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| 1 | Radiofrequency ablation or microwave ablation combined with transcatheter arterial chemoembolization in treatment of hepatocellular carcinoma by comparing with radiofrequency ablation alone显示文摘Objective:To compare radiofrequency ablation(RFA) or microwave ablation(MWA) and transcatheter arterial chemoembolization(TACE) with RFA or MWA monotherapy in hepatocellular carcinoma(HCC).Methods:A prospective,randomized,controlled trial was conducted on 94 patients with HCC ≤7 cm at a single tertiary referral center from June 2008 to June 2010 at the Department of Hepatobiliary Surgery,the Second Affiliated Hospital of Southeast University.The patients were randomly assigned into the TACERFA or TACE-MWA(combined treatment group) and the RFA-alone or MWA-alone groups(control group).The primary end point was overall survival.The secondary end point was recurrence-free survival,and the tertiary end point was adverse effects.Results:Until the time of censor,17 patients in the TACE-RFA or TACE-MWA group had died.The median follow-up time of the patients who were still alive for the TACE-RFA or TACE-MWA group was 47.5±11.3 months(range,29 to 62 months).The 1-,3- and 5-year overall survival for the TACE-RFA or TACE-MWA group was 93.6%,68.1% and 61.7%,respectively.Twenty-five patients in the RFA or MWA group had died.The median follow-up time of the patients who were still alive for the RFA or MWA group was 47.0±12.9 months(range,28 to 62 months).The 1-,3- and 5-year overall survival for the RFA or MWA group was 85.1%,59.6% and 44.7%,respectively.The patients in the TACE-RFA or TACE-MWA group had better overall survival than the RFA or MWA group [hazard ratio(HR),0.526;95% confidence interval(95% CI),0.334-0.823;P=0.002],and showed better recurrence-free survival than the RFA or MWA group(HR,0.582;95% CI,0.368-0.895;P=0.008).Conclusions:RFA or MWA combined with TACE in the treatment of HCC ≤7 cm was superior to RFA or MWA alone in improving survival by reducing arterial and portal blood flow due to TACE with iodized oil before RFA. | Yongxiang Yi Yufeng Zhang Qiang Wei Liang Zhao Jianbo Han Yan Song Ying Ding Guilan Lu Junmao Liu Huaiying Ding Feng Dai Xiaojun Tang | 2014 | Chinese Journal of Cancer Research2014，26，1： | 29 |
| 2 | Microbial response to CaCO_3 application in an acid soil in southern China显示文摘Calcium carbonate(CaCO_3) application is widely used to ameliorate soil acidification. To counteract soil and bacterial community response to CaCO_3 application in an acidic paddy soil in southern China, a field experiment was conducted with four different dosages of CaCO_3 addition, 0, 2.25, 4.5 and 7.5 tons/ha, respectively. After one seasonal growth of rice, soil physicochemical properties, soil respiration and bacterial communities were investigated. Results showed that soil p H increased accordingly with increasing dose of CaCO_3 addition, and 7.5 tons/ha addition increased soil p H to neutral condition. Moderate dose of CaCO_3 application(4.5 tons/ha) significantly increased soil dissolved organic carbon(DOC) and dissolved organic nitrogen(DON) content, enhanced soil respiration, while the excessive CaCO_3 application(7.5 tons/ha) decreased these soil properties. High-throughput sequencing results illustrated that moderate dose of CaCO_3 application increased the richness and alpha diversity of soil bacterial community. Compared with control, the relative abundance of Anaerolineaceae family belonging to Chloroflexi phylum increased by 38.7%, 35.4% and 24.5% under 2.25, 4.5 and 7.5 tons/ha treatments, respectively.Redundancy analysis(RDA) showed that soil p H was the most important factor shaping soil bacterial community. The results of this study suggest that proper dose of CaCO_3 additions to acid paddy soil in southern China could have positive effects on soil properties and bacterial community. | Anning Guo Longjun Ding Zhong Tang Zhongqiu Zhao Guilan Duan | 2019 | Journal of Environmental Sciences2019，31，5： | 7 |
| 3 | Hybrid-integratedmich- elson fiber optic accelerometer显示文摘 | Wu Bo Chen Caihe Ding Guilan | 2004 | Optical Engineering2004，43，2： | 1 |
| 4 | Research and Fabrication on Integrated Optical Chip of Hybrid-Integrated Optical Acceleration Seismic Geophone显示文摘 | Chen Caihe Wu Bo Ding Guilan | 2002 | Proc SPIE2002，4919，： | 1 |
| 5 | Hybrid-integrated Michelson fiber optic accelerometer显示文摘 | Wu Bo Chen Caihe Ding Guilan | 2004 | Optical Engineering2004，43，2： | 1 |
| 6 | Michelson fiber-optic allelerometer显示文摘 | Chen Caihe Ding Guilan Zhang Delong | 1998 | Review Scientific Instrument1998，69，9： | 1 |
| 7 | Hybrid-integrated Michelson fiber optic accelerometer显示文摘 | Wu Bo Chen Caihe Ding Guilan | 2004 | Optical Engineering2004，43，2： | 1 |
| 8 | Hybrid-integrated Michelson fiber optic accelerometer显示文摘 | Wu Bo Chen Caihe Ding Guilan | 2004 | Optical Engineering2004，43，2： | 1 |
| 9 | Co-occurrence of genes for antibiotic resistance and arsenic biotransformation in paddy soils显示文摘Paddy soils are potential hotspots of combined contamination with arsenic(As) and antibiotics, which may induce co-selection of antibiotic resistance genes(ARGs) and As biotransformation genes (ABGs), resulting in dissemination of antimicrobial resistance and modification in As biogeochemical cycling. So far, little information is available for these coselection processes and specific patterns between ABGs and ARGs in paddy soils. Here, the16S rRNA amplicon sequencing and high-throughput quantitative PCR and network analysis were employed to investigate the dynamic response of ABGs and ARGs to As stress and manure application. The results showed that As stress increased the abundance of ARGs and mobile genetic elements (MGEs), resulting in dissemination risk of antimicrobial resistance. Manure amendment increased the abundance of ABGs, enhanced As mobilization and methylation in paddy soil, posing risk to food safety. The frequency of the co-occurrence between ABGs and ARGs, the host bacteria carrying both ARGs and ABGs were increased by As or manure treatment, and remarkably boosted in soils amended with both As and manure. Multidrug resistance genes were found to have the preference to be co-selected with ABGs, which was one of the dominant co-occurring ARGs in all treatments, and manure amendment increased the frequency of Macrolide-Lincosamide-Streptogramin B resistance(MLSB) to co-occur with ABGs. Bacillus and Clostridium of Firmicutes are the dominant host bacteria carrying both ABGs and ARGs in paddy soils. This study would extend our understanding on the co-selection between genes for antibiotics and metals, also unveil the hidden environmental effects of combined pollution. | Huiling Cui Dong Zhu Longjun Ding YifeiWang Jianqiang Su Guilan Duan Yongguan Zhu | 2023 | Journal of Environmental Sciences2023，，3： | 1 |
| 10 | Broadband Michelson fiber-optic accelerometer显示文摘 | Chen Caihe Zhang Delong Ding Guilan | 1999 | Applied optics1999，38，4： | 1 |
| 11 | Michelson fiber optic accelerometer显示文摘 | Caihe Chen Guilan Ding Delong Zhang | | Review of Scientific Instruments0，69，9： | 1 |
| 12 | Broadband Michelson fiber-optic accelerometer显示文摘 | Caihe Chen Delong Zhang Guilan Ding | 1999 | Applied Optics1999，38，4： | 1 |
| 13 | Broad band and Michelson fiber-optic accelerometer 显示文摘 | Zhang Delong Ding Guilan | 1999 | Appl Opt1999，38，4： | 1 |
| 14 | Research and fabrication on integrated optical chip of hybrid-integrated optical acceleration seismic geophone 显示文摘 | Wu Bo Ding Guilan | 2002 | Proc SPIE2002，4919，： | 1 |
| 15 | Michelson fiberoptic accelerometer 显示文摘 | Caihe Chen Guilan Ding Delong Zhang and Yunming Cui | 1998 | Review of Scientific Instruments1998，69，： | 1 |
| 16 | Broadband Michelson fiber-optic accelerometer显示文摘 | Caihe Chen Guilan Ding Delong Zhang and Yunming Cui | 1999 | Applied Optics February1999，38，4： | 1 |
| 17 | An Experimental Calibration on the Sphalerite-Galena Sulfur Isotope Geothermometer显示文摘A new experimental calibration was undertaken in this study to get a more reliable sphalerite-galenasulfur isotope geothermometer. The experimental conditions selected in study were very similar to those of naturalhydrothermal solution. The high-precision SF6 method was used in sulfur isotope analyses. The obtained calibrationcurve for sulfur isotope fractionation between sphalerite and galena can be expressed with the equation 1000lnαSp-Gn=0.74×106T-2+0.08. | DING Tiping, ZHANG Chengxin, WAN Defang, LIU Zhijian and ZHANG Guilan Institute of Mineral Resources, Chinese Academy of Geological Sciences, 26 Baiwanzhuang Rd.,Beijing 100037 | 2003 | Acta Geologica Sinica(English Edition)2003，77，4： | 0 |
| 18 | Quartz-Ferberite Oxygen Isotope Geothermometer and Its Geological Applications显示文摘Experiments for oxygen isotope exchange between ferberite and water were carried out and the followingequation on oxygen isotope fractionation between ferberite and water against temperature was obtained:Combining this equation with the equation of Clayton et al. (1972) on oxygen isotope fractionation be-tween quartz and water, an equation on oxygen isotope fractionation between quartz and ferberite was ob-tained:The Bigeleison-Mayer function method was used to calculate the oxygen isotope fractionation betweenquartz and ferberite. The theoretical curve obtained agrees with the experimental calibration results quite wellin the temperature range of study.The above calibrated equation has been used in 5 world famous tungsten deposits to determine their tem-peratures of formation. The results show that the temperature range for an idividual deposit determined by thisgeothermometer agrees with those obtained from fluid inclusion determination and other isotopegeothermometers. | Ding Tiping Liu Yushan Wan Defang Liu Zhijian Li Jincheng Zhang Guilan Institute of Mineral Deposits, Chinese Academy of Geological Sciences, Beijing | 1992 | Acta Geologica Sinica(English Edition)1992，66，3： | 0 |
| 19 | Preliminary Design of a Submerged Support Structure for Floating Wind Turbines显示文摘Cost-effective floating wind turbines with efficient installations are highly desired in deep waters(>50 m).This paper presents a submerged floating offshore wind turbines(SFOWT)concept for intermediate water depths(50-200 m).The performance of SFOWTs can be improved through a judicious choice of configuration,pretension,and mooring line layout.Four SFOWTs with different configurations and a similar mass,named Cyl-4,Cub-4,Cyl-3,and Hex-3,were designed and analyzed.The responses of the four SFOWTs were predicted under operational condition and extreme condition.The results show that the four SFOWTs exhibited good performance under both conditions.The effect of platform configurations on power output was negligible under the operational condition.Under the extreme condition,among the four SFOWTs,the mean bending moments at the tower base were very close,while the maximum values differed by up to 21.5%,due to the configurations.The effect of wind-wave misalignment under the extreme condition was further analyzed.In general,the motion performances of the four-pontoon SFOWTs,Cyl-4 and Cub-4,were superior to those of the three-pontoon SFOWTs,Cyl-3 and Hex-3.Optimization studies of the mooring system were carried out on Cub-4 with different mooring line pretensions and four mooring layouts.The optimized Cub-4 could reduce the maximum motion responses in the surge,heave,and yaw by 97.7%,91.5%,and 98.7%,respectively. | LE Conghuan ZHANG Jian DING Hongyan ZHANG Puyang WANG Guilan | 2020 | Journal of Ocean University of China2020，19，6： | 0 |
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