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| 1 | Multimodality functional imaging using DW-MRI and 18F-FDG-PET/CT during radiation therapy for human papillomavirus negative head and neck squamous cell carcinoma: Meixoeiro Hospital of Vigo Experience显示文摘AIM To noninvasively investigate tumor cellularity measured using diffusion-weighted magnetic resonance imaging(DW-MRI) and glucose metabolism measured by 18 Flabeled fluorodeoxyglucose positron emission tomography/computed tomography(18F-FDG-PET/CT) during radiation therapy(RT) for human papillomavirus negative(HPV-) head and neck squamous cell carcinoma(HNSCC).METHODS In this prospective study, 6 HPV- HNSCC patients underwent a total of 34 multimodality imaging examinations(DW-MRI at 1.5 T Philips MRI scanner [(n = 24) pre-, during-(2-3 wk), and post-treatment(Tx), and 18F-FDG PET/CT pre- and post-Tx(n = 10)]. All patients received RT. Monoexponential modeling of the DW-MRI data yielded the imaging metric apparent diffusion coefficient(ADC) and the mean of standardized uptake value(SUV) was measured from 18F-FDG PET uptake. All patients had a clinical follow-up as the standard of care and survival status was documented at 1 year.RESULTS There was a strong negative correlation between the mean of pretreatment ADC(ρ =-0.67, P = 0.01) and the pretreatment 18F-FDG PET SUV. The percentage(%) change in delta(?) ADC for primary tumors and neck nodal metastases between pre- and Wk2-3 Tx were as follows: 75.4% and 61.6%, respectively, for the patient with no evidence of disease, 27.5% and 32.7%, respectively, for those patients who were alive with disease, and 26.9% and 7.31%, respectively, for those who were dead with disease.CONCLUSION These results are preliminary in nature and are indicative, and not definitive, trends rendered by the imaging metrics due to the small sample size of HPV- HNSCC patients in a Meixoeiro Hospital of Vigo Experience. | David Aramburu Núnez Antonio Lopez Medina Moisés Mera Iglesias Francisco Salvador Gomez Abhay Dave Vaios Hatzoglou Ramesh Paudyal Alfonso Calzado Joseph O Deasy Amita Shukla-Dave Victor M Munoz | 2017 | World Journal of Radiology2017，9，1： | 2 |
| 2 | Transgene and mitochondrial DNA are indicators of efficient composting of transgenic pig carcasses显示文摘 | Dave Murray Roy G. Meidinger Serguei P. Golovan John P. Phillips Ivan P. O’Halloran Ming Z. Fan Roger R. Hacker Cecil W. Forsberg | 2006 | Bioresource Technology2006，，9： | 1 |
| 3 | Splitting livers – balancing the gain and the pain显示文摘 | Dave Collett John O’Neill James Neuberger | 2007 | Transplant International2007，，3： | 1 |
| 4 | Volafilifies of different time resolutions--analyzing the dynamics of market components 显示文摘 | MULLER U DACOROGNA M DAVE R OLSEN R PICTET O WEIZSACKER J | 1997 | Journal of Empirical Finance1997，4，2： | 1 |
| 5 | Alterations in intestinal barrier function do not predispose to translocation of enteric bacteria in gastreenterologic patients 显示文摘 | O' Boyle CJ Mac Fie J Dave K | 1998 | Nutr Invest1998，14，4： | 1 |
| 6 | Sea Buckthom Products:Manufacture and Composition显示文摘 | Tom B Thomas S C L B Dave O | 1999 | J Agric Food Chem1999，47，： | 1 |
| 7 | Effect of deamidation and sue-einylation on solne Physieochemical and bakingPro Perties of gluten显示文摘 | Ma Chmg-Yung Dave O B John H | 1986 | Journal of Food science1986，51，1： | 1 |
| 8 | Volatilities of different time resolutions-analyzing the dynamics of market components显示文摘 | Müller U Dacorogna M Dave R Olsen R Pictet O Weizsacker J | 1997 | Journal of Empirical Finance1997，4，2： | 1 |
| 9 | The honey bee genome 显示文摘 | Lin Field Anthony James Dave O' Brochta | 2006 | Nature2006，314，： | 1 |
| 10 | Sea buckthorn products:manufacture and composition显示文摘 | TOM B THOMAS C L DAVE B O | 1999 | J Agric Food Chem1999，47，： | 1 |
| 11 | Queries and query processing in object-oriented database systems显示文摘 | DAVE D STRAUBE TAMER (O)ZSU M | 1990 | ACM Transaction on Information Systems1990，18，4： | 1 |
| 12 | The benefits of collaborative decision making in air traffic management显示文摘 | Hoffman R L Assessing Dave Knor | 2003 | IEEE2003，，： | 1 |
| 13 | Alterations in intestinal barrier function do not predispose to translocation of enteric bacteria in gastroenterologic patients显示文摘 | O'Boyle CJ Mac Fie J Dave K | 1998 | Nutritional Investigation1998，14，4： | 1 |
| 14 | Alterations in intestinal barrier function do not predispose to translocation of enteric bacteria in gastroenterologic patients显示文摘 | O'Boyle CJ MacFie J Dave K | 1998 | Nutrition1998，14，4： | 1 |
| 15 | Sea buckthom products:manufacture and composition 显示文摘 | Tom B Thomas S C L B Dave O | 1999 | Journal of Agricultural and Food Chemistry1999，47，9： | 1 |
| 16 | Variation in the composition of water-soluble polysaceharides in flaxseed 显示文摘 | DAVE B OOMAH E O KENASCHUK | 1995 | Journal of Agricultural and Food Chemistry1995，43，： | 1 |
| 17 | Alterations in in- testinal barrier function do not predispose to translocation of en- teric bacteria in gastroenterologic patients显示文摘 | O' BOYLE C J MAC FIE J DAVE K | 1998 | Nutr Invest1998，14，4： | 1 |
| 18 | Volatilities of different time resoulutions -- analyzing the dynamics of market components显示文摘 | Muller U Dacorogna M Dave R Olse R Pictet O Weizsacker J von | 1997 | Journal of Empirical Finance1997，4，： | 1 |
| 19 | Alterations in intesti- nal barrier function do not predispose to translocation of enteric bacteria in gastroenterologic patients显示文摘 | O' Boyle CJ MacFie J Dave K | 1998 | Nutri- tion1998，14，4： | 1 |
| 20 | Cyanobacterial vi bility during hydrothermal biomineralisation 显示文摘 | Phoenix Vernon R Adams Dave G Konhauser Kurt O | 2000 | Chemical Geology2000，169，： | 1 |
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