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| 1 | Prospective evaluation of a new device for the treatment of anal fistulas显示文摘AIM: To evaluate the safety of the implantation of a new device for the treatment of anal fistulas. The short-term clinical efficacy was also assessed. METHODS: This study took place at a tertiary care university hospital. Patients with a complex anal fistula of cryptoglandular origin were enrolled in the study and were treated with insertion of the new device. All patients were evaluated by clinical and physical examination, including an endoanal ultrasound at the baseline, and then at the 2 wk and 1, 2, 3 and 6-mo follow-up visits. RESULTS: Morbidity, continence status, and success rate were the main outcome measures. Ten patients underwent the placement of the new device. The fistulas were transphincteric in eight patients and extrasphincteric in the remaining two. The median duration of the surgical procedure was 34.5(range, 27-42) min. Neither intra- nor postoperative complications occurred, and all patients were discharged the day after the procedure. At the 6-mo follow-up evaluation, the final success rate was 70%. Three failures were registered: a device expulsion(on the 10 th postoperative day), the persistence of inflammatory tissue around the fistula tract(at the 2-mo follow up), and the persistence of serum discharge(at the 6-mo follow up). No patient experienced any change incontinence, as assessed by the Cleveland Clinic Fecal Incontinence score. CONCLUSION: The technical procedure is simple and has low risk of perioperative morbidity. The pre- and post-operative continence status did not change in any of the patients. The initial results at the 6-mo follow up seem to be promising. However, a longer follow-up period and a larger sample size are needed to confirm these preliminary results. | Carlo Ratto Francesco Litta Lorenza Donisi Angelo Parello | 2016 | World Journal of Gastroenterology2016，22，30： | 2 |
| 2 | Metastatic tumors to the stomach: Clinical and endoscopicfeatures显示文摘AIM: To evaluate the clinical and endoscopic patterns in a large series of patients with metastatic tumors in the stomach. METHODS: A total of 64 patients with gastric meta- stases from solid malignant tumors were retros- pectively examined between 1990 and 2005. The clinicopathological findings were reviewed along with tumor characteristics such as endoscopic pattern, location, size and origin of the primary sites. RESULTS: Common indications for endoscopy were anemia, bleeding and epigastric pain. Metastases presented as solitary (62.5%) or multiple (37.5%) tumors were mainly located in the middle or upper third of stomach. The main primary metastatic tumors were from breast and lung cancer and malignant melanoma. CONCLUSION: As the prognosis of cancer patients has been improving gradually, gastrointestinal (GI) metastases will be encountered more often. Endoscopic examinations should be conducted carefully in patients with malignancies, and endoscopic biopsies and information on the patient’s clinical history are useful for correct diagnosis of gastric metastases. | Giovanni D De Palma Stefania Masone Maria Rega Immacolata Simeoli Mario Donisi Pietro Addeo Loredana Iannone Vincenzo Pilone Giovanni Persico | 2006 | World Journal of Gastroenterology2006，12，45： | 2 |
| 3 | Rhodococcus equi infection in HIV-infected patients 显示文摘 | Donisi A Suardi MG Casari S | 1996 | AIDS1996，10，4： | 1 |
| 4 | Evaluation of Transanal Hemorrhoidal Dearterialization as a Minimally Invasive Therapeutic Approach to Hemorrhoids显示文摘 | Carlo Ratto Lorenza Donisi Angelo Parello Francesco Litta Giovanni Battista Doglietto | 2010 | Diseases of the Colon & Rectum2010，，： | 1 |
| 5 | Evaluation of Transanal Hemorrhoidal Dearterialization as a Mini- mally Invasive Therapeutic Approach to Hemorrhoids 显示文摘 | Ratto C Donisi L Parello A | 2010 | Dis Colon Rectum2010，53，： | 1 |
| 6 | Factors affecting false-negative rates on ex vivo sentinel node mapping in colorectal cancer显示文摘 | Sommariva A Donisi PM Gnocato B | 2010 | Eur J Surg Oncol2010，36，2： | 1 |
| 7 | Factors affecting false-negative rates on ex vivo sentinel lymph node mapping in colorectal cancer显示文摘 | Sommariva A Donisi PM Gnocato B | 2010 | Eur J Surg Oncol2010，36，2： | 1 |
| 8 | Rhodococcus equi infection in HIV-infected oatients显示文摘 | Donisi A Suardi MG Gasari S | 1996 | AIDS1996，10，4： | 1 |
| 9 | Evaluation of transanal hemorrhoidal dearterialization as a minimally invasive thera- peutic approach to hemorrhoids显示文摘 | Ratto C Donisi L Parello A | 2010 | Dis Colon Rectum2010，53，5： | 1 |
| 10 | Rhodococcus equi infection in HIV-infected patients显示文摘 | Donisi A Suardi MG Caasari S | 1996 | AIDS1996，10，4： | 1 |
| 11 | Pyogenic liver abscess:is drainage always possible显示文摘 | SOMMARIVA A DONISI P M LEONI G | 2006 | Eur J Gastroenterol Hepatol2006，18，： | 1 |
| 12 | Analysis of limbal stem cell deficiency by corneal impression cytology显示文摘 | Donisi PM Rama P Fasolo A Ponzin D | 2003 | Cornea2003，22，： | 1 |
| 13 | Evaluation of transanalhemorrhoidal dearterialization as a minimally invasivetherapeutic approach to hemorrhoids 显示文摘 | Ratto C Donisi L Parello A | 2010 | Dis Colon Rectum2010，53，： | 1 |
| 14 | Factors affecting false- negative rates on ex vivo sentinel node mapping in colorectal cancer 显示文摘 | Sommariva A Donisi PM Gnocato B | 2010 | Eur J Surg Oncol2010，36，2： | 1 |
| 15 | Factors 'affecting false - negative rates on ex vivo sentinel node mapping in coloreetal cancer 显示文摘 | Sommariva A Donisi PM Gnocato B | 2010 | Eur J Surg Oneol2010，36，2： | 1 |
| 16 | Evaluation of transanal hemorrhoidal dearterialization as a minimally invasive therapeutic approach to hemorrhoids显示文摘 | Ratto C Donisi L Parello A | 2010 | Dis colon rectum2010，53，5： | 1 |
| 17 | Distal Doppler-guided dearterialization,is highly effective in treating haemorrhoids by transanal hae-morrhoidaldearterialization显示文摘 | Ratto C Donisi L | 2012 | Colorectal Dis2012，14，： | 1 |
| 18 | Analysis of limbal stem cell deficiency by corneal impression cytology显示文摘 | Donisi PM Rama P Fasolo A | | 0，，： | 1 |
| 19 | Borderline resectable pancreatic cancer:Certainties and controversies显示文摘Borderline resectable(BR)pancreatic ductal adenocarcinoma(PDAC)is currently a well-recognized entity,characterized by some specific anatomic,biological and conditional features:It includes patients with a stage of disease intermediate between the resectable and the locally advanced ones.The term BR identifies a tumour with an aggressive biological behaviour,on which a neoadjuvant approach instead of an upfront surgery one should be preferred,in order to obtain a radical resection(R0)and to avoid an early recurrence after surgery.Even if during the last decades several studies on this topic have been published,some aspects of BR-PDAC still represent a matter of debate.The aim of this review is to critically analyse the available literature on this topic,particularly focusing on:The problem of the heterogeneity of definition of BR-PDAC adopted,leading to a misinterpretation of published data;its current management(neoadjuvant vs upfront surgery);which neoadjuvant regimen should be preferably adopted;the problem of radiological restaging and the determination of resectability after neoadjuvant therapy;the post-operative outcomes after surgery;and the role and efficacy of adjuvant treatment for resected patients that already underwent neoadjuvant therapy. | Gennaro Nappo Greta Donisi Alessandro Zerbi | 2021 | World Journal of Gastrointestinal Surgery2021，13，6： | 1 |
| 20 | Lymphoid follicule in gastric mucosa of Helicobacter pylori infected patients regression 6-12 months after eradication显示文摘 | Battglia G Lecis E Donisi PM | 1995 | Gut1995，37，1： | 1 |
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