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8篇 您的检索式:作者名="Dent Andrew"
    题名 作者 年代 出处 被引量
1Hyperglycemia Affects Gastric Electrical Rhythm and Nausea During Intraduodenal Triglyceride Infusion显示文摘Geoffrey S. Hebbard Melvin Samsom Jane M. Andrews David Carman Ben Tansell Wei Ming Sun John Dent Michael Horowitz 1997Digestive Diseases and Sciences1997,,3:1
2Characterisation of salt films on dissolving metal surfaces in artificial corrosion pits via in situ synchrotron X-ray diffraction显示文摘Trevor Rayment Alison J. Davenport Andrew J. Dent Jean-Philippe Tinnes Richard J.K. Wiltshire Christopher Martin Graham Clark Paul Quinn J. Fred W. Mosselmans 2008Electrochemistry Communications2008,,6:1
3The effects of fuel chemistry and feedstock powder structure on the mechanical and tribological properties of HVOF thermal sprayed WC-Co coatings with very fine structures显示文摘Qiao Yunfei Traugott E Fischer Andrew Dent 2003Surface and Coatings Technology2003,172,1:1
4The effects of fuel chemistry and feedstock powder structure on the mechanical and tribological properties of HVOF thermal-sprayed WC–Co coatings with very fine structures显示文摘Yunfei Qiao Traugott E Fischer Andrew Dent 2003Surface & Coatings Technology2003,,1:1
5The effects of fuel chemistry and feedstock powder structure on the mechanical and tribological properties of HVOF thermal-sprayed WC-Co coatings with very fine structures 显示文摘Qiao Yunfei Traugott E F Andrew Dent 2003Surface and Coatings Technology2003,172,:1
6Comparison of HVOF and plasma-sprayed alumina/titania coatings-microstructure,mechanical,properties and abrasion behavior显示文摘Liu Yourong Fischer Traugott E Dent Andrew 2003Surface and Coatings Technology2003,167,1:1
7Comparison of HVOF and plasma-sprayed aluminay/titania coatings-microstructure,mechanical properties and abrasion behavior显示文摘Liu Y R Traugott E Fischer Andrew Dent 2003Surface and Coatings Technology2003,167,1:1
8Kinase inhibitors:look beyond the label on the bottle显示文摘The majority of scientists working in the field of cancer experimental therapeutics recognize that many drugs that claim to be“specific”for one target enzyme in fact regulate to varying degrees the activities of other additional protein targets.Some of these targets are known and are recognized as being an essential component of a drug’s biology.However,many other targets fall into the category of“unknown unknowns”.Thus,the collective therapeutic outcome for almost all clinically relevant drugs is reliant on both the claimed primary and secondary“on”targets as well as some of the unexpected unknown“off”targets.This review discusses the biology of several FDA approved cancer therapeutic drugs whose initial reported targets only represented the tip-of-the-iceberg in terms of how each agent acted as an anti-tumor drug.The review also discusses a putative thorough pre-visualization methodology for drug-based research,prior to executing any wet work.These approaches should be performed in an agnostic fashion and be based in part on the clinically safe drug’s C max and its area under the curve in a patient.Based on tumor heterogeneity,considerations of how to approach developmental therapeutics in the age of“personalized medicine”are also discussed.Paul Dent Andrew Poklepovic Laurence Booth John F.Hancock 2019Cancer Drug Resistance2019,2,4:0
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