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7篇 您的检索式:作者名="David Lohse"
    题名 作者 年代 出处 被引量
1Unmet clinical need in autoimmune liver diseases显示文摘Jessica K. Dyson Gwilym Webb Gideon M. Hirschfield Ansgar Lohse Ulrich Beuers Keith Lindor David E.J. Jones 2014Journal of Hepatology2014,,:2
2人类对全球生态系统扰动的初步清查显示文摘本文将人类对自然生态系统的干扰按照程度的不同分成没有扰动、部分扰动和全被扰动三类,并采用这一分类体系进行制图。应用各种不同式样的图件做为原始资料,将其复制到一套覆盖全球的10张面积相等的底图上。这些图被数字化,并转换为地理信息系统以供分析。据此求得每个地区的表面积及其在三种扰动类型中的分配比例,还可推导出一个遗留下来的自然生境的指数。一个高的生境指数值表明一个区域全都是自然生境,人类的扰动很小。一个低的生境指数值表明一个区域受到了很大的扰动,几乎没有自然生境了。地球上尚有近9000万km^2的土地没有被扰动,约占地球陆地总面积52%。然而,地球上可居住部分,除了有岩石、冰的地方及荒地以外,近3/4都受到了某种方式的扰动。本文通过研究Udvardy8个生物地理带的扰动类型,对扰动的全球性模式的生物学意义进行了评价。本研究与早期的研究相比在方法上有所进步,包括绘图分辨率的提高、分类体系的扩大和对生境进行了生态学定义等。Lee Hannah Charles Hutchinson Johj L.Carr Ali Lankerani David Lohse 安逸 1994人类环境杂志1994,23,4:1
3Graft coplymer compatibilizers for blends of polypropylene and ethylene-propylene copolymers 显示文摘David J Lohse Sudhin Datta Edward N Kresge 1991Macromolecules1991,24,2:1
4Greater body mass index is associated with better pathologic features and improved outcome among patients treated surgically for clear cell renal cell carcinoma显示文摘Alexander S. Parker Christine M. Lohse John C. Cheville David D. Thiel Bradley C. Leibovich Michael L. Blute 2006Urology2006,,4:1
5TGF-β-dependent induction of CD4 + CD25 + Foxp3 + Tregs by liver sinusoidal endothelial cells显示文摘Antonella Carambia Barbara Freund Dorothee Schwinge Markus Heine Alena Laschtowitz Samuel Huber David C. Wraith Thomas Korn Christoph Schramm Ansgar W. Lohse Joerg Heeren Johannes Herkel 2014Journal of Hepatology2014,,3:1
6Relative Quantification of Long Chain Branching in Essentially Linear Polyethylenes 显示文摘Cesar A Garcia Franco David J Lohse Christopher G Robertson 2008European Polymer Journal2008,44,2:1
7MORTl/FADD is involved in liver regeneration显示文摘AIM: To explore the role of the adaptor molecule in liver regeneration after partial hepatectomy (PH). METHODS: We used transgenic mice expressing an N-terminal truncated form of MORT1/FADD under the control of the albumin promoter. As previously shown, this transgenic protein abrogated CD95- and CD120a-mediated apoptosis in the liver. Cyclin A expression was detected using Western blotting. ELISA and RT-PCR were used to detect IL-6 and IL-6 mRNA, respectively. DNA synthesis in liver tissue was measured by BrdU staining. RESULTS: Resection of 70% of the liver was followed by a reduced early regenerative response in the transgenic group at 36 h. Accordingly, 36 h after hepatectomy, cyclin A expression was only detectable in wild-type animals. Consequently, the onset of liver mass restoration was retarded as measured by MRI volumetry and mortality was significantly higher in the transgenic group. CONCLUSION: Our data demonstrate for the first time an involvement of the death receptor molecule MORT1/ FADD in liver regeneration, beyond its well described role as part of the intracellular death signaling pathway.Marcus Schuchmann Felix Rückert Jose F Garcia-Lazaro Andrea Karg Jürgen Burg Natalia Knorr Jürgen Siebler Eugene E Varfolomeev David Wallach Wolfgang Schreiber Ansgar W Lohse Peter R Galle 2005World Journal of Gastroenterology2005,11,46:0
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