chen Jie Tian Qinjian | 2004 | Tectonophysics2004，380，34： | 1 |
| 15 | NPC1-regulated dynamic of clathrin-coated pits is essential for viral entry显示文摘Viruses utilize cellular lipids and manipulate host lipid metabolism to ensure their replication and spread.Therefore,the identification of lipids and metabolic pathways that are suitable targets for antiviral development is crucial.Using a library of compounds targeting host lipid metabolic factors and testing them for their ability to block pseudorabies virus(PRV)and vesicular stomatitis virus(VSV)infection,we found that U18666A,a specific inhibitor of Niemann-Pick C1(NPC1),is highly potent in suppressing the entry of diverse viruses including pseudotyped severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).NPC1 deficiency markedly attenuates viral growth by decreasing cholesterol abundance in the plasma mem-brane,thereby inhibiting the dynamics of clathrin-coated pits(CCPs),which are indispensable for clathrin-mediated endocytosis.Significantly,exogenous cholesterol can complement the dynamics of CCPs,leading to efficient viral entry and infectivity.Administration of U18666A improves the survival and pathology of PRV-and influenza A virus-infected mice.Thus,our studies demonstrate a unique mechanism by which NPC1 inhibition achieves broad antiviral activity,indicating a potential new therapeutic strategy against SARS-CoV-2,as well as other emerging viruses. | Guoli Li Bingqian Su Pengfei Fu Yilin Bai Guangxu Ding Dahua Li Jiang Wang Guoyu Yang Beibei Chu | 2022 | Science China(Life Sciences)2022，65，2： | 1 |
| 16 | QTL detection of seven spike-related traits and their genetic correlations in wheat using two related RIL populations显示文摘 | Fa Cui Anming Ding Jun Li Chunhua Zhao Lin Wang Xiuqin Wang Xiaolei Qi Xingfeng Li Guoyu Li Jurong Gao Honggang Wang | 2012 | Euphytica2012，，1： | 1 |
| 17 | The characteristics of active fault behaviors and earthquakes in China mainland显示文摘 | Ding Guoyu | 1992 | Journal of Earthquake Prediction1992，1，1： | 1 |
| 18 | Expression of vascular cell adhesion molecule-1 facilitates angiogenesis in gastric carcinoma显示文摘Objective: To investigate the relationship between the expression of VCAM-1 and oncogenesis, tumor angiogenesis and metastasis in gastric carcinoma. Methods: Using RT-PCR and immunohistochemistry technique, the expression of VCAM-1 were detected in specimens from 44 patients with gastric cancer, 8 with ulcer. Microvessel density(MVD) was also counted by endothelial cells immunostained with monoclonal antibodies CD34. In addition, Circulating sVCAM-1 concentrations were measured by an enzyme linked immunosorbent assay. Results:Of 44 gastric cancer tumor tissues, 36 were detected the expressions of VCAM-1 mRNA. The rates of VCAM-1 mRNA in the primary gastric cancer tissues were significantly higher than those in the para-cancerous tissues and benign ulcer tissues(P < 0.05). The VCAM-1 posithoseive isolates had more lymph node metastases than that of VCAM-1-negative ones(P < 0.05). MVD of positive VCAM-1 expression tissues were higher than those of negative VCAM-1(P < 0.05). Circulating sVCAM-1 levels decreased significantly after operation(P < 0.05). Furthermore, the levels of sVCAM-1 were positively correlated with the expressions of VCAM-1 in the tumor tissues(r = 0.64, P < 0.05). Conclusion: Expressions of VCAM-1 mRNA was closely related to oncogenesis, tumor angiogenesis and metastasis in gastric carcinoma. The concentration of sVCAM-1 may be considered as an effective mark of tumor burden of gastric cancer. | Yongbin Ding Tianson Xia Guoyu Chen Jianguo Xia | 2006 | Journal of Nanjing Medical University2006，20，6： | 1 |
| 19 | Seismotectonic Study on the West Part of the Interaction Zone Between Southern Tianshan and Northern Tarim显示文摘The interaction zone between southern Tianshan and northern Tarim is located at the northeast side of Pamir. It is a region with high seismicity. We constructed a seismotectonic model for the west part of this zone from geological profiles, deep crust seismic detection and earthquake focal mechanisms data. Based on the synthesized geological features, deep crust structure, and earthquake focal mechanisms, we think that the main regional tectonic feature is that the Tianshan tecto-lithostratigraphic unit overthrusts on the Tarim block. The Tianshan tectonic system includes the Maidan fault and thrust sheets in front of the fault; The Tarim tectonic system includes the underground northern Tarim margin fault, conjugate faults in basement and overthrust fault in shallow. The northern Tarim margin fault is a high angle fault deep in the Tarim crust, adjusting different trending deformation between Tianshan and Tarim. It is a major active fault that can generate large earthquakes. The other faults, such as the Tianshan overthrust system and the Tarim basement faults in this area may generate moderately strong earthquakes with different styles. | Tian Qinjian Ding Guoyu Hao Ping | 2007 | Earthquake Research in China2007，21，1： | 0 |
| 20 | Pull-apart Basins and the Total Lateral Displacement Along the Haiyuan Fault Zone in Cenozoic显示文摘Pull-apart basins of three scales were found along the Haiyuan fault zone. The largest one is more than 50km long, named Laolongwan basin developed in Miocene. A model was built to calculate the amount of pull-apart of an extensional basin. Parameters used in calculation include thickness and length of deposition and depth of detachment. The results of calculation show that the amount of pull-apart of the Laolongwan Basin is about 30 km. Based on previous studies and calculating by using the average slip rate method, amount of pull-apart of the other two smaller basins are 22 km and 8 km, respectively. Thus, the total displacement of strike-slip along the Haiyuan fault zone is about 60 km, which is close to the offset of the Yellow River from Jingtai to Jingyuan. | Tian Qinjian, Ding Guoyu, and Shen XuhuiCenter for Analysis and Prediction, China Seismological Bureau, Beijing 100036, China | 2001 | Earthquake Research in China2001，15，4： | 0 |
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