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| 1 | The MRE11 GAR motif regulates DNA double-strand break processing and ATR activation显示文摘MRE11/RAD50/NBS1 建筑群是很快招募到 DNA 双海滨裂缝(DSB ) 的主要传感器。MRE11 被知道是由在它的 glycine-arginine-rich (长嘴硬鳞鱼) 以内的 PRMT1 的精氨酸 methylated 主题。在这研究,我们报导在 GAR 主题与离氨酸代替精氨酸并且产生 MRE11 缺乏 methylated 精氨酸的 RK 蛋白质。Mre11 RK/RK 老鼠对 γ 过分敏感;照耀(红外) 和从这些老鼠的房间显示了房间周期检查点缺点和染色体不稳定性。而且, Mre11 RK/RK MEF 展出了在 RPA 和 RAD51 的招募表明缺点和缺陷到损坏地点的 ATR/CHK1。M RK 形成的 RN 建筑群并且对 DNA 损坏并且通常的地点局部性响应红外激活 ATM 小径。M RK RN 建筑群在为响应红外在 vivo 观察的损害 DNA 结束切除术和 ATR 激活负责的 vitro 展出了 exonuclease 和 DNA 有约束力的缺点。我们的调查结果在 DSB 修理为 MRE11 长嘴硬鳞鱼主题的关键角色提供基因证据,并且在 MRE11 长嘴硬鳞鱼表明在 translational 以后修正之间的一个机械学的连接主题并且 DSB 处理,以及发信号的 ATR/CHK1 检查点。 | Zhenbao Yu Gillian Vogel Yan Coulombe Danielle Dubeau Elizabeth Spehalski Josee Hebert David O Ferguson Jean Yves Masson Stephane Richard | 2012 | Cell Research2012，22，2： | 5 |
| 2 | Mechanical characterisation of mullite-based ceramic matrix composites at test temperatures up to 1200°C显示文摘 | P.W.M. Peters B. Daniels F. Clemens W.D. Vogel | 2000 | Journal of the European Ceramic Society2000，，5： | 1 |
| 3 | Agrobacterium -mediated transformation and inbred line development in the model grass Brachypodium distachyon显示文摘 | John P. Vogel David F. Garvin Oymon M. Leong Daniel M. Hayden | 2006 | Plant Cell Tissue and Organ Culture2006，，2： | 1 |
| 4 | Cannabidiol effects on mRNA levels and signaling pathways in MOG-35–55 activated encephalitogenic T cells显示文摘 | Ewa Kozela Nathali Kaushansky Giovanni Coppola Daniel Geschwind Zvi Vogel Ana Juknat | 2014 | 2014 (1-2)2014，，1： | 1 |
| 5 | The nuclear genome of Brachypodium distachyon: analysis of BAC end sequences显示文摘 | Naxin Huo Gerard R. Lazo John P. Vogel Frank M. You Yaqin Ma Daniel M. Hayden Devin Coleman-Derr Theresa A. Hill Jan Dvorak Olin D. Anderson Ming-Cheng Luo Yong Q. Gu | | 0，2008，： | 1 |
| 6 | The nuclear genome of Brachypodium distachyon: analysis of BAC end sequences显示文摘 | Naxin Huo Gerard R. Lazo John P. Vogel Frank M. You Yaqin Ma Daniel M. Hayden Devin Coleman-Derr Theresa A. Hill Jan Dvorak Olin D. Anderson Ming-Cheng Luo Yong Q. Gu | 2008 | Functional & Integrative Genomics2008，，2： | 1 |
| 7 | EST sequencing and phylogenetic analysis of the model grass Brachypodium distachyon显示文摘 | John P. Vogel Yong Qiang Gu Paul Twigg Gerard R. Lazo Debbie Laudencia-Chingcuanco Daniel M. Hayden Teresa J. Donze Lindsay A. Vivian Boryana Stamova Devin Coleman-Derr | 2006 | Theoretical and Applied Genetics2006，，2： | 1 |
| 8 | Agrobacterium-mediated transformation and inbred line development in the model grass Brachypodium distachyon显示文摘 | John P. Vogel David F. Garvin Oymon M. Leong Daniel M. Hayden | 2006 | Plant Cell Tissue and Organ Culture2006，，2： | 1 |
| 9 | CHD5 Is a Tumor Suppressor at Human 1p36显示文摘 | Anindya Bagchi Cristian Papazoglu Ying Wu Daniel Capurso Michael Brodt Dailia Francis Markus Bredel Hannes Vogel Alea A. Mills | 2007 | Cell2007，，： | 1 |
| 10 | EST sequencing and phylogenetic analysis of the model grass Brachypodium distachyon显示文摘 | John P. Vogel Yong Qiang Gu Paul Twigg Gerard R. Lazo Debbie Laudencia-Chingcuanco Daniel M. Hayden Teresa J. Donze Lindsay A. Vivian Boryana Stamova Devin Coleman-Derr | | 0，2006，： | 1 |
| 11 | Tsc2 mutation induces renal tubular cell nonautonomous disease显示文摘TSC renal cystic disease is poorly understood and has no approved treatment.In a new principal cell-targeted murine model of Tsc cystic disease,the renal cystic epithelium is mostly composed of type A intercalated cells with an intact Tsc2 gene confirmed by sequencing,although these cells exhibit a Tsc-mutant disease phenotype.We used a newly derived targeted murine model in lineage tracing and extracellular vesicle(EV)characterization experiments and a cell culture model in EV characterization and cellular induction experiments to understand TSC cystogenesis.Using lineage tracing experiments,we found principal cells undergo clonal expansion but contribute very few cells to the cyst.We determined that cystic kidneys contain more interstitial EVs than noncystic kidneys,excrete fewer EVs in urine,and contain EVs in cyst fluid.Moreover,the loss of Tsc2 gene in EV-producing cells greatly changes the effect of EVs on renal tubular epithelium,such that the epithelium develops increased secretory and proliferative pathway activity.We demonstate that the mTORC1 pathway activity is independent form the EV production,and that the EV effects for a single cell line can vary significantly.TSC cystogenesis involves significant contribution from genetically intact cells conscripted to the mutant phenotype by mutant cell derived EVs. | Prashant Kumar Fahad Zadjali Ying Yao Daniel Johnson Brian Siroky Aristotelis Astrinidis Peter Vogel Kenneth W.Gross John J.Bissler | 2022 | Genes & Diseases2022，9，1： | 0 |
| 12 | Extracting structural motifs from pair distribution function data of nanostructures using explainable machine learning显示文摘Characterization of material structure with X-ray or neutron scattering using e.g.Pair Distribution Function(PDF)analysis most often rely on refining a structure model against an experimental dataset.However,identifying a suitable model is often a bottleneck.Recently,automated approaches have made it possible to test thousands of models for each dataset,but these methods are computationally expensive and analysing the output,i.e.extracting structural information from the resulting fits in a meaningful way,is challenging.Our Machine Learning based Motif Extractor(ML-MotEx)trains an ML algorithm on thousands of fits,and uses SHAP(SHapley Additive exPlanation)values to identify which model features are important for the fit quality.We use the method for 4 different chemical systems,including disordered nanomaterials and clusters.ML-MotEx opens for a type of modelling where each feature in a model is assigned an importance value for the fit quality based on explainable ML. | Andy S.Anker Emil T.S.Kjær Mikkel Juelsholt Troels Lindahl Christiansen Susanne Linn Skjærvø Mads Ry Vogel Jørgensen Innokenty Kantor Daniel Risskov Sørensen Simon J.L.Billinge Raghavendra Selvan Kirsten M.Ø.Jensen | 2022 | npj Computational Materials2022，，1： | 0 |
| 13 | LTE对下行链路干扰的敏感性显示文摘随着LTE被确立为主要的蜂窝标准,检测其脆弱性和可用性问题变得非常重要。研究人员开始通过研究干扰和干扰对网络通信的影响来揭示4G标准的敏感性。在这项工作中,软件LTE被部署在受控环境中,以针对商用现货(COTS)移动设备的通信进行各种可重现的干扰攻击。通过对每次攻击进行长期测量,收集了有关破坏通信所需干扰功率的统计数据。这些测量支持在实践中对理论上提出的攻击进行分析和评估。所获得的认知可用来评估现实世界中的干扰攻击对公共4G蜂窝网络的威胁。 | Daniel Vogel Daniel Rauschen Dennis Gl'asel 吴思韧(翻译) | 2021 | 通信对抗2021，40，1： | 0 |
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