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| 1 | Beclin 1 augmented cis -diamminedichloroplatinum induced apoptosis via enhancing caspase-9 activity显示文摘 | Daisuke Furuya Naoki Tsuji Atsuhito Yagihashi Naoki Watanabe | 2005 | Experimental Cell Research2005,,: | 2 |
| 2 | Sessile serrated adenoma detection rate is correlated with adenoma detection rate显示文摘AIM To investigated the association between adenoma detection rate(ADR) and sessile serrated ADR(SSADR) and significant predictors for sessile serrated adenomas(SSA) detection.METHODS This study is a retrospective, single-center analysis. Total colonoscopies performed by the gastroenterologists at the University of Tokyo Hospital between January and December 2014 were retrospectively identified. Polyps were classified as low-grade or high-grade adenoma, cancer, SSA, or SSA with cytological dysplasia, and the prevalence of each type of polyp was investigated. Predictors of adenoma and SSA detection were examined using logistic generalized estimating equation models. The association between ADR and SSADR for each gastroenterologist was investigated by calculating a correlation coefficient weighted by the number of each gastroenterologist's examination.RESULTS A total of 3691 colonoscopies performed by 35 gastroenterologists were assessed. Overall, 978 (26.5%) low-and 84 (2.2%) high-grade adenomas, 81 (2.2%) cancers, 66 (1.8%) SSAs, and 2 (0.1%) SSAs with cytological dysplasia were detected. Overall ADR was 29.5%(men 33.2%, women 23.8%) and overall SSADR was 1.8%(men 1.7%, women 2.1%). In addition, 672 low-grade adenomas (68.8% of all the detected lowgrade adenomas), 58 (69.9%) high-grade adenomas, 29 (34.5%) cancers, 52 (78.8%) SSAs, and 2 (100%) SSAs with cytological dysplasia were found in the proximal colon. Adenoma detection was the only significant predictor of SSA detection (adjusted OR: 2.53, 95%CI: 1.53-4.20; P < 0.001). The correlation coefficient between ADR and SSADR weighted by the number of each gastroenterologist's examinations was 0.606(P < 0.001).CONCLUSION Our results demonstrated that ADR is correlated to SSADR. In addition, patients with adenomas had a higher prevalence of SSAs than those without adenomas. | Daisuke Ohki Yosuke Tsuji Tomohiro Shinozaki Yoshiki Sakaguchi Chihiro Minatsuki Hiroto Kinoshita Keiko Niimi Satoshi Ono Yoku Hayakawa Shuntaro Yoshida Atsuo Yamada Shinya Kodashima Nobutake Yamamichi Yoshihiro Hirata Tetsuo Ushiku Mitsuhiro Fujishiro Masashi Fukayama Kazuhiko Koike | 2018 | World Journal of Gastrointestinal Oncology2018,10,3: | 2 |
| 3 | Detection of autoantibodies to livin and survivin in Sera from lung cancer patients显示文摘 | Atsuhito Yagihashi Koichi Asanuma Daisuke Kobayashi Naoki Tsuji Yasuharu Shijubo Shosaku Abe Yoshihiko Hirohashi Toshihiko Torigoe Noriyuki Sato Naoki Watanabe | 2004 | Lung Cancer2004,,2: | 1 |
| 4 | Reaction Mechanism of Metal Silicide Mg2Si for Li Insertion显示文摘 | Toshihiro Moriga Kozo Watanabe Daisuke Tsuji | 2000 | Journal of Solid State Chemistry2000,,153: | 1 |
| 5 | Mutations of the p53 Gene and Loss of Heterozygosity at Chromosome 17p13.1 are Associated with Increased Survivin Expression in Breast Cancer显示文摘 | Naoki Tsuji Kaori Furuse Koichi Asanuma Momoko Furuya Kei Kondoh Chinatsu Kamagata Masateru Sasaki Daisuke Kobayashi Atsuhito Yagihashi Hiroshi Takahashi Naoki Watanabe | 2004 | Breast Cancer Research and Treatment2004,,1: | 1 |
| 6 | Formability of ultrafine-grained interstitial-free steel fabricated by accumulative roll-bonding and subsequent annealing显示文摘 | Rika Yoda Kosuke Shibata Takatoshi Morimitsu Daisuke Terada Nobuhiro Tsuji | 2011 | Scripta Materialia2011,,3: | 1 |
| 7 | Relationship of lower uterine segment cancer with Lynch syndrome: Anovel case with an hMLH1 germline mutation显示文摘 | Kenta Masuda Kouji Banno Akira Hirasawa Megumi Yanokura Kosuke Tsuji Yusuke Kobayashi Iori Kisu Arisa Ueki Hiroyuki Nomura Eiichiro Tominaga Nobuyuki Susumu Daisuke Aoki | 2012 | Oncology Reports2012,,5: | 1 |
| 8 | Diagnostic relevance of overexpressed Nanog gene in early lung cancers显示文摘 | Shinya Nirasawa Daisuke Kobayashi Naoki Tsuji Kageaki Kuribayashi Naoki Watanabe | 2009 | Oncology Reports2009,,3: | 1 |
| 9 | Fast quench of superconducting wire by pulsed current and its application to pulsed power generation 显示文摘 | Junya Suehiro Kouichi Tsulsumi Daisuke Tsuji | 1999 | IEE Conference Publication1999,5,467: | 1 |
| 10 | Strain-dependence of deformation microstructures in ultra-low-C IF steel deformed to high strains by torsion at elevated temperatures显示文摘Single-phase bcc-ferrite in an interstitial free(IF)steel was deformed to different strains in a wide range from low to high strains(ε=1–7)by torsion under different Zener-Hollomon(Z)conditions.The specimens were rapidly quenched after the torsion to preserve microstructures formed under different deformation conditions.The results showed that during high-Z(low-temperature)deformation,grains were subdivided by geometrically necessary boundaries(GNBs)via the grain subdivision mechanism.Deformation to high strains(ε>5)led to the ultrafine lamellar structures(with grain sizes<1μm)mainly composed of GNBs having high misorientation angles.Decreasing Z with increasing temperature and/or decreasing strain rate accelerated thermally activated processes,such as dynamic recovery and boundary migration.Unlike the ultrafine lamella formed under the high-Z condition,a variety of microstructures having equiaxed morphologies with fine to coarse grain sizes(>1μm)were realized with decreasing Z.The significance of the grain subdivision and the thermally activated phenomena on the formation of various microstructures under different deformation conditions is discussed. | Reza Gholizadeh Daisuke Terada Akinobu Shibata Nobuhiro Tsuji | 2020 | Nano Materials Science2020,2,1: | 1 |
| 11 | Micro- structure and mechanical properties of commercial purity titanium severely deformed by ARB process 显示文摘 | Daisuke Terada Seiya Inoue Nobuhiro Tsuji | 2007 | Journal of Materials Science2007,42,5: | 1 |
| 12 | Survivin plays as a resistant factor against tamoxifen-induced apoptosis in human breast cancer cells显示文摘 | Ryosuke Moriai Naoki Tsuji Mikako Moriai Daisuke Kobayashi Naoki Watanabe | 2009 | Breast Cancer Research and Treatment2009,,2: | 1 |
| 13 | ‘Working’ cardiomyocytes exhibiting plateau action potentials from human placenta-derived extraembryonic mesodermal cells显示文摘 | Kazuma Okamoto Shunichiro Miyoshi Masashi Toyoda Naoko Hida Yukinori Ikegami Hatsune Makino Nobuhiro Nishiyama Hiroko Tsuji Chang-Hao Cui Kaoru Segawa Taro Uyama Daisuke Kami Kenji Miyado Hironori Asada Kenji Matsumoto Hirohisa Saito Yasunori Yoshimura Sa | 2007 | Experimental Cell Research2007,,12: | 1 |
| 14 | Formability of ultrafine-grained interstitial-free steel fabricated by accumulative roll-bonding and subsequent annealing显示文摘 | Rika Yoda Kosuke Shibata Takatoshi Morimitsu Daisuke Terada Nobuhiro Tsuji | 2011 | Scripta Materialia2011,,3: | 1 |
| 15 | Microstructure and mechanical properties of commercial purity titanium severely deformed by ARB process显示文摘 | Daisuke Terada Seiya Inoue Nobuhiro Tsuji | 2007 | Journal of Materials Science2007,,5: | 1 |
| 16 | Diagnostic relevance of overexpressed Nanog gene in early lung cancers显示文摘 | Shinya Nirasawa Daisuke Kobayashi Naoki Tsuji Kageaki Kuribayashi Naoki Watanabe | 2009 | Oncology Reports2009,,3: | 1 |
| 17 | Association between ADAMTS13 activity-VWF antigen imbalance and the therapeutic effect of HAIC in patients with hepatocellular carcinoma显示文摘BACKGROUND Prediction of HAIC treatment response is important for improving the prognosis in patients with hepatocellular carcinoma(HCC).The progression of HCC is related to hypercoagulability and angiogenesis.It is known that ADAMTS13 and von Willebrand factor(VWF)are related to hypercoagulability.In addition,previous study reported that the association between ADAMTS13 and VWF,and angiogenesis via vascular endothelial growth factor(VEGF).Recently,ADAMTS13 and VWF have been associated with the prognosis in patients with various kinds of cancer undergoing chemotherapy.AIM To investigate whether ADAMTS13 and VWF become useful biomarkers of treatment response in HCC patients before the initiation of HAIC treatment.METHODS Seventy-two patients were enrolled in this study.ADAMTS13 activity(ADAMTS13:AC),VWF antigen(VWF:Ag)and VEGF levels were determined via enzyme-linked immunosorbent assay.Univariable and multivariable analyses were performed to determine the predictive factors of treatment response in patients with HCC undergoing HAIC treatment.RESULTS ADAMTS13:AC levels in HCC patients with stable disease(SD)+partial response(PR)of HAIC treatment were significantly higher than those with progressive disease(PD)(P<0.05).In contrast,VWF:Ag/ADAMTS13:AC ratio and VEGF levels in HCC patients with SD+PR were significantly lower than those with PD(both P<0.05).Patients with high VWF:Ag/ADAMTS13:AC ratio(>2.7)had higher VEGF levels than those with low ratio(≤2.7).Multivariable analysis revealed that VWF:Ag/ADAMTS13:AC ratio was a predictive factor of HAIC treatment response.CONCLUSION VWF:Ag/ADAMTS13:AC ratio may become a useful biomarker of treatment response in HCC patients before the initiation of HAIC treatment. | Hiroaki Takaya Tadashi Namisaki Kei Moriya Naotaka Shimozato Kosuke Kaji Hiroyuki Ogawa Koji Ishida Yuki Tsuji Daisuke Kaya Hirotestu Takagi Yukihisa Fujinaga Norihisa Nishimura Yasuhiko Sawada Hideto Kawaratani Takemi Akahane Masanori Matsumoto Hitoshi Yoshiji | 2020 | World Journal of Gastroenterology2020,26,45: | 0 |