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| 1 | 肛裂临床诊治指南(第三次修订)显示文摘“美国结直肠外科医师协会(American Societyof ColonandRectal Surgeons.ASCRS)”(协会)致力于推进结直肠和肛门疾病的相关理论以及预防和诊疗水平的提高,给患者提供优质的医疗服务。“标准委员会”由协会中在结直肠外科方面有显著专长的成员组成。该委员会的建立是为了引领国际结直肠和肛门疾病诊治的发展,以建立具有循证医学证据的临床诊疗指南。指南是涵盖性的,非指令性的,目的是为临床决策提供信息,而非具体的治疗方法。指南适用于所有相关的医护人员以及希望得到相应指南中疾病的相关诊治信息的患者。 | Farshid Araghizadeh ~ Robin Boushey Sridhar Chalasani George Chang Robert Cima Gary Dunn Daniel Feingold Philip Fleshner Daniel Geisler Jill Genua Sharon Gregorcyk Daniel Herzig Andreas Kaiser Ravin Kumar David Larson Steven Mills John Monson P. Terry Phang Feza Remzi David Rivadeneira Howard Ross Peter Senatore Elin Sigurdson Thomas Stahl Scott Steele Scott Strong Charles Tement Judith Trudel Madhulika Varnna Martin Weiser 丁义江(译) 皇甫少华(译) 丁曙晴(译) | 2013 | 中华胃肠外科杂志2013,16,7: | 70 |
| 2 | 氯吡格雷的使用与药物洗脱支架植入后远期临床结果显示文摘背景:近来的冠状动脉内药物洗脱支架研究提示,现行的抗血小板治疗方案可能并不足以预防后期支架内血栓形成。目的:于接受药物洗脱支架(drug-eluting stents,DESs)和裸金属支架(bare-metal stents,BMSs)治疗的冠状动脉病患者中评估氯吡格雷使用与患者远期结果的关系。设计、地点及患者:于连续患者中进行观察性研究。患者于2000年1月1日至2005年7月31日在杜克心脏治疗中心(一家位于北卡罗来纳州达累姆市的三级治疗中心)接受冠状动脉内支架治疗。于6、12、24个月时进行随访,直至2006年9月7日。研究人群包括4666例最初接受BMS(n=3165)或DES(n=1501)经皮冠状动脉介入治疗的患者。对随访6和12个月没有事件(没有死亡、心肌梗死或血管重建手术)的患者进行界标分析(landmark analysis)。在这些时间点上根据支架类型以及自我报告之氯吡格雷的使用情况将患者分为4组:DES使用氯吡格雷组、DES不用氯吡格雷组、BMS使用氯吡格雷组以及BMS不用氯吡格雷组。主要观测指标:随访24个月时死亡、非致命性心肌梗死以及死亡或心肌梗死之复合终点。结果:在6个月时没有事件发生的DES组患者(637例使用、579例未使用氯吡格雷)中,氯吡格雷的使用是随访24个月校正死亡率较低(使用2.0%比未使用5.3%;差异,-3.3%;95%CI,-6.3%至-0.3%;P=0.03)以及死亡或心肌梗死发生率较低(3.1%比7.2%;差异,-4.1%;95%CI,-7.6%至-0.6%;P=0.02)的显著预测指标。然而,在BMS组患者中(417例使用、1976例未用氯吡格雷),死亡(3.7%比4.5%;差异,-0.7%;95%CI,-2.9%至1.4%;P=0.50)以及死亡或心肌梗死发生率(5.5%比6.0%;差异,-0.5%;95%CI,-3.2%至2.2%;P:0.70)没有差异。在12个月随访没有事件发生的DES组患者(252例使用、276例未用氯吡格雷)中,氯吡格雷的使用依然可以预测24个月死亡(0%比3.5%;差异,-3.5%;95%CI,-5.9%至-1.1%;P=0.004)以及死亡或心肌梗死发生率(0%比4.5%;差异,-4.5%;95%CI,-7.1%至-1.9%;P〈0.001)较低。然而,在BMS组患者中(346例使用、1644例未用氯吡格雷),在死亡(3.3%比2.7%;差异,0.6%;95%CI,1.5%至2.8%;P=0.57)以及死亡或心肌梗死(4.7%比3.6%;差异,1.0%;95%CI,-1.6%至3.6%;P=0.44)发生方面,依然没有差异。结论:在接受DES治疗的患者中,延长氯吡格雷的使用可以使死亡以及死亡或心肌梗死的发生率下降。然而,使用氯吡格雷的适宜期限只能通过大型临床随机试验确定。 | Eric L Eisenstein, DBA Kevin J. Anstrom, PhD David F. Kong, MD Linda K. Shaw, MS Robert H. Tuttle, MSPH Daniel B. Mark, MD, MPH Judith M. Kramer, MD, MS Robert A. Harrington, MD David B. Matchar, MD David E. Kandzari, MD 1 Eric D. Peterson, MD, MPH Kevin A. Schulman, MD Robert M. Califf, MD 李呈亿(译) David E. Kandzari, MD | 2007 | 美国医学会杂志(中文版)2007,26,3: | 60 |
| 3 | 婴幼儿卒中的处理:来自美国心脏协会卒中委员会和青少年心血管病委员会专门写作组的科学声明显示文摘目的:本声明旨在回顾有关儿童卒中的文献,为最佳的诊断和治疗提供推荐意见,供负责诊断和治疗婴儿、儿童和青少年脑血管病的医生使用。方法:写作组成员由美国心脏协会卒中委员会科学声明监督委员会任命,由多个不同领域的专家组成。应用美国心脏协会卒中委员会的证据分级标准对每条推荐意见进行分级。在经过小组成员审查后,草稿由4位同行评议专家和卒中委员会指导委员会成员审阅,并由美国心脏协会科学咨询和协调委员会批准。我们预计该声明需在4年内进行更新。结果:为镰状细胞病、烟雾病、颈一脑动脉夹层分离和心源性栓塞引起的缺血性卒中的预防提供循证推荐,同时为出血性卒中的评价和处理提供推荐意见。提出儿童使用肝素和华法林的剂量方案。另外,还为围产期卒中和儿童脑静脉窦血栓形成的评价和处理提供推荐。 | E.Steve Roach(著) Meredith R. Golomb(著) Robert Adams(著) Jose Biller(著) Stephen Daniels(著) Gabrielle deVeber(著) Donna Ferriero(著) Blaise V. Jones(著) Fenella J. Kirkham(著) R. Michael Scott(著) Edward R. Smith(著) 刘丽芳(译) 王胜男(译) 王伟(译) 林镇洲(译) 朱佳佳(译) 潘速跃(译) | 2008 | 国际脑血管病杂志2008,16,11: | 60 |
| 4 | Spatial cloud computing: how can the geospatial sciences use and help shape cloud computing?显示文摘The geospatial sciences face grand information technology(IT)challenges in the twenty-first century:data intensity,computing intensity,concurrent access intensity and spatiotemporal intensity.These challenges require the readiness of a computing infrastructure that can:(1)better support discovery,access and utilization of data and data processing so as to relieve scientists and engineers of IT tasks and focus on scientific discoveries;(2)provide real-time IT resources to enable real-time applications,such as emergency response;(3)deal with access spikes;and(4)provide more reliable and scalable service for massive numbers of concurrent users to advance public knowledge.The emergence of cloud computing provides a potential solution with an elastic,on-demand computing platform to integrateobservation systems,parameter extracting algorithms,phenomena simulations,analytical visualization and decision support,and to provide social impact and user feedbackthe essential elements of the geospatial sciences.We discuss the utilization of cloud computing to support the intensities of geospatial sciences by reporting from our investigations on how cloud computing could enable the geospatial sciences and how spatiotemporal principles,the kernel of the geospatial sciences,could be utilized to ensure the benefits of cloud computing.Four research examples are presented to analyze how to:(1)search,access and utilize geospatial data;(2)configure computing infrastructure to enable the computability of intensive simulation models;(3)disseminate and utilize research results for massive numbers of concurrent users;and(4)adopt spatiotemporal principles to support spatiotemporal intensive applications.The paper concludes with a discussion of opportunities and challenges for spatial cloud computing(SCC). | Chaowei Yang Michael Goodchild Qunying Huang Doug Nebert Robert Raskin Yan Xu Myra Bambacus Daniel Fay | 2011 | International Journal of Digital Earth2011,4,4: | 55 |
| 5 | 美国临床生化科学院检验医学实践指南:睾丸、前列腺、结直肠、乳腺及卵巢癌肿瘤标志物的应用显示文摘经美国临床生化科学院(NCAB)授权,由鄢盛恺教授组织学者、专家翻译审定2009年NCAB检验医学实践指南:睾丸、前列腺、结直肠、乳腺及卵巢癌中肿瘤标志物的应用单行本(Catharine M.Sturgeon教授和Eleftherios P.Diaman-dis教授编辑)。该指南包含第1至6章共6部分内容,参加指南制订的专家阵容强大,分别从临床及检验角度对睾丸、前列腺、结直肠、乳腺及卵巢癌中肿瘤标志物的检测与临床应用方面的问题进行了详细阐述与说明,是目前国内外在肿瘤实验诊断方面的纲领性应用文件。不仅适合广大检验人员、临床医护人员学习使用,也非常适合相关仪器试剂生产厂商研发应用。本指南由刘洋、薛丽、林文涛、李江、梁红艳、顾兵、潘世扬、郑磊等翻译,姜晓峰、沈文梅、田亚平、鄢盛恺审校,最后由鄢盛恺统稿审定。本指南的翻译出版,不仅有助于我国检验人员和医护人员合理的检测和应用睾丸、前列腺、结直肠、乳腺及卵巢癌肿瘤标志物,对我国检验医学指南的编写与应用也有一定的借鉴作用。本刊特在本期刊发,以飨广大读者。 | 鄢盛恺 Ulf-Hkan Stenman Rolf Lamerz Leendert H.Looijenga Nils Brünner Michael J.Duffy Caj Haglund Mads Holten-Andersen Hans JФrgen Nielsen Francisco J.Esteva Nadia Harbeck Daniel F.Hayes Rafael Molina Daniel W.Chan Robert C.Bast Jr Ie-Ming Shih Lori J.Sokoll Gyrgy Slétormos 刘洋 梁红艳 姜晓峰 田亚平 薛丽 林文涛 顾兵 潘世扬 沈文梅 郑磊 李江 | 2012 | 临床检验杂志2012,30,2: | 32 |
| 6 | Twelve weeks of dance exergaming in overweight and obese adolescent girls:Transfer effects on physical activity,screen time,and self-efficacy显示文摘Background: Given the low levels of physical activity(PA) among adolescent girls in the US, there is a need to identify tools to motivate increased PA. Although there is limited evidence that adolescents transfer PA from one context to another, exergames(i.e., video games that require gross motor activity) may act as a gateway to promote overall PA outside game play. The purpose of this study was to examine potential transfer effects(i.e., influences on external behaviors and psychological constructs) of a 12-week exergaming intervention on adolescent girls' PA, screen time,and self-efficacy toward PA, as well as the intrinsic motivation of exergaming.Methods: Participants were 37 girls aged 14–18 years(65% African American, 35% white) who were overweight or obese(body mass index ≥ 85 th percentile) and were recruited from the community via school, physicians, news media, and social media websites. Adolescents were randomly assigned to a 12-week group exergaming intervention(thirty-six 60 min sessions of group-based dance exergaming in a research laboratory using Kinect for Xbox360(Microsoft Corporation, Redmond, WA, USA)) or to a no-treatment control group. Outcome variables included objectively measured PA(total) and self-reported leisure-time PA(discretionary time only) 1 week before vs. 1 week after the intervention; selected type and intensity of PA when placed in a gym setting for 30 min('cardio free choice'); screen time; self-efficacy toward PA; and intrinsic motivation toward exergaming.Results: Attendance at the exergaming sessions was high(80%). Compared with the control group, the intervention group self-reported an increase in PA(p = 0.035) and fewer hours watching television or videos(p = 0.01) after the intervention, but there were no significant differences in sedentary, light, moderate, or vigorous PA measured by accelerometry. The intervention group significantly improved self-efficacy toward PA(p = 0.028). The intervention group highly rated intrinsic motivation toward exergaming.Conclusion: Exergaming for 12 weeks was associated with positive impacts on adolescent girls' self-reported PA, television viewing, self-efficacy,and intrinsic motivation. Future research is warranted to leverage exergames as an enjoyable, motivating, and effective PA tool. | Amanda E.Staiano Robbie A.Beyl Daniel S.Hsia Peter T.Katzmarzyk Robert L.Newton Jr | 2017 | Journal of Sport and Health Science2017,6,1: | 9 |
| 7 | Current Status and Future Challenges of Weather Radar Polarimetry: Bridging the Gap between Radar Meteorology/Hydrology/Engineering and Numerical Weather Prediction显示文摘After decades of research and development, the WSR-88 D(NEXRAD) network in the United States was upgraded with dual-polarization capability, providing polarimetric radar data(PRD) that have the potential to improve weather observations,quantification, forecasting, and warnings. The weather radar networks in China and other countries are also being upgraded with dual-polarization capability. Now, with radar polarimetry technology having matured, and PRD available both nationally and globally, it is important to understand the current status and future challenges and opportunities. The potential impact of PRD has been limited by their oftentimes subjective and empirical use. More importantly, the community has not begun to regularly derive from PRD the state parameters, such as water mixing ratios and number concentrations, used in numerical weather prediction(NWP) models.In this review, we summarize the current status of weather radar polarimetry, discuss the issues and limitations of PRD usage, and explore potential approaches to more efficiently use PRD for quantitative precipitation estimation and forecasting based on statistical retrieval with physical constraints where prior information is used and observation error is included. This approach aligns the observation-based retrievals favored by the radar meteorology community with the model-based analysis of the NWP community. We also examine the challenges and opportunities of polarimetric phased array radar research and development for future weather observation. | Guifu ZHANG Vivek N.MAHALE Bryan J.PUTNAM Youcun QI Qing CAO ANDrew D.BYRD Petar BUKOVCIC Dusan S.ZRNIC Jidong GAO Ming XUE Youngsun JUNG Heather D.REEVES Pamela L.HEINSELMAN AlexANDer RYZHKOV Robert D.PALMER Pengfei ZHANG Mark WEBER Greg M.MCFARQUHAR Berrien MOORE III Yan ZHANG Jian ZHANG J.VIVEKANANDAN Yasser AL-RASHID Richard L.ICE Daniel S.BERKOWITZ Chong-chi TONG Caleb FULTON Richard J.DOVIAK | 2019 | Advances in Atmospheric Sciences2019,36,6: | 9 |
| 8 | 气候变化背景下人工造雪技术提升对中国滑雪季节长度的影响显示文摘在全球气候变暖背景下,人工造雪是滑雪场经营者有效应对气候变化的重要措施。本文假定人工造雪适宜温度由现有的-5℃提升到-2℃,基于气象站点观测数据(1981—2010年)和IPCC AR5的RCPs未来情景数据,通过改进的SkiSim 2.0模型评估气候变化背景下人工造雪技术提升对中国滑雪季节长度的影响。研究表明:①在气候变化背景下,人工造雪技术提升将使得中国平均滑雪季节长度增加3%~12%,即使在2080s时期最高温室气体排放情景下(RCP 8.5),78%的滑雪场能拥有超过100 d的滑雪季节长度;②受气候变化影响越大的滑雪场(如华北、华东、华中),人工造雪技术提升使其滑雪季节长度增加越多;而人工造雪技术提升对受气候变化影响小的滑雪场(如东北、西北)作用有限;③地理环境条件是影响滑雪季节长度的根本因素,无论人工造雪技术是否提升,气候变化背景下中国100 d滑雪季节长度的地理分界线均为长白山—阴山—祁连山—天山。为适应及减缓气候变化的潜在影响,相关部门应致力于提升人工造雪技术,从供给侧保证中国滑雪旅游产业的可持续发展。 | 方琰 Daniel Scott Robert Steiger 吴必虎 蒋依依 | 2020 | 资源科学2020,42,6: | 9 |
| 9 | 三维超高场7T高分辨磁敏感加权像静脉造影(英文)显示文摘目的超高场磁共振具有高信噪比和独特的磁敏感对比,使其在无创性脑血管造影尤其是对小静脉的检测有明显优势。本文探讨如何在超高场磁共振7T优化和获取高质量的磁敏感加权像(SWI)静脉造影。方法选择10例正常志愿者作为研究对象,采集一系列7TSWI静脉造影数据并与3T结果作对比。选择参数TR=30~45ms,TE=13~26ms,带宽(BW)=80~140Hz/pixel,翻转角(FA)=10~25?;所有的数据用同样的图像后处理方式得到最小信号叠加投影(mIP)的SWI静脉造影像,并进行定量化分析。结果图像优化后,我们得到高分辨率的7T静脉造影图像。根据静脉血的T2*选择优化TE:16ms(7T),28ms(3T);FA:15?(3T和7T)。相对于3T,7TSWI图像有较高的信噪比和静脉与周围组织的对比度,并显示出更多的微小静脉。结论超高场SWI静脉造影对于显示微小静脉具有明显的优势。 | Yulin Ge Samuel Barnes Samantha Heller Daniel K.Sodickson Lin Tang E.Mark Haacke Jianping Dai Robert I.Grossman | 2010 | 磁共振成像2010,1,2: | 8 |
| 10 | Screening and Surveillance for the Early Detection of Colorectal Cancer and Adenomatous Polyps, 2008: A Joint Guideline From the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology显示文摘 | Bernard Levin David A. Lieberman Beth McFarland Kimberly S. Andrews Durado Brooks John Bond Chiranjeev Dash Francis M. Giardiello Seth Glick David Johnson C. Daniel Johnson Theodore R. Levin Perry J. Pickhardt Douglas K. Rex Robert A. Smith Alan Thorson S | 2008 | Gastroenterology2008,,5: | 8 |
| 11 | 经腹机器人辅助腹腔镜肾部分切除术治疗T2期肾肿瘤的国际多中心临床研究显示文摘目的通过国际多中心研究探讨临床T2期肾肿瘤行经腹机器人辅助腹腔镜肾部分切除术的安全性及有效性。方法回顾性分析2012年1月至2017年12月国际19家泌尿中心378例临床T2期肾肿瘤行经腹机器人肾部分切除术和经腹机器人根治性肾切除术患者的临床资料。根据手术方式不同,分为部分切除组和根治组。部分切除组159例,男118例,女41例;年龄(59.3±13.2)岁,体重指数(28.7±5.4) kg/m^2,术前GFR (77.3±22.1)ml/min;肿瘤位于左侧72例,右侧87例;肿瘤直径(83±16)mm;R.E.N.A.L.评分(8.6±2.2)分。根治组219例,男156例,女63例;年龄(62.0±12.9)岁,体重指数(28.7±6.1) kg/m^2,术前GFR (71.4±20.3)ml/min;肿瘤位于左侧112例,右侧105例,双侧2例;肿瘤直径(92±25)mm;R.E.N.A.L.评分(9.7±1.5)分。两组患者性别、体重指数、肿瘤位置的差异均无统计学意义(P〉0.05)。部分切除组患者年龄、肿瘤直径、R.E.N.A.L.评分均低于根治组(P〈0.05),术前GFR优于根治组(P=0.012)。比较两组围手术期资料、肿瘤病理类型、随访时间、复发时间及术后GFR等。结果378例手术均顺利完成。部分切除组手术时间中位值150 min(65-353 min),短于根治组[180 min(85-361 min),P〈0.001],术中出血量中位值150 ml(40-3 000 ml),多于根治组[100 ml (10-1 100 ml),P〈0.001]。术中并发症发生率部分切除组为5.7%(9/159),根治组为3.2%(7/219),两组差异无统计学意义(P=0.240)。部分切除组术后并发症发生率高于根治组[19.5%(31/159)与10.5%(23/219),P=0.014],但≥3级并发症发生率的差异无统计学意义[4.4%(7/159)与2.3%(5/219),P=0.246]。部分切除组无复发生存率高于根治组[91.4%(117/128)与81.9%(167/204),P=0.013]。部分切除组术后GFR降低值16.9 ml/min(10.4-84.7 ml/min)明显少于根治组29.0 ml/min(14.0-54.0 ml/min),肾部分切除术更利于术后肾功能的保护(P〈0.001)。结论临床T2期肾肿瘤行机器人肾部分切除术可获得有效的肿瘤控制率,同时可以更好地保护肾功能,可作为临床T2期肾肿瘤有效的手术方式。 | 过菲 张超 王富博 王林辉 杨庆 叶华茂 吕晨 肖成武 汪洋 Giuseppe Simone Ithaar Derweesh Andrea Minervini Daniel Eun Francesco Porpiglia Sisto Perdona James Porter Matteo Ferro Alexandre Mottrie Robert Uzzo Luigi Schips Wesley White Ken Jacobsohn Prokar Dasgupta Riccardo Autorino Clayton Lau Chandru Sundaram Umberto Capitanio 孙颖浩 杨波 | 2018 | 中华泌尿外科杂志2018,39,6: | 8 |
| 12 | Gastroenteropancreatic neuroendocrine tumours显示文摘 | Irvin M Modlin Kjell Oberg Daniel C Chung Robert T Jensen Wouter W de Herder Rajesh V Thakker Martyn Caplin Gianfranco Delle Fave Greg A Kaltsas Eric P Krenning Steven F Moss Ola Nilsson Guido Rindi Ramon Salazar Philippe Ruszniewski Anders Sundin | 2008 | Lancet Oncology2008,,1: | 8 |
| 13 | Laparoscopic Colectomy for Cancer Is Not Inferior to Open Surgery Based on 5-Year Data From the COST Study Group Trial显示文摘 | James Fleshman Daniel J. Sargent Erin Green Mehran Anvari Steven J. Stryker Robert W. Beart Michael Hellinger Richard Flanagan Walter Peters Heidi Nelson | 2007 | Annals of Surgery2007,,4: | 7 |
| 14 | 强对流过程对大尺度模式洋面通量加强的参数化研究与进展显示文摘 | 张强 ZENG Xu-bin ROBERT E.Dickinson DANIEL E.Johnson TAO Wei-kuo | 2001 | 海洋学报2001,23,3: | 7 |
| 15 | Identification of four novel DC-SIGN ligands on Mycobacterium bovis BCG显示文摘Dendritic-cell-specific intercellular adhesion molecule-3-grabbing non-integrin(DC-SIGN;CD209)has an important role in mediating adherence of Mycobacteria species,including M.tuberculosis and M.bovis BCG to human dendritic cells and macrophages,in which these bacteria can survive intracellularly.DC-SIGN is a C-type lectin,and interactions with mycobacterial cells are believed to occur via mannosylated structures on the mycobacterial surface.Recent studies suggest more varied modes of binding to multiple mycobacterial ligands.Here we identify,by affinity chromatography and mass-spectrometry,four novel ligands of M.bovis BCG that bind to DC-SIGN.The novel ligands are chaperone protein DnaK,60 kDa chaperonin-1(Cpn60.1),glyceraldehyde-3 phosphate dehydrogenase(GAPDH)and lipoprotein lprG.Other published work strongly suggests that these are on the cell surface.Of these ligands,lprG appears to bind DC-SIGN via typical proteinglycan interactions,but DnaK and Cpn60.1 binding do not show evidence of carbohydrate-dependent interactions.LprG was also identified as a ligand for DC-SIGNR(L-SIGN;CD299)and the M.tuberculosis orthologue of lprG has been found previously to interact with human toll-like receptor 2.Collectively,these findings offer new targets for combating mycobacterial adhesion and within-host survival,and reinforce the role of DCSIGN as an important host ligand in mycobacterial infection. | Maria V.Carroll Robert B.Sim Fabiana Bigi Anne Jäkel Robin Antrobus Daniel A.Mitchell | 2010 | Protein & Cell2010,1,9: | 7 |
| 16 | Diagnosis and Management of the Metabolic Syndrome: An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement显示文摘 | Scott M. Grundy James I. Cleeman Stephen R. Daniels Karen A. Donato Robert H. Eckel Barry A. Franklin David J. Gordon Ronald M. Krauss Peter J. Savage Sidney C. Smith John A. Spertus Fernando Costa | 2005 | Circulation2005,,17: | 7 |
| 17 | Engineering the Smart Factory显示文摘The fourth industrial revolution promises to create what has been called the smart factory. The vision is that within such modular structured smart factories, cyber-physical systems monitor physical processes, create a virtual copy of the physical world and make decentralised decisions. This paper provides a view of this initiative from an automation systems perspective. In this context it considers how future automation systems might be effectively configured and supported through their lifecycles and how integration,application modelling, visualisation and reuse of such systems might be best achieved. The paper briefly describes limitations in current engineering methods, and new emerging approaches including the cyber physical systems(CPS) engineering tools being developed by the automation systems group(ASG) at Warwick Manufacturing Group, University of Warwick, UK. | HARRISON Robert VERA Daniel AHMAD Bilal | 2016 | Chinese Journal of Mechanical Engineering2016,29,6: | 7 |
| 18 | A tale of worldwide success:Behind the scenes of Carex(Cyperaceae)biogeography and diversification显示文摘The megadiverse genus Carex(c.2000 species,Cyperaceae)has a nearly cosmopolitan distribution,displaying an inverted latitudinal richness gradient with higher species diversity in cold-temperate areas of the Northern Hemisphere.Despite great expansion in our knowledge of the phylogenetic history of the genus and many molecular studies focusing on the biogeography of particular groups during the last few decades,a global analysis of Carex biogeography and diversification is still lacking.For this purpose,we built the hitherto most comprehensive Carex-dated phylogeny based on three markers(ETS-ITS-matK),using a previous phylogenomic Hyb-Seq framework,and a sampling of two-thirds of its species and all recognized sections.Ancestral area reconstaiction,biogeographic stochastic mapping,and diversification rate analyses were conducted to elucidate macroevolutionary biogeographic and diversification patterns.Our results reveal that Carex originated in the late Eocene in E Asia,where it probably remained until the synchronous diversification of its main subgeneric lineages during the late Oligocene.E Asia is supported as the cradle of Carex diversification,as well as a< | Santiago Martin-Bravo Pedro Jimenez-Mejias Tamara Villaverde Marcial Escudero Marlene Hahn Daniel Spalink Eric H.Roalson Andrew L.Hipp the Global Carex Group Carmen Benitez-Benitez Leo P.Bruederle Elisabeth Fitzek Bruce A.Ford Kerry A.Ford Mira Gamer Sebastian Gebauer Matthias H.Hoffmann Xiao-Feng Jin Isabel Larridon Etienne Ldveilld-Bourret Yi-Fei Lu Modesto Luceno Enrique Maguilla Jose Ignacio Marquez-Corro Monica Miguez Robert Naczi Anton A.Reznicek Julian R.Starr | 2019 | Journal of Systematics and Evolution2019,57,6: | 6 |
| 19 | IL-33, an Interleukin-1-like Cytokine that Signals via the IL-1 Receptor-Related Protein ST2 and Induces T Helper Type 2-Associated Cytokines显示文摘 | Jochen Schmitz Alexander Owyang Elizabeth Oldham Yaoli Song Erin Murphy Terril K. McClanahan Gerard Zurawski Mehrdad Moshrefi Jinzhong Qin Xiaoxia Li Daniel M. Gorman J. Fernando Bazan Robert A. Kastelein | 2005 | Immunity2005,,5: | 6 |
| 20 | The association of layperson characteristics with the quality of simulated cardiopulmonary resuscitation performance显示文摘BACKGROUND: Few studies have examined the association of layperson characteristics with cardiopulmonary resuscitation(CPR) provision. Previous studies suggested provider characteristics, including age and gender, were associated with CPR quality, particularly chest compression(CC) depth. We sought to determine the association of subject characteristics, including age and gender with layperson CPR quality during an unannounced simulated CPR event. We hypothesized shallower CC depth in females, and older-aged subjects.METHODS: As part of a larger multicenter randomized controlled trial of CPR training for cardiac patients' caregivers, CPR skills were assessed 6 months after training. We analyzed associations between subject characteristics and CC rate, CC depth and no-? ow time. Each variable was analyzed independently; signi? cant predictors determined via univariate analysis were assessed in a multivariate regression model.RESULTS: A total of 521 laypersons completed a 6-month CPR skills assessment and were included in the analysis. Mean age was 51.8±13.7 years, 75% were female, 57% were Caucasian. Overall, mean CC rate was 88.5±25.0 per minute, CC depth was 50.9±2.0 mm, and mean no-flow time was 15.9±2.7 sec/min. CC depth decreased signi? cantly in subjects >62 years(P<0.001). Male subjects performed deeper CCs than female subjects(47.5±1.7 vs. 41.9±0.6, P<0.001).CONCLUSION: We found that layperson age >62 years and female gender are associated with shallower CC depth. | Marion Leary David G.BucMer Daniel J.Ikeda Daiane A.Saraiva Robert A.Berg Vinay M.Nadkarni Audrey L.Blewer Benjamin S.Abella | 2017 | World Journal of Emergency Medicine2017,8,1: | 5 |