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| 1 | Japanese Encephalitis Virus NS1' Protein Antagonizes Interferon Beta Production显示文摘Japanese encephalitis virus(JEV) is a mosquito-borne virus and the major cause of viral encephalitis in Asia. NS1', a52-amino acid C-terminal extension of NS1, is generated with a-1 programmed ribosomal frameshift and is only present in members of the Japanese encephalitis serogroup of flaviviruses. Previous studies demonstrated that NS1' plays a vital role in virulence, but the mechanism is unclear. In this study, an NS1' defected(rG66A) virus was generated. We found that rG66A virus was less virulent than its parent virus(pSA14) in wild-type mice. However, similar mortality caused by the two viruses was observed in an IFNAR knockout mouse model. Moreover, we found that rG66A virus induced a greater type Ⅰ interferon(IFN) response than that by pSA14, and JEV NS1' significantly inhibited the production of IFN-b and IFN-stimulated genes. Taken together, our results reveal that NS1' plays a vital role in blocking type I IFN production to help JEV evade antiviral immunity and benefit viral replication. | Dengyuan Zhou Fan Jia Qiuyan Li Luping Zhang Zheng Chen Zikai Zhao Min Cui Yunfeng Song Huanchun Chen Shengbo Cao Jing Ye | 2018 | Virologica Sinica2018，33，6： | 3 |
| 2 | Feature-based vehicle flow analysis and measurement for a real-time traffic surveillance system显示文摘 | Huang Dengyuan | 2012 | Journal of Information Hiding and Multimedia Signal Processing2012，，3： | 1 |
| 3 | N-soliton solutions and double Wronskian solution of the non-isospectral AKNS equation显示文摘 | Sun Yunpen Bi Jinbo Chen Dengyuan | 2005 | Chaos Solitons and Fractals2005，26，3： | 1 |
| 4 | Darboux transformation and soliton-like solutions of nonlinear Schr?dinger equations显示文摘 | Tiecheng Xia Xiaohong Chen Dengyuan Chen | 2005 | Chaos, Solitons and Fractals2005，，3： | 1 |
| 5 | Adaptive Wide Field-of-View Surveillance Based on an IP Camera on a Rotational Platform for At, tomatic Detection of Abandoned and Remove Objects显示文摘 | HU Wuchih HUANG Dengyuan CHEN Weihao | 2010 | ICIC Express Letters Part B:Applications2010，，1： | 1 |
| 6 | Optimal multi-level thresholding using a two-stage otsu optimization approach 显示文摘 | Huang Dengyuan Wang Chiahung | 2009 | Pattern Recognition Letters2009，30，： | 1 |
| 7 | Learning-based face detection by adaptive switching of skin color models and AdaBoost under varying illumination 显示文摘 | HUANG Dengyuan LIN Chunjih HU Wuchi | 2011 | Journal of Informa tion Hiding and Multimedia Signal Processing2011，2，3： | 1 |
| 8 | New double Wronskian solutions of the AKNS equation显示文摘 | Chen Dengyuan Zhang Dajun Bi Jinbo | | 0，，01： | 1 |
| 9 | n-Type silicon quantum dots and p-type crystalline silicon hetero-face solar cells显示文摘 | SANGWOOK PARK EUNCHEL CHO DENGYUAN SONG | | Solar Energy M0，，： | 1 |
| 10 | The exact solution to Boussinesq equation through a limiting procedure显示文摘 | Chen Dengyuan | 2007 | Physica A2007，373，： | 1 |
| 11 | 显示文摘 | Song Dengyuan Neuhaus D H Xia James | 2002 | Thin Solid Films2002，442，： | 1 |
| 12 | Adaptivewide field-of~view surveillance based on an IP camera on a rota-tional platform for automatic detection of abandoned and removeobjects 显示文摘 | HU Wuchih HUANG Dengyuan CHEN Weihao | 2010 | ICIC Express Letters Part B: Applications2010，，1： | 1 |
| 13 | Generalized double Casoratian solutions to the four-potential isospectral Ablowitz-Ladik equation显示文摘 | Chen Shouting Zhang Jianbing Chen Dengyuan | | 0，，11： | 1 |
| 14 | Investigation of Lateral Parameter Variations of Al-doped Zinc Oxide Films Prepared on Glass Substrates by rf Magnetron Sputtering显示文摘 | Song Dengyuan Widenborg Der Chn Winstonet 02 | 2002 | Solar Energy Materials and Solar Cells2002，73，1： | 1 |
| 15 | Structural,electrical and photovoltaic characterization of Si nano-crystals embedded SiC matrix and Si nanocrystals/c-Si heterojunction devices显示文摘 | SONG Dengyuan CHOA E C CONIBEERA G | 2008 | Solar Energy Materials and Solar Cells2008，92，4： | 1 |
| 16 | Backlund transformation and soliton solutions for the shallow water waves equation显示文摘 | ZHANG YI CHEN DENGYUAN | 2004 | Chaos Solitons & Fractals2004，20，2： | 1 |
| 17 | Optimal Multi-level Thresh- olding Using a Two-stage Otsu Optimization Approach显示文摘 | Huang Dengyuan Wang Chia-huang | 2009 | Pattern Recognition Letters2009，30，3： | 1 |
| 18 | Physical frame timeslot switching (PTS) in the single user-plane architecture network ( SUPANET ) 显示文摘 | XU Dengyuan ZENG Huashen LI Ji | 2005 | Parallel and Distributed Computing: Applications and Technologies2005，6，1： | 1 |
| 19 | k-constraint for the modified Kadomtsev-Petviashvili system显示文摘 | Chen Dengyuan | 2002 | J Math Phys2002，43，4： | 1 |
| 20 | Two dimensional full band and ensemble Monte Carlo simulation of wurtzite gan mesfets显示文摘 | GuoBaozeng Ravaioli U Song Dengyuan | 2004 | Microelectronics Journal2004，35，： | 1 |
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