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3篇 您的检索式:作者名="DU Zhenbao"
    题名 作者 年代 出处 被引量
1Sub-lethal effects of four neonicotinoid seed treatments on the demography and feeding behaviour of the wheat aphid Sitobion avenae 显示文摘MIAO Jin DU Zhenbao WU Yuqing 2014Pest Manag Sci2014,70,1:1
2Seismic performance evaluation of VCFPB isolated storage tank using real-time hybrid simulation显示文摘Variable curvature friction pendulum bearings(VCFPB)effectively reduce the dynamic response of storage tanks induced by earthquakes.Shaking table testing is used to assess the seismic performance of VCFPB isolated storage tanks.However,the vertical pressure and friction coefficient of the scaled VCFPB in the shaking table tests cannot match the equivalent values of these parameters in the prototype.To avoid this drawback,a real-time hybrid simulation(RTHS)test was developed.Using RTHS testing,a 1/8 scaled tank isolated by VCFPB was tested.The experimental results showed that the displacement dynamic magnification factor of VCFPB,peak reduction factors of the acceleration,shear force,and overturning moment at bottom of the tank,were negative exponential functions of the ratio of peak ground acceleration(PGA)and friction coefficient.The peak reduction factors of displacement,acceleration,force and overturning moment,which were obtained from the experimental results,are compared with those calculated by the Housner model.It can be concluded that the Housner model is applicable in estimation of the acceleration,shear force,and overturning moment of liquid storage tank,but not for the sliding displacement of VCFPBs.Hong Yue Tang Zhenyun Li Zhenbao Du Xiuli 2022Earthquake Engineering and Engineering Vibration2022,21,2:0
3CRISPR/Cas9 systems:Delivery technologies and biomedical applications显示文摘The emergence of the clustered regularly interspaced short palindromic repeats(CRISPR)/CRISPR-associated protein 9(Cas9)genome-editing system has brought about a significant revolution in the realm of managing human diseases,establishing animal models,and so on.To fully harness the potential of this potent gene-editing tool,ensuring efficient and secure delivery to the target site is paramount.Consequently,developing effective delivery methods for the CRISPR/Cas9 system has become a critical area of research.In this review,we present a comprehensive outline of delivery strategies and discuss their biomedical applications in the CRISPR/Cas9 system.We also provide an indepth analysis of physical,viral vector,and non-viral vector delivery strategies,including plasmid-,mRNA-and protein-based approach.In addition,we illustrate the biomedical applications of the CRISPR/Cas9 system.This review highlights the key factors affecting the delivery process and the current challenges facing the CRISPR/Cas9 system,while also delineating future directions and prospects that could inspire innovative delivery strategies.This review aims to provide new insights and ideas for advancing CRISPR/Cas9-based delivery strategies and to facilitate breakthroughs in biomedical research and therapeutic applications.Yimin Du Yanfei Liu Jiaxin Hu Xingxing Peng Zhenbao Liu 2023Asian Journal of Pharmaceutical Sciences2023,18,6:0
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