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| 1 | Timely reperfusion for ST-segment elevation myocardial infarction:Effect of direct transfer to primary angioplasty on time delays and clinical outcomes显示文摘Primary percutaneous coronary intervention(PPCI) is the preferred reperfusion therapy for patients presenting with ST-segment elevation myocardial infarction(STEMI) when it can be performed expeditiously and by experienced operators. In spite of excellent clinical results this technique is associated with longer delays than thrombolysis and this fact may nullify the benefit of selecting this therapeutic option. Several strategies have been proposed to decrease the temporal delays to deliver PPCI. Among them,prehospital diagnosis and direct transfer to the cath lab,by-passing the emergency department of hospitals,has emerged as anattractive way of diminishing delays. The purpose of this review is to address the effect of direct transfer on time delays and clinical events of patients with STEMI treated by PPCI. | Rodrigo Estévez-Loureiro ángela López-Sainz Armo Pérez de Prado Carlos Cuellas Ramón Calvio Santos Norberto Alonso-Orcajo Jorge Salgado Fernández Jose Manuel Vázquez-Rodríguez Maria López-Benito Felipe Fernández-Vázquez | 2014 | World Journal of Cardiology2014，6，6： | 6 |
| 2 | Short and long term fate of human AMSC subcutaneously injected in mice显示文摘AIM:To study the ability of human adipose-derived mesenchymal stem cells(AMSCs)to survive over the short and long term,their biodistribution and their biosafety in vivo in tumor-prone environments.METHODS:We subcutaneously injected human AMSCs from different human donors into immunodeficient SCID mice over both short-(2 and 4 mo)and long-(17 mo)term in young,and aged tumor-prone mice.Presence of human cells was studied by immunohistochemistry and polymerase chain reaction analysis in all organs of injected mice.RESULTS:Subcutaneously injected AMSCs did not form teratomas at any time point.They did not migrate but remained at the site of injection regardless of animal age,and did not fuse with host cells in any organ examined.AMSCs survived in vivo for at least 17 mo after injection,and differentiated into fibroblasts of the subdermic connective tissue and into mature adipocytes of fat tissue,exclusively at the site of injection.CONCLUSION:Our results support the assertion that AMSC may be safe candidates for therapy when injected subcutaneously because of their long term inability to form teratomas. | Pilar López-Iglesias Alejandro Blázquez-Martínez Jorge Fernández-Delgado Javier Regadera Manuel Nistal Maria P De Miguel | 2011 | World Journal of Stem Cells2011，3，6： | 5 |
| 3 | Diagnostic yield and clinical outcomes after capsule endoscopy in 100 consecutive patients with obscure gastrointestinal bleeding显示文摘 | Emilio Estévez Benito González-Conde José Luis Vázquez-Iglesias Maria de los Angeles Vázquez-Millán Sonia Pértega Pedro A. Alonso Joan Clofent Eva Santos José Luis Ulla Eloy Sánchez | 2006 | European Journal of Gastroenterology & Hepatology2006，，8： | 3 |
| 4 | Effect of rapamycin on hepatic osteodystrophy in rats with portasystemic shunting显示文摘瞄准:如果与推延的 portasystemic 有关的 T 房间激活通过 RANKL 依赖的小径引起调停骨破折的骨头损失,学习。如果用 rapamycin 的 T 房间抑制将在老鼠免于骨头损失,我们也调查了。方法:推延的 Portasystemic 在男 Sprague-Dawley 老鼠和 rapamycin 被执行 0.1 mg/kg 被管饲法为 15 wk 管理。老鼠收到了 powderized 食物并且补加喂在骨头作文上阻止营养不良的效果。重量获得和生长在推延的动物在外科以后被恢复。在结束,骨头周转和量的骨头组织学的生物化学的参数被估计。T 房间激活,煽动性的 cytokine 生产,和 RANKL 依赖的小径的标记被测量。另外, IGF-1 和性腺机能减退的角色被调查。结果:推延的 Portasystemic 引起了是 RANKL 独立人士的低周转骨质疏松症。包括 IL-1, IL-6 和 TNFalpha,骨头再吞 cytokine 层次没在浆液和 TNFalpha 被增加, RANKL 表示不起来在 PBMC 调整了。推延的 Portasystemic 增加了传播 CD8+T 房间人口。Rapamycin 减少了传播 CD8+T 房间人口,增加了 CD8+CD25+T 规章的房间人口并且改进了骨头周转的所有参数。结论:推延的 portasystemic 引起的骨质疏松症可以被 rapamycin 部分在肝的骨营养不良的老鼠模型改善。 | Schalk W van der Merwe Maria M Conradie Robert Bond Brenda J Olivier Elongo Fritz Martin Nieuwoudt Rhena Delport Tomas Slavik Gert Engelbrecht Del Kahn Enid G Shephard Maritha J Kotze Nico P de Villiers Stephen Hough | 2006 | World Journal of Gastroenterology2006，12，28： | 2 |
| 5 | Environmental risk factors in inflammatory bowel diseases. Investigating the hygiene hypothesis: A Spanish case–control study显示文摘 | Pilar López-Serrano José L. Pérez-Calle Maria Teresa Pérez-Fernández Juan Manuel Fernández-Font Daniel Boixeda de Miguel Conrado M. Fernández-Rodríguez | 2010 | Scandinavian Journal of Gastroenterology2010，，12： | 1 |
| 6 | Silica-immobilized piperazine:A sustainable organocatalyst for aldo/and knoevenage] reactions显示文摘 | SHANMUGANATHAN S GREINER L DE MARIA P D | 2010 | Tetrahedron Letters2010，51，50： | 1 |
| 7 | Dietary antioxidants:im- munity and host defense 显示文摘 | Maria A P Elena P Gerardo A de C | 2011 | Current Topics in Medicinal Chemistry2011，11，14： | 1 |
| 8 | Chemical modification of cross-linked resinbased on acrylonitrile for anchoring metal ions 显示文摘 | de Santa Maria L C Amorim M C V Aguiar M R M P | 2001 | Reactive and Functional Polymers2001，49，2： | 1 |
| 9 | Biotechnological applications of Candida antarctica lipase A: state-of-the-art显示文摘 | DE MARIA P D CARBONI-OERLEMANS C TUIN B | 2005 | Journal of molecular catalysis B: Enzymatic2005，37，16： | 1 |
| 10 | An artificial skin based on optoelectronic technology显示文摘 | Cirillo A Cirillo P de Maria G | 2014 | Sensors and Actuators A: Physical2014，212，： | 1 |
| 11 | Ionic liquids in biotransformations: from proof-of-concept to emerging deep-euteetic-solvents显示文摘 | de Maria P D Mauger Z | 2011 | Curt Opin Chem Biol2011，15，： | 1 |
| 12 | Lipase-catalyzed (trans)esterification of 5-hydroxymethyl furfural and separation from HMF esters using deep-eutectic solvents 显示文摘 | Krystof M Perez-Sanchez M de Maria P D | 2013 | ChemSusChem2013，6，： | 1 |
| 13 | Antioxidant Acton of Bixin Against CisplatinInduced Chromosome Aberrations and Lipid Peroxidation in Rats显示文摘 | Cec(I)lia Rodrigues Siva Lus(a)nua M Greggu Abtyes abd Maria De Lourdes P | 2001 | Pharmacological Research2001，43，6： | 1 |
| 14 | Oral doxophylline in patients withchronic obstructive pulmonary disease显示文摘 | Viillani F De Maria P Ronchi E | 1997 | Int J Clin Pharmacol Ther Toxicol1997，35，3： | 1 |
| 15 | Primary non--Hodgkin's lymphoma of the mandible, report of a case 显示文摘 | Longo F De Maria G Esposito P | 2004 | Int J Oral Maxillofac Surg2004，33，8： | 1 |
| 16 | Cancer stem cells and chemosensitivity显示文摘 | Maugeri-Saccà M Vigneri P De Maria R | | 0，，： | 1 |
| 17 | Cancer stem cell defini- tions and terminology : the devil is in the details 显示文摘 | Valent P Bonnet D De Maria R | 2012 | Nat Rev Cancer2012，12，11： | 1 |
| 18 | Evaluation of the association between osteoporosis and postural balance in postmenopausal women显示文摘 | Guilherme Carlos Brech Pérola Grinberg Plapler Eduardo de Souza Meirelles Flora Maria D’Andrea Marcolino Júlia Maria D’Andrea Greve | 2013 | Gait & Posture2013，，2： | 1 |
| 19 | How does coronary stent implantation impact on the status of the microcirculation during primary percutaneous coronary intervention in patients with ST-elevation myocardial infarction?显示文摘 | De Maria Giovanni Luigi Cuculi Florim Patel Niket Dawkins Sam Fahrni Gregor Kassimis George Choudhury Robin P. Forfar John C. Prendergast Bernard D. Channon Keith M. Kharbanda Rajesh K. Banning Adrian P | 2015 | European Heart Journal2015，，： | 1 |
| 20 | Survivin gene-expression andsplicing isoforms in oral squamous cell carcinoma显示文摘 | De Maria S Pannone G Bufo P | 2009 | J Cancer ResClin Oncol2009，135，1： | 1 |
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