|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Prognostic value of pre-treatment F-18-FDG PET-CT in patients with hepatocellular carcinoma undergoing radioembolization显示文摘AIM To evaluate the value of pre-treatment 18F-FDG PET/CT in patients with HCC following liver radioembolization.METHODS We identified 34 patients with HCC who underwent an FDG PET/CT scan prior to hepatic radioembolization at our institution between 2009 and 2013. Patients wereseen in clinic one month after radioembolization and then at 2-3 mo intervals. We assessed the influence of FDG tumor uptake on outcomes including local liver control(LLC), distant liver control(DLC), time to distant metastases(DM), progression free survival(PFS) and overall survival(OS).RESULTS The majority of patients were males(n = 25, 74%), and had Child Pugh Class A(n = 31, 91%), with a median age of 68 years(46-84 years). FDG-avid disease was found in 19(56%) patients with SUVmax ranging from 3 to 20. Female patients were more likely to have an FDG-avid HCC(P = 0.02). Median follow up of patients following radioembolization was 12 months(1.2-62.8 mo). FDG-avid disease was associated with a decreased 1 year LLC, DLC, DM and PFS(P < 0.05). Using multivariate analysis, FDG avidity predicted for LLC, DLC, and PFS(all P < 0.05).CONCLUSION In this retrospective study, pre-treatment HCC FDGavidity was found to be associated with worse LLC, DLC, and PFS following radioembolization. Larger studies are needed to validate our initial findings to assess the role of F-18-FDG PET/CT scans as biomarker for patients with HCC following radioembolization. | Yazan Abuodeh Arash O Naghavi Kamran A Ahmed Puja S Venkat Youngchul Kim Bela Kis Junsung Choi Benjamin Biebel Jennifer Sweeney Daniel A Anaya Richard Kim Mokenge Malafa Jessica M Frakes Sarah E Hoffe Ghassan El-Haddad | 2016 | World Journal of Gastroenterology2016,22,47: | 3 |
| 2 | MinimaLLy invasive surgery for uroLogic disease in chiLdren显示文摘 | DanieLLe D Sweeney Marc C SmaLdone and Steven G Docimo | 2007 | NATURE CLINICAL PRACTICE2007,4,: | 1 |
| 3 | Multiple-system atrophy is genetically distinct from identified inherited causes of spinocerebellar degeneration 显示文摘 | Bandmann O Sweeney MG Daniel SE | 1997 | Neurology1997,49,6: | 1 |
| 4 | Gastric intestinal metaplasia development in African American predominant United States population显示文摘BACKGROUND Gastric cancer significantly contributes to cancer mortality globally.Gastric intestinal metaplasia(GIM)is a stage in the Correa cascade and a premalignant lesion of gastric cancer.The natural history of GIM formation and progression over time is not fully understood.Currently,there are no clear guidelines on GIM surveillance or management in the United States.AIM To investigate factors associated with GIM development over time in African American-predominant study population.METHODS This is a retrospective longitudinal study in a single tertiary hospital in Washington DC.We retrieved upper esophagogastroduodenoscopies(EGDs)with gastric biopsies from the pathology department database from January 2015 to December 2020.Patients included in the study had undergone two or more EGDswith gastric biopsy.Patients with no GIM at baseline were followed up until they developed GIM or until the last available EGD.Exclusion criteria consisted of patients age<18,pregnancy,previous diagnosis of gastric cancer,and missing data including pathology results or endoscopy reports.The study population was divided into two groups based on GIM status.Univariate and multivariate Cox regression was used to estimate the hazard induced by patient demographics,EGD findings,and Helicobacter pylori(H.pylori)status on the GIM status.RESULTS Of 2375 patients who had at least 1 EGD with gastric biopsy,579 patients were included in the study.138 patients developed GIM during the study follow-up period of 1087 d on average,compared to 857 d in patients without GIM(P=0.247).The average age of GIM group was 64 years compared to 56 years in the non-GIM group(P<0.001).In the GIM group,adding one year to the age increases the risk for GIM formation by 4%(P<0.001).Over time,African Americans,Hispanic,and other ethnicities/races had an increased risk of GIM compared to Caucasians with a hazard ratio(HR)of 2.12(1.16,3.87),2.79(1.09,7.13),and 3.19(1.5,6.76)respectively.No gender difference was observed between the study populations.Gastritis was associated with an increased risk for GIM development with an HR of 1.62(1.07,2.44).On the other hand,H.pylori infection did not increase the risk for GIM.CONCLUSION An increase in age and non-Caucasian race/ethnicity are associated with an increased risk of GIM formation.The effect of H.pylori on GIM is limited in low prevalence areas. | Akram I Ahmad Arielle Lee Claire Caplan Colin Wikholm Ioannis Pothoulakis Zaynab Almothafer NishthaRaval Samantha Marshall Ankit Mishra Nicole Hodgins In Guk Kang Raymond K Chang Zachary Dailey Arvin Daneshmand Anjani Kapadia Jae Hak Oh Brittney Rodriguez Abhinav Sehgal Matthew Sweeney Christopher B Swisher Daniel F Childers Corinne O'Connor Lynette M Sequeira Won Cho | 2022 | World Journal of Gastrointestinal Endoscopy2022,14,10: | 1 |
| 5 | Mitochondrial DNA polymorphisms in pathologically proven parkinson's disease显示文摘 | Bandmann O Sweeney MG Daniel SE | 1997 | J Neurol1997,244,4: | 1 |
| 6 | Nutrient losses in field-scale surface runoff from claypan soil receiving turkey litter and fertilizer显示文摘 | Daniel W. Sweeney Gary M. Pierzynski Phillip L. Barnes | 2012 | Agriculture Ecosystems and Environment2012,,: | 1 |
| 7 | Warfarin thromboprophylaxis in cancer patients with central venous catheters (WARP): an open-label randomised trial显示文摘 | Annie M Young Lucinda J Billingham Gulnaz Begum David J Kerr Ana I Hughes Daniel W Rea Stephen Shepherd Andrew Stanley Ann Sweeney Jonathan Wilde Keith Wheatley | 2009 | The Lancet . 2009 (9663)2009,,: | 1 |
| 8 | Minimally invasive surgery for urologic disease in children 显示文摘 | Danielle D Sweeney Mare C Smaldone Steven G Docimo | 2007 | Nature Clinical Practice2007,4,: | 1 |
| 9 | Too Frail for Surgery?: Initial Results of a Large Multidisciplinary Prospective Study Examining Pre-operative Variables Predictive of Poor Surgical Outcomes显示文摘 | Louis M. Revenig Daniel J. Canter Maxwell D. Taylor Caroline Tai John F. Sweeney Juan M. Sarmiento David A. Kooby Shishir K. Maithel Viraj A. Master Kenneth Ogan | 2013 | Journal of the American College of Surgeons2013,,: | 1 |
| 10 | Delivery Outcomes in Non-Tertiary Referral Centers for Women with Congenital Heart Disease显示文摘Background:Women with congenital heart disease(CHD)have increased risk for adverse events during pregnancy and delivery.Prior studies have assessed pregnancy and delivery outcomes at tertiary referral centers(TRC).The aim of our study was to assess pregnancy outcomes in women with CHD who deliver in a non-tertiary referral center(non-TRC).Methods:Clinical demographics were collected,including anatomic complexity,physiologic state and pre-pregnancy risk assessment.Patients were stratified by delivery location,either TRC or non-TRC.Maternal and neonatal complications of pregnancy were reported.Results:Women with CHD who delivered in a TRC had a higher pre-pregnancy risk when assessed by the Zahar and CARPREG-II scores,and had more patients fall into a higher WHO classification.There was no difference in rates of maternal cardiac complications between delivery locations(11%)and neonatal complications(20%)between deliveries at TRC and non-TRC.Conclusions:There were not increased maternal cardiac or neonatal complications when delivery occurred at a non-TRC.Neonatal complications remained high regardless of delivery location.This study suggests that proper risk assessment may help identify women who are candidates for safe delivery at non-TRC in women with CHD,and that neonatal resources should be considered when planning delivery location. | Daniel Sweeney Scott Cohen Salil Ginde Jennifer Gerardin Peter Bartz Matthew Buelow | 2023 | Congenital Heart Disease2023,18,3: | 0 |
| 11 | 高效检测谷物中的生物毒素——LC/MS/MS分析小麦中的单端孢霉烯毒素和玉米赤霉烯酮显示文摘本文介绍了采用改良型QuEChERS和Bond Elut Mycotoxin SPE样品处理方法并结合三重四级杆液质联用系统,检测谷物中的单端孢霉烯毒素和玉米赤霉烯酮,在降低分析成本的同时获得了极佳的检测灵敏度。 | Nick Byrd Danielle Sweeney Thomas Glauner | 2013 | 实验与分析2013,,2: | 0 |