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| 1 | 前蛋白转化酶枯草杆菌蛋白酶kexin-9在肾病综合征相关性高胆固醇血症中的作用显示文摘肾病综合征中,肾脏足细胞损害可导致严重的高胆固醇血症,迫切需要新的治疗方法。前蛋白转化酶枯草杆菌蛋白酶kexin-9(proprotein convertase subtilisin/kexin type 9,PCSK9)逐渐成为血浆总胆固醇水平和治疗目标的重要调节因子。 | 刘莉 叶鹏 Haas ME Levenson AE Sun X Liao WH Rutkowski JM de Ferranti SD Schumacher VA Scherer PE Salant DJ Biddinger SB | 2016 | 中华高血压杂志2016，24，7： | 3 |
| 2 | Matrilin-2, an extracellular adaptor protein, is needed for the regeneration of muscle, nerve and other tissues显示文摘The extracellular matrix(ECM) performs essential functions in the differentiation, maintenance and remodeling of tissues during development and regeneration, and it undergoes dynamic changes during remodeling concomitant to alterations in the cell-ECM interactions. Here we discuss recent data addressing the critical role of the widely expressed ECM protein, matrilin-2(Matn2) in the timely onset of differentiation and regeneration processes in myogenic, neural and other tissues and in tumorigenesis. As a multiadhesion adaptor protein, it interacts with other ECM proteins and integrins. Matn2 promotes neurite outgrowth, Schwann cell migration, neuromuscular junction formation, skeletal muscle and liver regeneration and skin wound healing. Matn2 deposition by myoblasts is crucial for the timely induction of the global switch toward terminal myogenic differentiation during muscle regeneration by affecting transforming growth factor beta/bone morphogenetic protein 7/Smad and other signal transduction pathways. Depending on the type of tissue and the pathomechanism, Matn2 can also promote or suppress tumor growth. | éva Korpos Ferenc Deák Ibolya Kiss | 2015 | Neural Regeneration Research2015，10，6： | 2 |
| 3 | Direct Composite Coronal Reconstructionof Two Fractured Incisors:an 8-year Follow-up显示文摘 | De La Pefia VA Cabrita OB | 2005 | Dent Traumatol2005，21，5： | 1 |
| 4 | Chemotherapy for primany lymphoma of the central nervous system显示文摘 | Levin VA | 1990 | Neurology1990，40，1： | 1 |
| 5 | Molecular ecology and pathogenic potential of Fonsecaea species显示文摘 | De Hoog GS Attili-Angelis D Vicente VA | | 0，，5： | 1 |
| 6 | TheWnt/frizzled/GSK-3p pathway : a novel therapeutic target forcardiac hypertrophy 显示文摘 | Blankesteijn WM van de Schans VA ter Horst P | 2008 | Trends Pharmacol Sci2008，29，4： | 1 |
| 7 | Interruption of Wnt signaling attenuates the onset of pressureoverload-induced cardiac hypertrophy 显示文摘 | van de Schans VA van den Borne SW Strzelecka AE | 2007 | Hypertension2007，49，3： | 1 |
| 8 | Associations between pro-moter usage and alternative splicing of the glucocorticoid receptorgene显示文摘 | Russcher H Dalm VA de Jong FH | 2007 | J Mol Endocrinol2007，38，： | 1 |
| 9 | Cephalometric evaluation of pharyngeal airway space changes in class 111 patients undergoing orthognathic surgery 显示文摘 | Pereira-Filho VA Castro-Silva LM de Moraes M | 2011 | J Oral Maxillofac Surg2011，69，11： | 1 |
| 10 | Thymsin alpha 1 : a novel therapeutic optian for patients with refracto- ry chronic putlent rhinosinusitis显示文摘 | Dalm VA de Wit H Drexhage HA | 2012 | Ann NY Acad SCI2012，1270，： | 1 |
| 11 | Postoperative ambulation: back to basics 显示文摘 | Kibber VA Hayes RM Johnson DE | 2012 | Am J Nurs2012，11，4： | 1 |
| 12 | Comparison of the results of human embryo biopsy and outcome of PGD after zona drilling using acid Tyrode medium or a laser显示文摘 | Joris H De VA Janssens R | 2003 | Hum Reprod2003，18，9： | 1 |
| 13 | Three2dimensional phase contrast MR cerebral venogaphy with zero filling interpolation in the slice encoding direction 显示文摘 | Loubeyree P De Jaehere T Tran2Minh VA | 1999 | Magn Reson Imaging1999，117，8： | 1 |
| 14 | Neuromyelitis optica and non-organ-specific autoimmunity 显示文摘 | Pittock S J Lennon VA de Seze J | 2008 | Arch Neurol2008，65，1： | 1 |
| 15 | The Wnt/frizzled/GSK-313 pathway: a novel therapeutic target for cardiac hypertrophy 显示文摘 | Blankesteijn WM van de Schans VA ter Horst P | 2008 | Trends Pharmacol Sci2008，29，4： | 1 |
| 16 | An antiprolifcrative BMP-2/PPARgamma/apoE axis in human and murine SMCs and its role in pulmonary hypertension 显示文摘 | Hansmann G de Jesus Perez VA Alastalo TP et at | 2008 | J Clin Invest2008，118，： | 1 |
| 17 | Pet therapy in elderly patients with mental illness显示文摘 | Moretti F De Roncbi D Bernabei VA | 2011 | Psychogeriat- tics2011，11，2： | 1 |
| 18 | The clinical relevanc of the ro-tational deformity after femoral shaft fracture treated with intramedullary nailing 显示文摘 | Liebrand H ridderde VA lang DE | 2002 | Osteo Frauma Care2002，10，2： | 1 |
| 19 | Reduced survival after human embryo and subsequent cryopreservation显示文摘 | Joris H Van den AE De VA | 1999 | Hum Reprod1999，14，11： | 1 |
| 20 | Obesity and dental caries among preschool children in Brazil显示文摘 | Granville-Garcia AF de Menezes VA de Lira PI | 2008 | Rev Salud Publiea(Bogota)2008，10，5： | 1 |
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