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| 1 | Inactivation efficiency of slightly acidic electrolyzed water against microbes on facility surfaces in a disinfection channel显示文摘Slightly acidic electrolyzed water(SAEW,pH 6.0-6.5)is an ideal and environmentally-friendly disinfectant,which was used to prevent and control bacterial infections on farms.This work aims to investigate the inactivation effectiveness of SAEW in inactivating microbes in a disinfection channel.The bactericidal efficiency of SAEW on equipment surfaces was compared to two commercial disinfectants,Kuei A bromide solution(KAS,5:1000 v/v)and Glutaraldehyde solution(GS,5:1000 v/v).The disinfection effectiveness of SAEW in inactivating Salmonella enteritidis(S.enteritidis)on equipment surfaces in the disinfection channel was evaluated,and a model was developed using multiple linear regression analysis.Results indicated that SAEW was significantly(p<0.05)more efficient than KAS and GS on kits and clothing in the disinfection channel at 1 min.The SAEW did not contribute as aggressively to respiratory difficulty as KAS and GS.Maximum reductions of 2.362 log10 CFU/cm^(2),2.613 log10 CFU/cm^(2) and 2.359 log10 CFU/cm^(2) for Salmonella enteritidis were obtained from clothing surfaces,iron materials,and kits treated with SAEW for 2.5 min at a chlorine concentration of 220 mg/L.Moreover,the established model had a good fit-quantified by the determination coefficient R^(2)(0.939)and a lack of fit test(p>0.05).In addition,available chlorine concentration(ACC)was an important factor than other factors,and the inactivation efficiency of Salmonella enteritidis sprayed by SAEW treatment was different between iron materials,kits and clothing surfaces(iron>kit>clothing). | Zang Yitian Li Baoming Shi Zhengxiang Sheng Xiaowei Wu Hongxiang Shu Dengqun | 2017 | International Journal of Agricultural and Biological Engineering2017，10，6： | 2 |
| 2 | Do patients with pN0 gastric cancer benefit from prophylactic extended lymphadenectomy?显示文摘 | Dengqun Sun Renhua Gong Haorong Wu | 2011 | Surgical Oncology2011，，1： | 1 |
| 3 | Temporal transcriptomics reveal the molecular mechanism of dormancy and germination regulated by temperature in Paris polyphylla seed显示文摘The mature seed of Paris polyphylla var.chinensis(PPC)is morphophysiologically dormant and develops differently under warm and cold temperatures.To elucidate the molecular mechanisms underlying temperature-dependent regulation of PPC seed dormancy and germination,we investigated the dynamic changes in PPC seed transcript levels under warm and cold temperature stratifications(WS and CS,respectively)by time-resolved RNA sequencing,focusing on genes related to hormone metabolism and signaling and cell wall remodeling(CWRM)and encoding transcription factors/regulators(TFs/TRs).A total of 48765 and 47836 differentially expressed genes(DEGs)were associated with WS and CS,respectively.Of these,17581 and 16652 DEGs,respectively,unique to WS and CS,and 5386 were common to both temperature stratifications across nine analyzed growth stages.The expression of hormone metabolism and signaling,TF/TR,and CWRM genes were closely associated with temperature.More genes related to gibberellin(GA),cytokinin,auxin,and brassinosteroid biosynthetic were upregulated in WS as compared to CS seeds,while genes related to dormancy release and germination were downregulated in WS seeds.However,only GA and abscisic acid levels were altered in PPC seeds breaking morphophysiological dormancy(MPD).Overall,37 TF and five TR families were upregulated whereas 24 TF and 16 TR families were downregulated in WS as compared to CS seeds.Most CWRM families were highly expressed under WS as compared to CS,suggesting that they promote endosperm weakening and embryo growth of WS seeds and facilitate MPD release and germination.A coexpression analysis revealed positive correlations between TFs/TRs and DEGs involved in hormone metabolism and signaling and CWRM.These results provided a basis for investigating the interaction between the endosperm and underdeveloped embryo in the regulation of PPC seed germination and seedling emergence. | Dengqun Liao Yalan Chen Jianjun Qi Hongliang Zhang Peng Sun Caixia Chen Xian'en Li | 2023 | Horticultural Plant Journal2023，9，4： | 1 |
| 4 | The role of TRPP2 in agonist-induced gallbladder smooth muscle contraction显示文摘TRPP2 channel protein belongs to the superfamily of transient receptor potential(TRP) channels and is widely expressed in various tissues, including smooth muscle in digestive gut. Accumulating evidence has demonstrated that TRPP2 can mediate Ca^(2+) release from Ca^(2+) stores. However, the functional role of TRPP2 in gallbladder smooth muscle contraction still remains unclear. In this study, we used Ca^(2+) imaging and tension measurements to test agonist-induced intracellular Ca^(2+) concentration increase and smooth muscle contraction of guinea pig gallbladder, respectively. When TRPP2 protein was knocked down in gallbladder muscle strips from guinea pig, carbachol(CCh)-evoked Ca^(2+) release and extracellular Ca^(2+) influx were reduced significantly, and gallbladder contractions induced by endothelin 1 and cholecystokinin were suppressed markedly as well. CCh-induced gallbladder contraction was markedly suppressed by pretreatment with U73122, which inhibits phospholipase C to terminate inositol 1,4,5-trisphosphate receptor(IP3) production, and 2-aminoethoxydiphenyl borate(2APB), which inhibits IP3 recepor(IP3R) to abolish IP3R-mediated Ca^(2+) release. To confirm the role of Ca^(2+) release in CCh-induced gallbladder contraction, we used thapsigargin(TG)-to deplete Ca^(2+) stores via inhibiting sarco/endoplasmic reticulum Ca^(2+)-ATPase and eliminate the role of store-operated Ca^(2+) entry on the CCh-induced gallbladder contraction. Preincubation with 2 μmol L^(-1) TG significantly decreased the CCh-induced gallbladder contraction. In addition, pretreatments with U73122, 2APB or TG abolished the difference of the CCh-induced gallbladder contraction between TRPP2 knockdown and control groups. We conclude that TRPP2 mediates Ca^(2+) release from intracellular Ca^(2+) stores, and has an essential role in agonist-induced gallbladder muscle contraction. | Xingguo Zhong Jie Fu Kai Song Nairui Xue Renhua Gong Dengqun Sun Huilai Luo Wenzhu He Xiang Pan Bing Shen Juan Du | 2016 | Science China(Life Sciences)2016，59，4： | 1 |
| 5 | MicroRNA-29a inhibits cell migration and invasion via targeting Roundabout homolog1 in gastric cancer cells显示文摘 | Xueting Liu Jun Cai Yanjun Sun Renhua Gong Dengqun Sun Xingguo Zhong Shitao Jiang Xinmiao He Enwu Bao Liusheng Yang Yongxiang Li | 2015 | Molecular Medicine Reports2015，，3： | 1 |
| 6 | Bone Marrow Derivation of Interstitial Cells of Cajal in Small Intestine Following Intestinal Injury显示文摘 | Dengqun Liu Fengchao Wang Zhongmin Zou Shiwu Dong Junping Wang Xinze Ran Chunxue Li Chunmeng Shi Yongping Su Ronnie Gallagher | 2010 | Journal of Biomedicine and Biotechnology2010，，： | 1 |
| 7 | Engraftment of bone marrow-derived cells after nonlethal radiation in syngeneic C57BL/6mice显示文摘 | Wu Liao Tan Li Wang Yu Liu Dengqun Shi Chunmeng WuLiao TanLi WangYu LiuDengqun ShiChunmeng | 2015 | 中华放射医学与防护杂志2015，35，1： | 0 |
| 8 | Enhanced autophagy protects hepatic cells from radiation injury显示文摘 | Liu Lang Liu Dengqun Wang Yu Wang Ziwen Chen Zelin Chert Jie Han Xiao Liu Zujuan Zhang Aihua Shi Chunmeng | 2018 | 中华放射医学与防护杂志2018，38，5： | 0 |
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