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| 1 | Power enhancement of an actively cont rolled battery ultracapacitorhybrid显示文摘 | GAO Lijun DOU GAL R A LIU Shengyi | | 0，，01： | 1 |
| 2 | 4-1 Dielectronic Recombination of 36Ar15+ and 112Sn34+ at the CSRm显示文摘The total recombination rate coefficients of lithium-like 36Ar15+ ions have been measured by employing the electron-ion merged-beams technique at the heavy ion storage ring CSRm at IMP[1]. Fig. 1 (a) shows the DR spectrum for electron energy from 0 to 35 eV in the center-of-mass (c.m.) frame involving all the DR resonances associated with 2s1=2!2p1=2 and 2s1=2!2p3=2 excitations. | Huang Zhongkui Ma Xinwen Wen Weiqiang Wang Hanbing Chuai Xiaoya Dou Lijun Zhu Xiaolong Xu Xin Zhu Linfan Xu Weiqing Mao Lijun Li Jie Zhang Xiaohu Ma Xiaoming Yan Tailai Yang Jiancheng Yuan Youjin Xiao Guoqing Xia Jiawen Xie Luyou Dong Chenzhong DR collaboration | 2015 | IMP & HIRFL Annual Report2015，，1： | 0 |
| 3 | 4-6 Theoretical Study of Dielectronic Recombination of Li-Like 36Ar15+ Ions显示文摘Dielectronic recombination (DR) is an important electron–ion recombination process. This process is generallyconsidered to occur in two steps,e??+Aq+![A(q??1)+]![A(q??1)+]+nhv ; (1) where in the first step a free electron is captured simultaneously with the excitation of a bound electron. In the second step the doubly-excited ion is stabilized by emitting photons. | Dou lijun Xie Luyou Huang Zhongkui Dong Chenzhong Ma Xinwen | 2015 | IMP & HIRFL Annual Report2015，，1： | 0 |
| 4 | 4-8 Dielectronic Recombination of 112Sn35+ Ions at the CSRm显示文摘The total recombination rate coefficient of Phosphorus-like 112Sn35+ have been measured at the main cooler storage ring (CSRm) employing the electron-ion merged-beams technique. The Phosphorus-like 112Sn35+ ions were injected into the CSRm at an energy of 3.7 MeV/u with a typical current of 50 eA, and the momentum spread of the ion beam is 210?4 after several seconds of cooling. | Xu Xin Wang Shuxing Zhu Linfan Huang Zhongkui Ma Xinwen Wen Weiqiang Wang Hanbing Chuai Xiaoya Dou Lijun Zhu Xiaolong Zhao Dongmei Yuan Youjin Mao Lijun Li Jie Ma Xiaoming Yan Tailai Yang Jiancheng Xia Jiawen | 2015 | IMP & HIRFL Annual Report2015，，1： | 0 |
| 5 | An open-label evaluation of safety and tolerability of coformulated bictegravir/emtricitabine/tenofovir alafenamide for post-exposure prophylaxis following potential exposure to human immunodeficiency virus-1显示文摘Background: Single-tablet regimen (STR) provides a convenient once-daily regimen for the prevention of human immunodeficiency virus (HIV) infection. Here, we investigated the safety and tolerability of coformulated bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) as a three-drug, STR for post-exposure prophylaxis (PEP) in Chinese individuals.Methods: This was a prospective, open-label, single-arm trial conducted in a sexually transmitted diseases and acquired immunodeficiency syndrome clinic of a tertiary hospital in Beijing, China. Adults requiring PEP were prescribed BIC/FTC/TAF one pill once a day for 28 days. Clinical and laboratory data were collected and analyzed at baseline, weeks 2, 4, 8, 12, and 24.Results: Of 112 participants enrolled in the study, 109 (97.3%) were male and the mean age was 30 ± 8 years. PEP completion was 96.4% (95% confidence interval: 91.1-99.0%). Two participants stopped PEP after 2 days because the source partner was identified as HIV uninfected. One participant was excluded due to hepatitis B virus infection according to the exclusion criteria. One discontinued due to the participant’s decision. No participant acquired HIV through week 24. Adherence was 98.9% (standard deviation [SD]: 3.3%) by self-reporting and 98.5% (SD: 3.5%) by pill count. Only five participants experienced mild clinical adverse events attributed to the study drug (including headache, diarrhea, and nausea) and four participants had elevated serum creatinine (grade 1).Conclusions: A once daily, STR of BIC/FTC/TAF used as PEP was safe and well-tolerated with a high rate of completion and adherence in Chinese. BIC/FTC/TAF may be a good option for PEP. | An Liu Ruolei Xin Hongwei Zhang Lili Dai Ruojun(Esther)Wu Xi Wang Aixin Li Wei Hua Jianwei Li Ying Shao Yue Gao Zhangli Wang Jiangzhu Ye Gulimila A bu dou re xi ti Zaicun Li Lijun Sun | 2022 | Chinese Medical Journal2022，135，22： | 0 |
| 6 | 储存环CSRm上的类硼Ar^(13+)离子的低能双电子复合实验研究显示文摘Based on the successful dielectronic recombination(DR)experiments with intermediate charge state ions of Belike Ar^(14+[1]) and Ca^(16+[2]) at the CSRm,we are preparing the precision spectroscopy of DR experiments with highly charged ions and even radioactive ions at the CSRe.A test electron-ion recombination experiment of Boron-like Ar13+ions was performed with a section of the new electron beam energy detuning system,which will be installed at the CSRe.Fig.1 presents the measured and also the calculated DR spectra for B-like Ar^(13+) from 0 to 3 eV.The experimental result indicates that the new detuning system is more stable and has a higher energy resolution than the previous detuning system used at the CSRm.It paves the way for the upcoming DR experiments with highly charged heavy ions at the CSRe.In addition,the flexible atomic code(FAC)was employed to calculate the DR resonance strengths of Boron-like Ar^(13+) to compare with the experimental result. | Huang Zhongkui Wen Weiqiang Wang Shuxing Li Shuang Wang Hanbing Nadir Khan Dou Lijun Zhu Xiaolong Mao Lijun Li Jie Ma Xiaoming Yin Dayu Mao Ruishi Yuan Youjin Yang Jiancheng Chen Chongyang Zhu Linfan Ma Xinwen | 2018 | IMP & HIRFL Annual Report2018，，1： | 0 |
| 7 | 重离子冷却储存环CSRm上的类铍^(40)Ar^(14)+离子的双电子复合和三电子复合显示文摘Electron-ion recombination of Be-like ^(40)Ar^(14)+has been measured by employing the electron-ion merged-beams method at the cooler storage ring CSRm.The measured absolute recombination rate coefficients for collision energies from 0 to 60 eV are presented in Fig.1,covering all dielectronic recombination(DR)resonances associated with 2s^(2)→2s2p core transitions.In addition,strong trielectronic recombination(TR)resonances associated with 2s^(2)→2p^(2) core transitions were observed.Both DR and TR processes lead to series of peaks in the measured recombination spectrum,which have been identified by the Rydberg formula.Theoretical calculations of recombination rate coefficients were performed using the state-of-the-art multi-configuration Breit-Pauli(MCBP)atomic structure code AUTOSTRUCTURE to compare with the experimental results.The plasma rate coefficients for DR+TR of Ar14+were deduced from the measured electron-ion recombination rate coefficients in the temperature range from 10^(3) to 10^(7) K,and compared with calculated data from the literature. | Huang Zhongkui Wen Weiqiang Wang Hanbing Xu Xin Zhu Linfan Wang shuxing Dou Lijun Zhu Xiaolong Yao ke Xu Tianheng Mao Lijun Li Jie Yang Jiancheng Yuan Youjinand Ma Xinwen | 2017 | IMP & HIRFL Annual Report2017，，1： | 0 |
| 8 | MiR-194-5p suppresses the warburg effect in ovarian cancer cells through the IGF1R/PI3K/AKT axis显示文摘Background:The Warburg effect is considered as a hallmark of various types of cancers,while the regulatory mechanism is poorly understood.Our previous study demonstrated that miR-194-5p directly targets and regulates insulin-like growth factor1 receptor(IGF1R).In this study,we aimed to investigate the role of miR-194-5p in the regulation of the Warburg effect in ovarian cancer cells.Methods:The stable ovarian cell lines with miR-194-5p overexpression or silencing IGF1R expression were established by lentivirus infection.ATP generation,glucose uptake,lactate production and extracellular acidification rate(ECAR)assay were used to analyze the effects of aerobic glycolysis in ovarian cancer cells.Gene expression was analyzed by quantitative polymerase chain reaction(qPCR)and western blot.Immunohistochemistry assays were performed to assess the expression of the IGF1R protein in ovarian cancer tissues.Results:Overexpression of miR-194-5p or silencing IGF1R expression in ovarian cancer cells decreases ATP generation,glucose uptake,lactate production,and ECAR and inhibits both the mRNA and protein expression of PKM2,LDHA,GLUT1,and GLUT3.While the knockdown of miR-194-5p expression led to opposite results.Overexpression of miR-194-5p or silencing IGF1R expression suppressed the phosphatidylinositol-3-kinase/protein kinase B(PI3K/AKT)pathway,whose activation can sustain aerobic glycolysis in cancer cells,and the knockdown of miR-194-5p expression promoted the activation of the PI3K/AKT pathway.Conclusion:Our results suggest that miR-194-5p can inhibit the Warburg effect by negative regulation of IGF1R and further repression of the PI3K/AKT pathway,which provides a theoretical basis for further test of miR-194-5p as a target in the treatment of ovarian cancer. | LIJUN DU KAIKAI DOU NIANHAI LIANG JIANMIN SUN RU BAI | 2023 | BIOCELL2023，47，3： | 0 |
| 9 | 3-2 Dielectronic Recombination of Be-like 40Ar14+at the CSRm显示文摘The total recombination rate coefficients of Be-like 40Ar14+ions have been measured by employing the electron-ion merged-beams technique at the heavy ion storage ring CSRm at IMP.Fig.1 shows the recombination spectrum for electron energy from 0 to 58 eV in the center-of-mass frame.The resonant capture,involving the core excitation of an electron and two electrons,which is termed dielectronic recombination(DR)and trielectronic recombination(TR)individually and leads to series of peaks,have been preliminarily identified by extending downward in energy from their series limits with the Rydberg formula[1]. | Huang Zhongkui Wen Weiqiang Wang Hanbing Dou Lijun Zhu Xiaolong Xu Xin Zhu Linfan Wang Shuxing Xu Weiqing Yao ke Xu Tianheng YangYang Mao Lijun Li Jie Yang Jiancheng Yuan Youjin Ma Xinwen | 2016 | IMP & HIRFL Annual Report2016，，1： | 0 |
| 10 | 3-6 A Novel Method by Employment of RF-buncher to Study Electron-ion Recombination at Ultra-low Collision Energy at CSRe显示文摘Heavy-ion storage rings equipped with electron coolers have been extensively used for electron-ion recombination studies.For dielectronic recombination(DR)experiments at the CSR,electron cooler is used for cooling of the ion beams as well as for electron target,where electron ion collision energy is detuned by changing the cooler cathode voltage.However,the absolute collision energy close to the cooling point could not be determined precisely in the recent^40Ar^14+DR experiment at the CSRm.Therefore,a novel method by utilizing a RF-buncher instead of the electron cooler to detune collision energy for electron-ion recombination measurement is proposed in this work. | Xu Tianheng Wen Weiqiang Huang Zhongkui Wang Hanbing Dou Lijun Khan Nadir Yao Ke Ma Xinwen | 2016 | IMP & HIRFL Annual Report2016，，1： | 0 |
| 11 | 3-11 Dielectronic Recombination of 56Fe^17+at the CSRm显示文摘The ionization and heating of the media surrounding accretion-powered compact sources,such as cataclysmic variables,X-ray binaries,and active galactic nuclei,are dominated by photoionization.Theoretical models of photo ionized gases show that the ionization structure is determined by photoionization balanced by radiative recombination(RR)and dielectronic recombination(DR).At low electron temperature existing in photo ionized gases with cosmic abundances,DR proceeds primarily via nlj→nl′j′excitations of core electrons(Δn=0). | Khan Nadir Huang Zhongkui Wen Weiqiang Xu Xin Wang Shuxing Wang Hanbing Dou Lijun Zhu Xiaolong Mao Lijun Li Jie Ma Xiaoming Yang Jiancheng Yuan Youjin Zhu Linfan Ma Xinwen | 2016 | IMP & HIRFL Annual Report2016，，1： | 0 |
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