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| 1 | Second-look surgery plus hyperthermic intraperitoneal chemotherapy for patients with colorectal cancer at high risk of peritoneal carcinomatosis:Does it really save lives?显示文摘The treatment of peritoneal carcinomatosis (PC) of colorectal origin with cytoreductive surgery(CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) has a 5-year recurrence-free or cure rate of at least 16%, so it is no longer labeled as a fatal disease, and offers prolonged survival for patients with a low peritoneal carcinomatosis index. Metachronous PC of colorectal origin is so predictable that there is a model which has been used to successfully determine the individual risk of each patient. Patients at risk are clearly identified; those with the highest risk have small peritoneal nodules present in the first surgery (70% probability of developing PC), ovarian metastases(60%), perforated tumor onset or intraoperative tumor rupture(50%). Current clinical, biological and imaging techniques still lack sufficient sensitivity to diagnose PC in its initial stages, when CRS plus HIPEC has a greater impact and a higher cure rate. Second-look surgery with HIPEC or prophylactic HIPEC at the time of the first intervention have been proposed as means of preventing and/or anticipating clinical or radiological relapse in at-risk patients. Both techniques have shown a significant decrease in peritoneal relapses and should be considered essential weapons in the management of colorectal cancer. | Delia Cortes-Guiral Dominique Elias Pedro Antonio Cascales-Campos Alfredo Badía Yébenes Ismael Guijo Castellano Ana Isabel León Carbonero JoséIgnacio Martín Valadés Jesus Garcia-Foncillas Damian Garcia-Olmo | 2017 | World Journal of Gastroenterology2017，23，3： | 3 |
| 2 | Gastric emptying effect by 4-aminopyridine in patients with chronic spinal cord injury显示文摘 | Israel Grijalva Gabriel Guízar-Sahagún Delia RodríguezPacheco | | 0，，04： | 1 |
| 3 | Conservation across species identifies several transcriptional enhancers in the HEX genomic region显示文摘 | Delia AV Bregant E Passon N | 2009 | Mol Cell Biochem2009，332，1： | 1 |
| 4 | The impact of common and rare EGFR mutations in response to EGFR tyrosine kinase inhibitors and platinum-based chemotherapy in patients with non-small cell lung cancer显示文摘 | Oscar Arrieta Andrés Felipe Cardona Luis Corrales Alma Delia Campos-Parra Roberto Sánchez-Reyes Eduardo Amieva-Rivera July Rodríguez Carlos Vargas Hernán Carranza Jorge Otero Nikki Karachaliou Horacio Astudillo Rafael Rosell | 2014 | Lung Cancer2014，，： | 1 |
| 5 | Screening and HPLC methods for carotenoids in sweet potato,cassava and maize for plant breeding trials显示文摘 | Kimura M Cintia N Delia B | 2007 | Food Chemistry2007，100，： | 1 |
| 6 | Microbial deeolorization of reactive azo dyes in a sequential anaerobic-aerobic system 显示文摘 | Supaka N Juntongjin K Damronglerd S Delia M L Strehaiano P | 2004 | Chemical Engineering Journal2004，99，2： | 1 |
| 7 | Impact of leachate recirculation and recirculation volume on stabilization of municipal solid wastes in simulated anaerobic bioreactors显示文摘 | Delia T S Osman N A | 2004 | Process Biochemistry2004，39，2： | 1 |
| 8 | Corneal astigmatism induced by superior versus temporal corneal incisions for extracapsular cataract extraction 显示文摘 | Wong HC Davis G Delia N | 2009 | Clinical & Experimental Ophthalmology2009，22，4： | 1 |
| 9 | Induced defenses of Veronica spicata : Variability in herbivore-induced volatile organic compounds显示文摘 | Delia M. Pinto-Zevallos Heidi Hellén Hannele Hakola Saskya van Nouhuys Jarmo K. Holopainen | 2013 | Phytochemistry Letters2013，，4： | 1 |
| 10 | Corneal astigmatism induced by superior Versus temporal corneal incisions for extracapsular cataract extraction显示文摘 | Wang HC Davis G Delia N | 1994 | Aust N Z J Ophthalmol1994，22，4： | 1 |
| 11 | Anaerobic/aerobic treatment of municipal tandfill leachate in sequential two-stage up-flow anaerobic sludge blanket reactor (UASB)/completely stirred tank reactor (CSTR) systems显示文摘 | AGDAG O N DELIA T S | 2005 | Process Biochemistry2005，40，2： | 1 |
| 12 | Conservation across species identifies several transcript-tional enhancers in the HEX genomic region显示文摘 | DElia A V Bregant E Passon N | 2009 | Mol Cell Biochem2009，332，1： | 1 |
| 13 | Use of a barbed suture in the closure of hip and knee arthroplasty wounds 显示文摘 | Levine BR Ting N Delia Valle CJ | 2011 | Orthopedics2011，34，9： | 1 |
| 14 | Increased plasma levels of soluble CD40, together with the decrease of TGFbetal, as possible differential markers of Alzheimer disease 显示文摘 | Mocali A Cedrola S Delia Malva N | 2004 | Exp Gerontol2004，39，10： | 1 |
| 15 | Impact of leachate recirculation and recirculation volume on stabilization of municipal solidwastes in simulated anaerobic bioreactors显示文摘 | Delia T S Osman N A | 2004 | Process Biochemistry2004，39，12： | 1 |
| 16 | Characterization of Tako-tsubo Cardiomyopathy in Spain: Results from the RETAKO National Registry显示文摘 | Iván J. Nú?ez Gil Mireia Andrés Manuel Almendro Delia Alessandro Sionis Ana Martín Teresa Bastante Juan Gabriel Córdoba Soriano José A. Linares Vicente Silvia González Sucarrats Alejandro Sánchez-Grande Flecha | 2014 | Revista Espa?ola de Cardiología (English Edition)2014，，： | 1 |
| 17 | Homogeneous Microscopic Abnormalities in Sperm Morphology and Immotility as A Cause of Male Infertility显示文摘Objective To study the identification of the cause of specific sperm abnormalities.Methods Two adult men with specific alterations in sperm morphology causing 100%immobility were included in this study. The study of sperm used: transmission electron microscopy(both patients); apoptotic markers, DNA fragmentation test and fluorescence in-situ hybridization(patient 1) and immunocytochemistry study of sperm flagellum using anti-β tubulin antibodies and ciliary activity test(patient 2).Results Increased DNA fragmentation(52.6%) and apoptosis biomarkers were detected in patient 1, and loss of the central pair of microtubules in patient 2(‘9+0'axoneme); the nasal ciliary activity was normal.Conclusion Results suggest an apoptotic origin of the abnormalities in the sperm from patient 1 and dysplasia of the fibrous sheath in patient 2. | Delia Acevedo León Josep Ventura Gayete Carmen Aguado Mu?oz Carmen Carda Batalla Miguel Armengot Carceller Jerónimo Forteza Vila | 2014 | Journal of Reproduction and Contraception2014，25，2： | 0 |
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